highlights
Tsis muaj ob yam mob qog noj ntshav zoo ib yam, thiab tsis kho tib yam, thiab tsis tas yuav tsum noj zaub mov zoo ib yam rau txhua tus. Khoom noj khoom haus muaj xws li cov zaub mov xws li pulses, zaub, txiv hmab txiv ntoo, txiv ntseej, roj, tshuaj ntsuab thiab txuj lom. Tsis tas li kev noj haus muaj xws li cov khoom noj uas muaj cov khoom noj muaj txiaj ntsig ntau lossis muaj cov khoom xyaw uas muaj nyob hauv cov khoom noj. Rau cov qog nqaij hlav xws li Ntau Yam Myeloma thaum kho tshuaj khomob lossis thaum koj txiav txim siab tias koj muaj kev pheej hmoo ntawm caj ces rau kev tsim Ntau Yam Myeloma vim yog NRAS thiab BRAF cov noob hloov pauv, cov lus nug tseem ceeb yog "Kuv yuav tsum noj zaub mov dab tsi thiab cov zaub mov twg raug pom zoo rau kuv?" . Lwm cov lus nug ntsig txog yog "Kuv yuav tsum tau noj zaub mov noj dab tsi?".
Tsis muaj leej twg teb rau lo lus nug no rau Cancer xws li Ntau Myeloma uas tuaj yeem nrhiav tau los ntawm kev tshawb fawb hauv internet. Lo lus teb rau lo lus nug yog "Nws nyob ntawm" vim tias txoj kev npaj khoom noj khoom haus yuav tsum yog tus kheej rau koj. Khoom noj khoom haus yuav tsum nyob ntawm seb tus kab mob kheesxaws, cov ntaub ntawv caj ces, cov neeg laus lossis cov menyuam yaus, theem, thawj lossis theem nrab, qib siab, metastatic, rov qab los yog refractory, kev kho tsis tu ncua yog tias muaj, cov khoom noj khoom haus tau noj, hnub nyoog thiab yam xws li poj niam txiv neej, qhov hnyav, qhov siab, kev ua neej. , kev ua xua thiab kev nyiam zaub mov.
Hauv luv luv - cov txheej txheem los teb cov lus nug xws li "Kuv Yuav Tsum Tsis txhob noj txiv hmab txiv ntoo Passion" lossis "Nrog rau cov txiv hmab txiv ntoo Partridgeberry hauv kuv cov zaub mov" lossis "Kuv puas yuav tsum tau txo cov zaub Yam" lossis "Kuv puas tuaj yeem noj Ellagic Acid thiab Dim ntxiv" tsis yog yooj yim li kev tshawb nrhiav hauv internet. Cov txheej txheem yog qhov nyuaj heev thiab cov lus teb yog raws li kev paub txog noob caj noob ces, kev ua ntawm kev kho mob, cov khoom xyaw nquag hauv cov zaub mov thiab lawv cov kev cuam tshuam lom neeg. Thaum kawg, lo lus teb rau lo lus nug khoom noj khoom haus yuav tsum yog tus kheej rau koj.
NYEEM NTXIV: PERSONALIZE koj cov zaub mov thiab cov khoom noj ntxiv rau ntau yam MYELOMA, kev kho mob, genetic info, thiab lwm yam mob.
Lub hom phiaj tag nrho ntawm kev noj zaub mov tus kheej rau Ntau Yam Myeloma yog kom txo qis cov khoom noj thiab cov khoom noj khoom haus uas muaj kev cuam tshuam tsis zoo rau cov neeg mob qog noj ntshav thiab kev kho mob tsis tu ncua. Thiab txheeb xyuas cov khoom noj thiab tshuaj ntxiv uas muaj txiaj ntsig zoo. Thaum twg muaj kev hloov pauv hauv kev kho mob lossis kev kuaj mob - nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias koj cov khoom noj thiab cov tshuaj yuav tsum tau rov ntsuam xyuas dua. Thiab cov lus teb rau lo lus nug khoom noj khoom haus yuav txawv raws li cov ntsiab lus tshiab.
NYEEM NTXIV: Hloov kho koj cov khoom noj khoom haus rau ntau yam MYELOMA, thaum kho, kab mob thiab lwm yam kev hloov pauv.
Txog Ntau Myeloma
cBioPortal yog ib qhov chaw sau los ntawm cancer Cov ntaub ntawv tus neeg mob los ntawm kev sim tshuaj thoob plaws 350 ntxiv rau cov kab mob qog noj ntshav. Cov ntaub ntawv los ntawm txhua qhov kev sim tshuaj suav nrog lub npe tshuaj ntsuam xyuas thiab kev tshawb fawb cov ntsiab lus xws li tus naj npawb ntawm cov neeg mob, hnub nyoog, poj niam txiv neej, haiv neeg, kev kho mob, qog qhov chaw, caj ces aberrations pom thiab tshuaj xyuas tag nrho cov ntaub ntawv. Lub cBioPortal rau Cancer Genomics yog thawj zaug tsim ntawm Memorial Sloan Kettering Cancer Center (MSK). Cov pej xeem cBioPortal site yog tuav los ntawm Lub Chaw rau Molecular Oncology ntawm MSK - https://www.cbioportal.org/about.
