Khoom noj rau Ovarian Cancer!

Introduction

Cov zaub mov rau Ovarian Cancer yuav tsum yog tus kheej rau txhua tus neeg thiab yuav tsum hloov kho thaum kho mob qog noj ntshav lossis qog caj ces hloov pauv. Kev kho tus kheej thiab kev hloov pauv yuav tsum xav txog tag nrho cov khoom xyaw nquag lossis bioactives muaj nyob rau hauv cov khoom noj sib txawv nrog rau kev mob qog noj ntshav, noob caj noob ces, kev kho mob, kev ua neej nyob thiab kev nyiam noj zaub mov. Li no thaum kev noj haus yog ib qho kev txiav txim siab tseem ceeb heev rau tus neeg mob qog noj ntshav thiab tus neeg muaj kev pheej hmoo ntawm mob qog noj ntshav - yuav ua li cas xaiv cov zaub mov noj tsis yog ib txoj haujlwm yooj yim.

Rau Ovarian Cancer nws puas muaj teeb meem dab tsi zaub, txiv hmab txiv ntoo, txiv ntoo, noob noj?

Cov lus nug txog kev noj zaub mov ntau ntau nug los ntawm cov neeg mob qog noj ntshav thiab cov tib neeg uas muaj kev pheej hmoo ntawm qog noj ntshav yog - rau cov qog nqaij hlav xws li Ovarian Cancer nws puas tseem ceeb cov zaub mov kuv noj thiab qhov kuv tsis ua? Los yog yog tias kuv ua raws li kev noj zaub mov zoo yog qhov txaus rau mob qog noj ntshav zoo li Ovarian Cancer?

Piv txwv li nws puas tseem ceeb yog tias zaub Cauliflower tau noj ntau dua piv rau Garden Tomato? Nws puas muaj qhov txawv yog tias txiv hmab txiv ntoo Dub Elderberry nyiam dua Pomegranate? Tsis tas li yog tias cov kev xaiv zoo sib xws tau tsim rau cov txiv ntoo / cov noob zoo li Butternut hla Brazil Nut thiab rau pulses zoo li Broad Bean tshaj Chickpea. Thiab yog tias kuv noj dab tsi tseem ceeb - ces yuav ua li cas thiaj paub cov zaub mov uas pom zoo rau Ovarian Cancer thiab nws puas yog tib lo lus teb rau txhua tus neeg uas muaj tib yam kev kuaj mob lossis kev pheej hmoo ntawm caj ces?

Yog lawm! Cov zaub mov koj noj tseem ceeb rau Ovarian Cancer!

Cov lus pom zoo yuav tsis zoo ib yam rau txhua tus thiab tuaj yeem sib txawv txawm tias tib yam kev kuaj mob thiab kev pheej hmoo ntawm caj ces.

Txhua yam khoom noj ( zaub, txiv hmab txiv ntoo, txiv ntseej, noob, pulses, roj thiab lwm yam) thiab cov khoom noj khoom haus yog tsim los ntawm ntau tshaj ib qho khoom xyaw molecular lossis bio-actives nyob rau hauv sib txawv proportions thiab ntau npaum. Txhua yam khoom muaj txiaj ntsig muaj qhov tshwj xeeb ntawm kev ua haujlwm - uas tuaj yeem ua kom ua haujlwm lossis inhibition ntawm ntau txoj hauv kev biochemical. Cov zaub mov uas yooj yim hais thiab cov tshuaj uas tau pom zoo yog cov uas tsis ua rau muaj kev nce ntxiv ntawm molecular tsav mob qog noj ntshav tab sis txo lawv. Lwm cov zaub mov no yuav tsum tsis pom zoo. Cov khoom noj muaj ntau yam khoom xyaw - yog li thaum ntsuas cov khoom noj thiab tshuaj ntxiv koj yuav tsum xav txog qhov cuam tshuam ntawm tag nrho cov khoom xyaw nquag ua ke ntau dua li ntawm tus kheej.

