Zakudya Za Khansa Ya Mabere Amuna!

Introduction

Zakudya za Khansa ya M'mawere Amuna ziyenera kukhala zamunthu aliyense payekhapayekha komanso zimayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Kwa Amuna Khansa ya M'mawere Kodi zilibe kanthu zomwe munthu amadya zamasamba, zipatso, mtedza, mbewu?

Funso lodziwika bwino lazakudya lomwe odwala omwe ali ndi khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Male Breast Cancer, kodi zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira pa khansa ngati Male Breast Cancer?

Mwachitsanzo, kodi zilibe kanthu ngati masamba a Kabichi amadyedwa kwambiri poyerekeza ndi Broccoli? Kodi pamakhala kusiyana kulikonse ngati zipatso za Grapefruit zimakondedwa kuposa Cranberry waku Europe? Komanso ngati kusankha kofananako kumapangidwira mtedza/mbewu monga Butternut pa European Chestnut ndi zokometsera ngati Nsonga wamaso akuda pa Lima Bean. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa kwa Khansa ya M'mawere Amuna ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha chibadwa?

Inde! Zakudya zomwe mumadya ndizofunikira kwa Khansa ya M'mawere Yamuna!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo, Grapefruit imakhala ndi zinthu zogwira ntchito Catechol, Delphinidin, Hesperetin, Curcumin, Formononetin. Ndipo Cranberry ya ku Ulaya imakhala ndi zinthu zomwe zimagwira ntchito monga Quercetin, Ellagic Acid, Catechol, Apigenin, Delphinidin ndi ena.

Kulakwitsa kofala komwe kumachitika posankha ndikusankha zakudya zoyenera kudya za Khansa ya M'mawere Amuna - ndikuwunika zosankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya za Khansa ya M'mawere Amuna.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakusankha Chakudya Chake cha Khansa Yam'mawere Yamwamuna?

Zakudya zokometsera zamakhansa ngati Khansa ya M'mawere Yamuna imakhala ndi zakudya / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zimalangizidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Biology ya Khansa ya M'mawere Amuna, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zomwe mankhwalawo angasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa ngati Male Breast Cancer

Makhansa onse monga Khansa ya M'mawere Amuna amatha kudziwika ndi njira zapadera za biochemical - njira zosainira za Khansa ya M'mawere Amuna. Njira zama biochemical monga RAS-RAF Signaling, Growth Factor Signaling, PI3K-AKT-MTOR Signaling, MAPK Signaling ndi gawo la tanthauzo la siginecha ya Male Breast Cancer. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Mankhwala omwe ali othandiza kwa Khansa ya M'mawere Amuna akuyenera kudziwa njira zomwe zimagwirizana ndizomwe zimachitika kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa kwa Khansa ya M'mawere Amuna akamamwa chithandizo cha khansa ya Trastuzumab, ndipo zakudya zina ndi zowonjezera sizimavomerezedwa.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

PIK3CA, GATA3, SPEN, MAP3K1 ndi TP53 ndi omwe ali pamwamba pa chibadwa cha khansa ya m'mawere ya Amuna. PIK3CA imanenedwa mu 20.3% ya odwala oyimira m'mayesero onse azachipatala. Ndipo GATA3 idanenedwa mu 15.3%. Deta yophatikizidwa ya odwala imakhudza zaka kuyambira mpaka . % ya deta ya odwala amadziwika kuti ndi amuna. Biology ya Khansa ya M'mawere Amuna pamodzi ndi ma genetics omwe amafotokozedwa palimodzi amatanthauzira kuchuluka kwazomwe zimayimiridwa ndi njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Zakudya ndi Zowonjezera za Khansa ya M'mawere Amuna

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani Kabichi Wamasamba kapena BROCCOLI?

Kabichi wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Quercetin, Catechol, Apigenin, Delphinidin, Curcumin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, Adherens junction, Inositol Phosphate Signaling ndi MYC Signaling ndi ena. Kabichi amavomerezedwa ku Khansa ya M'mawere Amuna pamene chithandizo cha khansa nthawi zonse ndi Trastuzumab. Izi zili choncho chifukwa Kabichi amasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Trastuzumab.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Broccoli ndi Quercetin, Resveratrol, Catechol, Delphinidin, Curcumin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga TGFB Signaling ndi Extracellular Matrix Remodeling ndi ena. Broccoli ndiyosavomerezeka kwa Khansa ya M'mawere Amuna pamene chithandizo cha khansa chikupitilira Trastuzumab chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

KABIJI WA MASAMBA NDI AMAKONDWEredwa PA BROCCOLI YA Khansa Ya Mabere Amuna NDI Mchiritso Trastuzumab.

Sankhani Chipatso EUROPEAN CRANBERRY kapena GRAPEFRUIT?

Zipatso za Cranberry za ku Ulaya zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Quercetin, Ellagic Acid, Catechol, Apigenin, Delphinidin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, RAS-RAF Signaling, Adherens junction ndi PI3K-AKT-MTOR Signaling ndi ena. Cranberry yaku Europe imalimbikitsidwa kwa Khansa ya M'mawere Yamuna pomwe chithandizo cha khansa chopitilira ndi Trastuzumab. Izi zili choncho chifukwa European Cranberry imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Trastuzumab.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu zipatso za Grapefruit ndi Catechol, Delphinidin, Hesperetin, Curcumin, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga WNT Beta Catenin Signaling ndi ena. Grapefruit ndi yosavomerezeka kwa Khansa ya M'mawere Amuna pamene chithandizo cha khansa chikupitirirabe ndi Trastuzumab chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisagwirizane kapena chisamayankhe.

