Zakudya Za Khansa Yaing'ono Yam'mapapo!

Introduction

Zakudya Zam'mapapo Ang'onoang'ono Khansa ya m'mapapo iyenera kukhala yamunthu aliyense payekha komanso imayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Kwa Khansa Yamapapo Ang'onoang'ono Kodi zilibe kanthu zomwe munthu amadya zamasamba, zipatso, mtedza, mbewu?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Small Cell Lung Cancer Kodi zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa ngati Small Cell Lung Cancer?

Mwachitsanzo, kodi zilibe kanthu ngati Kolifulawa wamasamba amadyedwa kwambiri poyerekeza ndi Turnip? Kodi pamakhala kusiyana kulikonse ngati Pummelo amakondedwa kuposa makangaza? Komanso ngati kusankha kofananako kumapangidwa pa mtedza/mbewu monga Butternut pa Mtedza wa Cashew ndi zamasamba monga Broad Bean pa Yardlong Bean. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalangizidwa ku Khansa Yaing'ono Yam'mapapo ndipo kodi ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo chobadwa nacho?

Inde! Zakudya zomwe mumadya ndizofunikira pa Khansa Yaing'ono Yam'mapapo!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Pummelo ili ndi zinthu zogwira ntchito monga Quercetin, Curcumin, Apigenin, Lycopene, Phloretin. Ndipo makangaza ali ndi zinthu zomwe zimagwira ntchito monga Quercetin, Curcumin, Ellagic Acid, Apigenin, Myricetin ndi ena.

Kulakwitsa kofala komwe kumachitika posankha ndikusankha zakudya zodya ku Kansa Yaing'ono Yam'mapapo - ndikuwunika zomwe zasankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungasankhe zosakaniza zomwe zimagwira ntchito muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Small Cell Lung Cancer.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonza Chakudya Chake pa Khansa Yaing'ono Yam'mapapo?

Zakudya zokometsera za khansa ngati Small Cell Lung Cancer imakhala ndi zakudya zovomerezeka / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zimalangizidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Biology ya Khansa Yam'mapapo Ang'onoang'ono, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zina zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa ngati Small Cell Lung Cancer

Makhansa onse ngati Khansa Yam'mapapo Yam'mapapo imatha kudziwika ndi njira zapadera za biochemical - njira zosainira za Khansa Yaing'ono Yam'mapapo. Njira zama biochemical monga Cell Cycle, Growth Factor Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints ndi gawo la tanthauzo la Siginecha ya Small Cell Lung Cancer. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza pa Khansa Yam'mapapo Yam'mapapo Ang'onoang'ono amayenera kudziwa njira zomwe zimagwirizana ndizomwe zimachitika kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa ku Khansa Yaing'ono Yam'mapapo mukamamwa mankhwala a khansa ya Topotecan, ndipo zakudya zina ndi zowonjezera sizimalimbikitsidwa.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

TP53, RB1, RYR2, KMT2D ndi FAT3 ndi omwe ali pamwamba pa chibadwa cha khansa ya m'mapapo yaing'ono. TP53 imanenedwa mu 37.2% ya odwala oyimira m'mayesero onse azachipatala. Ndipo RB1 imanenedwa mu 27.1%. Deta yophatikizidwa ya odwala imaphimba zaka kuyambira 25 mpaka 87. 58.0 % ya data ya odwala amadziwika kuti ndi amuna. Biology ya Khansa Yam'mapapo Yam'mapapo Ang'onoang'ono pamodzi ndi ma genetics omwe adanenedwa palimodzi amatanthauzira kuchuluka kwazomwe zimayimiridwa ndi njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Chakudya ndi Zowonjezera za Khansa Yaing'ono Yam'mapapo

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani masamba a CAULIFLOWER kapena TURNIP?

