Khoom noj rau Chondrosarcoma!

Introduction

Cov khoom noj rau Chondrosarcoma yuav tsum yog tus kheej rau txhua tus neeg thiab yuav tsum hloov kho thaum kho mob qog noj ntshav lossis qog caj ces hloov pauv. Kev kho tus kheej thiab kev hloov pauv yuav tsum xav txog tag nrho cov khoom xyaw nquag lossis bioactives muaj nyob rau hauv cov khoom noj sib txawv nrog rau kev mob qog noj ntshav, noob caj noob ces, kev kho mob, kev ua neej nyob thiab kev nyiam noj zaub mov. Li no thaum kev noj haus yog ib qho kev txiav txim siab tseem ceeb heev rau tus neeg mob qog noj ntshav thiab tus neeg muaj kev pheej hmoo ntawm mob qog noj ntshav - yuav ua li cas xaiv cov zaub mov noj tsis yog ib txoj haujlwm yooj yim.

Chondrosarcoma yog ib qho mob qog nqaij hlav uas tsim los ntawm cov pob txha mos. Pob txha mos yog cov ntaub so ntswg mos uas tso cai rau txav ntawm pob txha thiab pob qij txha. Chondrosarcoma tuaj yeem cuam tshuam rau txiv neej thiab poj niam sib npaug thiab txhim kho rau cov tib neeg hnub nyoog ntawm 40 thiab 75 xyoo. Muaj ntau ntau hom chondrosarcomas xws li ntshiab cell chondrosarcoma, dedifferentiated chondrosarcoma thiab mesenchymal chondrosarcoma. Cov tsos mob ntawm chondrosarcoma tuaj yeem sib txawv nyob ntawm qhov chaw thiab qhov loj ntawm cov qog, nrog rau qaug zog, ua npaws thiab tsis txhob poob phaus. Cov tsos mob ntawm chondrosarcoma nyob ntawm ntau yam, nrog rau qib thiab theem ntawm cov qog. Kev kho mob rau chondrosarcoma tuaj yeem suav nrog kev phais, kev kho hluav taws xob, thiab tshuaj khomob, kho rau tus neeg mob.

Rau Chondrosarcoma nws puas muaj teeb meem dab tsi zaub, txiv hmab txiv ntoo, txiv ntoo, noob noj?

Cov lus nug txog kev noj zaub mov ntau ntau nug los ntawm cov neeg mob qog noj ntshav thiab cov tib neeg uas muaj kev pheej hmoo ntawm qog noj ntshav yog - rau cov qog nqaij hlav xws li Chondrosarcoma nws puas muaj teeb meem yam khoom noj uas kuv noj thiab kuv tsis ua? Los yog yog tias kuv ua raws li kev noj zaub mov zoo yog qhov txaus rau mob qog noj ntshav zoo li Chondrosarcoma?

Piv txwv li nws puas tseem ceeb yog tias zaub Cabbage noj ntau dua piv rau Towel Gourd? Nws puas muaj qhov txawv yog tias cov txiv hmab txiv ntoo Longan nyiam dua European Cranberry? Tsis tas li yog tias cov kev xaiv zoo sib xws tau tsim rau cov txiv ntoo / cov noob zoo li Butternut dhau European Chestnut thiab rau cov pulses zoo li Gram Bean tshaj Pigeon Pea. Thiab yog tias kuv noj dab tsi tseem ceeb - ces yuav ua li cas thiaj paub cov khoom noj uas pom zoo rau Chondrosarcoma thiab nws puas yog tib lo lus teb rau txhua tus neeg uas muaj tib yam kev kuaj mob lossis kev pheej hmoo ntawm caj ces?

Yog lawm! Cov zaub mov koj noj tseem ceeb rau Chondrosarcoma!

Cov lus pom zoo yuav tsis zoo ib yam rau txhua tus thiab tuaj yeem sib txawv txawm tias tib yam kev kuaj mob thiab kev pheej hmoo ntawm caj ces.