Cov ntsiab lus tseem ceeb hauv qab no yog muab los ntawm cov ntaub ntawv kho mob rau Ntau Yam Myeloma los ntawm cBioPortal. Cov neeg mob cuv npe hauv cov kev tshawb fawb rau Ntau Tus Myeloma muaj hnub nyoog li ntawm 24 txog 82 xyoo nrog lub hnub nyoog nruab nrab ntawm 61. 66.2% ntawm cov txiv neej thiab 33.8% ntawm cov poj niam yog qhov faib ntawm poj niam txiv neej hauv cov kev tshawb fawb soj ntsuam. Los ntawm tus neeg mob tus qauv loj ntawm 212; Cov noob saum toj kawg nkaus nrog kev hloov pauv thiab lwm yam txawv txav rau Ntau Yam Myeloma suav nrog cov noob KRAS, NRAS, TP53, BRAF thiab MUC16. Qhov tshwm sim zaus faib rau cov noob no feem yog 22.0%, 18.0%, 7.3%, 6.3% thiab 6.3%. Cov qog caj ces cov ntsiab lus ntawm Ntau Myeloma yog mapped rau molecular biochemical txoj kev tsav tsheb ntawm mob qog noj ntshav yog li muab cov ntsiab lus ntawm cov yam ntxwv ntawm Ntau Myeloma.
Ntau myeloma yog cov qog ntshav ntshav ntawm cov ntshav plasma pom nyob rau hauv cov pob txha pob txha, cov ntaub so ntswg hauv peb cov pob txha, uas feem ntau tsim cov khoom sib txawv ntawm peb cov ntshav. Plasma cells yog ib feem tseem ceeb ntawm lub cev tiv thaiv kab mob. Lawv tsim cov tshuaj tiv thaiv uas pab lub cev tiv thaiv kab mob. Myeloma pib thaum noj qab haus huv plasma hlwb hloov thiab loj hlob ntawm kev tswj. Qhov no yuav ua rau muaj ntau yam pob txha uas ua rau muaj kev pheej hmoo ntawm pob txha pob txha, yog li hu ua ntau yam myeloma. Cov kab mob ntshav plasma txawv txav uas sib faib sai tuaj yeem tawm mus los yog cuam tshuam kev loj hlob ntawm lwm cov hlwb hauv cov pob txha, suav nrog cov qe ntshav liab, cov qe ntshav dawb thiab platelets. Qhov no tsis tsuas yog txo qis lub cev tiv thaiv kab mob, tab sis kuj tuaj yeem ua rau cov ntshav liab los ntawm qhov tsis txaus ntawm cov qe ntshav liab, los ntshav ntau dhau nrog kev txiav me me thiab qhov txhab vim qhov tsis txaus ntawm cov platelets, thiab muaj peev xwm tiv thaiv kab mob, los ntawm qhov tsis txaus ntawm cov qe ntshav dawb. . Myeloma hlwb tsis tuaj yeem tsim cov tshuaj tiv thaiv ua haujlwm tab sis hloov ua M protein uas tuaj yeem tsim hauv cov ntshav thiab zis, uas ua rau lub raum thiab lwm yam kabmob ua rau lub cev tsis zoo, dua li txo kev tiv thaiv kab mob. Ib tus neeg noj qab haus huv uas pom tias muaj me me ntawm cov protein M tau hais tias muaj monoclonal gammopathy ntawm qhov tsis muaj qhov tseem ceeb (MGUS), qhov ua ntej rau ntau yam myeloma.
Kwv yees cov mob tshiab ntawm ntau yam myeloma hauv 2022 yog tshaj 30,000, kwv yees li 1.8% ntawm tag nrho cov mob qog noj ntshav tshiab. Qhov kev muaj sia nyob 5 xyoos rau cov neeg mob uas muaj ntau yam myeloma yog li 58% (Ref: seer.cancer.gov). Kev kho mob rau ntau yam myeloma suav nrog kev kho mob los tswj tus kab mob nrog rau kev txhawb nqa kev txhim kho lub neej zoo, xws li los ntawm kev txo cov tsos mob thiab tswj kev noj qab haus huv zoo nrog cov zaub mov zoo thiab cov khoom siv ntuj tsim. Txoj kev kho mob muaj xws li induction therapy rau kev ceev ceev ntawm cov qog nqaij hlav; consolidation therapy nrog ntau chemotherapy los yog cov pob txha pob txha / qia cell hloov thiab kev kho mob nyob rau lub sij hawm ntev los tiv thaiv kev mob qog noj ntshav. Cov kev kho mob muaj xws li chemotherapy, lub hom phiaj kho, tshuaj immunomodulatory, steroids, tshuaj kho pob txha, thiab immunotherapy. Cov zaub mov zoo thiab cov khoom siv ntuj tsim ua raws li kev kho mob tuaj yeem pab txhim kho tus neeg mob txoj kev noj qab haus huv. (Ref: https://www.cancer.net/cancer-types/multiple-myeloma/introduction; https://www.cancer.org/cancer/multiple-myeloma/about/key-statistics.html)
Qhov tseem ceeb ntawm Kev Noj Qab Haus Huv rau Ntau Yam Myeloma
Tag nrho cov khoom noj thiab cov khoom noj khoom haus muaj xws li kev sau ntawm ib lossis ntau dua cov khoom xyaw tshuaj lom neeg hauv ntau qhov sib txawv thiab ntau. Kev ua ntawm qee cov khoom xyaw nquag hauv cov zaub mov tuaj yeem muaj kev cuam tshuam tsis zoo thaum lwm cov khoom xyaw nquag hauv tib cov zaub mov tuaj yeem txhawb nqa los ntawm cov ntsiab lus ntawm Ntau Myeloma. Yog li ntawd, tib cov zaub mov muaj qhov ua tau zoo thiab tsis zoo thiab kev soj ntsuam ntawm kev sib xyaw ua ke yuav xav tau los ua tus kheej txoj kev npaj khoom noj khoom haus.
