Zakudya za Khansa ya Ovarian!

Introduction

Zakudya za Khansa ya Ovarian ziyenera kukhala zamunthu aliyense payekhapayekha komanso zimayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Kwa Khansa ya Ovarian kodi zilibe kanthu zomwe masamba, zipatso, mtedza, mbewu zomwe munthu amadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Ovarian Cancer kodi zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa ngati Ovarian Cancer?

Mwachitsanzo, kodi zilibe kanthu ngati Kolifulawa wamasamba amadyedwa kwambiri poyerekeza ndi Tomato wa Garden? Kodi zimapanga kusiyana kulikonse ngati chipatso cha Black Elderberry chimakonda kuposa makangaza? Komanso ngati kusankha kofananako kumapangidwa pa mtedza/mbewu monga Butternut over Brazil Nut komanso zamasamba monga Broad Bean over Chickpea. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ku Ovarian Cancer ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha chibadwa?

Inde! Zakudya zomwe mumadya ndizofunikira pa Khansa ya Ovarian!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Black Elderberry ili ndi zosakaniza zogwira ntchito Lycopene, Curcumin, Isoliquiritigenin, Quercetin, Myricetin. Ndipo makangaza ali ndi zosakaniza zogwira ntchito Curcumin, Isoliquiritigenin, Quercetin, Myricetin, Naringin ndi mwina ena.

Cholakwika chofala chomwe chimapangidwa posankha ndikusankha zakudya zoyenera kudya kwa Ovarian Cancer - ndikuwunika zosakaniza zosankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Ovarian Cancer.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonda Chakudya Chake cha Khansa ya Ovarian?

Zakudya zokometsera zamakhansa ngati Khansa ya Ovarian zimakhala ndi zakudya / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zikulimbikitsidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukatswiri mu biology ya Ovarian Cancer, sayansi yazakudya, genetics, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zomwe zimagwirizanitsidwa ndi zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa monga Ovarian Cancer

Makhansa onse monga Khansa ya Ovarian amatha kudziwika ndi njira yapadera yama biochemical - njira zosainira za Khansa ya Ovarian. Njira zama biochemical monga Kutupa, Chizindikiro cha NFKB, Malo Oyang'anira Ma cell Cycle, Apoptosis ndi gawo la tanthauzo la Ovarian Cancer. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza pa Khansa ya Ovarian chiyenera kuzindikirika ndi kusaina kwachilengedwe kwa wodwala aliyense yemwe ali ndi khansa komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa kwa Khansa ya Ovarian mukamamwa mankhwala a khansa Olaparib, ndipo zakudya zina ndi zowonjezera sizimalimbikitsidwa.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

TP53, MUC16, NF1, RYR2 ndi KMT2C ndi omwe adadziwika bwino kwambiri a khansa ya Ovarian. TP53 imanenedwa mu 29.2% ya odwala oyimira m'mayesero onse azachipatala. Ndipo MUC16 imanenedwa mu 3.2 %. Deta yophatikizidwa ya odwala imaphimba zaka kuyambira 26 mpaka 89. 0.0 % ya data ya odwala amadziwika kuti ndi amuna. Biology ya Khansa ya Ovarian pamodzi ndi ma genetics pamodzi amatanthauzira kuchuluka kwazomwe zimayimiridwa ndi njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Zakudya ndi Zowonjezera za Khansa ya Ovarian

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani masamba a CAULIFLOWER kapena GARDEN TOMATO?

Kolifulawa wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Isoliquiritigenin, Cinnamaldehyde, Psoralen, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kutupa, MAPK Signaling, TWEAK Signaling ndi MYC Signaling ndi ena. Kolifulawa amalangizidwa ku Khansa ya Ovarian pamene chithandizo cha khansa chopitilira ndi Olaparib. Izi ndichifukwa choti Kolifulawa amasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Olaparib.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Garden Tomato ndi Lycopene, Curcumin, Isoliquiritigenin, Quercetin, Myricetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA ndi zina. Tomato wa Garden ndiwosavomerezeka ku Khansa ya Ovarian pamene chithandizo cha khansa chikupitilira ndi Olaparib chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

KAULIFOLA WA MASABATA AMAKONZEDWA PA NTCHITO YA MUNDA WA NTCHITO YA Khansa ya Ovarian NDI MALANGIZO Olaparib.

Sankhani Chipatso POMEGRANATE kapena BLACK ELDERBERRY?

Chipatso Makangaza ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Isoliquiritigenin, Quercetin, Myricetin, Naringin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, Epithelial to Mesenchymal Transition, Kutupa ndi MAPK Signaling ndi ena. Makangaza amalimbikitsidwa kwa Khansa ya Ovarian pamene chithandizo cha khansa chopitilira ndi Olaparib. Izi zili choncho chifukwa makangaza amasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Olaparib.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Black Elderberry ndi Lycopene, Curcumin, Isoliquiritigenin, Quercetin, Myricetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA ndi MAPK Signaling ndi ena. Black Elderberry ndiyosavomerezeka kwa Khansa ya Ovarian pamene chithandizo cha khansa chikupitilira ndi Olaparib chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

ZIPATSO ZA KANGAZA AMAKONZEDWA PA BLACK ELDERBERRY WA Khansa ya Ovarian NDI MALANGIZO Olaparib.