Txhua yam khoom noj ( zaub, txiv hmab txiv ntoo, txiv ntseej, noob, pulses, roj thiab lwm yam) thiab cov khoom noj khoom haus yog tsim los ntawm ntau tshaj ib qho khoom xyaw molecular lossis bio-actives nyob rau hauv sib txawv proportions thiab ntau npaum. Txhua yam khoom muaj txiaj ntsig muaj qhov tshwj xeeb ntawm kev ua haujlwm - uas tuaj yeem ua kom ua haujlwm lossis inhibition ntawm ntau txoj hauv kev biochemical. Cov zaub mov uas yooj yim hais thiab cov tshuaj uas tau pom zoo yog cov uas tsis ua rau muaj kev nce ntxiv ntawm molecular tsav mob qog noj ntshav tab sis txo lawv. Lwm cov zaub mov no yuav tsum tsis pom zoo. Cov khoom noj muaj ntau yam khoom xyaw - yog li thaum ntsuas cov khoom noj thiab tshuaj ntxiv koj yuav tsum xav txog qhov cuam tshuam ntawm tag nrho cov khoom xyaw nquag ua ke ntau dua li ntawm tus kheej.

Piv txwv li, Longan muaj cov khoom xyaw nquag Curcumin, Apigenin, Lycopene, Phloretin, Daidzein. Thiab European Cranberry muaj cov khoom xyaw nquag Curcumin, Apigenin, Ellagic Acid, Quercetin, Lycopene thiab tej zaum lwm tus.

Ib qho yuam kev uas tau ua thaum txiav txim siab thiab xaiv cov zaub mov noj rau Chondrosarcoma - yog ntsuas tsuas yog xaiv cov khoom xyaw uas muaj nyob hauv cov zaub mov thiab tsis quav ntsej lwm tus. Vim tias cov khoom xyaw sib txawv uas muaj nyob hauv cov zaub mov yuav muaj kev cuam tshuam rau cov neeg mob qog noj ntshav - koj tuaj yeem tsis tuaj yeem xaiv cov khoom xyaw nquag hauv cov zaub mov thiab tshuaj ntxiv rau kev txiav txim siab noj zaub mov rau Chondrosarcoma.

YOG – KEV PAB CUAM TSHUAJ RAU QHOV TSEEB. Kev txiav txim siab txog kev noj zaub mov yuav tsum xav txog txhua yam khoom muaj txiaj ntsig ntawm cov khoom noj.

Kev txawj xav tau kev noj haus Personalization rau Chondrosarcoma?

Khoom noj khoom haus tus kheej rau cov qog nqaij hlav xws li Chondrosarcoma muaj cov khoom noj pom zoo / cov tshuaj ntxiv; tsis pom zoo cov zaub mov / tshuaj ntxiv nrog piv txwv cov zaub mov txawv uas ua ntej siv cov khoom noj pom zoo. Ib qho piv txwv ntawm kev noj zaub mov tus kheej tuaj yeem pom ntawm qhov no txuas.

Kev txiav txim siab seb cov zaub mov twg raug pom zoo los yog tsis yog qhov nyuaj heev, yuav tsum muaj kev txawj ntse hauv Chondrosarcoma biology, kev tshawb fawb txog zaub mov, noob caj noob ces, biochemistry nrog rau kev nkag siab zoo txog kev kho mob qog noj ntshav thiab cuam tshuam qhov tsis zoo uas cov kev kho mob tuaj yeem ua tsis tau.

QHOV TSEEB TSEEM CEEB TSHAJ PLAWS YUAV TSUM TAU TXAIS KEV PHEM NTAWM KEV KAWM NTAWV THOV KEV PAB CUAM yog: Kev Kho Mob BIOLOGY, FOOD SCIENCE, Kev Kho Mob Cancer thiab GENETICS.

