Zakudya za Colorectal Neuroendocrine Carcinoma!

Introduction

Zakudya za Colorectal Neuroendocrine Carcinoma ziyenera kukhala zamunthu aliyense payekhapayekha komanso ziyenera kusinthidwa ndi chithandizo cha khansa kapena kusintha kwa chibadwa cha chotupa. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Kwa Colorectal Neuroendocrine Carcinoma kodi zili ndi masamba, zipatso, mtedza, mbewu zomwe munthu amadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa monga Colorectal Neuroendocrine Carcinoma kodi zilibe kanthu kuti ndikudya chiyani komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa ngati Colorectal Neuroendocrine Carcinoma?

Mwachitsanzo, kodi zilibe kanthu ngati Tsabola wamasamba (kapsicum) amadyedwa kwambiri poyerekeza ndi Yam? Kodi zimapanga kusiyana kulikonse ngati chipatso Pummelo chimakondedwa kuposa Bayberry? Komanso ngati kusankha kofananako kumapangidwira mtedza/mbewu monga Butternut pa Hickory Nut komanso zamasamba monga White Lupine pa Lima Bean. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ku Colorectal Neuroendocrine Carcinoma ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha majini?

Inde! Zakudya zomwe mumadya ndizofunikira pa Colorectal Neuroendocrine Carcinoma!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Pummelo ili ndi zosakaniza zogwira ntchito Apigenin, Curcumin, Lupeol, Quercetin, Daidzein. Ndipo Bayberry ili ndi zosakaniza zomwe zimagwira Apigenin, Curcumin, Lupeol, Daidzein, Catechol ndi ena.

Kulakwitsa kofala komwe kumachitika posankha ndikusankha zakudya zodyera Colorectal Neuroendocrine Carcinoma - ndikuwunika zosakaniza zosankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina zonse. Chifukwa zosakaniza zosiyanasiyana zomwe zili m'zakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungasankhe zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Colorectal Neuroendocrine Carcinoma.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonda Chakudya Chake kwa Colorectal Neuroendocrine Carcinoma?

Zakudya zokometsera zamakhansa monga Colorectal Neuroendocrine Carcinoma zimakhala ndi zakudya zovomerezeka / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zikulimbikitsidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Colorectal Neuroendocrine Carcinoma biology, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zomwe zingayambitse zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa monga Colorectal Neuroendocrine Carcinoma

Makhansa onse monga Colorectal Neuroendocrine Carcinoma amatha kudziwika ndi njira zapadera za biochemical - njira zosayina za Colorectal Neuroendocrine Carcinoma. Njira zama biochemical monga Cell Cycle, MAPK Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints ndi gawo la tanthauzo la Colorectal Neuroendocrine Carcinoma. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza kwa Colorectal Neuroendocrine Carcinoma chiyenera kuzindikirika ndi ma signature a biochemical pathology kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa ku Colorectal Neuroendocrine Carcinoma mukamamwa mankhwala a khansa a Lanreotide, ndipo zakudya zina ndi zowonjezera sizimalimbikitsidwa.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

TP53, APC, AMER1, DOT1L ndi FAT3 ndi omwe ali pamwamba pa jini za Colorectal Neuroendocrine Carcinoma. TP53 imanenedwa mu 28.6% ya odwala oyimira m'mayesero onse azachipatala. Ndipo APC imanenedwa mu 21.4%. Deta yophatikizidwa ya odwala imakhudza zaka kuyambira mpaka . 48.1 % ya data ya odwala amadziwika kuti ndi amuna. The Colorectal Neuroendocrine Carcinoma biology pamodzi ndi ma genetics omwe adanenedwa palimodzi amatanthauzira kuchuluka kwa anthu omwe amayimiridwa ndi njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Zakudya ndi Zowonjezera za Colorectal Neuroendocrine Carcinoma

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani PEPPER Wamasamba (CAPSICUM) kapena YAM?

Tsabola Zamasamba (capsicum) zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Quercetin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga JAK-STAT Signaling, Angiogenesis ndi Cell Cycle ndi ena. Tsabola (capsicum) amalimbikitsidwa pa Colorectal Neuroendocrine Carcinoma pamene chithandizo cha khansa chopitirira ndi Lanreotide. Izi zili choncho chifukwa Tsabola (capsicum) imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Lanreotide.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu masamba a Yam ndi Apigenin, Curcumin, Lupeol, Daidzein, Catechol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. Zilazi ndizosavomerezeka ku Colorectal Neuroendocrine Carcinoma pamene chithandizo cha khansa chikupitirirabe ndi Lanreotide chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisagonjetsedwe kapena kusalabadira.

PILIPALA WA MASAMBA (CAPSICUM) AMADALITSIDWA PA YAM KWA Colorectal Neuroendocrine Carcinoma NDI Mchiritso Lanreotide.

Sankhani Chipatso BAYBERRY kapena PUMMELO?

Zipatso za Bayberry zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Daidzein, Catechol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Angiogenesis, JAK-STAT Signaling ndi Cell Cycle ndi ena. Bayberry akulimbikitsidwa ku Colorectal Neuroendocrine Carcinoma pamene chithandizo cha khansa chopitirira ndi Lanreotide. Izi ndichifukwa choti Bayberry imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse Lanreotide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Pummelo ndi Apigenin, Curcumin, Lupeol, Quercetin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. Pummelo siyovomerezeka kwa Colorectal Neuroendocrine Carcinoma pamene chithandizo cha khansa chikupitirirabe ndi Lanreotide chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamvepo kapena kuti chisamayankhe.

