Yam mob qog noj ntshav twg yuav tau txais txiaj ntsig los ntawm suav nrog Green Tea hauv lawv cov zaub mov?

highlights

Tshuaj yej ntsuab tau lees paub dav rau nws cov txiaj ntsig kev noj qab haus huv thiab nquag siv los ntawm cov neeg mob qog noj ntshav thiab cov neeg muaj kev pheej hmoo ntawm caj ces. Txawm li cas los xij, kev nyab xeeb thiab kev ua tau zoo ntawm Green Tea rau cov neeg mob qog noj ntshav yog nyob ntawm ntau yam xws li kab mob qog noj ntshav, kws khomob, lwm yam kev kho mob, thiab qog cov caj ces. Paub tias qee cov khoom noj thiab tshuaj ntxiv, xws li txiv kab ntxwv qaub thiab spinach, tuaj yeem cuam tshuam tsis zoo nrog cov tshuaj mob qog noj ntshav thiab ua rau muaj kev phiv tsis zoo yog qhov tseem ceeb.

Kev noj zaub mov yog qhov tseem ceeb rau kev kho mob qog noj ntshav vim nws tuaj yeem cuam tshuam txog kev kho mob. Cov neeg mob qog noj ntshav yuav tsum ua tib zoo xaiv thiab muab cov khoom noj uas tsim nyog thiab ntxiv rau hauv lawv cov zaub mov. Piv txwv li, Green Tea tuaj yeem muaj txiaj ntsig zoo rau cov neeg uas muaj tus kab mob hauv lub hauv paus pib ntawm Avastin, tab sis nws yuav tsis zoo rau cov neeg mob uas tau txais Radiation rau Primary Sinonasal Adenocarcinoma. Tsis tas li ntawd, thaum Green Tea tuaj yeem pab cov tib neeg uas muaj kev pheej hmoo ntawm caj ces "CDH1", nws yuav tsis raug qhia rau cov neeg uas muaj kev pheej hmoo ntawm caj ces "ERBB2". Kev kho tus kheej cov phiaj xwm noj zaub mov raws li kev noj qab haus huv, kev kho mob, thiab caj ces yog qhov tseem ceeb.

Kev nkag siab tias kev txiav txim siab txog qhov tsim nyog ntawm Green Tea rau tus neeg mob qog noj ntshav yuav tsum tau ua tus kheej yog qhov tseem ceeb. Cov yam tseem ceeb xws li hom mob qog noj ntshav, txoj kev kho mob, tshuaj pleev ib ce, kev pheej hmoo ntawm caj ces, hnub nyoog, lub cev hnyav, thiab kev ua neej yog qhov tseem ceeb hauv kev txiav txim siab yog Green Tea yog qhov kev xaiv tsim nyog. Genetics thiab genomics, tshwj xeeb, yog qhov tseem ceeb rau kev txiav txim siab. Txij li cov xwm txheej no tuaj yeem hloov pauv tau, nws yog qhov tseem ceeb uas yuav tsum tau saib xyuas thiab hloov cov kev xaiv noj zaub mov kom haum rau cov kev hloov pauv hauv kev noj qab haus huv thiab kev kho mob.

Hauv kev xaus, ib txoj hauv kev zoo rau kev xaiv noj zaub mov yog qhov tseem ceeb, tsom mus rau tag nrho cov txiaj ntsig ntawm tag nrho cov khoom siv hauv cov khoom noj / tshuaj ntxiv xws li Green Tea es tsis txhob ntsuas txhua yam khoom xyaw sib cais lossis tsis quav ntsej nws kiag li. Qhov kev xav dav no txhawb nqa ntau qhov laj thawj thiab kev tshawb fawb txog kev npaj noj zaub mov rau mob qog noj ntshav.

Saib me me hais

Kev siv cov khoom noj thiab cov khoom siv cog qoob loo, xws li cov vitamins, tshuaj ntsuab, zaub mov, probiotics, thiab ntau yam tshuaj tshwj xeeb, tau nce ntawm cov neeg mob qog noj ntshav. Cov tshuaj no yog tsim los kom xa cov ntsiab lus siab ntawm cov khoom xyaw tshwj xeeb, ntau yam kuj muaj nyob hauv cov khoom noj sib txawv. Qhov concentration thiab ntau yam ntawm cov khoom xyaw nquag sib txawv ntawm tag nrho cov khoom noj thiab cov tshuaj ntxiv. Cov zaub mov feem ntau muaj ntau yam khoom xyaw tab sis nyob rau hauv qis dua, thaum cov tshuaj ntxiv muab ntau dua ntawm cov khoom xyaw tshwj xeeb.

