Zakudya za Hemangiopericytoma!

Introduction

Zakudya za Hemangiopericytoma ziyenera kukhala zamunthu aliyense payekhapayekha komanso ziyenera kusinthidwa ndi chithandizo cha khansa kapena kusintha kwa chibadwa cha chotupa. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Hemangiopericytoma, yomwe imadziwikanso kuti yokhayokha ya fibrous chotupa, ndi khansa yachilendo yomwe imachokera ku maselo ozungulira mitsempha ya magazi otchedwa pericytes. Kulemba kolondola kwachipatala pogwiritsa ntchito kachidindo koyenera ka ICD-10 ndikofunikira pakulemba. Radiology imagwira ntchito yofunika kwambiri pakuwunika ndikuwunika kwa hemangiopericytoma, kupereka chidziwitso chofunikira pamikhalidwe yake komanso malo ake. Zolemba za pathology zimapereka chidziwitso chofunikira chokhudza ma cell a hemangiopericytoma. Hemangiopericytoma ingakhudze mbali zosiyanasiyana za thupi, kuphatikizapo ubongo, chiwindi, ndi diso. Chithandizo cha hemangiopericytoma nthawi zambiri chimaphatikizapo opaleshoni, chithandizo cha radiation, ndipo nthawi zina mankhwala amphamvu, malingana ndi vuto linalake. Kupulumuka ndi momwe hemangiopericytoma imakhalira zimasiyana malinga ndi zinthu monga chotupa ndi malo. Kudziwitsa komanso kutsatira malangizo azachipatala ndikofunikira kuti pakhale zotsatira zabwino kwa odwala omwe ali ndi hemangiopericytoma. Pofunafuna chithandizo choyenera cha Chowona Zanyama cha hemangiopericytoma mwa agalu, eni ake amatha kupititsa patsogolo mwayi wa ziweto zawo kuti zitheke bwino ndikukulitsa moyo wawo.

Kwa Hemangiopericytoma, kodi zimakhala ndi masamba, zipatso, mtedza, mbewu zomwe munthu amadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - kwa khansa monga Hemangiopericytoma kodi zilibe kanthu kuti ndikudya chiyani komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa monga Hemangiopericytoma?

Mwachitsanzo, kodi zilibe kanthu ngati masamba a Orange Bell adyedwa kwambiri poyerekeza ndi Daikon Radish? Kodi zimapanga kusiyana kulikonse ngati chipatso Pummelo chimakondedwa kuposa Java Plum? Komanso ngati kusankha kofananako kumapangidwira mtedza/mbewu monga Chia pa Mtedza wa Cashew ndi zamasamba monga White Lupine pa Yardlong Bean. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ku Hemangiopericytoma ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha chibadwa?

Inde! Zakudya zomwe mumadya ndizofunikira pa Hemangiopericytoma!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Pummelo ili ndi zosakaniza zogwira ntchito Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. Ndipo Java Plum ili ndi zosakaniza zomwe zimagwira Apigenin, Curcumin, Daidzein, Lycopene, Lupeol ndi ena.

Cholakwika chofala chomwe chimapangidwa posankha ndikusankha zakudya zoyenera kudya za Hemangiopericytoma - ndikuwunika zosankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina zonse. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza zomwe zimagwira ntchito muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Hemangiopericytoma.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonda Chakudya Mwamakonda a Hemangiopericytoma?

Zakudya zamakhansa monga Hemangiopericytoma zimakhala ndi zakudya / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zikulimbikitsidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Hemangiopericytoma biology, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zina zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa monga Hemangiopericytoma

Makhansa onse monga Hemangiopericytoma amatha kudziwika ndi njira yapadera ya biochemical pathways - signature pathways of Hemangiopericytoma. Njira zama biochemical monga PI3K-AKT-MTOR Signaling, TGFB Signaling, Apoptosis, Cell Cycle Checkpoints ndi gawo la tanthauzo la Hemangiopericytoma. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza pa Hemangiopericytoma chikuyenera kuzindikirika ndi njira zomwe zimagwirizana ndizomwe zimachitika kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa kwa Hemangiopericytoma mukamamwa mankhwala a khansa a Topotecan, ndipo zakudya zina ndi zowonjezera sizovomerezeka.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