CRANBERRY YA ZIPATSO YA KU ULAYA IKUKONZEDWA PAMBUYE KUPANDA KHUMUDWE KWA Amuna Amuna Khansa Ya Mabere NDI MACHIRETO Trastuzumab.

Sankhani Nut BUTTERNUT kapena EUROPEAN CHESTNUT?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Catechol, Apigenin, Delphinidin, Curcumin, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, Hypoxia, RAS-RAF Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Butternut amavomerezedwa ku Khansa ya M'mawere Amuna pamene chithandizo cha khansa nthawi zonse ndi Trastuzumab. Izi zili choncho chifukwa Butternut imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Trastuzumab.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Quercetin, Ellagic Acid, Catechol, Apigenin, Delphinidin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga WNT Beta Catenin Signaling, TGFB Signaling, Epithelial to Mesenchymal Transition ndi PI3K-AKT-MTOR Signaling ndi ena. European Chestnut ndiyosavomerezeka ku Khansa ya M'mawere Amuna pomwe chithandizo cha khansa chikupitilira Trastuzumab chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

BUTTERNUT AMADALITSIDWA PA CHESTNUT YA KU ULAYA KWA Amuna A Khansa Yam'mawere NDIPO MANKHWALA A Trastuzumab.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo chotenga khansa ya m'mawere ya abambo kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani masamba WILD CARROT kapena PRAIRIE TURNIP?

Karoti Wakutchire Wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Quercetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle Checkpoints, Angiogenesis, MAPK Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Wild Carrot amalangizidwa pa chiopsezo cha khansa ya m'mawere ya abambo pamene chiopsezo chokhudzana ndi majini ndi GATA3. Izi ndichifukwa choti Wild Carrot imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Prairie Turnip ndi Apigenin, Curcumin, Lupeol, Daidzein, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Ma cell Cycle Checkpoints, Kukonza DNA ndi Kuwonetsa Insulin ndi ena. Prairie Turnip sivomerezedwa ngati chiopsezo cha khansa ya m'mawere ya abambo pamene chiwopsezo chokhudzana ndi majini ndi GATA3 chifukwa chimawonjezera ma signature njira zake.

KAROTI WAKUMALO WA ZAMALOMU AKUKONZEDWA PA PRAIRIE TURNIP PA GATA3 GENETIC RISK WA KANSA.

Sankhani Chipatso NANCE kapena PUMMELO?

Zipatso za Nance zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Daidzein, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, MYC Signaling, Angiogenesis ndi PI3K-AKT-MTOR Signaling ndi ena. Nance akulimbikitsidwa pa chiopsezo cha khansa ya m'mawere ya abambo pamene chiopsezo cha chibadwa ndi GATA3. Izi ndichifukwa choti Nance amawonjezera njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Pummelo ndi Apigenin, Curcumin, Quercetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Ma cell Cycle Checkpoints, Kukonza DNA ndi Kuwonetsa Insulin ndi ena. Pummelo sivomerezedwa ngati chiopsezo cha Khansa ya M'mawere ya Amuna pamene chiwopsezo chokhudzana ndi majini ndi GATA3 chifukwa chimawonjezera masiginecha ake.

FRUIT NANCE AKUKONZEDWA PA PUMMELO PA GATA3 GENETIC RISK OF CANCER.

Sankhani Nut COMMON WALNUT kapena FLEXSEED?

Walnut wamba amakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Quercetin, Ellagic Acid, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, Insulin Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Walnut wamba amalimbikitsidwa pa chiopsezo cha khansa ya m'mawere ya abambo pamene chiopsezo chokhudzana ndi majini ndi GATA3. Izi ndichifukwa choti Common Walnut imawonjezera njira zama biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Flaxseed ndi Apigenin, Curcumin, Lupeol, Daidzein, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, Insulin Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Flaxseed sivomerezedwa ngati chiopsezo cha Khansa ya M'mawere ya Amuna ngati chiwopsezo chokhudzana ndi majini ndi GATA3 chifukwa chimawonjezera masiginecha ake.

WALNUT WAMWAMBA AMAKONZEDWA PA FLEXSEED PA GATA3 GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndi zosankha zofunika pa khansa monga Khansa ya M'mawere Yamuna. Odwala a Khansa ya M'mawere Amuna ndi anthu omwe ali pachiwopsezo cha chibadwa nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Khansa ya M'mawere Amuna, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Kabichi chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

The addon nutrition personalization solution imapangitsa kuti zisankho zikhale zosavuta ndikuchotsa zongopeka poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha kwa Khansa ya Mabere Amuna?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Daidzein imakhudzanso khansa ya prostate ya refractory mu vitro komanso mu vivo poyerekeza ndi genistein ndi soya: kuthekera kwa radiotherapy.
• Chemoprevention of intestinal tumorigenesis ndi chilengedwe cha flavonoid myricetin mu APCMin/+ mbewa.
• Kupewa kwa butyric acid, nicotinamide, calcium glucarate yokha kapena kuphatikiza pa 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kudzera modulation of K-Ras-PI3K-AKTpathway and related micro RNAs.
• Kuwongolera koyipa kwa transducer ya ma signal ndi activator ya transcript-3 signing cascade ndi lupeol imalepheretsa kukula ndikupangitsa apoptosis mu cell hepatocellular carcinoma.
• Zotsatira za antitumor za geraniol: Kusinthasintha kwa njira zodziwika ndi khansa (Kubwereza).
• Malingaliro atsopano mu phospholipase D chizindikiro mu kutupa ndi khansa.