Cov yam ntxwv ntawm cov qog nqaij hlav zoo li Chondrosarcoma

Tag nrho cov qog nqaij hlav xws li Chondrosarcoma tuaj yeem ua tus cwj pwm los ntawm cov txheej txheem biochemical - txoj kev kos npe ntawm Chondrosarcoma. Txoj kev biochemical zoo li Hypoxia, MAPK Signaling, Oncogenic Cancer Epigenetics, Zog Metabolism yog ib feem ntawm kos npe txhais ntawm Chondrosarcoma. Txhua tus neeg tus kab mob qog noj ntshav tuaj yeem sib txawv thiab yog li lawv qhov tshwj xeeb kos npe mob qog noj ntshav yuav txawv.

Cov kev kho mob uas muaj txiaj ntsig zoo rau Chondrosarcoma yuav tsum tau paub txog cov txheej txheem kev kos npe biochemical rau txhua tus neeg mob qog noj ntshav thiab ib tus neeg muaj kev pheej hmoo ntawm caj ces. Yog li kev kho mob sib txawv nrog cov txheej txheem sib txawv ntawm kev ua haujlwm zoo rau cov neeg mob sib txawv. Ib yam li ntawd thiab rau tib lub laj thawj khoom noj thiab tshuaj ntxiv yuav tsum tau ua tus kheej rau txhua tus neeg. Li no, qee cov zaub mov thiab tshuaj ntxiv tau pom zoo rau Chondrosarcoma thaum noj Pazopanib kho mob qog noj ntshav, thiab qee cov zaub mov thiab tshuaj tsis pom zoo.

Qhov chaw zoo li cBioPortal thiab ntau lwm tus muab cov neeg sawv cev ntawm tus neeg mob tsis qhia npe cov ntaub ntawv los ntawm kev sim tshuaj rau txhua qhov qhia txog mob qog noj ntshav. Cov ntaub ntawv no muaj cov ntaub ntawv tshawb fawb soj ntsuam xws li tus qauv loj / tus naj npawb ntawm cov neeg mob, pawg hnub nyoog, poj niam txiv neej, haiv neeg, kev kho mob, qog qhov chaw thiab txhua yam kev hloov caj ces.

TP53, IDH1, TET2, EPHA7 thiab ATRX yog cov npe saum toj kawg nkaus tshaj tawm cov noob rau Chondrosarcoma. TP53 tau tshaj tawm hauv 13.5% ntawm cov neeg sawv cev ntawm cov neeg mob thoob plaws txhua qhov kev sim tshuaj. Thiab IDH1 tau tshaj tawm hauv 13.5%. Cov ntaub ntawv qhia cov neeg mob ua ke suav nrog hnub nyoog ntawm 14 txog 79. 66.4% ntawm cov ntaub ntawv tus neeg mob raug txheeb xyuas tias yog txiv neej. Lub Chondrosarcoma biology nrog rau kev tshaj tawm cov noob caj noob ces ua ke txhais cov pej xeem sawv cev rau kev kos npe biochemical rau tus kabmob no. Yog hais tias tus neeg mob qog nqaij hlav qog nqaij hlav caj ces lossis cov caj ces ua rau muaj kev pheej hmoo kuj paub, qhov ntawd yuav tsum tau siv rau kev noj zaub mov tus kheej.

Kev xaiv noj zaub mov yuav tsum sib phim nrog txhua tus tib neeg tus CANCER kos npe.

Khoom noj khoom haus thiab tshuaj ntxiv rau Chondrosarcoma

Rau Cov Neeg Mob Cancer

Cov neeg mob qog noj ntshav ntawm kev kho mob lossis kev kho mob palliative yuav tsum tau txiav txim siab txog zaub mov thiab tshuaj ntxiv - rau cov calories uas xav tau kev noj haus, rau kev tswj hwm cov kev mob tshwm sim thiab kev kho mob qog noj ntshav. Tag nrho cov khoom noj uas muaj cov nroj tsuag tsis sib npaug thiab xaiv thiab saib xyuas cov khoom noj uas yog tus kheej thiab kho rau kev kho mob qog noj ntshav tsis tu ncua yog qhov tseem ceeb thiab nyuaj. Nov yog qee qhov piv txwv muab cov lus qhia rau kev txiav txim siab noj zaub mov.

