Ndi khansa iti yomwe ingapindule ndikuphatikiza Vitamini B3 muzakudya zawo?

Mfundo

Vitamini B3 amadziwika kwambiri chifukwa cha thanzi lake ndipo amagwiritsidwa ntchito kawirikawiri ndi odwala khansa komanso omwe ali pachiopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Vitamini B3 kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, chithandizo china, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zingakhudze zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, Vitamini B3 ikhoza kupindulitsa iwo omwe ali ndi matenda a Primary Richter omwe akudwala Doxorubicin, koma sizingakhale zabwino kwa odwala omwe akulandira Mitomycin ya Primary Penile Squamous Cell Carcinoma. Kuphatikiza apo, ngakhale Vitamini B3 ikhoza kuthandiza anthu omwe ali ndi chiwopsezo chamtundu wa "ERCC2", sizingaganizidwe kwa omwe ali ndi chiwopsezo chosiyana cha "ALK". Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Vitamini B3 kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Vitamini B3 ndiye chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Popeza zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zotsatira zonse zomwe zimagwira ntchito muzakudya / zowonjezera monga Vitamini B3 m'malo mowunika chilichonse chomwe chimagwira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lofunika kwambiri likubuka: Kodi muyenera kuphatikiza Vitamini B3 muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndi bwino kudya Vitamini B3 ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya ERCC2? Bwanji ngati m'malo mwake chiopsezo chanu cha chibadwa chimachokera ku jini ya ALK? Kodi ndizopindulitsa kuphatikiza Vitamini B3 muzakudya zanu ngati mwapezeka ndi Primary Penile Squamous Cell Carcinoma, kapena ngati matenda anu ndi Primary Richter syndrome? Komanso, kodi kadyedwe kanu ka Vitamini B3 kuyenera kusinthidwa bwanji ngati mukulandira chithandizo cha Doxorubicin kapena ngati dongosolo lanu lamankhwala likuchoka ku Doxorubicin kupita ku Mitomycin? Ndikofunikira kuzindikira kuti zonena zosavuta monga 'Vitamini B3 ndi zachilengedwe, choncho zimakhala zopindulitsa nthawi zonse' kapena 'Vitamini B3 imalimbitsa chitetezo cha mthupi' ndizosakwanira kusankha zakudya/zowonjezera zowonjezera.

Kuphatikiza apo, ndikofunikira kuunikanso kuyenera kwa kuphatikiza Vitamini B3 muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Vitamini B3 muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira zachilengedwe chonse chazinthu zonse, poganizira zinthu monga mtundu wa khansa, machiritso omwe mukukumana nawo, majini. mayendedwe, ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Akapezeka ndi mtundu wina wa khansa, monga Primary Richter syndrome kapena Primary Penile Squamous Cell Carcinoma, njira zothandizira ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthu, siteji ya matendawa, komanso zinthu monga zaka ndi jenda.

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndilakuti mungakhale ndi chiwopsezo cha majini ndi matenda enaake a khansa posankha zakudya, monga Vitamini B3. Kodi chiwopsezo cha chibadwa cha khansa yobwera chifukwa cha kusintha kwa ERCC2 chimakhala ndi njira yofananira ndi kusintha kwa ALK? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Richter syndrome chikufanana ndi Primary Penile Squamous Cell Carcinoma? Kuonjezera apo, kodi kulingalira kwa zakudya kumakhalabe komweko kwa omwe amalandira Mitomycin monga omwe amalandira Doxorubicin? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Vitamini B3 - Chowonjezera Chakudya

Vitamini B3 yowonjezera imaphatikizapo zinthu zosiyanasiyana zogwira ntchito, kuphatikizapo Vitamini B3, zomwe zimapezeka mosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka kukonza kwa DNA, PI3K-AKT-MTOR Signaling ndi Angiogenesis, zomwe zimayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zakudya zoyenera monga Vitamini B3, kokha kapena kuphatikiza, kumakhala chisankho chofunikira kwambiri pazakudya za khansa. Poganizira kugwiritsa ntchito Vitamini B3 pa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Vitamini B3 si chisankho chapadziko lonse choyenera makhansa onse koma chiyenera kukhala chamunthu.

Kusankha Vitamini B3 Zowonjezera

Kuyankha funso loti 'Ndiyenera kupewa liti Vitamini B3 munkhani ya Khansa' ndizovuta chifukwa yankho limakhala la munthu payekhapayekha - zimangotengera 'zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Vitamini B3 zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu weniweni wa khansa, chibadwa, chithandizo chamakono, zowonjezera zowonjezera zomwe zikumwedwa, zizoloŵezi za moyo, BMI, ndi ziwengo zilizonse zimathandizira kudziwa ngati Vitamini B3 ndi yoyenera kapena iyenera kupeŵedwa, kutsindika kufunika koganizira zaumwini. muzosankha zotero.