Piv txwv li Black Elderberry muaj cov khoom xyaw nquag Lycopene, Curcumin, Isoliquiritigenin, Quercetin, Myricetin. Thiab Pomegranate muaj cov khoom xyaw nquag Curcumin, Isoliquiritigenin, Quercetin, Myricetin, Naringin thiab tej zaum lwm tus.

Ib qho yuam kev uas tau ua thaum txiav txim siab thiab xaiv cov zaub mov noj rau Ovarian Cancer - yog ntsuas tsuas yog xaiv cov khoom xyaw uas muaj nyob hauv cov zaub mov thiab tsis quav ntsej lwm tus. Vim tias cov khoom xyaw sib txawv uas muaj nyob hauv cov zaub mov yuav muaj kev cuam tshuam rau cov neeg mob qog noj ntshav - koj tuaj yeem tsis tuaj yeem xaiv cov khoom xyaw nquag hauv cov zaub mov thiab tshuaj ntxiv rau kev txiav txim siab noj zaub mov rau Ovarian Cancer.

YOG – KEV PAB CUAM TSHUAJ RAU QHOV TSEEB. Kev txiav txim siab txog kev noj zaub mov yuav tsum xav txog txhua yam khoom muaj txiaj ntsig ntawm cov khoom noj.

Kev txawj xav tau kev noj haus Personalization rau Ovarian Cancer?

Khoom noj khoom haus tus kheej rau cov qog nqaij hlav xws li Ovarian Cancer muaj cov zaub mov pom zoo / tshuaj ntxiv; tsis pom zoo cov zaub mov / tshuaj ntxiv nrog piv txwv cov zaub mov txawv uas ua ntej siv cov khoom noj pom zoo. Ib qho piv txwv ntawm kev noj zaub mov tus kheej tuaj yeem pom ntawm qhov no txuas.

Kev txiav txim siab seb cov zaub mov twg raug pom zoo lossis tsis yog qhov nyuaj heev, yuav tsum muaj kev txawj ntse hauv Ovarian Cancer biology, kev tshawb fawb txog zaub mov, noob caj noob ces, biochemistry nrog rau kev nkag siab zoo txog kev kho mob qog noj ntshav ua haujlwm li cas thiab cuam tshuam qhov tsis zoo uas cov kev kho mob tuaj yeem nres tau zoo.

QHOV TSEEB TSEEM CEEB TSHAJ PLAWS YUAV TSUM TAU TXAIS KEV PHEM NTAWM KEV KAWM NTAWV THOV KEV PAB CUAM yog: Kev Kho Mob BIOLOGY, FOOD SCIENCE, Kev Kho Mob Cancer thiab GENETICS.

Cov yam ntxwv ntawm cov qog nqaij hlav xws li Ovarian Cancer

Tag nrho cov qog nqaij hlav xws li Ovarian Cancer tuaj yeem ua tus cwj pwm los ntawm cov txheej txheem biochemical - txoj kev kos npe ntawm Ovarian Cancer. Txoj hauv kev biochemical zoo li Inflamation, NFKB Signaling, Cell Cycle Checkpoints, Apoptosis yog ib feem ntawm kos npe txhais ntawm Ovarian Cancer. Txhua tus neeg tus kab mob qog noj ntshav tuaj yeem sib txawv thiab yog li lawv qhov tshwj xeeb kos npe mob qog noj ntshav yuav txawv.

Cov kev kho mob uas muaj txiaj ntsig zoo rau Ovarian Cancer yuav tsum paub txog cov txheej txheem kev kos npe biochemical rau txhua tus neeg mob qog noj ntshav thiab ib tus neeg muaj kev pheej hmoo ntawm caj ces. Yog li kev kho mob sib txawv nrog cov txheej txheem sib txawv ntawm kev ua haujlwm zoo rau cov neeg mob sib txawv. Ib yam li ntawd thiab rau tib lub laj thawj khoom noj thiab tshuaj ntxiv yuav tsum tau ua tus kheej rau txhua tus neeg. Li no, qee cov zaub mov thiab tshuaj ntxiv tau pom zoo rau Ovarian Cancer thaum noj tshuaj kho mob qog noj ntshav Olaparib, thiab qee cov zaub mov thiab tshuaj tsis pom zoo.