Xaiv Zaub CABBAGE los yog TOWEL GOURD?

Zaub Cabbage muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Apigenin, Quercetin, Benzyl Isothiocyanate, Lycopene. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li PI3K-AKT-MTOR Kev Tshaj Tawm, Epithelial rau Mesenchymal Hloov thiab MYC Signaling thiab lwm yam. Cabbage raug pom zoo rau Chondrosarcoma thaum kho mob qog noj ntshav tsis tu ncua yog Pazopanib. Qhov no yog vim tias Cabbage hloov cov txheej txheem biochemical uas tau tshaj tawm tshawb fawb los ua kom cov nyhuv ntawm Pazopanib.

Qee cov khoom xyaw nquag lossis bioactives hauv zaub phuam Gourd yog Curcumin, Apigenin, Lycopene, Phloretin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling, Notch Signaling thiab MAPK Signaling thiab lwm yam. Cov phuam da dej tsis pom zoo rau Chondrosarcoma thaum kho mob qog noj ntshav tsis tu ncua yog Pazopanib vim nws hloov kho cov txheej txheem biochemical uas ua rau kev kho mob qog noj ntshav tsis zoo lossis tsis teb.

Cabbage zaub tau pom zoo tshaj cov phuam da dej rau Chondrosarcoma thiab kho Pazopanib.

Xaiv Txiv Hmab Txiv Ntoo EUROPEAN CRANBERRY lossis LONGAN?

Txiv Hmab Txiv Ntoo European Cranberry muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Apigenin, Ellagic Acid, Quercetin, Lycopene. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling, Epithelial rau Mesenchymal Hloov thiab Hypoxia thiab lwm yam. European Cranberry tau pom zoo rau Chondrosarcoma thaum kho mob qog noj ntshav tsis tu ncua yog Pazopanib. Qhov no yog vim tias European Cranberry hloov kho cov txheej txheem biochemical uas tau tshaj tawm tshawb fawb los ua kom muaj txiaj ntsig ntawm Pazopanib.

Qee cov khoom xyaw nquag lossis bioactives hauv txiv hmab txiv ntoo Longan yog Curcumin, Apigenin, Lycopene, Phloretin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li WNT Beta Catenin Signaling thiab Epithelial rau Mesenchymal Hloov thiab lwm yam. Longan tsis pom zoo rau Chondrosarcoma thaum kho mob qog noj ntshav tsis tu ncua yog Pazopanib vim tias nws hloov kho cov txheej txheem biochemical uas ua rau kev kho mob qog noj ntshav tsis zoo lossis tsis teb.

Txiv hmab txiv ntoo EUROPEAN CRANBERRY tau pom zoo dhau LONGAN rau Chondrosarcoma thiab kho Pazopanib.

Xaiv txiv ntseej BUTTERNUT lossis EUROPEAN CHESTNUT?

Butternut muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Apigenin, Lycopene, Phloretin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li PI3K-AKT-MTOR Kev Tshaj Tawm, Epithelial mus rau Mesenchymal Hloov, MAPK Signaling thiab Hypoxia thiab lwm yam. Butternut raug pom zoo rau Chondrosarcoma thaum kho mob qog noj ntshav tsis tu ncua yog Pazopanib. Qhov no yog vim Butternut hloov cov txheej txheem biochemical uas tau raug tshawb fawb qhia los ua kom cov nyhuv ntawm Pazopanib.

Qee yam khoom xyaw lossis bioactives hauv European Chestnut yog Curcumin, Apigenin, Ellagic Acid, Quercetin, Phloretin. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li WNT Beta Catenin Signaling thiab Epithelial rau Mesenchymal Hloov thiab lwm yam. European Chestnut tsis pom zoo rau Chondrosarcoma thaum kho mob qog noj ntshav tsis tu ncua yog Pazopanib vim nws hloov kho cov txheej txheem biochemical uas ua rau kev kho mob qog noj ntshav tsis zoo lossis tsis teb.

