Zakudya za Myelodysplastic Syndrome!

Introduction

Zakudya za Myelodysplastic Syndrome ziyenera kukhala zamunthu aliyense payekhapayekha komanso zimayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Myelodysplastic syndromes (MDS) ndi gulu la khansa ya m'magazi yomwe imakhudza kupanga maselo abwinobwino m'mafupa. Maselo osadziwika a leukemia akagawanika, kusintha koyambirira kumasungidwa ndipo kumapanga maselo ofanana omwe ali ndi vuto lomwelo, motero MDS ndi matenda a clonal blood stem cell disorder. Matenda a Myelodysplastic amapezeka kwambiri mwa okalamba opitilira zaka 60 ndipo amakhudza amuna pang'ono kuposa akazi. Mu MDS, maselo osadziwika bwino a m'mafupa (omwe amatchedwanso blasts) amatulutsa kuchuluka kwa maselo amagazi omwe amafa msanga. Izi zimabweretsa kuchepa kwa maselo ofiira okhwima okhwima, maselo oyera a magazi ndi mapulateleti zomwe zimapangitsa kuti wodwalayo atengeke mosavuta ndi matenda, kutuluka magazi, mikwingwirima ndi kutopa. MDS imayikidwa molingana ndi mtundu ndi kuchuluka kwa kuphulika kwa mafupa mumagulu akuluakulu a 5: refractory anemia; refractory anemia ndi sideroblasts; refractory anemia ndi kuphulika owonjezera; refractory anemia ndi kuphulika owonjezera mu kusintha; ndi matenda a myelomonocytic leukemia (CMML). Anthu omwe ali ndi MDS amakhala ndi mafupa amphamvu koma maselo a magazi amakhala ochepa kwambiri. Zizindikiro zodziwika bwino za MDS zimaphatikizapo kutopa, chizungulire, kufooka, mikwingwirima ndi kutuluka magazi, matenda obwera pafupipafupi, komanso mutu. Nthawi zina, MDS ikhoza kupita patsogolo mpaka kulephera kwa mafupa a mafupa kapena kukhala acute myeloid leukemia (AML). Njira zochizira matenda a myelodysplastic syndromes zimaphatikizapo kuikidwa magazi, zinthu zomwe zikukulirakulira monga granulocyte-colony stimulation growth factor (G-CSF), hypomethylating agents, immunomodulatory agents, ndi chemotherapy. Kuonjezera apo, chithandizo chothandizira ndi zakudya zoyenera (zakudya ndi zowonjezera zachilengedwe) zingathandize kusintha umoyo wa odwala.

Kwa Myelodysplastic Syndrome, kodi zilibe kanthu zomwe masamba, zipatso, mtedza, mbewu zimadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Myelodysplastic Syndrome kodi zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa ngati Myelodysplastic Syndrome?

Mwachitsanzo, kodi zilibe kanthu ngati Gourde wa masamba amadyedwa kwambiri poyerekeza ndi White Kabichi? Kodi zimapanga kusiyana kulikonse ngati Pummelo imakondedwa kuposa Red Raspberry? Komanso ngati kusankha kofananako kumapangidwira mtedza/mbewu monga Hazelnut pa European Chestnut ndi pulse ngati Adzuki Bean over Green Bean. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ndi Myelodysplastic Syndrome ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha chibadwa?

Inde! Zakudya zomwe mumadya ndizofunikira pa Myelodysplastic Syndrome!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Pummelo ili ndi zinthu zogwira ntchito Apigenin, Curcumin, Quercetin, Isoliquiritigenin, Lupeol. Ndipo Rasipiberi Wofiira ali ndi zosakaniza zomwe zimagwira ntchito monga Curcumin, Quercetin, Isoliquiritigenin, Ellagic Acid, Lupeol ndi ena.

Cholakwika chofala chomwe chimapangidwa posankha ndikusankha zakudya zoyenera kudya za Myelodysplastic Syndrome - ndikuwunika zomwe zasankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Myelodysplastic Syndrome.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonda Chakudya Chake kwa Myelodysplastic Syndrome?