Piv txwv li Passion Fruit suav nrog cov khoom xyaw nquag Vitamin C, Oleic Acid, Linolenic Acid, Linoleic Acid, Vitamin A thiab lwm yam. Thiab Partridgeberry muaj cov khoom xyaw nquag Resveratrol, Beta-sitosterol, Stigmasterol thiab lwm yam. Nws yog qhov zoo li tias qee cov khoom xyaw nquag ntawm tib cov zaub mov tuaj yeem muaj qhov cuam tshuam tsis zoo thiab yog li nws raug pom zoo kom txheeb xyuas cov zaub mov pom zoo raws li kev txheeb xyuas ntawm tag nrho cov khoom xyaw uas muaj ntau hauv cov khoom noj.
Rau cov qog nqaij hlav xws li Ntau Yam Myeloma, kev ua kom lossis inhibition ntawm txoj kev xaiv biochemical xws li Growth Factor Signaling, Extracellular Matrix Remodelling, RAS-RAF Signaling, MAPK Signaling plays lub luag haujlwm tseem ceeb hauv kev tsav mob qog noj ntshav. Ib yam li kev kho mob sib txawv ua haujlwm los ntawm kev ua haujlwm molecular sib txawv uas yuav tsum tsis txhob muab tso tseg los ntawm koj cov khoom noj thiab tshuaj ntxiv. Cov khoom noj thiab cov khoom noj khoom haus muaj cov khoom xyaw sib txawv ntawm txhua tus uas muaj cov tshuaj molecular tshwj xeeb ntawm ntau txoj hauv kev biochemical. Yog li, noj qee yam zaub mov thiab khoom noj khoom haus yuav raug pom zoo nrog kev kho mob ntawm Ntau Yam Myeloma, thaum noj lwm yam khoom noj thiab tshuaj ntxiv yuav tsis raug pom zoo.
Ib qho yuam kev thaum nrhiav zaub mov noj lossis tsis yog - tsuas yog xav txog ob peb yam khoom xyaw uas muaj nyob hauv cov khoom noj raws li kev tshawb fawb hauv internet thiab tsis quav ntsej lwm tus. Vim tias cov khoom xyaw sib txawv uas muaj nyob rau hauv cov zaub mov tuaj yeem muaj qhov cuam tshuam rau txoj hauv kev biochemical - nws raug pom zoo kom xav txog tag nrho cov khoom xyaw nquag uas muaj nyob hauv qhov tseem ceeb thiab ntau dua li cov kab hauv cov khoom noj.
NYEEM NTXIV: Nrhiav cov khoom noj uas pom zoo thiab tsis pom zoo rau ntau yam MYELOMA - xav txog ntau yam khoom muaj txiaj ntsig muaj nyob hauv cov zaub mov.
Cov Khoom Noj rau Ntau Yam Myeloma tab tom kho cov kws khomob
Hauv Ntau Yam Myeloma - cov noob KRAS, NRAS, TP53, BRAF thiab MUC16 muaj qhov tshwm sim loj ntawm genomic txawv txav. Tsis yog tag nrho cov noob no yuav tsum muaj feem cuam tshuam rau cancer - txawm tias lawv tau tshaj tawm. Qee yam ntawm cov noob no ncaj qha lossis ncaj qha mus rau kev tswj xyuas cov qog nqaij hlav sib txawv ntsig txog biochemical biological pathways. Qee txoj hauv kev uas muaj feem cuam tshuam rau kev tsav tsheb ntau yam Myeloma yog Growth Factor Signaling, Extracellular Matrix Remodelling, Angiogenesis thiab lwm yam. Bortezomib yog ib qho ntawm cov kws khomob siv rau kev kho mob qog noj ntshav. Lub hom phiaj ntawm kev kho mob yog kom tsis pom zoo los yog tshem tawm cov teebmeem ntawm biochemical txoj kev tsav tsheb Growth Factor Signaling, Extracellular Matrix Remodelling, Angiogenesis thiaj li txo cov kab mob thiab inhibit kev loj hlob. Cov khoom noj uas muaj kev sib xyaw ua ke ntawm cov khoom xyaw nquag txhawb kev kho mob thiab tsis txhim kho tus kab mob tsav tsheb yog cov zaub mov pom zoo thiab cov tshuaj ntxiv uas yuav suav nrog hauv cov khoom noj ntawm tus kheej. Thiab zoo ib yam - cov khoom noj uas ua ke ntawm cov khoom xyaw ua ke tsis txhawb nqa kev kho mob tab sis xaus rau kev txhawb nqa kab mob yuav tsis raug pom zoo hauv koj txoj kev npaj zaub mov noj.