BUTTERNUT tau pom zoo hla Tebchaws Europe CHESTNUT rau Chondrosarcoma thiab Kev Kho Mob Pazopanib.

Rau cov tib neeg uas muaj kev pheej hmoo ntawm mob qog noj ntshav

Cov lus nug nug los ntawm cov tib neeg uas muaj kev pheej hmoo ntawm caj ces ntawm Chondrosarcoma lossis keeb kwm ntawm tsev neeg yog "Kuv Yuav Tsum Noj Dab Tsi Ua Ntej?" thiab yuav ua li cas lawv yuav tsum xaiv cov khoom noj thiab cov tshuaj ntxiv los tswj kev pheej hmoo ntawm tus kab mob. Txij li thaum muaj kev pheej hmoo mob qog noj ntshav tsis muaj ib yam dab tsi ua tau raws li kev kho mob - kev txiav txim siab ntawm cov khoom noj thiab tshuaj ntxiv ua ib qho tseem ceeb thiab ib qho ntawm ob peb yam uas yuav ua tau. Tag nrho cov khoom noj uas cog tsis sib npaug thiab raws li cov noob caj noob ces thiab kev kos npe - cov kev xaiv ntawm cov khoom noj thiab cov tshuaj yuav tsum yog tus kheej.

Xaiv Zaub CALABASH lossis DAIKON RADISH?

Zaub Calabash muaj ntau yam khoom xyaw lossis bioactives xws li Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li EPHRIN Signaling, Cell Cycle, JAK-STAT Signaling thiab P53 Signaling thiab lwm yam. Calabash tau pom zoo rau kev pheej hmoo ntawm Chondrosarcoma thaum muaj kev pheej hmoo ntawm caj ces yog ATRX. Qhov no yog vim Calabash tsub kom cov biochemical txoj kev uas counteract tus kos npe tsav tsheb ntawm nws.

Qee cov khoom xyaw nquag lossis bioactives hauv zaub Daikon Radish yog Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical zoo li Oxidative Stress thiab lwm yam. Daikon Radish tsis pom zoo thaum muaj kev pheej hmoo ntawm Chondrosarcoma thaum muaj kev pheej hmoo ntawm caj ces yog ATRX vim tias nws nce txoj hauv kev kos npe ntawm nws.

Zaub CALABASH tau pom zoo tshaj DAIKON RADISH rau ATRX genetic Risk ntawm CANCER.

Xaiv Txiv Hmab Txiv Ntoo los yog EUROPEAN PLUM?

Txiv Hmab Txiv Ntoo Txiv Hmab Txiv Ntoo muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Lupeol, Formononetin, Daidzein, Beta-sitosterol. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li Cell Cycle, JAK-STAT Signaling thiab Hypoxia thiab lwm yam. Watermelon raug pom zoo rau kev pheej hmoo ntawm Chondrosarcoma thaum muaj kev pheej hmoo ntawm caj ces yog ATRX. Qhov no yog vim Watermelon tsub kom cov biochemical txoj kev uas counteract lub kos npe tsav tsheb ntawm nws.

Qee cov khoom xyaw nquag lossis bioactives hauv cov txiv hmab txiv ntoo European Plum yog Curcumin, Lupeol, Formononetin, Daidzein, Beta-sitosterol. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li Oxidative Stress, PI3K-AKT-MTOR Signaling thiab MAPK Signaling thiab lwm yam. European Plum tsis pom zoo thaum muaj kev pheej hmoo ntawm Chondrosarcoma thaum muaj kev pheej hmoo ntawm caj ces yog ATRX vim tias nws nce txoj hauv kev kos npe ntawm nws.

Txiv Hmab Txiv Ntoo Txiv Hmab Txiv Ntoo yog pom zoo tshaj EUROPEAN PLUM FOR ATRX genetic Risk of Cancer.

Xaiv txiv ntseej COMMON HAZELNUT lossis BRAZIL NUT?