Qhov chaw zoo li cBioPortal thiab ntau lwm tus muab cov neeg sawv cev ntawm tus neeg mob tsis qhia npe cov ntaub ntawv los ntawm kev sim tshuaj rau txhua qhov qhia txog mob qog noj ntshav. Cov ntaub ntawv no muaj cov ntaub ntawv tshawb fawb soj ntsuam xws li tus qauv loj / tus naj npawb ntawm cov neeg mob, pawg hnub nyoog, poj niam txiv neej, haiv neeg, kev kho mob, qog qhov chaw thiab txhua yam kev hloov caj ces.

TP53, MUC16, NF1, RYR2 thiab KMT2C yog cov npe saum toj kawg nkaus tshaj tawm cov noob rau Ovarian Cancer. TP53 tau tshaj tawm hauv 29.2% ntawm cov neeg sawv cev ntawm cov neeg mob thoob plaws txhua qhov kev sim tshuaj. Thiab MUC16 tau tshaj tawm hauv 3.2%. Cov ntaub ntawv qhia cov neeg mob ua ke suav nrog hnub nyoog ntawm 26 txog 89. 0.0% ntawm cov ntaub ntawv tus neeg mob raug txheeb xyuas tias yog txiv neej. Ovarian Cancer biology nrog rau kev tshaj tawm cov noob caj noob ces ua ke txhais cov pej xeem sawv cev rau kev kos npe biochemical rau tus kabmob no. Yog hais tias tus neeg mob qog nqaij hlav qog nqaij hlav caj ces lossis cov caj ces ua rau muaj kev pheej hmoo kuj paub, qhov ntawd yuav tsum tau siv rau kev noj zaub mov tus kheej.

Kev xaiv noj zaub mov yuav tsum sib phim nrog txhua tus tib neeg tus CANCER kos npe.

Khoom noj khoom haus thiab ntxiv rau Ovarian Cancer

Rau Cov Neeg Mob Cancer

Cov neeg mob qog noj ntshav ntawm kev kho mob lossis kev kho mob palliative yuav tsum tau txiav txim siab txog zaub mov thiab tshuaj ntxiv - rau cov calories uas xav tau kev noj haus, rau kev tswj hwm cov kev mob tshwm sim thiab kev kho mob qog noj ntshav. Tag nrho cov khoom noj uas muaj cov nroj tsuag tsis sib npaug thiab xaiv thiab saib xyuas cov khoom noj uas yog tus kheej thiab kho rau kev kho mob qog noj ntshav tsis tu ncua yog qhov tseem ceeb thiab nyuaj. Nov yog qee qhov piv txwv muab cov lus qhia rau kev txiav txim siab noj zaub mov.

Xaiv Zaub CAULIFLOWER lossis GARDEN TOMATO?

Zaub Cauliflower muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Isoliquiritigenin, Cinnamaldehyde, Psoralen, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li Inflammation, MAPK Signaling, TWEAK Signaling thiab MYC Signaling thiab lwm yam. Cauliflower raug pom zoo rau Ovarian Cancer thaum kho mob qog noj ntshav tsis tu ncua yog Olaparib. Qhov no yog vim Cauliflower hloov cov txheej txheem biochemical uas tau raug tshawb fawb qhia los ua kom cov nyhuv ntawm Olaparib.

Qee cov khoom xyaw nquag lossis bioactives hauv zaub Garden Txiv lws suav yog Lycopene, Curcumin, Isoliquiritigenin, Quercetin, Myricetin. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical zoo li DNA Kho thiab lwm yam. Garden Txiv lws suav tsis pom zoo rau Ovarian Cancer thaum kho mob qog noj ntshav tsis tu ncua yog Olaparib vim tias nws hloov kho cov txheej txheem biochemical uas ua rau kev kho mob qog noj ntshav tsis zoo lossis tsis teb.

Zaub CAULIFLOWER tau pom zoo tshaj GARDEN TOMATO rau Ovarian Cancer thiab kho Olaparib.