TSEEM CEEB: Tsis txhob noj cov tshuaj ntxiv thiab cov zaub mov uas tsis txhawb nqa kev kho mob qog noj ntshav thiab ua rau muaj txiaj ntsig zoo rau tus neeg mob.
Noj ntau pulses, Black-eyed Pea los yog Pigeon Pea?
Pulses yog ib feem tseem ceeb ntawm ntau yam khoom noj. Cov khoom xyaw nquag muaj nyob hauv Black-eyed Pea yog Vitamin C, Daidzein, Oleic Acid, Linolenic Acid, Beta-carotene thiab lwm yam. Thaum cov khoom xyaw nquag muaj nyob hauv Pigeon Pea yog Vitamin C, Oleic Acid, Linolenic Acid, Genistein, Linoleic Acid thiab lwm yam.
Vitamin C tuaj yeem tswj hwm txoj hauv kev biochemical WNT Beta Catenin Signaling, Angiogenesis thiab Hypoxia. Daidzein muaj cov tshuaj lom neeg ntawm biochemical txoj hauv kev PI3K-AKT-MTOR Kev Qhia Tawm, Oxidative Stress thiab Endoplasmic Reticulum Stress.
Genistein tuaj yeem tswj xyuas biochemical txoj hauv kev Oxidative Stress. Vitamin A muaj cov tshuaj lom neeg ntawm biochemical pathways Extracellular Matrix Remodeling. Thiab li ntawd.
Thaum kho Ntau Myeloma nrog tshuaj kho Bortezomib - Cov khoom noj xws li Black-eyed Pea tau pom zoo muab piv rau Pigeon Pea. Qhov no yog vim hais tias cov khoom xyaw nquag Genistein thiab Vitamin A hauv Pigeon Pea cuam tshuam nrog kev kho mob los ntawm kev tshem tawm cov txheej txheem biochemical los ntawm kev siv tshuaj khomob. Thaum cov khoom xyaw nquag vitamin C thiab Daidzein muaj nyob rau hauv Black-eyed Pea txhawb txoj kev kho mob los ntawm kev txhim kho cov kab mob biochemical los ntawm kev siv tshuaj khomob.
NYEEM NTXIV: BLACK-EYED PEA tau pom zoo tshaj PIGEON PEA rau ntau yam MYELOMA ntawm kev kho nrog CHEMOTHERAPY BORTEZOMIB rau qee yam mob.
Noj zaub ntau dua, Giant Butterbur lossis Yam?
Zaub yog ib qho tseem ceeb ntawm ntau yam khoom noj. Cov khoom xyaw nquag muaj nyob hauv Giant Butterbur yog Vitamin C, Melatonin, Beta-sitosterol, Kaempferol, Vitamin A thiab lwm yam. Thaum cov khoom xyaw nquag muaj nyob hauv Yam yog Vitamin C, Beta-sitosterol, Oleic Acid, Linolenic Acid, Dioscin thiab lwm yam.
Vitamin C tuaj yeem tswj hwm txoj hauv kev biochemical WNT Beta Catenin Signaling, Angiogenesis thiab Hypoxia. Melatonin muaj cov tshuaj lom neeg ntawm biochemical txoj hauv kev PI3K-AKT-MTOR Kev Tshaj Tawm, Kev Loj Hlob Factor Signaling thiab Oxidative Stress.
Citric Acid tuaj yeem tswj hwm txoj hauv kev biochemical Oxidative Stress. Dioscin muaj cov tshuaj lom neeg ntawm biochemical pathways Notch Signaling. Thiab li ntawd.
Thaum kho Ntau Myeloma nrog tshuaj kho Bortezomib - Cov khoom noj zoo li Giant Butterbur tau pom zoo muab piv rau Yam. Qhov no yog vim hais tias cov khoom xyaw nquag Citric Acid thiab Dioscin hauv Yam cuam tshuam nrog kev kho mob los ntawm kev tshem tawm cov txheej txheem biochemical los ntawm kev siv tshuaj khomob. Thaum cov khoom xyaw nquag vitamin C thiab Melatonin muaj nyob rau hauv Giant Butterbur txhawb txoj kev kho mob los ntawm kev txhim kho cov kab mob biochemical los ntawm kev siv tshuaj khomob.
NYEEM NTXIV: GIANT ButterBUR tau pom zoo los ntawm YAM rau ntau yam MYELOMA ntawm kev kho nrog CHEMOTHERAPY BORTEZOMIB rau qee yam mob.
Txuas mus rau MySQL tsis tau: Tsis muaj txoj hauv kev los tuav
Noj ntau txiv hmab txiv ntoo, Partridgeberry lossis Passion Fruit?