Zakudya zamakhansa monga Myelodysplastic Syndrome zimakhala ndi zakudya zovomerezeka / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zikulimbikitsidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Myelodysplastic Syndrome biology, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zina zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa monga Myelodysplastic Syndrome

Makhansa onse monga Myelodysplastic Syndrome amatha kudziwika ndi njira yapadera ya biochemical - njira zosainira za Myelodysplastic Syndrome. Njira zama biochemical monga Amino Acid Metabolism, Histone/Protein Acetylation, RUNX Signaling, RAS-RAF Signaling ndi gawo la tanthauzo la siginecha ya Myelodysplastic Syndrome. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza pa Myelodysplastic Syndrome chiyenera kuzindikirika ndi ma signature a biochemical omwe amalumikizana nawo kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa kwa Myelodysplastic Syndrome mukamamwa mankhwala a khansa Lenalidomide, ndipo zakudya zina ndi zowonjezera sizimavomerezeka.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

RUNX1, NSD1, JAK2, KMT2A ndi EP300 ndi majini omwe ali pamwamba pa Myelodysplastic Syndrome. RUNX1 imanenedwa mu 16.1 % ya odwala oyimira m'mayesero onse azachipatala. Ndipo NSD1 imanenedwa mu 6.7%. Deta yophatikizidwa ya odwala imaphimba zaka kuyambira 24 mpaka 86. 58.6 % ya deta ya odwala amadziwika kuti ndi amuna. The Myelodysplastic Syndrome biology pamodzi ndi ma genetics omwe adanenedwa palimodzi amatanthauzira kuchuluka kwa anthu omwe amayimira njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Zakudya ndi Zowonjezera za Myelodysplastic Syndrome

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani Masamba a WAX GOURD kapena WHITE KABIJI?

Sera ya Wax Gourd ili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Isoliquiritigenin, Luteolin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, Hypoxia, P53 Signaling ndi MYC Signaling ndi ena. Sera ya Gourd imalimbikitsidwa pa Myelodysplastic Syndrome pamene chithandizo cha khansa chopitirira ndi Lenalidomide. Izi zili choncho chifukwa Sera Gourd imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Lenalidomide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba White Kabichi ndi Curcumin, Quercetin, Isoliquiritigenin, Lupeol, Kaempferol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi ena. Kabichi Yoyera ndi osavomerezeka kwa Myelodysplastic Syndrome pamene chithandizo cha khansa chikupitirirabe ndi Lenalidomide chifukwa chimasintha njira zamoyo zomwe zimapangitsa kuti chithandizo cha khansa zisagwidwe kapena kusamvera.

MALO OGWIRITSA NTCHITO MASABATA AMAPHUNZITSIDWA PA KABIJI WOYERA PA MFUNDO YA Myelodysplastic Syndrome NDI MANKHWALA A Lenalidomide.

Sankhani Chipatso RED RASPBERRY kapena PUMMELO?

Chipatso Chofiira Rasipiberi chili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Quercetin, Isoliquiritigenin, Ellagic Acid, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, Hypoxia, P53 Signaling ndi MYC Signaling ndi ena. Red Rasipiberi akulimbikitsidwa Myelodysplastic Syndrome pamene akupitilira chithandizo cha khansa Lenalidomide. Izi ndichifukwa choti Red Rasipiberi amasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Lenalidomide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu chipatso Pummelo ndi Apigenin, Curcumin, Quercetin, Isoliquiritigenin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi ena. Pummelo sivomerezedwa kwa Myelodysplastic Syndrome pamene chithandizo cha khansa chikupitirirabe ndi Lenalidomide chifukwa chimasintha njira zamoyo zomwe zimapangitsa kuti chithandizo cha khansa zisagwidwe kapena kusamvera.

CHIPATSO CHOFIIRA RASPBERRY AMAKONZEDWA PA PUMMELO KWA Myelodysplastic Syndrome NDI MANKHWALA A Lenalidomide.

Sankhani Nut HAZELNUT kapena EUROPEAN CHESTNUT?

Hazelnut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Isoliquiritigenin, Luteolin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, Histone/Protein Acetylation, P53 Signaling ndi Hypoxia ndi ena. Hazelnut akulimbikitsidwa Myelodysplastic Syndrome pamene chithandizo cha khansa chopitirira ndi Lenalidomide. Izi ndichifukwa choti hazelnut imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Lenalidomide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Apigenin, Curcumin, Quercetin, Isoliquiritigenin, Ellagic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi ena. European Chestnut ndi yosavomerezeka kwa Myelodysplastic Syndrome pamene chithandizo cha khansa chikupitirirabe ndi Lenalidomide chifukwa chimasintha njira zamoyo zomwe zimapangitsa kuti chithandizo cha khansa zisagwidwe kapena kuti chisamayankhe.

HAZELNUT AMAKONZEDWA PA CHESTNUT YA KU ULAYA PA NTCHITO YA Myelodysplastic Syndrome NDI MANKHWALA A Lenalidomide.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha chibadwa cha Myelodysplastic Syndrome kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zisankho zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani masamba YELLOW ZUCCHINI kapena SWEDE?