Kolifulawa wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Phloretin, Lupeol, Isoliquiritigenin, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, Epithelial to Mesenchymal Transition, P53 Signaling ndi Nutrient sensing ndi ena. Kolifulawa akulimbikitsidwa ku Small Cell Lung Cancer pamene chithandizo cha khansa chikupitirirabe ndi Topotecan. Izi ndichifukwa choti Kolifulawa amasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Topotecan.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Turnip yamasamba ndi Quercetin, Curcumin, Ellagic Acid, Phloretin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, Epithelial to Mesenchymal Transition ndi WNT Beta Catenin Signaling ndi ena. Turnip ndiyosavomerezeka kwa Khansa Yaing'ono Yam'mapapo pomwe chithandizo cha khansa chikupitilira ndi Topotecan chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.

CAULIFLOWER YA MASAMBA AKUKONDWEREDWA PAFUPIFUPI KUPITA KWA KANSANSI YABWINO YA M'mapapo Aang'ono NDI MANKHWALA A Topotecan.

Sankhani Chipatso POMEGRANATE kapena PUMMELO?

Chipatso Makangaza ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Quercetin, Curcumin, Ellagic Acid, Apigenin, Myricetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, Cell Cycle, TGFB Signaling ndi Metastasis ndi ena. Makangaza akulimbikitsidwa ku Small Cell Lung Cancer pamene chithandizo cha khansa chikupitirirabe ndi Topotecan. Izi ndichifukwa choti makangaza amasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse za Topotecan.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Pummelo ndi Quercetin, Curcumin, Apigenin, Lycopene, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga DNA Repair ndi WNT Beta Catenin Signaling ndi ena. Pummelo sivomerezedwa ku Khansa Yaing'ono Yam'mapapo pamene chithandizo cha khansa chikupitirirabe ndi Topotecan chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisagwirizane kapena chisamayankhe.

KANGAZA WA CHIPATSO AMAKONZEDWA KUPOSA PUMMELO KWA Khansa Yaing'ono Yam'mapapo NDIPO MANKHWALA A Topotecan.

Sankhani Mtedza BUTTERNUT kapena MALO A KASHEW?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Myricetin, Lycopene, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza kwa DNA, Cell Cycle, P53 Signaling ndi MAPK Signaling ndi ena. Butternut akulimbikitsidwa ku Small Cell Lung Cancer pamene chithandizo cha khansa chikupitirirabe ndi Topotecan. Izi ndichifukwa choti Butternut imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Topotecan.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Cashew Nut ndi Quercetin, Curcumin, Myricetin, Phloretin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza kwa DNA, MAPK Signaling ndi MYC Signaling ndi ena. Mtedza wa Cashew ndiwosavomerezeka ku Khansa Yam'mapapo Yam'mapapo pomwe chithandizo cha khansa chikupitilira ndi Topotecan chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.

BUTTERNUT AMAKONZEDWA PA MATENDA WA KASHEW PA Khansa Yaing'ono Yam'mapapo NDIPO MANKHWALA A Topotecan.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiwopsezo cha chibadwa cha Khansa Yaing'ono Yam'mapapo kapena mbiri yabanja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani Masamba GIANT BUTTERBUR kapena ARROWROOT?

Masamba a Giant Butterbur ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, P53 Signaling, DNA Repair ndi MYC Signaling ndi ena. Giant Butterbur ikulimbikitsidwa kuti ikhale pachiwopsezo cha Kansa Yam'mapapo Yaing'ono ngati chiwopsezo cha chibadwa ndi FAT3. Izi ndichifukwa choti Giant Butterbur imakulitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Arrowroot ndi Apigenin, Curcumin, Lupeol, Daidzein, Quercetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kukonza kwa DNA, Kuwonetsa Maselo a Stem Cell Cycle Checkpoints ndi ena. Arrowroot ndi osavomerezeka pamene chiopsezo cha Small Cell Lung Cancer pamene kugwirizana chibadwa chiopsezo ndi FAT3 chifukwa kumawonjezera siginecha njira zake.