Txiv hmab txiv ntoo yog ib feem tseem ceeb ntawm ntau yam khoom noj. Cov khoom xyaw nquag muaj nyob rau hauv Partridgeberry yog Resveratrol, Beta-sitosterol, Stigmasterol thiab lwm yam. Thaum cov khoom xyaw nquag muaj nyob rau hauv Passion Fruit yog Vitamin C, Oleic Acid, Linolenic Acid, Linoleic Acid, Vitamin A thiab lwm yam.
Resveratrol tuaj yeem tswj hwm txoj hauv kev biochemical Hypoxia, Angiogenesis thiab Endoplasmic Reticulum Stress. Beta-sitosterol muaj cov tshuaj lom neeg ua haujlwm ntawm biochemical pathways WNT Beta Catenin Signaling, PI3K-AKT-MTOR Kev Qhia thiab Oxidative Stress.
Vitamin A tuaj yeem tswj cov txheej txheem biochemical Extracellular Matrix Remodeling. Citric Acid muaj cov tshuaj lom neeg ntawm biochemical txoj hauv kev Oxidative Stress. Thiab li ntawd.
Thaum kho Ntau Myeloma nrog tshuaj kho Bortezomib - Cov khoom noj zoo li Partridgeberry raug pom zoo piv rau Passion Fruit. Qhov no yog vim hais tias cov khoom xyaw nquag Vitamin A thiab Citric Acid hauv Passion Fruit cuam tshuam nrog kev kho mob los ntawm kev tshem tawm cov txheej txheem biochemical los ntawm kev siv tshuaj khomob. Thaum cov khoom xyaw nquag Resveratrol thiab Beta-sitosterol muaj nyob rau hauv Partridgeberry txhawb txoj kev kho mob los ntawm kev txhim kho cov kab mob biochemical los ntawm kev siv tshuaj khomob.
NYEEM NTXIV: PARTRIDGEBERRY tau pom zoo los ntawm PASSION FRUIT rau ntau MYELOMA ntawm kev kho nrog CHEMOTHERAPY BORTEZOMIB rau qee yam mob.
Noj ntau txiv ntseej, Chestnut lossis Macadamia Nut?
Txiv ntseej yog ib feem tseem ceeb ntawm ntau yam khoom noj. Cov khoom xyaw nquag muaj nyob hauv Chestnut yog Quercetin, Ellagic Acid, Vitamin C, Oleic Acid, Betulin thiab lwm yam. Thaum cov khoom xyaw nquag muaj nyob hauv Macadamia txiv ntoo yog Beta-sitosterol, Lauric Acid, Palmetic Acid, Myristic Acid, Folic Acid thiab lwm yam.
Ellagic Acid tuaj yeem tswj hwm txoj hauv kev biochemical WNT Beta Catenin Signaling, Angiogenesis thiab Extracellular Matrix Remodelling. Betulin muaj cov tshuaj lom neeg ntawm biochemical pathways Hypoxia, Oxidative Stress thiab PI3K-AKT-MTOR Signaling.
Lauric Acid tuaj yeem tswj hwm txoj hauv kev biochemical PI3K-AKT-MTOR Kev Qhia. Palmitic Acid muaj cov tshuaj lom neeg ntawm biochemical pathways WNT Beta Catenin Signaling, Angiogenesis thiab Extracellular Matrix Remodelling. Thiab li ntawd.
Thaum kho Ntau Myeloma nrog cov tshuaj kho mob Bortezomib - Cov khoom noj zoo li Chestnut tau pom zoo piv rau Macadamia Txiv Ntoo. Qhov no yog vim hais tias cov khoom xyaw nquag Lauric Acid thiab Palmitic Acid hauv Macadamia Nut cuam tshuam nrog kev kho mob los ntawm kev tshem tawm cov txheej txheem biochemical los ntawm kev siv tshuaj khomob. Thaum cov khoom xyaw nquag Ellagic Acid thiab Betulin muaj nyob rau hauv Chestnut txhawb txoj kev kho mob los ntawm kev txhim kho cov kab mob biochemical los ntawm kev siv tshuaj khomob.
NYEEM NTXIV: CHESTNUT tau pom zoo tshaj MACADAMIA NUT rau ntau MYELOMA ntawm kev kho nrog CHEMOTHERAPY BORTEZOMIB rau qee yam mob.
Khoom noj khoom haus rau Genetic Risk of Multiple Myeloma
Ib txoj hauv kev los ntsuas kev pheej hmoo ntawm cancer yog los ntawm kev tshuaj xyuas qhov muaj qhov txawv txav ntawm cov noob caj noob ces. Muaj cov ntaub ntawv ua ntej ntawm cov npe ntawm cov noob uas nws hloov pauv thiab lwm yam kev hloov pauv tuaj yeem ua lub luag haujlwm hauv kev pheej hmoo rau cov qog nqaij hlav sib txawv. NRAS thiab BRAF yog ob lub noob uas nws qhov txawv txav yog qhov muaj feem cuam tshuam rau Ntau Yam Myeloma. Nyob rau hauv cov xwm txheej zoo li no muaj kev pheej hmoo mob qog noj ntshav - thaum feem ntau tsis muaj kev kho mob uas tus kws kho mob tuaj yeem sau tau - ntau txoj hauv kev biochemical uas muaj peev xwm tsav tsheb molecular ntawm Ntau Myeloma tuaj yeem siv los ua cov lus qhia rau los nrog kev pom zoo rau kev npaj zaub mov noj. Rau Ntau Myeloma gene NRAS muaj kev cuam tshuam rau kev lom neeg xws li G-protein-coupled Receptor Signaling, Growth Factor Signaling thiab RAS-RAF Signaling. Thiab BRAF muaj qhov ua rau muaj kev cuam tshuam rau txoj hauv kev lom neeg xws li RAS-RAF Signaling, MAPK Signaling thiab Antigen Presentation. Cov khoom noj thiab cov khoom noj khoom haus uas muaj cov tshuaj molecular los tshem tawm cov kab mob biochemical los ntawm cov noob xws li NRAS thiab BRAF yuav tsum suav nrog hauv cov phiaj xwm khoom noj khoom haus tus kheej. Thiab cov zaub mov thiab cov tshuaj ntxiv uas txhawb nqa cov txiaj ntsig ntawm cov noob NRAS thiab BRAF yuav tsum raug zam.