Xav txog qhov sib txawv ntawm kev tshawb fawb thiab kev ua haujlwm lom neeg ntawm txhua yam khoom muaj nyob rau ntawm qib molecular, nws yog ib qho tseem ceeb uas yuav tsum tau them nyiaj rau qhov sib xyaw ua ke ntawm cov khoom no thaum txiav txim siab txog cov khoom noj thiab cov tshuaj noj los tsis noj.

Cov lus nug tseem ceeb tshwm sim: Koj puas yuav tsum koom nrog Green Tea rau hauv koj cov zaub mov ua khoom noj lossis ntxiv? Puas yog nws pom zoo kom haus Green Tea yog tias koj muaj caj ces mob qog noj ntshav cuam tshuam nrog CDH1 noob? Yuav ua li cas yog tias koj qhov kev pheej hmoo caj ces yog los ntawm ERBB2 noob? Puas yog nws muaj txiaj ntsig los suav nrog Green Tea hauv koj cov zaub mov yog tias koj tau kuaj pom tus mob Primary Sinonasal Adenocarcinoma, lossis yog tias koj qhov kev kuaj mob yog Primary Solitary Fibrous Tumor? Tsis tas li ntawd, koj yuav tsum tau noj tshuaj ntsuab li cas yog tias koj tab tom kho Avastin lossis yog tias koj txoj kev npaj khomob hloov ntawm Avastin mus rau Radiation? Nws yog ib qho tseem ceeb kom paub meej tias cov lus qhia yooj yim xws li 'Green Tea yog ntuj, yog li nws ib txwm muaj txiaj ntsig' lossis 'Green Tea boosts immunity' tsis txaus rau kev paub txog zaub mov / kev xaiv ntxiv.

Tsis tas li ntawd, nws yog ib qho tseem ceeb kom rov ntsuam xyuas qhov tsim nyog ntawm kev suav nrog Green Tea hauv koj cov zaub mov yog tias muaj kev hloov pauv hauv koj txoj kev kho mob. Hauv cov ntsiab lus, thaum txiav txim siab txog kev koom nrog cov khoom noj lossis tshuaj ntxiv xws li Green Tea rau hauv koj cov khoom noj rau nws cov txiaj ntsig, koj yuav tsum xav txog tag nrho cov tshuaj biochemical ntawm txhua cov khoom xyaw, xav txog yam xws li hom mob qog noj ntshav, kev kho mob tshwj xeeb uas koj tab tom raug, caj ces. predispositions, thiab kev xaiv txoj kev ua neej.

cancer

Mob qog noj ntshav tseem yog ib qho teeb meem tseem ceeb hauv kev kho mob, feem ntau ua rau muaj kev ntxhov siab ntau. Txawm li cas los xij, kev nce qib tsis ntev los no tau txhim kho cov txiaj ntsig kev kho mob, tshwj xeeb tshaj yog los ntawm kev kho tus kheej txoj hauv kev, kev tshuaj xyuas tsis raug siv cov ntshav thiab qaub ncaug, thiab kev txhim kho ntawm kev tiv thaiv kab mob. Kev tshawb pom ntxov thiab kev cuam tshuam raws sijhawm yog qhov tseem ceeb hauv kev cuam tshuam zoo rau tag nrho cov txiaj ntsig kev kho mob.

Kev ntsuam xyuas caj ces muab cov lus cog tseg tseem ceeb hauv kev ntsuam xyuas kev pheej hmoo mob qog noj ntshav thiab kev raug mob ntxov ntxov. Txawm li cas los xij, rau ntau tus neeg uas muaj tsev neeg thiab noob caj noob ces predispositions rau mob qog noj ntshav, kev xaiv rau kev kho mob, txawm tias nrog kev saib xyuas tsis tu ncua, feem ntau txwv lossis tsis muaj. Thaum kuaj pom tias muaj qee yam mob qog noj ntshav, xws li Primary Solitary Fibrous Tumor lossis Primary Sinonasal Adenocarcinoma, cov tswv yim kho mob yuav tsum tau kho raws li tus neeg mob qog caj ces, theem ntawm tus kab mob, nrog rau yam xws li hnub nyoog thiab poj niam txiv neej. "

Tom qab kev kho mob, kev saib xyuas tsis tu ncua yog qhov tseem ceeb txhawm rau txheeb xyuas cov cim qhia ntawm kev mob qog noj ntshav thiab qhia txog kev txiav txim siab tom ntej. Ntau tus neeg mob qog noj ntshav thiab cov neeg muaj kev pheej hmoo feem ntau nrhiav kev qhia txog kev sib koom ua ke qee yam khoom noj thiab tshuaj ntxiv rau hauv lawv cov zaub mov, uas ua lub luag haujlwm tseem ceeb hauv lawv txoj kev txiav txim siab tag nrho txog kev tswj hwm kev noj qab haus huv.