TERT, TP53, BCOR, BTK ndi KDM5C ndi omwe ali pamwamba pa jini za Hemangiopericytoma. TERT imanenedwa mu 46.2% ya odwala oyimira m'mayesero onse azachipatala. Ndipo TP53 idanenedwa mu 30.8%. Deta yophatikizidwa ya odwala imakhudza zaka kuyambira mpaka . 48.7 % ya data ya odwala amadziwika kuti ndi amuna. Hemangiopericytoma biology pamodzi ndi ma genetics omwe adanenedwa palimodzi amatanthauzira kuchuluka kwa anthu omwe amayimira njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Zakudya ndi Zowonjezera za Hemangiopericytoma

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani Masamba ORANGE BELL PEPPER kapena DAIKON RADISH

Masamba a Orange Bell Tsabola ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga NFKB Signaling, MYC Signaling, TGFB Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Tsabola wa Orange Bell akulimbikitsidwa kwa Hemangiopericytoma pamene chithandizo cha khansa chikupitirirabe ndi Topotecan. Izi ndichifukwa choti Tsabola ya Orange Bell imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Topotecan.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Daikon Radish ndi Apigenin, Curcumin, Daidzein, Lupeol, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga TGFB Signaling ndi NFKB Signaling ndi ena. Daikon Radish sizovomerezeka kwa Hemangiopericytoma pamene chithandizo cha khansa chikupitirirabe ndi Topotecan chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena chisamayankhe.

PILIPULA WA MANKHWALA WA MANKHWALA AMAKONZEDWA PA DAIKON RADISH KWA Hemangiopericytoma NDI MANKHWALA A Topotecan.

Sankhani Chipatso JAVA PLUM kapena PUMMELO

Chipatso Java Plum chili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Apoptosis, MYC Signaling, NFKB Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Java Plum ikulimbikitsidwa kwa Hemangiopericytoma pamene chithandizo cha khansa chikupitirirabe ndi Topotecan. Izi ndichifukwa choti Java Plum imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse za Topotecan.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Pummelo ndi Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle Checkpoints ndi NFKB Signaling ndi ena. Pummelo sivomerezedwa kwa Hemangiopericytoma pamene chithandizo cha khansa chikupitirirabe ndi Topotecan chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisagwirizane kapena chisamayankhe.

ZIPATSO JAVA PLUM AMAKONZEDWA KUPOSA PUMMELO KWA Hemangiopericytoma NDI MANKHWALA A Topotecan.

Sankhani Nut CHIA kapena CASHEW NUT

Chia ili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Daidzein, Lycopene, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Ma Cell Cycle Checkpoints, TGFB Signaling, NFKB Signaling ndi MYC Signaling ndi ena. Chia akulimbikitsidwa Hemangiopericytoma pamene chithandizo cha khansa chikupitirirabe ndi Topotecan. Izi ndichifukwa choti Chia amasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Topotecan.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Cashew Nut ndi Curcumin, Daidzein, Lupeol, Formononetin, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga NFKB Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Mtedza wa Cashew ndiwosavomerezeka kwa Hemangiopericytoma pamene chithandizo cha khansa chikupitirirabe ndi Topotecan chifukwa chimasintha njira zamoyo zomwe zimapangitsa kuti chithandizo cha khansa zisawonongeke kapena kuti chisamayankhe.

CHIA AKUNDIKONZEDWA PA MATENDA WA KASHEWU WA Hemangiopericytoma NDI Mchiritsi Topotecan.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha chibadwa cha Hemangiopericytoma kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani Masamba BURDOCK kapena BLACK KABIJI

Burdock yamasamba imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga B Cell Receptor Signaling, MYC Signaling, NFKB Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Burdock akulimbikitsidwa pachiwopsezo cha Hemangiopericytoma pomwe chiwopsezo cha chibadwa ndi BCOR. Izi ndichifukwa choti burdock imawonjezera njira zama biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu masamba a Black Kabichi ndi Curcumin, Apigenin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga NFKB Signaling ndi Oncogenic Cancer Epigenetics ndi ena. Kabichi wakuda samavomerezedwa ngati chiwopsezo cha Hemangiopericytoma chikugwirizana ndi chiopsezo cha chibadwa cha BCOR chifukwa chimawonjezera njira zake.

