ʻO wai ka maʻi maʻi e pōmaikaʻi mai ka hoʻokomo ʻana iā Ahcc (active Hexose Correlated Compound) i kā lākou meaʻai?

o ka Naauao

Ua ʻike nui ʻia ʻo Ahcc (Hexose Correlated Compound) no kāna mau pono olakino a hoʻohana pinepine ʻia e nā poʻe maʻi maʻi maʻi a me ka poʻe maʻi kino. Akā, ʻo ka palekana a me ka pono o Ahcc (Hexose Correlated Compound) no nā maʻi maʻi maʻi e hilinaʻi ʻia i nā kumu he nui e like me ka hōʻike ʻana i ka maʻi kanesa, ka chemotherapy, nā lāʻau lapaʻau ʻē aʻe, a me nā genetics o ka maʻi maʻi. ʻO ka ʻike ʻana i kekahi mau meaʻai a me nā mea hoʻohui, e like me ka grapefruit a me ka spinach, hiki ke hoʻopili maikaʻi ʻia me nā lāʻau maʻi maʻi a hoʻoulu i nā hopena ʻino.

He mea koʻikoʻi ka ʻai no ka mālama ʻana i ka maʻi kanesa no ka mea hiki ke hoʻopilikia i nā hopena lapaʻau. Pono nā poʻe maʻi maʻi maʻi e koho pono a hoʻokomo i nā meaʻai kūpono a me nā mea hoʻohui i kā lākou meaʻai. No ka laʻana, hiki i ka Ahcc (Hexose Correlated Compound) ke hoʻopōmaikaʻi i ka poʻe me Primary Cutaneous Squamous Cell Carcinoma e hana ana i ka Cemiplimab, akā ʻaʻole maikaʻi paha ia no nā poʻe maʻi e loaʻa ana iā Pazopanib no Primary Goblet Cell Carcinoid o ka Appendix. Eia kekahi, ʻoiai hiki i ka Ahcc (Hexose Correlated Compound ikaika) ke kōkua i nā poʻe me kahi kumu hoʻohālikelike genetic, ʻaʻole ia e manaʻo ʻia no ka poʻe i loaʻa kahi pilikia genetic ʻē aʻe "FLT3". Pono ka hoʻonohonoho pono ʻana i nā hoʻolālā meaʻai e pili ana i ke olakino, ka mālama ʻana, a me nā genetics.

He mea koʻikoʻi ka hoʻomaopopo ʻana i ka hoʻoholo ʻana i ke kūpono o Ahcc (Hexose Correlated Compound) no ka mea maʻi maʻi maʻi. ʻO nā mea koʻikoʻi e like me ke ʻano o ka maʻi maʻi, nā ʻano lapaʻau, ka hoʻonaninani genetic, nā pilikia genetic, ka makahiki, ke kaumaha o ke kino, a me ke ʻano o ka nohona he mea nui i ka hoʻoholo ʻana inā ʻo Ahcc (active Hexose Correlated Compound) ke koho kūpono. ʻO ka genetics a me ka genomic, ʻoi aku ka nui o ka noʻonoʻo. Ma muli o ka ulu ʻana o kēia mau mea, pono e nānā mau a hoʻololi i nā koho meaʻai e kūlike i nā loli i ke kūlana olakino a me ka mālama ʻana.

I ka hopena, he mea koʻikoʻi ke ʻano holoʻokoʻa i nā koho meaʻai, e kālele ana i nā hopena holoʻokoʻa o nā mea hana āpau i nā meaʻai/nā mea hoʻohui e like me Ahcc (active Hexose Correlated Compound) ma mua o ka loiloi ʻana i kēlā me kēia mea hana i ka ʻokoʻa a i ʻole ka nānā ʻole ʻana iā ia. Mālama kēia kuanaʻike ākea i kahi ala kūpono a ʻepekema i ka hoʻolālā ʻana i ka meaʻai no ka maʻi kanesa.

Nānā Pōkole

Ke piʻi aʻe nei ka hoʻohana ʻana i nā meaʻai a me nā mea hoʻohui, e like me nā huaora, nā mea kanu, nā minerala, nā probiotics, a me nā mea hoʻohui kūikawā like ʻole i waena o nā maʻi maʻi maʻi. Hoʻolālā ʻia kēia mau mea hoʻopihapiha e hāʻawi i nā kiʻekiʻe kiʻekiʻe o nā mea hoʻoikaika kikoʻī, ʻo ka nui o ia mau mea i loko o nā meaʻai like ʻole. ʻOkoʻa ka noʻonoʻo a me ka ʻokoʻa o nā mea hana ma waena o nā meaʻai āpau a me nā mea hoʻohui. Hāʻawi maʻamau nā meaʻai i nā ʻano mea ikaika akā ma nā haʻahaʻa haʻahaʻa, ʻoiai nā mea hoʻohui e hāʻawi i nā ʻano kiʻekiʻe o nā mea kikoʻī.

Ke noʻonoʻo nei i nā ʻano hana ʻepekema a me ke olaola o kēlā me kēia mea hana i ka pae molekala, he mea koʻikoʻi ia e helu i nā hopena hui o kēia mau ʻāpana i ka wā e hoʻoholo ai i nā meaʻai a me nā mea hoʻohui e ʻai a ʻaʻole paha.