Noj ntau pulses, Mung taum los yog Adzuki taum?
Cov khoom xyaw nquag muaj nyob hauv Mung Bean yog Quercetin, Oleic Acid, Linolenic Acid, Vitamin C, Vitexin thiab lwm yam. Thaum cov khoom xyaw nquag muaj nyob hauv Adzuki Bean yog Isoliquiritigenin, Glucaric Acid, Genistein, Folic Acid thiab lwm yam.
Quercetin tuaj yeem tswj xyuas txoj hauv kev biochemical MAPK Signaling, Cell Cycle Checkpoints thiab RAS-RAF Signaling. Vitamin C muaj cov tshuaj lom neeg ntawm biochemical pathways P53 Signaling, MYC Signaling thiab PI3K-AKT-MTOR Signaling.
Folic Acid tuaj yeem tswj xyuas txoj hauv kev biochemical MAPK Signaling, Cell Cycle Checkpoints thiab RAS-RAF Signaling. Thiab li ntawd.
Rau kev pheej hmoo ntawm caj ces ntawm Ntau Myeloma vim qhov txawv txav ntawm cov noob NRAS thiab BRAF - Cov zaub mov zoo li Mung Bean tau pom zoo piv rau Adzuki Bean. Qhov no yog vim hais tias cov khoom xyaw nquag Folic Acid nyob rau hauv Adzuki Bean ntxiv txhawb kev cuam tshuam ntawm cov noob ntawm txoj kev biochemical. Thaum cov khoom xyaw nquag Quercetin thiab Vitamin C muaj nyob rau hauv Mung Bean ua ke muaj kev tshem tawm cov noob ntawm txoj hauv kev biochemical.
NYEEM NTXIV: MUNG taum tau pom zoo tshaj ADZUKI taum txhawm rau txo qhov kev pheej hmoo ntawm caj ces ntawm ntau MYELOMA vim yog genes NRAS thiab BRAF
Noj zaub ntau dua, Cassava lossis Celery?
Cov khoom xyaw nquag muaj nyob hauv Cassava yog Beta-sitosterol, Oleic Acid, Linolenic Acid, Vitamin C, Linoleic Acid thiab lwm yam. Thaum cov khoom xyaw nquag muaj nyob hauv Celery yog Apigenin, Quercetin, Oleic Acid, Linolenic Acid, Vitamin C thiab lwm yam.
Vitamin C tuaj yeem tswj hwm txoj hauv kev biochemical MAPK Signaling, Cell Cycle Checkpoints thiab RAS-RAF Signaling. Beta-sitosterol muaj cov tshuaj lom neeg ntawm biochemical pathways P53 Signaling, MYC Signaling thiab PI3K-AKT-MTOR Signaling.
Luteolin tuaj yeem tswj hwm txoj hauv kev biochemical MYC Signaling. Chrysin muaj cov tshuaj lom neeg ntawm biochemical txoj hauv kev MYC Signaling. Thiab li ntawd.
Rau kev pheej hmoo ntawm caj ces ntawm Ntau Myeloma vim qhov txawv txav ntawm cov noob NRAS thiab BRAF - Cov zaub mov zoo li Cassava tau pom zoo piv rau Celery. Qhov no yog vim hais tias cov khoom xyaw nquag muaj Luteolin thiab Chrysin hauv Celery ntxiv txhawb cov txiaj ntsig ntawm cov noob ntawm txoj hauv kev biochemical. Thaum cov khoom xyaw nquag Vitamin C thiab Beta-sitosterol muaj nyob rau hauv Cassava ua ke muaj kev tshem tawm cov noob ntawm txoj hauv kev biochemical.
NYEEM NTXIV: CASSAVA tau pom zoo tshaj celery txhawm rau txo qhov kev pheej hmoo ntawm caj ces ntawm ntau yam MYELOMA vim yog genes NRAS thiab BRAF
Cov zaub mov noj tom qab kuaj mob qog noj ntshav!
Tsis muaj ob yam mob qog noj ntshav zoo ib yam. Mus dhau qhov txheej txheem kev noj zaub mov zoo rau txhua tus thiab txiav txim siab tus kheej txog zaub mov thiab tshuaj ntxiv nrog kev ntseeg siab.