MALO OGWIRITSIDWA NTCHITO PA KABIJI WAKUDA PA BCOR GENETIC RISK OF CANCER.

Sankhani Chipatso HIGHBUSH BLUEBERRY kapena ACEROLA

Zipatso za Highbush Blueberry zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Quercetin, Formononetin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Ma Cell Cycle Checkpoints, Phospholipase Signaling, NFKB Signaling ndi MYC Signaling ndi ena. Highbush Blueberry imalimbikitsidwa kuti ikhale pachiwopsezo cha Hemangiopericytoma pomwe chiopsezo chogwirizana ndi chibadwa ndi BCOR. Izi ndichifukwa choti Highbush Blueberry imawonjezera njira zama biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso za Acerola ndi Curcumin, Apigenin, Quercetin, Formononetin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga NFKB Signaling ndi Oncogenic Cancer Epigenetics ndi ena. Acerola sivomerezedwa ngati chiopsezo cha Hemangiopericytoma pamene chiwopsezo cha chibadwa ndi BCOR chifukwa chimawonjezera njira zake.

ZIPATSO HIGHBUSH BLUEBERRY ZIKUKONZEDWA PA ACEROLA PA BCOR GENETIC RISK OF CANCER.

Sankhani Nut BUTTERNUT kapena EUROPEAN CHESTNUT

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Ma Cell Cycle Checkpoints, Phospholipase Signaling, NFKB Signaling ndi MYC Signaling ndi ena. Butternut amalangizidwa pachiwopsezo cha Hemangiopericytoma ngati chiwopsezo cha chibadwa ndi BCOR. Izi ndichifukwa choti Butternut imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Curcumin, Apigenin, Quercetin, Formononetin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle Checkpoints, Oncogenic Cancer Epigenetics ndi Stem Cell Signaling ndi ena. European Chestnut sivomerezedwa ngati chiopsezo cha Hemangiopericytoma pamene chiwopsezo cha chibadwa ndi BCOR chifukwa chimawonjezera njira zake.

BUTTERNUT AMAKANGALALA PA CHESTNUT YA KU ULAYA PA BCOR GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zosankhidwa ndizofunika kwambiri pa khansa monga Hemangiopericytoma. Odwala a Hemangiopericytoma ndi anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana ya zowonetsa za khansa monga Hemangiopericytoma, iliyonse ili ndi ma genetic chotupa chosiyana ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Orange Bell Tsabola chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

The addon nutrition personalization solution imapangitsa kupanga zisankho kukhala kosavuta ndikuchotsa zongopeka poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha Hemangiopericytoma?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Msk Impact 2017
• Mawonekedwe osinthika a khansa ya metastatic adawululidwa kuchokera kwa odwala 10,000 omwe akuyembekezeka.
• Melatonin ndi vitamini D3 synergistically down-regulate Akt ndi MDM2 kutsogolera ku TGFβ-1-odalira kukula kulepheretsa maselo a khansa ya m'mawere.
• (+) -Catechin imalepheretsa chotupa angiogenesis ndikuwongolera kupanga nitric oxide ndi TNF-alpha mu LPS-stimulated macrophages.
• Chlorogenic acid imalepheretsa kuchulukana ndipo imapangitsa apoptosis m'maselo a khansa ya impso ya anthu A498 kudzera mu inactivating PI3K/Akt/mTOR njira yolumikizira.
• Wang K et al, Biomed Res Int., 2020, DOI: 10.1155/2020/2468320; Huang L et al, Front. Oncol., 2021
• https://doi.org/10.3389/fonc.2021.577054