Sankhani Nut BUTTERNUT kapena BRAZIL NUT?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Lycopene, Curcumin, Isoliquiritigenin, Myricetin, Caffeine. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, Epithelial to Mesenchymal Transition, Kutupa ndi MAPK Signaling ndi ena. Butternut amalangizidwa ku Khansa ya Ovarian pamene chithandizo cha khansa chopitilira ndi Olaparib. Izi zili choncho chifukwa Butternut imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Olaparib.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives ku Brazil Nut ndi Curcumin, Isoliquiritigenin, Cinnamaldehyde, Psoralen, Ellagic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Epithelial kupita ku Mesenchymal Transition, Kutupa ndi TWEAK Signaling ndi ena. Mtedza wa ku Brazil ndiwosavomerezeka ku Khansa ya Ovarian pamene chithandizo cha khansa chikupitilira ndi Olaparib chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.

BUTTERNUT AMAKONZEDWA PA NTHAWI YA KU BRAZIL PA Khansa ya Ovarian NDI MANKHWALA A Olaparib.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha chibadwa cha Khansa ya Ovarian kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani masamba KALE kapena AMERICAN POKEWEED?

Kale wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Lupeol, Indole-3-carbinol, Daidzein, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza kwa DNA, Cell Cycle, MAPK Signaling ndi MYC Signaling ndi ena. Kale akulimbikitsidwa pachiwopsezo cha Khansa ya Ovarian pomwe chiwopsezo cha chibadwa ndi KMT2C. Izi ndichifukwa choti Kale imawonjezera njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a American Pokeweed ndi Apigenin, Curcumin, Lupeol, Quercetin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA ndi MAPK Signaling ndi ena. American Pokeweed sivomerezedwa ngati chiopsezo cha Khansa ya Ovarian pamene chiwopsezo cha chibadwa ndi KMT2C chifukwa chimawonjezera njira zake.

MASAMBA KALE AMADALITSIDWA PA POKEWEED YA AMERICAN PA KMT2C GENETIC RISK OF CANCER.

Sankhani Chipatso RED RASPBERRY kapena PUMMELO?

Chipatso Chofiira cha Rasipiberi chili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Ellagic Acid, Lupeol, Quercetin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, P53 Signaling, DNA Repair ndi MYC Signaling ndi ena. Red Rasipiberi akulimbikitsidwa pachiwopsezo cha Khansa ya Ovarian pomwe chiwopsezo cha chibadwa ndi KMT2C. Izi ndichifukwa choti Red Rasipiberi imawonjezera njira zama biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu chipatso Pummelo ndi Apigenin, Curcumin, Lupeol, Lycopene, Quercetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga DNA Repair ndi Extracellular Matrix Remodeling ndi ena. Pummelo sichivomerezedwa ngati chiopsezo cha Khansa ya Ovarian pamene chiwopsezo cha chibadwa ndi KMT2C chifukwa chimawonjezera njira zake.

FRUIT RED RASPBERRY NDIKONDIKONZEDWA PA PUMMELO PA KMT2C GENETIC RISK OF CANCER.

Sankhani Nut BLACK WALNUT kapena CHESTNUT?

Black Walnut ili ndi zinthu zambiri zomwe zimagwira ntchito kapena bioactives monga Apigenin, Curcumin, Ellagic Acid, Lupeol, Quercetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, P53 Signaling, MAPK Signaling ndi Cell Cycle Checkpoints ndi ena. Black Walnut imalimbikitsidwa kuti ikhale pachiwopsezo cha Khansa ya Ovarian pamene chiopsezo chokhudzana ndi chibadwa ndi KMT2C. Izi ndichifukwa choti Black Walnut imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Chestnut ndi Apigenin, Curcumin, Ellagic Acid, Lupeol, Lycopene. Zosakaniza zomwe zimagwira zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza kwa DNA, Kukonzanso kwa Matrix Owonjezera ndi Ma cell Cycle Checkpoints ndi ena. Chestnut sivomerezedwa ngati chiopsezo cha Khansa ya Ovarian pamene chiwopsezo cha chibadwa ndi KMT2C chifukwa chimawonjezera njira zake.

WALNUT WAKUDA AKUKONZEDWA PA CHESTNUT PA KMT2C GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndizofunika kwambiri pa khansa monga Khansa ya Ovarian. Odwala a Khansa ya Ovarian ndi anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Khansa ya Ovarian, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Kolifulawa chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga zisankho kukhala kosavuta ndikuchotsa malingaliro onse poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha ku Ovarian Cancer?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Msk Impact 2017
• Pan-cancer kusanthula ma genomes onse.
• Isoliquiritigenin Imalepheretsa Khansa ya Ovarian Metastasis mwa Kutembenuza Epithelial-to-Mesenchymal Transition.
• Betulinic Acid Imapondereza Metastasis ya Khansa ya M'mawere potsata GRP78-Mediated Glycolysis ndi ER Stress Apoptotic Pathway.
• Gallic acid imayambitsa kuwonongeka kwa DNA ndikupondereza kukonzanso kwa DNA mu ma cell a khansa ya prostate PC-3.
• Brassinin imaletsa njira yolumikizira ya STAT3 kudzera mukusintha kwa PIAS-3 ndi SOCS-3 mawu ndikudziwitsa khansa ya m'mapapo ya anthu mu mbewa zamaliseche kupita paclitaxel.
• Vitamini C amapha ma cell a khansa ya KRAS ndi BRAF mutant colorectal cancer polunjika ku GAPDH.
• Geraniol, chigawo cha mafuta ofunikira a zomera, chimalimbikitsa maselo a khansa yamtundu wa anthu ku chithandizo cha 5-Fluorouracil.