highlights
Cov qog nqaij hlav me me zoo li leukemia uas tau kho nrog ntau dua koob tshuaj ntawm cov tshuaj kho mob xws li cyclophosphamides thiab anthracyclines, ntsib kev pheej hmoo ntawm kev mob qog noj ntshav tom qab / theem nrab. Secondary/Second Cancers nyob rau hauv me nyuam yaus muaj txoj sia nyob yog ib qho tshwm sim ntev cov tshuaj tua kab mob phiv.
Kev Menyuam Kab Menyuam Kiag
Mob qog noj ntshav thaum yau tshwm sim hauv cov menyuam yaus, cov hluas thiab cov hluas. Cov mob qog noj ntshav tshaj plaws hauv cov menyuam yaus yog leukemia, mob qog noj ntshav. Lwm hom mob qog noj ntshav xws li lymphoma, qog hlwb, sarcomas thiab lwm cov qog nqaij hlav tuaj yeem tshwm sim. Ua tsaug rau kev kho kom zoo dua qub, muaj ntau dua 80% ntawm cov neeg muaj mob qog noj ntshav thaum yau hauv Asmeskas. Kev kho mob nyob ntawm hom mob qog noj ntshav tab sis tuaj yeem suav nrog kev phais, cov kws khomob, radiation therapy thiab ntau tsis ntev los no txawm immunotherapy. Txawm li cas los xij, raws li National Pediatric Cancer Foundation, lawv kwv yees tias ntau dua 95% ntawm cov neeg muaj mob qog noj ntshav thaum yau yuav muaj teeb meem loj txog kev noj qab haus huv thaum lawv muaj 45 xyoos, uas tuaj yeem yog qhov tshwm sim ntawm lawv txoj kev kho mob qog noj ntshav ua ntej (https://nationalpcf.org/facts-about-childhood-cancer/).
Cov zaub mov noj tom qab kuaj mob qog noj ntshav!
Tsis muaj ob yam mob qog noj ntshav zoo ib yam. Mus dhau qhov txheej txheem kev noj zaub mov zoo rau txhua tus thiab txiav txim siab tus kheej txog zaub mov thiab tshuaj ntxiv nrog kev ntseeg siab.
Mob Cancer thib ob hauv Me Nyuam Mob Cancer Survivors
Nrog rau qhov muaj cov neeg muaj mob qog noj ntshav ntau, cov kws tshawb fawb los ntawm University of Minnesota Medical School tau tshuaj xyuas cov koom haum ntawm cov menyuam yaus mob qog noj ntshav uas tau txais kev kho mob nrog tshuaj kho mob nrog rau qhov tshwm sim ntawm cov mob qog noj ntshav tom qab (SMN) uas yog ib feem ntawm kev tshawb fawb txog kev mob qog noj ntshav thaum yau (Turcotte LM et al, J Clin Oncol., 2019). Lawv tau soj ntsuam SMNs hauv cov neeg muaj sia nyob uas tau kuaj pom thawj zaug muaj mob qog noj ntshav thaum lawv muaj hnub nyoog qis dua 21 xyoos, ntawm 1970-1999. Cov ntsiab lus tseem ceeb ntawm kev tshawb fawb pej xeem thiab kev tshawb pom ntawm lawv qhov kev tshuaj ntsuam yog:
- Lub hnub nyoog nruab nrab ntawm kev kuaj mob yog 7 xyoo thiab hnub nyoog nruab nrab ntawm kev soj ntsuam zaum kawg yog 31.8 xyoo.
- Lawv tau tshuaj xyuas ntau dua 20,000 tus menyuam yaus muaj sia nyob uas tau kho nrog kev kho mob ib leeg, kws khomob nrog rau kev kho hluav taws xob, kev kho hluav taws xob ib leeg lossis tsis yog.
- Cov menyuam yaus uas muaj txoj sia nyob tau kho nrog tshuaj kho mob ib leeg muaj 2.8 npaug ntawm kev pheej hmoo ntawm SMN.
- Tus nqi ntawm qhov tshwm sim ntawm SMN tau siab dua hauv cov menyuam yaus uas muaj sia nyob tau kho nrog kev kho platinum. Tsis tas li ntawd, rau cov tshuaj alkylating (xws li Cyclophosphamide) thiab anthracyclines (piv txwv li Doxorubicin), muaj cov tshuaj teb kev sib raug zoo pom ntawm cov koob tshuaj ntau dua ntawm cov tshuaj tua kab mob no thiab ntau dua qhov mob qog noj ntshav mis.