MANKHWALA WABWINO WA MASWERO AKUFUNIKA KUPOSA ARROWROOT PA FAT3 GENETIC RISK OF CANCER.

Sankhani Chipatso NANCE kapena MALUS (CRAB APPLE)?

Zipatso za Nance zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, P53 Signaling, DNA Repair ndi MYC Signaling ndi ena. Nance akulimbikitsidwa pa chiopsezo cha Small Cell Lung Cancer pamene chiopsezo chokhudzana ndi majini ndi FAT3. Izi ndichifukwa choti Nance amawonjezera njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Malus (nkhanu Apple) ndi Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kukonza kwa DNA, Kuwonetsa Maselo a Stem Cell Cycle Checkpoints ndi ena. Malus (nkhanu Apple) sivomerezedwa ngati chiopsezo cha Small Cell Lung Cancer pamene chiwopsezo chokhudzana ndi majini ndi FAT3 chifukwa chimawonjezera ma signature njira zake.

FRUIT NANCE AKUKONZEDWA PA MALUS (CRAB APPLE) PA FAT3 GENETIC RISK OF CANCER.

Sankhani Nut COMMON HAZELNUT kapena CHESTNUT?

Mtedza wamba uli ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Lupeol, Daidzein, Quercetin, Beta-sitosterol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, Cell Cycle, Angiogenesis ndi Stem Cell Signaling ndi ena. Common Hazelnut akulimbikitsidwa pa chiopsezo cha Small Cell Lung Cancer pamene chiopsezo chokhudzana ndi majini ndi FAT3. Izi ndichifukwa choti Common Hazelnut imachulukitsa njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Chestnut ndi Apigenin, Curcumin, Lupeol, Ellagic Acid, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kukonza kwa DNA, Kuwonetsa Maselo a Stem Cell Cycle Checkpoints ndi ena. Mchere wa Chestnut ndi wosavomerezeka ngati chiwopsezo cha Khansa Yaing'ono Yam'mapapo ngati chiwopsezo cha chibadwa ndi FAT3 chifukwa chimawonjezera njira zake.

HAZELNUT WAMWAMBA AMAKONZEDWA PA CHESTNUT PA FAT3 GENETIC RISK YA KANSA.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndi zosankha zofunika pa khansa monga Small Cell Lung Cancer. Odwala a khansa ya m'mapapo ang'onoang'ono komanso anthu omwe ali pachiwopsezo chotengera majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Khansa Yam'mapapo Yam'mapapo, iliyonse ili ndi ma genetic chotupa chosiyana ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Kolifulawa chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga zisankho kukhala kosavuta ndikuchotsa malingaliro onse poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha ku Khansa Yaing'ono Yam'mapapo?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Lung Msk Pdx
• Kusanthula kwa ma genome ophatikizika kumazindikiritsa masinthidwe ofunika kwambiri a khansa ya m'mapapo ang'onoang'ono.
• Kukonzekera kwa DNA ndi ntchito za redox ndi zoletsa za apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): kusanthula koyerekeza ndi kuchuluka kwawo ndi zolephera pakukula kwa mankhwala oletsa khansa.
• Betulinic acid imalepheretsa kukhazikika ndi EMT ya maselo a khansa ya pancreatic kudzera pakuyambitsa chizindikiro cha AMPK.
• Gallic acid imayambitsa kuwonongeka kwa DNA ndikupondereza kukonzanso kwa DNA mu ma cell a khansa ya prostate PC-3.
• Citrus flavonoid naringenin imathandizira kukonza DNA m'maselo a khansa ya prostate.
• Brassinin Imapondereza Kuthekera Kwa Ma cell a Lung Carcinoma Kupyolera mu Kutsekedwa kwa PI3K/Akt/mTOR Signaling Cascade.
• Kuwongolera koyipa kwa transducer ya ma signal ndi activator ya transcript-3 signing cascade ndi lupeol imalepheretsa kukula ndikupangitsa apoptosis mu cell hepatocellular carcinoma.