1. Kodi Vitamini B3 Zowonjezera Zingapindule Odwala Odwala Odwala Omwe Akulandira Mitomycin?

Primary Penile Squamous Cell Carcinoma imadziwika ndi kusintha kwa majini, komwe ndi ABRAXAS1, PIK3CB ndi NUP93, zomwe zimabweretsa kusintha kwa njira zama biochemical, makamaka PI3K-AKT-MTOR Signaling, Hematopoiesis ndi Inositol Phosphate Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Mitomycin, kumadalira momwe amachitira panjira izi. Njira yoyenera imaphatikizapo kugwirizanitsa machitidwe a chithandizo ndi njira zomwe zimayendetsa khansara, potero kuonetsetsa kuti munthu ali ndi njira yoyenera komanso yothandiza. Zikatero, kupewa zakudya kapena zakudya zopatsa thanzi zomwe zitha kuthana ndi zotsatira za mankhwalawa kapena kuchepetsa kusanja kumeneku ndikofunikira. Mwachitsanzo, chowonjezera cha Vitamini B3, chomwe chimakhudza PI3K-AKT-MTOR Signaling, sichingakhale chisankho choyenera pankhani ya Primary Penile Squamous Cell Carcinoma pamene mukukumana ndi Mitomycin. Izi zili choncho chifukwa zikhoza kukulitsa kukula kwa matendawa kapena kusokoneza mphamvu ya mankhwala. Posankha dongosolo lazakudya, ndikofunikira kuganizira zinthu monga mtundu wa khansa, chithandizo chopitilira, zaka, jenda, BMI, moyo, ndi masinthidwe aliwonse odziwika bwino.

2. Kodi Vitamini B3 Supplements idzathandiza Odwala omwe akulandira chithandizo cha Doxorubicin?

Primary Richter syndrome imadziwika ndi kusintha kwa majini, monga MYC, TRAF3 ndi TP53, zomwe zimabweretsa kusintha kwa njira zama biochemical, makamaka DNA Repair, Noncoding RNA Signaling, MAPK Signaling, Cytokine Signaling, Antigen Presentation, Cell Cycle Checkpoints ndi Apoptosis. Kuchita bwino kwa chithandizo cha khansa, monga Doxorubicin, kumatsimikiziridwa ndi kulumikizana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, vitamini B3 yowonjezera ndi njira yabwino kwa iwo omwe ali ndi matenda a Primary Richter omwe akudwala Doxorubicin. Izi ndichifukwa choti Vitamini B3 imakhudza njira monga DNA Repair, yomwe imatha kuletsa zomwe zimayambitsa matenda a Primary Richter kapena kupindulitsa mphamvu ya Doxorubicin.

3. Kodi Zowonjezera za Vitamini B3 Ndi Zotetezeka kwa Anthu Amene Ali ndi ALK Mutation Associated Genetic Risk?

Makampani osiyanasiyana amapereka magulu a majini kuti awone kuopsa kwa ma genetic a mitundu yosiyanasiyana ya khansa. Maguluwa amaphatikizapo majini okhudzana ndi khansa ya m'mawere, ovarian, chiberekero, prostate, ndi khansa ya m'mimba. Kuyesa majiniwa kumatha kutsimikizira matenda ndikudziwitsa njira zamankhwala ndi kasamalidwe. Kuzindikira kusiyanasiyana komwe kumayambitsa matenda kungathandizenso kuyesa ndikuzindikira achibale omwe ali pachiwopsezo. Jini la ALK nthawi zambiri limaphatikizidwa m'magulu awa pakuwunika chiopsezo cha khansa.

Kusintha kwa jini ya ALK kumakhudza njira za biochemical kapena njira, monga Angiogenesis ndi Growth Factor Signaling, zomwe zimakhudzidwa mwachindunji kapena molakwika pakuyendetsa khansa pamlingo wa maselo. Pamene gulu la majini likuwonetsa kusintha kwa ALK komwe kumakhudzana ndi chiopsezo chowonjezereka cha Central Nervous System, zomveka za sayansi zimasonyeza kupeŵa kugwiritsa ntchito vitamini B3 yowonjezera. Izi ndichifukwa choti kuwonjezera kwa Vitamini B3 kumakhudza njira ngati Angiogenesis, zomwe zimatha kubweretsa zovuta pakusintha kwa ALK ndi zina zokhudzana ndi khansa.

4. Kodi Vitamini B3 Zowonjezera Ndi Zotetezeka kwa Anthu Athanzi Amene Ali ndi ERCC2 Mutation Associated Genetic Risk?

ERCC2 imatenga gawo lofunikira pakuwunika chiopsezo cha khansa. Kusintha kwa ERCC2 kumatha kusokoneza njira zovuta zamankhwala, kuphatikiza Kukonzanso kwa DNA, komwe kumakhudza kukula kwa khansa. Ngati gulu lanu la majini likuwonetsa masinthidwe a ERCC2 okhudzana ndi Khansa Yapakhungu, ganizirani kuphatikiza zowonjezera za Vitamini B3 muzakudya zanu. Zowonjezera izi zitha kukhudza njira ngati DNA Repair, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi masinthidwe a ERCC2 ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya zopatsa thanzi, kuphatikiza zakudya ndi zowonjezera monga Vitamini B3, ndi chida chothandiza chomwe chitha kuwongoleredwa ndi inu mukukumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

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