Cov lus nug tseem ceeb yog seb puas yuav ua rau muaj kev pheej hmoo ntawm caj ces thiab kev kuaj mob qog noj ntshav tshwj xeeb thaum txiav txim siab txog kev noj zaub mov, xws li Green Tea. Puas muaj kev pheej hmoo ntawm caj ces rau mob qog noj ntshav los ntawm kev hloov pauv hauv CDH1 muaj tib txoj hauv kev biochemical cuam tshuam raws li kev hloov pauv hauv ERBB2? Los ntawm kev noj zaub mov zoo, qhov kev pheej hmoo puas cuam tshuam nrog Primary Solitary Fibrous Tumor sib npaug rau Primary Sinonasal Adenocarcinoma? Tsis tas li ntawd, puas yog kev xav txog kev noj zaub mov zoo ib yam rau cov uas tau txais Radiation rau cov neeg tau txais Avastin? Cov kev txiav txim siab no yog qhov tseem ceeb hauv kev txiav txim siab xaiv zaub mov rau cov tib neeg uas muaj kev pheej hmoo ntawm caj ces thiab kev kho mob qog noj ntshav.

Ntsuab tshuaj yej - Ib qho khoom noj khoom haus ntxiv

Cov tshuaj ntsuab ntxiv suav nrog ntau yam khoom xyaw, suav nrog Geraniin, Epigallocatechin Gallate, Epicatechin Gallate, Rutin thiab Epigallocatechin 3-(3-methylgallate), txhua qhov tam sim no ntawm ntau qhov sib txawv. Cov khoom xyaw no cuam tshuam rau txoj hauv kev molecular, tshwj xeeb yog MYC Signaling, Notch Signaling, PI3K-AKT-MTOR Signaling thiab Oncogenic Histone Methylation, uas tswj hwm qhov tseem ceeb ntawm kev mob qog noj ntshav ntawm qib cellular, xws li qog loj hlob, kis, thiab kev tuag ntawm tes. Muab cov tshuaj lom neeg no, xaiv cov tshuaj uas tsim nyog xws li Green Tea, ib leeg lossis ua ke, dhau los ua qhov kev txiav txim siab tseem ceeb hauv cov ntsiab lus ntawm kev noj zaub mov zoo. Thaum xav txog kev siv Green Tea rau mob qog noj ntshav, nws yog ib qho tseem ceeb uas yuav tau xav txog ntau yam thiab cov txheej txheem no. Qhov no yog vim hais tias, zoo ib yam li kev kho mob qog noj ntshav, kev siv Green Tea tsis yog qhov kev txiav txim siab thoob ntiaj teb tsim nyog rau txhua tus mob qog noj ntshav tab sis yuav tsum tau ua tus kheej.

Xaiv cov tshuaj yej ntsuab ntxiv

Hais txog lo lus nug 'Thaum twg kuv yuav tsum zam Green Tea hauv cov ntsiab lus ntawm Cancer' yog qhov nyuaj vim tias cov lus teb yog tus kheej heev - nws tsuas yog 'Zoo!'. Zoo ib yam li kev kho mob qog noj ntshav yuav tsis zoo rau txhua tus neeg mob, qhov cuam tshuam thiab kev nyab xeeb lossis cov txiaj ntsig ntawm Green Tea txawv nyob ntawm tus kheej. Tej yam xws li hom mob kheesxaws, genetic predispositions, kev kho mob tam sim no, lwm yam tshuaj tau noj, kev ua neej nyob, BMI, thiab kev ua xua txhua yam ua lub luag haujlwm hauv kev txiav txim siab seb Green Tea puas tsim nyog lossis yuav tsum zam, qhia txog qhov tseem ceeb ntawm tus kheej xav txog. nyob rau hauv tej kev txiav txim.