Xaiv Txiv Hmab Txiv Ntoo POMEGRANATE los yog BLACK ELDERBERRY?

Txiv Hmab Txiv Ntoo Pomegranate muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Isoliquiritigenin, Quercetin, Myricetin, Naringin. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li DNA Kho, Epithelial mus rau Mesenchymal Hloov, Inflammation thiab MAPK Signaling thiab lwm yam. Pomegranate pom zoo rau Ovarian Cancer thaum kho mob qog noj ntshav tsis tu ncua yog Olaparib. Qhov no yog vim Pomegranate hloov kho cov txheej txheem biochemical uas tau tshaj tawm tshawb fawb los ua kom muaj txiaj ntsig ntawm Olaparib.

Qee cov khoom xyaw nquag lossis bioactives hauv cov txiv hmab txiv ntoo Dub Elderberry yog Lycopene, Curcumin, Isoliquiritigenin, Quercetin, Myricetin. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li DNA Kho thiab MAPK Signaling thiab lwm yam. Dub Elderberry tsis pom zoo rau Ovarian Cancer thaum kho mob qog noj ntshav tsis tu ncua yog Olaparib vim nws hloov kho cov txheej txheem biochemical uas ua rau kev kho mob qog noj ntshav tsis zoo lossis tsis teb.

Txiv Hmab Txiv Ntoo POMEGRANATE yog pom zoo tshaj dub ELDERBERRY rau Ovarian Cancer thiab kho Olaparib.

Xaiv txiv ntseej BUTTERNUT lossis BRAZIL NUT?

Butternut muaj ntau yam khoom xyaw lossis bioactives xws li Lycopene, Curcumin, Isoliquiritigenin, Myricetin, Caffeine. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li DNA Kho, Epithelial mus rau Mesenchymal Hloov, Inflammation thiab MAPK Signaling thiab lwm yam. Butternut raug pom zoo rau Ovarian Cancer thaum kho mob qog noj ntshav tsis tu ncua yog Olaparib. Qhov no yog vim Butternut hloov cov txheej txheem biochemical uas tau tshaj tawm tshawb fawb los ua kom cov nyhuv ntawm Olaparib.

Qee cov khoom xyaw nquag lossis bioactives hauv Brazil txiv ntoo yog Curcumin, Isoliquiritigenin, Cinnamaldehyde, Psoralen, Ellagic Acid. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li Epithelial mus rau Mesenchymal Hloov, Inflamation thiab TWEAK Signaling thiab lwm yam. Brazil txiv ntoo tsis pom zoo rau Ovarian Cancer thaum kho mob qog noj ntshav tsis tu ncua yog Olaparib vim tias nws hloov kho cov txheej txheem biochemical uas ua rau kev kho mob qog noj ntshav tsis zoo lossis tsis teb.

BUTTERNUT tau pom zoo tshaj BRAZIL NUT rau Ovarian Cancer thiab kho Olaparib.

Rau cov tib neeg uas muaj kev pheej hmoo ntawm mob qog noj ntshav

Cov lus nug nug los ntawm cov tib neeg uas muaj kev pheej hmoo ntawm caj ces ntawm Ovarian Cancer los yog tsev neeg keeb kwm yog "Kuv Yuav Tsum Noj Dab Tsi Ntawm Qhov Ua Ntej?" thiab yuav ua li cas lawv yuav tsum xaiv cov zaub mov thiab cov tshuaj ntxiv los tswj kev pheej hmoo ntawm tus kab mob. Txij li thaum muaj kev pheej hmoo mob qog noj ntshav tsis muaj ib yam dab tsi ua tau raws li kev kho mob - kev txiav txim siab ntawm cov khoom noj thiab tshuaj ntxiv ua ib qho tseem ceeb thiab ib qho ntawm ob peb yam uas yuav ua tau. Tag nrho cov khoom noj uas cog tsis sib npaug thiab raws li cov noob caj noob ces thiab kev kos npe - cov kev xaiv ntawm cov khoom noj thiab cov tshuaj yuav tsum yog tus kheej.