Kev pheej hmoo ntawm tus mob cancer mis thib ob hauv Leukemia lossis Sarcoma Survivors
Hauv lwm qhov kev tshuaj ntsuam ua ntej uas yog ib feem ntawm kev tshawb fawb txog kev mob qog noj ntshav thaum yau uas muaj 3,768 tus poj niam mob ntshav qab zib mellitus lossis mob qog noj ntshav sarcoma Cov neeg muaj txoj sia nyob uas tau kho nrog kev siv tshuaj kho mob ntau ntxiv xws li cyclophosphamide lossis anthracyclines, nws tau pom tias lawv muaj feem cuam tshuam nrog kev pheej hmoo ntawm kev mob qog noj ntshav theem nrab / thib ob. Muaj 5.3 npaug thiab 4.1 npaug ntxiv qhov kev pheej hmoo ntawm kev tsim mob qog noj ntshav thib ob hauv lub mis hauv sarcoma thiab leukemia raws. (Henderson TO et al., J Clin Oncol., 2016)
Kev pheej hmoo ntawm Secondary Skin Cancers nyob rau hauv Me Nyuam Mob Cancer Survivors uas ib zaug tau txais Radiotherapy
Raws li qhov kev tshawb pom los ntawm lwm txoj kev tshawb fawb hu ua DCOG-LATER cohort txoj kev tshawb fawb uas suav nrog 5843 Dutch cov neeg muaj mob qog noj ntshav thaum yau uas tau kuaj pom muaj ntau hom. Cancer Nyob nruab nrab ntawm xyoo 1963 thiab 2001, cov neeg muaj txoj sia nyob uas tau kho ib zaug nrog kev kho hluav taws xob muaj kev pheej hmoo ntawm cov qog nqaij hlav thib ob Cov kev tshawb fawb pom muaj kwv yees li 30 npaug ntawm kev pheej hmoo ntawm basal cell carcinomas hauv cov neeg muaj sia nyob no. Qhov no kuj yog nyob ntawm seb qhov chaw ntawm daim tawv nqaij raug thaum kho. (Jop C Teepen li al, J Natl Cancer Inst., 2019)
xaus
Hauv cov ntsiab lus, cov neeg mob qog noj ntshav thaum yau uas tau txais kev kho mob ntau dua ntawm cov tshuaj kho mob xws li cyclophosphamide lossis anthracyclines rau cov qog nqaij hlav xws li leukemia ntsib qhov kev pheej hmoo ntawm kev mob qog noj ntshav thib ob / theem nrab (ntev cov tshuaj khomob ntev). Yog li ntawd, kev pheej hmoo- txiaj ntsig tsom xam ntawm cancer Kev kho mob rau cov menyuam yaus thiab cov neeg laus yuav tsum pom zoo rau kev kho mob nrog kev txwv tsis pub siv tshuaj khomob ntau ntxiv thiab xav txog lwm txoj kev kho mob los yog ntau hom phiaj los txo cov kev pheej hmoo ntawm kev mob qog noj ntshav tom ntej.
Yam zaub mov twg koj noj thiab cov khoom noj uas koj noj yog qhov kev txiav txim siab koj ua. Koj qhov kev txiav txim siab yuav tsum suav nrog kev txiav txim siab ntawm kev hloov pauv noob caj noob ces, uas mob qog noj ntshav, kev kho mob txuas ntxiv thiab tshuaj ntxiv, txhua qhov ua xua, qhia txog kev ua neej nyob, hnyav, qhov siab thiab tus cwj pwm.
Kev npaj zaub mov noj rau mob qog noj ntshav los ntawm addon tsis yog los ntawm kev tshawb fawb hauv internet. Nws siv qhov kev txiav txim siab rau koj raws li kev tshawb fawb molecular siv los ntawm peb cov kws tshawb fawb thiab software engineers. Tsis hais seb koj puas mob siab rau nkag siab cov hauv paus txheej txheem biochemical molecular lossis tsis - rau kev npaj zaub mov noj rau mob qog noj ntshav uas xav tau kev nkag siab.
Pib tam sim no nrog koj cov phiaj xwm kev noj zaub mov zoo los ntawm kev teb cov lus nug ntawm lub npe mob qog noj ntshav, kev hloov pauv caj ces, kev kho mob txuas ntxiv thiab tshuaj ntxiv, txhua yam kev ua xua, tus cwj pwm, lub neej, pab pawg hnub nyoog thiab poj niam txiv neej.
Khoom noj khoom haus tus kheej rau Cancer!
Cancer hloov nrog lub sijhawm. Kho thiab hloov kho koj cov khoom noj khoom haus raws li kev qhia mob qog noj ntshav, kev kho mob, kev ua neej, kev nyiam zaub mov, kev ua xua thiab lwm yam.
Cov neeg mob cancer feem ntau yuav tsum tau ua nrog sib txawv kev kho mob tshuaj phiv uas cuam tshuam rau lawv lub neej zoo thiab saib rau lwm cov kev kho mob qog noj ntshav. Noj cov khoom noj khoom haus zoo thiab pabcuam ntxiv raws li kev txiav txim siab science (Tsis txhob twv thiab xaiv xaiv) yog cov tshuaj zoo tshaj plaws rau kev mob qog noj ntshav thiab kev kho mob ntsig txog phiv.