1. Cov Tshuaj Ntsuab Tshuaj Ntsuab puas puas muaj txiaj ntsig rau Thawj Tus Neeg Mob Sinonasal Adenocarcinoma uas tau txais kev kho hluav taws xob?

Thawj Sinonasal Adenocarcinoma yog tus cwj pwm los ntawm kev hloov pauv caj ces, xws li ATRX, NOTCH1 thiab PTPRD, uas ua rau muaj kev hloov pauv hauv biochemical pathways, tshwj xeeb tshaj yog Notch Signaling thiab RUNX Signaling. Kev ua tau zoo ntawm kev kho mob qog noj ntshav, xws li Radiation, yog qhov cuam tshuam rau nws cov txheej txheem ntawm kev ua haujlwm ntawm cov kev tshwj xeeb no. Lub tswv yim zoo tshaj plaws suav nrog kev kho cov kev kho mob nrog rau txoj hauv kev uas ua rau mob qog noj ntshav, yog li ua kom muaj tus kheej thiab muaj txiaj ntsig zoo. Hauv cov xwm txheej zoo li no, tsis txhob noj zaub mov lossis khoom noj khoom haus uas tuaj yeem tiv thaiv kev kho mob lossis txo qis qhov kev sib tw no yog qhov tseem ceeb. Piv txwv li, Green Tea ntxiv, uas cuam tshuam rau Notch Signaling, yuav tsis yog qhov kev xaiv zoo nyob rau hauv rooj plaub ntawm Primary Sinonasal Adenocarcinoma thaum raug hluav taws xob. Qhov no yog vim nws yuav ua rau tus kab mob hnyav zuj zus los yog cuam tshuam nrog kev kho mob. Thaum xaiv ib txoj kev npaj khoom noj khoom haus, nws tseem ceeb heev uas yuav tau xav txog yam xws li hom mob qog noj ntshav, kev kho mob tsis tu ncua, hnub nyoog, poj niam txiv neej, BMI, txoj kev ua neej, thiab txhua yam kev hloov pauv caj ces.

2. Cov Tshuaj Ntsuab Tshuaj Ntsuab puas yuav pab tau rau cov neeg mob uas tau txais kev kho mob Avastin thawj zaug?

Cov qog nqaij hlav hauv plab yog txheeb xyuas los ntawm cov kev hloov caj ces tshwj xeeb, xws li BRD4, FLI1 thiab KMT2C, uas ua rau muaj kev hloov pauv hauv biochemical pathways, tshwj xeeb tshaj yog MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation thiab Amino Acid Metabolism. Kev ua tau zoo ntawm kev kho mob qog noj ntshav, zoo li Avastin, yog txiav txim siab los ntawm nws cov kev cuam tshuam nrog cov kev no. Lub hom phiaj yog los xyuas kom meej tias txoj kev kho mob ua tau zoo nrog rau txoj hauv kev uas ua rau mob qog noj ntshav, ua kom muaj kev kho tus kheej. Nyob rau hauv cov ntsiab lus no, cov khoom noj los yog cov tshuaj ntxiv uas haum rau kev kho mob lossis txhim kho qhov kev sib raug zoo no yuav tsum raug txiav txim siab. Piv txwv li, Green Tea ntxiv yog ib qho kev xaiv muaj txiaj ntsig rau cov neeg uas muaj cov qog nqaij hlav hauv plab uas muaj Avastin. Qhov no yog vim tias Ntsuab Tshuaj yej cuam tshuam rau txoj hauv kev xws li MYC Signaling, uas tuaj yeem cuam tshuam cov yam tseem ceeb uas ua rau lub hauv paus tseem ceeb ntawm cov qog nqaij hlav lossis cov txiaj ntsig zoo ntawm Avastin.

3. Cov tshuaj yej ntsuab puas muaj kev nyab xeeb rau cov tib neeg noj qab haus huv nrog ERBB2 Mutation Associated Genetic Risk?

Ntau lub tuam txhab muab cov gene panels rau kev ntsuam xyuas cov kev pheej hmoo ntawm cov qog nqaij hlav sib txawv. Cov vaj huam sib luag no suav nrog cov noob txuas rau lub mis, zes qe menyuam, uterine, prostate, thiab qog nqaij hlav plab. Kev ntsuam xyuas cov noob no tuaj yeem lees paub qhov kev kuaj mob thiab qhia txog kev kho thiab tswj cov tswv yim. Kev txheeb xyuas qhov sib txawv uas ua rau muaj kab mob tuaj yeem pab ntxiv rau hauv kev sim thiab kuaj xyuas cov txheeb ze uas yuav muaj kev pheej hmoo. Cov noob ERBB2 feem ntau suav nrog hauv cov vaj huam sib luag no rau kev ntsuas kev pheej hmoo mob qog noj ntshav.