Noj ntau txiv hmab txiv ntoo, txiv kab ntxwv los yog Strawberry?
Cov khoom xyaw nquag muaj nyob rau hauv Txiv kab ntxwv yog D-limonene, Linalool, Hloov Citrus Pectin, Oleic Acid, Linolenic Acid thiab lwm yam. Thaum cov khoom xyaw nquag muaj nyob hauv Strawberry yog Ellagic Acid, Lupeol, Cianidanol, Beta-sitosterol, Oleic Acid thiab lwm yam.
D-limonene tuaj yeem tswj xyuas txoj hauv kev biochemical MAPK Signaling, Cell Cycle Checkpoints thiab RAS-RAF Signaling. Vitamin C muaj cov tshuaj lom neeg ntawm biochemical pathways P53 Signaling, MYC Signaling thiab PI3K-AKT-MTOR Signaling.
Fisetin tuaj yeem tswj hwm txoj hauv kev biochemical MYC Signaling. Pelargonidin muaj cov tshuaj lom neeg ntawm biochemical pathways Cell Cycle Checkpoints, PI3K-AKT-MTOR Signaling thiab MYC Signaling. Thiab li ntawd.
Rau kev pheej hmoo ntawm caj ces ntawm Ntau Myeloma vim qhov txawv txav ntawm cov noob NRAS thiab BRAF - Cov khoom noj xws li txiv kab ntxwv tau pom zoo piv rau Strawberry. Qhov no yog vim hais tias cov khoom xyaw nquag Fisetin thiab Pelargonidin hauv Strawberry ntxiv txhawb cov txiaj ntsig ntawm cov noob ntawm txoj hauv kev biochemical. Thaum cov khoom xyaw nquag D-limonene thiab Vitamin C muaj nyob rau hauv Txiv kab ntxwv ua ke muaj kev tshem tawm cov noob ntawm txoj hauv kev biochemical.
NYEEM NTXIV: ORANGE tau pom zoo tshaj STRAWBERRY RAU QHOV CHAW UA HAUJ LWM NTAWM MULTIPLE MYELOMA DUE RAU genes NRAS thiab BRAF
Noj ntau txiv ntoo, Almond lossis Cashew Nut?
Cov khoom xyaw nquag muaj nyob hauv Almond yog Quercetin, Vitamin E, Beta-sitosterol, Oleic Acid, Linolenic Acid thiab lwm yam. Thaum cov khoom xyaw nquag muaj nyob hauv Cashew Nut yog Palmitic Acid, Beta-sitosterol, Vitamin C, Gallic Acid, Butyric Acid thiab lwm yam.
Beta-sitosterol tuaj yeem tswj hwm txoj hauv kev biochemical ntawm Cell Cycle Checkpoints, P53 Signaling thiab MYC Signaling. Quercetin muaj cov tshuaj lom neeg ntawm biochemical pathways MAPK Signaling, RAS-RAF Signaling thiab PI3K-AKT-MTOR Signaling.
Palmetic Acid tuaj yeem tswj xyuas txoj hauv kev biochemical MAPK Signaling. Lauric Acid muaj cov tshuaj lom neeg ntawm biochemical pathways MYC Signaling, PI3K-AKT-MTOR Signaling thiab MAPK Signaling. Thiab li ntawd.
Rau kev pheej hmoo ntawm caj ces ntawm Ntau Myeloma vim qhov txawv txav ntawm cov noob NRAS thiab BRAF - Cov zaub mov zoo li Almond raug pom zoo piv rau Cashew Nut. Qhov no yog vim hais tias cov khoom xyaw nquag Palmetic Acid thiab Lauric Acid hauv Cashew Nut ntxiv txhawb cov txiaj ntsig ntawm cov noob ntawm txoj hauv kev biochemical. Thaum cov khoom xyaw nquag Beta-sitosterol thiab Quercetin muaj nyob rau hauv Almond ua ke muaj kev tshem tawm cov noob ntawm txoj hauv kev biochemical.
NYEEM NTXIV: ALMOND tau pom zoo tshaj cov txiv laum huab xeeb txhawm rau txo cov kev pheej hmoo ntawm caj ces ntawm ntau yam MYELOMA vim yog genes NRAS thiab BRAF
Hauv kev xaus
Ib qho tseem ceeb uas yuav tsum nco ntsoov yog qhov ntawd cancer Cov kev kho mob yuav tsis zoo ib yam rau txhua tus - thiab tsis yog koj cov khoom noj yuav tsum yog. Khoom noj khoom haus uas suav nrog zaub mov thiab khoom noj khoom haus yog ib qho cuab yeej zoo tswj los ntawm koj.
"Kuv yuav tsum noj dab tsi?" yog cov lus nug uas nquag nug hauv cov ntsiab lus ntawm mob qog noj ntshav. Kev suav cov lus teb yog qhov nyuaj thiab nyob ntawm hom mob qog noj ntshav, hauv qab genomics, kev kho mob tam sim no, kev ua xua, cov ntaub ntawv kev ua neej, thiab yam xws li BMI.