FRUIT BAYBERRY AMAKONZEDWA KUPANDA PUMMELO KWA Colorectal Neuroendocrine Carcinoma NDI MALANGIZO A Lanreotide.

Sankhani Nut BUTTERNUT kapena HICKORY NUT?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Daidzein, Catechol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, Angiogenesis, JAK-STAT Signaling ndi Cell Cycle ndi ena. Butternut amalangizidwa pa Colorectal Neuroendocrine Carcinoma pamene chithandizo cha khansa chopitirira ndi Lanreotide. Izi zili choncho chifukwa Butternut imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Lanreotide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Hickory Nut ndi Apigenin, Curcumin, Lupeol, Daidzein, Catechol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. Hickory Nut ndiyosavomerezeka kwa Colorectal Neuroendocrine Carcinoma pamene chithandizo cha khansa chikupitilira Lanreotide chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.

BUTTERNUT AMADALITSIDWA PAMBUYO WA HICKORY WA Colorectal Neuroendocrine Carcinoma NDI MALANGIZO A Lanreotide.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha chibadwa cha Colorectal Neuroendocrine Carcinoma kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani Masamba GIANT BUTTERBUR kapena MALABAR SPINACH?

Masamba a Giant Butterbur ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Lupeol, Daidzein, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress, Angiogenesis, Cell Cycle ndi PI3K-AKT-MTOR Signaling ndi ena. Giant Butterbur ikulimbikitsidwa kuti ikhale pachiwopsezo cha Colorectal Neuroendocrine Carcinoma pomwe chiwopsezo chokhudzana ndi majini ndi AMER1. Izi ndichifukwa choti Giant Butterbur imakulitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Malabar Sipinachi ndi Curcumin, Apigenin, Lupeol, Daidzein, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi ena. Malabar Sipinachi sivomerezedwa ngati chiwopsezo cha Colorectal Neuroendocrine Carcinoma chikugwirizana ndi chiwopsezo cha majini ndi AMER1 chifukwa chimawonjezera njira zake.

BUTTERBUR WAKUMALO WA ZABWENZI AKUKONZEDWA PA MALABAR SPINACH KWA AMER1 GENETIC RISK OF CANCER.

Sankhani Chipatso NANCE kapena SAPODILLA?

Zipatso za Nance zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Lupeol, Daidzein, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress, Angiogenesis, Cell Cycle ndi PI3K-AKT-MTOR Signaling ndi ena. Nance akulimbikitsidwa pachiwopsezo cha Colorectal Neuroendocrine Carcinoma pomwe chiwopsezo chokhudzana ndi majini ndi AMER1. Izi ndichifukwa choti Nance amawonjezera njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso za Sapodilla ndi Curcumin, Apigenin, Lupeol, Daidzein, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi ena. Sapodilla sivomerezedwa ngati chiwopsezo cha Colorectal Neuroendocrine Carcinoma chikugwirizana ndi chiwopsezo cha chibadwa ndi AMER1 chifukwa chimawonjezera njira zake.

FRUIT NANCE AKUKONZEDWA PA SAPODILLA KWA AMER1 GENETIC RISK OF CANCER.

Sankhani Nut COMMON HAZELNUT kapena EUROPEAN CHESTNUT?

Mtedza wamba wa Hazelnut uli ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Lupeol, Daidzein, Phloretin, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress, Angiogenesis, Cell Cycle ndi PI3K-AKT-MTOR Signaling ndi ena. Mtedza Wamba wa Hazelnut umalimbikitsidwa kuti ukhale pachiwopsezo cha Colorectal Neuroendocrine Carcinoma pamene chiwopsezo cha chibadwa ndi AMER1. Izi ndichifukwa choti Common Hazelnut imachulukitsa njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Curcumin, Apigenin, Lupeol, Ellagic Acid, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga WNT Beta Catenin Signaling, Oxidative Stress ndi Stem Cell Signaling ndi ena. European Chestnut sivomerezedwa ngati chiwopsezo cha Colorectal Neuroendocrine Carcinoma chikugwirizana ndi chiwopsezo cha majini ndi AMER1 chifukwa chimawonjezera ma signature awo.

HAZELNUT WAMWAMBA IMADALITSIDWA PA CHESTNUT YA KU ULAYA KWA AMER1 GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zosankhidwa ndi zosankha zofunika pa khansa monga Colorectal Neuroendocrine Carcinoma. Odwala a Colorectal Neuroendocrine Carcinoma komanso anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Colorectal Neuroendocrine Carcinoma, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Tsabola (kapsicum) chimakhala ndi zinthu zosiyanasiyana zopezeka m'mitundu yosiyanasiyana, zomwe zimakhudzanso njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa malingaliro onse poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha Colorectal Neuroendocrine Carcinoma?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Pan Origid 2020
• Mawonekedwe osinthika a khansa ya metastatic adawululidwa kuchokera kwa odwala 10,000 omwe akuyembekezeka.
• β-Caryophyllene imalepheretsa kukula kwa chotupa cholimba komanso metastasis ya lymph node ya B16F10 maselo a melanoma mu mbewa za C57BL / 6N zonenepa kwambiri.
• Eriodictyol imakhala ndi zochita zamphamvu zolimbana ndi khansa yolimbana ndi khansa ya m'mapapo ya munthu ya A549 poyambitsa mitochondrial-mediated apoptosis, G2/M cell cycle kumangidwa komanso kuletsa njira yosayina ya m-TOR/PI3K/Akt.
• Kuwongolera koyipa kwa transducer ya ma signal ndi activator ya transcript-3 signing cascade ndi lupeol imalepheretsa kukula ndikupangitsa apoptosis mu cell hepatocellular carcinoma.