Common Hazelnut muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Quercetin, Lupeol, Formononetin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li EPHRIN Signaling, Cell Cycle, JAK-STAT Signaling thiab P53 Signaling thiab lwm yam. Common Hazelnut raug pom zoo rau kev pheej hmoo ntawm Chondrosarcoma thaum muaj kev pheej hmoo ntawm caj ces yog ATRX. Qhov no yog vim Common Hazelnut tsub kom cov biochemical pathways uas counteract lub kos npe tsav tsheb ntawm nws.

Qee yam khoom xyaw lossis bioactives hauv Brazil txiv ntoo yog Curcumin, Ellagic Acid, Lupeol, Formononetin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li Oxidative Stress, JAK-STAT Signaling thiab PI3K-AKT-MTOR Signaling thiab lwm yam. Brazil txiv ntoo tsis pom zoo thaum muaj kev pheej hmoo ntawm Chondrosarcoma thaum muaj kev pheej hmoo ntawm caj ces yog ATRX vim tias nws nce txoj hauv kev kos npe ntawm nws.

COMMON HAZELNUT tau pom zoo tshaj BRAZIL NUT rau ATRX genetic Risk ntawm CANCER.

Nyob rau hauv Xaus

Cov khoom noj thiab cov khoom noj uas tau xaiv yog cov kev txiav txim siab tseem ceeb rau cov qog nqaij hlav xws li Chondrosarcoma. Cov neeg mob Chondrosarcoma thiab cov tib neeg uas muaj kev pheej hmoo ntawm caj ces ib txwm muaj lo lus nug no: "Cov khoom noj dab tsi thiab cov khoom noj khoom haus tau pom zoo rau kuv thiab qhov twg tsis yog?" Muaj ib qho kev ntseeg uas yog ib qho kev xav tsis zoo uas txhua yam khoom noj uas cog qoob loo tuaj yeem muaj txiaj ntsig lossis tsis zoo tab sis yuav tsis muaj teeb meem. Qee cov zaub mov thiab tshuaj ntxiv tuaj yeem cuam tshuam nrog kev kho mob qog noj ntshav lossis txhawb nqa txoj hauv kev ntawm cov neeg mob qog noj ntshav.

Muaj ntau hom mob qog noj ntshav zoo li Chondrosarcoma, txhua tus muaj cov qog nqaij hlav sib txawv nrog cov kev hloov genomic ntxiv rau txhua tus neeg. Ntxiv mus, txhua txoj kev kho mob qog noj ntshav thiab kws khomob muaj qhov tshwj xeeb ntawm kev ua haujlwm. Txhua yam zaub mov zoo li Cabbage muaj ntau yam bioactives nyob rau hauv ntau qhov sib txawv, uas muaj kev cuam tshuam rau kev sib txawv thiab txawv ntawm txoj hauv kev biochemical. Lub ntsiab lus ntawm kev noj zaub mov tus kheej yog cov lus pom zoo ntawm tus kheej rau kev mob qog noj ntshav, kev kho mob, caj ces, kev ua neej thiab lwm yam. Kev txiav txim siab noj zaub mov tus kheej rau mob qog noj ntshav xav tau kev paub txog kev mob qog noj ntshav, kev tshawb fawb txog zaub mov thiab kev nkag siab txog kev kho mob sib txawv. Thaum kawg thaum muaj cov kev kho mob hloov pauv lossis cov genomics tshiab raug txheeb xyuas - cov khoom noj khoom haus tus kheej xav tau rov ntsuas dua.

Cov tshuaj addon noj tus kheej ua rau kev txiav txim siab yooj yim thiab tshem tawm tag nrho cov kev kwv yees hauv kev teb cov lus nug, "Yuav ua li cas cov zaub mov kuv xaiv los yog tsis xaiv rau Chondrosarcoma?". Pab pawg addon ntau txoj kev qhuab qhia suav nrog cov kws kho mob qog noj ntshav, kws tshawb fawb soj ntsuam, software engineers thiab cov kws tshawb fawb cov ntaub ntawv.

References

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