Kev hloov pauv hauv ERBB2 noob cuam tshuam rau txoj hauv kev biochemical lossis cov txheej txheem, xws li Growth Factor Signaling thiab PI3K-AKT-MTOR Signaling, uas cuam tshuam ncaj qha lossis cuam tshuam rau kev tsav mob qog noj ntshav ntawm qib molecular. Thaum lub vaj huam sib luag caj ces txheeb xyuas qhov kev hloov pauv hauv ERBB2 cuam tshuam nrog kev pheej hmoo siab ntawm Esophageal Adenocarcinoma, qhov laj thawj kev tshawb fawb qhia tias tsis txhob siv tshuaj ntsuab ntxiv. Qhov no yog vim hais tias ntxiv Green Tea cuam tshuam txoj hauv kev zoo li PI3K-AKT-MTOR Cov Teeb Meem, uas tuaj yeem ua rau muaj kev cuam tshuam tsis zoo hauv cov ntsiab lus ntawm ERBB2 kev hloov pauv thiab lwm yam mob qog noj ntshav.

4. Cov tshuaj yej ntsuab puas muaj kev nyab xeeb rau cov tib neeg noj qab haus huv nrog CDH1 Mutation Associated Genetic Risk?

CDH1 ua lub luag haujlwm tseem ceeb hauv kev ntsuas kev pheej hmoo mob qog noj ntshav. Kev hloov pauv hauv CDH1 tuaj yeem cuam tshuam txoj hauv kev biochemical tseem ceeb, suav nrog Oncogenic Histone Methylation, Adherens junction thiab Epithelial mus rau Mesenchymal Hloov, uas cuam tshuam rau kev txhim kho qog noj ntshav. Yog tias koj lub vaj huam sib luag caj ces qhia txog kev hloov pauv hauv CDH1 cuam tshuam nrog Gastric Cancer, xav txog kev siv tshuaj ntsuab tshuaj ntsuab hauv koj txoj kev npaj zaub mov. Cov tshuaj no tuaj yeem cuam tshuam txoj hauv kev zoo li Oncogenic Histone Methylation, tau txais txiaj ntsig los ntawm kev muab kev txhawb nqa cuam tshuam rau cov tib neeg uas muaj CDH1 hloov pauv thiab cuam tshuam txog kev noj qab haus huv.

Nyob rau hauv Xaus

Ob yam tseem ceeb tshaj plaws uas yuav tsum nco ntsoov yog tias kev kho mob qog noj ntshav thiab noj zaub mov tsis zoo ib yam rau txhua tus. Khoom noj khoom haus, suav nrog zaub mov thiab tshuaj ntxiv xws li Green Tea, yog cov cuab yeej siv tau zoo uas tuaj yeem tswj tau los ntawm koj thaum ntsib mob qog noj ntshav.

"Kuv yuav tsum noj dab tsi?" yog cov lus nug uas feem ntau nug los ntawm cov neeg mob qog noj ntshav thiab cov uas muaj feem yuav mob qog noj ntshav. Cov lus teb raug yog tias nws nyob ntawm yam xws li hom mob qog noj ntshav, noob caj noob ces ntawm qog, kev kho tam sim no, kev ua xua, kev ua neej nyob, thiab BMI.

Tau txais koj cov khoom noj khoom haus tus kheej rau kev mob qog noj ntshav los ntawm addon los ntawm nias qhov txuas hauv qab no thiab teb cov lus nug txog koj hom mob qog noj ntshav, kev kho mob, kev ua neej, kev ua xua, hnub nyoog, thiab poj niam txiv neej.

References

• cBioPortal rau Cancer Genomics
• Kev tshem tawm ntawm lipopolysaccharide-induced nuclear factor-kappaB kev ua los ntawm theaflavin-3,3'-digallate los ntawm cov tshuaj yej dub thiab lwm yam polyphenols los ntawm down-regulation ntawm IkappaB kinase kev ua hauv macrophages.
• cBioPortal rau Cancer Genomics
• Kev hloov pauv toj roob hauv pes ntawm mob qog noj ntshav metastatic tau qhia los ntawm kev soj ntsuam tom ntej ntawm 10,000 tus neeg mob.