Txoj kev npaj khoom noj khoom haus addon tus kheej pom zoo rau cov zaub mov thiab cov tshuaj ntxiv uas txo qis kev cuam tshuam kev noj zaub mov tsis zoo thiab txhawb kev txhawb nqa kev kho mob.
Koj tuaj yeem pib tam sim no thiab tsim cov phiaj xwm kev noj haus tus kheej rau Ntau Yam Myeloma los ntawm kev teb cov lus nug txog hom mob qog noj ntshav, kev kho mob tam sim no, tshuaj ntxiv, kev tsis haum tshuaj, pab pawg hnub nyoog, poj niam txiv neej, thiab cov ntaub ntawv kev ua neej.
Yam zaub mov twg koj noj thiab cov khoom noj uas koj noj yog qhov kev txiav txim siab koj ua. Koj qhov kev txiav txim siab yuav tsum suav nrog kev txiav txim siab ntawm kev hloov pauv noob caj noob ces, uas mob qog noj ntshav, kev kho mob txuas ntxiv thiab tshuaj ntxiv, txhua qhov ua xua, qhia txog kev ua neej nyob, hnyav, qhov siab thiab tus cwj pwm.
Kev npaj zaub mov noj rau mob qog noj ntshav los ntawm addon tsis yog los ntawm kev tshawb fawb hauv internet. Nws siv qhov kev txiav txim siab rau koj raws li kev tshawb fawb molecular siv los ntawm peb cov kws tshawb fawb thiab software engineers. Tsis hais seb koj puas mob siab rau nkag siab cov hauv paus txheej txheem biochemical molecular lossis tsis - rau kev npaj zaub mov noj rau mob qog noj ntshav uas xav tau kev nkag siab.
Pib tam sim no nrog koj cov phiaj xwm kev noj zaub mov zoo los ntawm kev teb cov lus nug ntawm lub npe mob qog noj ntshav, kev hloov pauv caj ces, kev kho mob txuas ntxiv thiab tshuaj ntxiv, txhua yam kev ua xua, tus cwj pwm, lub neej, pab pawg hnub nyoog thiab poj niam txiv neej.
References
- Msk Impact 2017
- Kev nthuav dav genetic heterogeneity nyob rau hauv ntau yam myeloma: cuam tshuam rau kev kho mob.
- Vitamin C xaiv tua KRAS thiab BRAF mutant mob qog noj ntshav los ntawm lub hom phiaj GAPDH.
- Daidzein cov nyhuv ntawm cov tshuaj hormone refractory prostate cancer hauv vitro thiab hauv vivo piv rau genistein thiab soy extract: potentiation ntawm radiotherapy.
- Adhesion rau lub extracellular matrix yog zoo tswj los ntawm retinoic acid nyob rau hauv HepG2 hlwb.
- Resveratrol induces autophagy los ntawm ncaj qha inhibiting mTOR los ntawm kev sib tw ATP.
- β-Sitosterol lub hom phiaj Trx / Trx1 reductase los ntxias apoptosis hauv A549 hlwb ntawm ROS mediated mitochondrial dysregulation thiab p53 activation.
- Melatonin Attenuates Nws-2, p38 MAPK, p-AKT, thiab mTOR Qib hauv Ovarian Carcinoma ntawm Ethanol-Preferring nas.
- Cov nyhuv ntawm dioscin ntawm kev txhawb lub siab rov tsim dua tshiab ntawm kev ua kom Notch1 / Jagged1 teeb liab txoj hauv kev.
- Indeno [1,2-b]indole derivatives raws li cov chav kawm tshiab ntawm cov neeg muaj zog protein kinase CK2 inhibitors.
- Cov tsos mob ntawm congenital mob plawv hauv Dallas County yug. Xyoo 1971-1984.
- Taurine txhim kho qib qis inorganic arsenic-induced insulin tsis kam los ntawm kev ua kom PPARγ-mTORC2 signaling thiab inhibiting hepatic autophagy.
- Protein kinase thiab HDAC inhibitors los ntawm endophytic fungus Epicoccum nigrum.
- Sequential protooncogene qhia nyob rau hauv regenerating raum tom qab mob raum raug mob.
- D-Limonene modulates o, oxidative kev nyuaj siab thiab Ras-ERK txoj kev los inhibit murine daim tawv nqaij hlav.
- Crystal qauv ntawm tib neeg cyclin-dependent kinase 6 complex nrog flavonol inhibitor, fisetin.
- Pelargonidin suppresses adipogenesis nyob rau hauv 3T3-L1 hlwb los ntawm inhibition ntawm PPAR-γ signaling txoj kev.
- Clinical pharmacodynamics ntawm antihistamines.
- Resveratrol, pterostilbene, thiab piceatannol hauv tshuaj tiv thaiv berries.
- HyperFoods: Tshuab ntse daim ntawv qhia txog mob qog noj ntshav hauv cov zaub mov.
- Fisetin: noj zaub mov antioxidant rau kev txhawb nqa kev noj qab haus huv.
Khoom noj khoom haus tus kheej rau Cancer!
Cancer hloov nrog lub sijhawm. Kho thiab hloov kho koj cov khoom noj khoom haus raws li kev qhia mob qog noj ntshav, kev kho mob, kev ua neej, kev nyiam zaub mov, kev ua xua thiab lwm yam.