Xaiv Zaub KALE lossis AMERICAN POKEWEED?

Zaub Kale muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Lupeol, Indole-3-carbinol, Daidzein, Formononetin. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li DNA Kho, Cell Cycle, MAPK Signaling thiab MYC Signaling thiab lwm yam. Kale tau pom zoo rau kev pheej hmoo ntawm Ovarian Cancer thaum muaj kev pheej hmoo ntawm caj ces yog KMT2C. Qhov no yog vim Kale nce cov kab mob biochemical uas tawm tsam cov neeg tsav tsheb kos npe ntawm nws.

Qee cov khoom xyaw nquag lossis bioactives hauv zaub American Pokeweed yog Apigenin, Curcumin, Lupeol, Quercetin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li DNA Kho thiab MAPK Signaling thiab lwm yam. American Pokeweed tsis pom zoo thaum muaj kev pheej hmoo ntawm Ovarian Cancer thaum muaj kev pheej hmoo ntawm caj ces yog KMT2C vim tias nws nce txoj hauv kev kos npe ntawm nws.

Cov zaub KALE tau pom zoo tshaj AMERICAN POKEWEED rau KMT2C genetic Risk ntawm CANCER.

Xaiv txiv hmab txiv ntoo liab RASPBERRY los yog PUMMELO?

Txiv Hmab Txiv Ntoo Liab Raspberry muaj ntau yam khoom xyaw lossis bioactives xws li Curcumin, Ellagic Acid, Lupeol, Quercetin, Daidzein. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li Cell Cycle, P53 Signaling, DNA Kho thiab MYC Signaling thiab lwm yam. Liab Raspberry raug pom zoo rau kev pheej hmoo ntawm Ovarian Cancer thaum muaj kev pheej hmoo ntawm caj ces yog KMT2C. Qhov no yog vim Red Raspberry tsub kom cov biochemical pathways uas counteract tus kos npe tsav tsheb ntawm nws.

Qee cov khoom xyaw nquag lossis bioactives hauv txiv hmab txiv ntoo Pummelo yog Apigenin, Curcumin, Lupeol, Lycopene, Quercetin. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li DNA Kho thiab Extracellular Matrix Remodeling thiab lwm yam. Pummelo tsis pom zoo thaum muaj kev pheej hmoo ntawm Ovarian Cancer thaum muaj kev pheej hmoo ntawm caj ces yog KMT2C vim tias nws nce txoj hauv kev kos npe ntawm nws.

Txiv Hmab Txiv Ntoo Liab RASPBERRY tau pom zoo tshaj PUMMELO rau KMT2C genetic Risk of Cancer.

Xaiv txiv ntseej BLACK WALNUT lossis CHESTNUT?

Black Walnut muaj ntau yam khoom xyaw lossis bioactives xws li Apigenin, Curcumin, Ellagic Acid, Lupeol, Quercetin. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li Cell Cycle, P53 Signaling, MAPK Signaling thiab Cell Cycle Checkpoints thiab lwm yam. Black Walnut raug pom zoo rau kev pheej hmoo ntawm Ovarian Cancer thaum muaj feem cuam tshuam caj ces yog KMT2C. Qhov no yog vim Black Walnut tsub kom cov biochemical txoj kev uas counteract tus kos npe tsav tsheb ntawm nws.

Qee yam khoom xyaw lossis bioactives hauv Chestnut yog Apigenin, Curcumin, Ellagic Acid, Lupeol, Lycopene. Cov khoom xyaw nquag no tswj hwm ntau txoj hauv kev biochemical xws li DNA Kho, Extracellular Matrix Remodeling thiab Cell Cycle Checkpoints thiab lwm yam. Chestnut tsis pom zoo thaum muaj kev pheej hmoo ntawm Ovarian Cancer thaum muaj kev pheej hmoo ntawm caj ces yog KMT2C vim tias nws nce txoj hauv kev kos npe ntawm nws.

BLACK WALNUT tau pom zoo tshaj CHESTNUT rau KMT2C genetic Risk of Cancer.