Zukini Zamasamba Zamasamba zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga TGFB Signaling, Histone/Protein Acetylation, Cell Cycle Checkpoints ndi MYC Signaling ndi ena. Yellow Zukini akulimbikitsidwa pangozi ya Myelodysplastic Syndrome pamene chiopsezo chokhudzana ndi majini ndi EP300. Izi ndichifukwa choti Yellow Zukini imawonjezera njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Swede ndi Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga TGFB Signaling ndi ena. Swede savomerezedwa ngati chiopsezo cha Myelodysplastic Syndrome pamene chiwopsezo chokhudzana ndi majini ndi EP300 chifukwa chimawonjezera masiginecha ake.

ZUCCHINI WA MASAMBA WA YELLOW AKUKONZEDWA PA SWEDE PA EP300 GENETIC RISK OF CANCER.

Sankhani Chipatso SOUR CHERRY kapena JUJUBE?

Chipatso Chowawasa Cherry chili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga TGFB Signaling, Histone/Protein Acetylation, PI3K-AKT-MTOR Signaling ndi MYC Signaling ndi ena. Sour Cherry akulimbikitsidwa kuti atenge chiopsezo cha Myelodysplastic Syndrome pamene chiopsezo cha majini ndi EP300. Izi ndichifukwa choti Sour Cherry imawonjezera njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu zipatso za Jujube ndi Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga TGFB Signaling, PI3K-AKT-MTOR Signaling ndi Cell Cycle Checkpoints ndi ena. Jujube sivomerezedwa ngati chiopsezo cha Myelodysplastic Syndrome pamene chiwopsezo chokhudzana ndi majini ndi EP300 chifukwa chimawonjezera masiginecha ake.

FRUIT SOUR CHERRY AMAKONZEDWA PA JUJUBE PA EP300 GENETIC RISK OF CANCER.

Sankhani Nut BUTTERNUT kapena CHESTNUT?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga TGFB Signaling, Histone/Protein Acetylation, Cell Cycle Checkpoints ndi MYC Signaling ndi ena. Butternut amalangizidwa pa chiopsezo cha Myelodysplastic Syndrome pamene chiopsezo chokhudzana ndi majini ndi EP300. Izi ndichifukwa choti Butternut imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Chestnut ndi Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga TGFB Signaling ndi Cell Cycle Checkpoints ndi ena. Chestnut sivomerezedwa ngati chiopsezo cha Myelodysplastic Syndrome pamene chiwopsezo chokhudzana ndi majini ndi EP300 chifukwa chimawonjezera masiginecha ake.

BUTTERNUT AMADALITSIDWA PA CHESTNUT PA EP300 GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndi zosankha zofunika pa khansa monga Myelodysplastic Syndrome. Odwala a Myelodysplastic Syndrome ndi anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Myelodysplastic Syndrome, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Sera Gourd chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa malingaliro onse poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha Myelodysplastic Syndrome?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Mds Mskcc 2020
• Kupewa kwa butyric acid, nicotinamide, calcium glucarate yokha kapena kuphatikiza pa 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kudzera modulation of K-Ras-PI3K-AKTpathway and related micro RNAs.
• Formononetin imachepetsa kuchulukira kwa khansa ya m'mapapo ya anthu yomwe si yaing'ono ya m'mapapo kudzera pakuphatikizidwa kwa kumangidwa kwa ma cell ndi apoptosis.
• Melatonin ndi vitamini D3 synergistically down-regulate Akt ndi MDM2 kutsogolera ku TGFβ-1-odalira kukula kulepheretsa maselo a khansa ya m'mawere.
• In vitro ndi mu vivo antitumor ntchito ya neochlorogenic acid m'maselo a m'mimba mwa munthu amaphatikizidwa ndi ROS generation, kutaya mphamvu ya mitochondrial membrane ndi apoptosis induction.
• lipidomics yogwira ntchito: Palmitic acid imalepheretsa kukula kwa hepatocellular carcinoma mwa kuwongolera kutulutsa kwa membrane ndi kagayidwe ka glucose.
• https://rarediseases.org/rare-diseases/myelodysplastic-syndromes/#:~:text=General%20symptoms%20associated%20with%20MDS,or%20develop%20into%20acute%20leukemia.
• https://www.leukaemia.org.au/blood-cancer-information/types-of-blood-cancer/myelodysplastic-syndromes
• https://www.ncbi.nlm.nih.gov/books/NBK534126