Nyob rau hauv Xaus

Cov khoom noj thiab cov khoom noj uas tau xaiv yog cov kev txiav txim siab tseem ceeb rau cov qog nqaij hlav xws li Ovarian Cancer. Cov neeg mob qog nqaij hlav zes qe menyuam thiab cov tib neeg uas muaj kev pheej hmoo ntawm caj ces ib txwm muaj lo lus nug no: "Yuav ua li cas cov zaub mov thiab cov khoom noj khoom haus tau pom zoo rau kuv thiab qhov twg tsis yog?" Muaj ib qho kev ntseeg uas yog ib qho kev xav tsis zoo uas txhua yam khoom noj uas cog qoob loo tuaj yeem muaj txiaj ntsig lossis tsis zoo tab sis yuav tsis muaj teeb meem. Qee cov zaub mov thiab tshuaj ntxiv tuaj yeem cuam tshuam nrog kev kho mob qog noj ntshav lossis txhawb nqa txoj hauv kev ntawm cov neeg mob qog noj ntshav.

Muaj ntau hom kab mob qog noj ntshav xws li Ovarian Cancer, txhua tus muaj cov qog nqaij hlav sib txawv nrog cov kev hloov genomic ntxiv rau txhua tus neeg. Ntxiv mus, txhua txoj kev kho mob qog noj ntshav thiab kws khomob muaj qhov tshwj xeeb ntawm kev ua haujlwm. Txhua yam khoom noj xws li Cauliflower muaj ntau yam bioactives nyob rau hauv ntau qhov sib txawv, uas muaj kev cuam tshuam rau kev sib txawv thiab sib txawv ntawm txoj hauv kev biochemical. Lub ntsiab lus ntawm kev noj zaub mov tus kheej yog cov lus pom zoo ntawm tus kheej rau kev mob qog noj ntshav, kev kho mob, caj ces, kev ua neej thiab lwm yam. Kev txiav txim siab noj zaub mov tus kheej rau mob qog noj ntshav xav tau kev paub txog kev mob qog noj ntshav, kev tshawb fawb txog zaub mov thiab kev nkag siab txog kev kho mob sib txawv. Thaum kawg thaum muaj cov kev kho mob hloov pauv lossis cov genomics tshiab raug txheeb xyuas - cov khoom noj khoom haus tus kheej xav tau rov ntsuas dua.

Txoj kev daws teeb meem kev noj haus addon tus kheej ua rau kev txiav txim siab yooj yim thiab tshem tawm tag nrho cov kev kwv yees hauv kev teb cov lus nug, "Kuv yuav tsum xaiv zaub mov dab tsi lossis tsis xaiv rau Ovarian Cancer?". Pab pawg addon ntau txoj kev qhuab qhia suav nrog cov kws kho mob qog noj ntshav, kws tshawb fawb soj ntsuam, software engineers thiab cov kws tshawb fawb cov ntaub ntawv.

References

• Msk Impact 2017
• Pan-cancer tsom xam ntawm tag nrho cov genomes.
• Isoliquiritigenin inhibits Ovarian Cancer Metastasis los ntawm Reversing Epithelial-rau-Mesenchymal Hloov.
• Betulinic Acid Suppresses Breast Cancer Metastasis los ntawm Targeting GRP78-Mediated Glycolysis thiab ER Stress Apoptotic Pathway.
• Gallic acid provokes DNA puas thiab suppresses DNA kho noob qhia nyob rau hauv tib neeg prostate cancer PC-3 hlwb.
• Brassinin inhibits STAT3 kev taw qhia txoj hauv kev los ntawm kev hloov pauv ntawm PIAS-3 thiab SOCS-3 qhia thiab ua rau tib neeg lub ntsws cancer xenograft hauv cov nas liab qab rau paclitaxel.
• Vitamin C xaiv tua KRAS thiab BRAF mutant mob qog noj ntshav los ntawm lub hom phiaj GAPDH.
• Geraniol, ib feem ntawm cov nroj tsuag tseem ceeb roj, sensitizes tib neeg colonic qog nqaij hlav rau 5-Fluorouracil kho.