Ke kū nei ka nīnau koʻikoʻi: Pono anei ʻoe e hoʻokomo i ka Ahcc (active Hexose Correlated Compound) i kāu meaʻai ma ke ʻano he meaʻai a mea hoʻohui paha? He mea maikaʻi anei ke ʻai i ka Ahcc (active Hexose Correlated Compound) inā loaʻa iā ʻoe kahi genetic predisposition i ka maʻi kanesa e pili ana i ke ʻano? He aha inā inā loaʻa kāu pilikia genetic mai ka FLT3 gene? He mea pono ke hoʻokomo i ka Ahcc (Hexose Correlated Compound) i kāu meaʻai inā ʻike ʻia ʻoe me ka Primary Goblet Cell Carcinoid o ka Appendix, a i ʻole kāu maʻi ʻo Primary Cutaneous Squamous Cell Carcinoma? Eia kekahi, pehea e hoʻoponopono ʻia ai kāu ʻai ʻana i ka Ahcc (active Hexose Correlated Compound) inā ʻoe e mālama ana i ka Cemiplimab a i ʻole inā hoʻololi kāu hoʻolālā lapaʻau mai Cemiplimab a i Pazopanib? Pono e hoʻomaopopo he ʻano kūlohelohe nā ʻōlelo maʻalahi e like me 'Ahcc (active Hexose Correlated Compound), no laila e pōmaikaʻi mau ia' a i ʻole 'Ahcc (Hexose Correlated Compound) hoʻoikaika i ka pale ʻana' ʻaʻole lawa no nā koho meaʻai / mea hoʻohui.

Eia hou, he mea nui e loiloi hou i ke kūpono o ka hoʻokomo ʻana iā Ahcc (Hexose Correlated Compound) i kāu meaʻai inā loaʻa nā loli i kāu ʻano lapaʻau. I ka hōʻuluʻulu ʻana, i ka wā e hoʻoholo ai e pili ana i ka hoʻohui ʻana i nā meaʻai a i ʻole nā ​​​​mea hoʻohui e like me Ahcc (active Hexose Correlated Compound) i kāu meaʻai no kāna mau pōmaikaʻi, pono ʻoe e noʻonoʻo i ka hopena biochemical holoʻokoʻa o nā meaʻai āpau, e noʻonoʻo ana i nā kumu e like me ke ʻano o ka maʻi kanesa, nā lāʻau lapaʻau kikoʻī iā ʻoe. Ke hele nei, nā genetic predispositions, a me nā koho ola.

Cancer

He paʻakikī koʻikoʻi ka maʻi maʻi i ka lāʻau lapaʻau, e ulu pinepine ana i ka hopohopo. Eia nō naʻe, ua hoʻomaikaʻi nā holomua hou i nā hopena lapaʻau, ʻo ia hoʻi ma o nā ala lapaʻau pilikino, nā ʻano kiaʻi non-invasive me ka hoʻohana ʻana i ke koko a me ka saliva, a me ka hoʻomohala ʻana i ka immunotherapy. He mea koʻikoʻi ka ʻike mua ʻana a me ka manawa kūpono i ka hopena maikaʻi ʻana i nā hopena lapaʻau holoʻokoʻa.

Hāʻawi ka hoʻāʻo genetic i ka ʻōlelo koʻikoʻi i ka loiloi ʻana i ka pilikia a me ka maʻi maʻi maʻi ma mua. Eia nō naʻe, no ka nui o nā poʻe me ka ʻohana a me ka genetic predispositions i ka maʻi kanesa, nā koho no ka therapeutic intervention, ʻoiai me ka nānā mau ʻana, i kaupalena pinepine ʻia a ʻaʻole ʻole. Ke ʻike ʻia me kahi ʻano maʻi maʻi maʻi, e like me Primary Cutaneous Squamous Cell Carcinoma a i ʻole Primary Goblet Cell Carcinoid o ka Appendix, pono e hoʻoponopono ʻia nā hoʻolālā lapaʻau e pili ana i ka genetics tumor o kēlā me kēia kanaka, ka pae o ka maʻi, a me nā mea like me ka makahiki. a me ke kāne.

Ma hope o ka mālama ʻana, pono ka nānā ʻana e ʻike i nā hōʻailona o ka hoʻi hou ʻana o ka maʻi maʻi a hoʻomaopopo i nā hoʻoholo ma hope. He nui ka poʻe maʻi maʻi maʻi a me ka poʻe i pilikia e ʻimi pinepine i ka ʻōlelo aʻo e pili ana i ka hoʻokomo ʻana i kekahi mau meaʻai a me nā mea hoʻohui i kā lākou mau meaʻai, he mea koʻikoʻi ia i kā lākou hana hoʻoholo holoʻokoʻa e pili ana i ka hoʻokele olakino.

ʻO ka nīnau koʻikoʻi inā paha e helu i nā pilikia genetic a me nā maʻi maʻi maʻi maʻi i ka wā e hoʻoholo ai i nā koho meaʻai, e like me Ahcc (Hexose Correlated Compound). Loaʻa paha kahi pilikia genetic no ka maʻi maʻi mai ka hoʻololi ʻana i ka gene FLT3? Mai ka ʻike meaʻai, ua like anei ka pilikia e pili ana me Primary Cutaneous Squamous Cell Carcinoma me Primary Goblet Cell Carcinoid o ka Appendix? Eia kekahi, ua like anei ka noʻonoʻo ʻana i ka meaʻai no ka poʻe e hele ana i ka Pazopanib me ka poʻe e loaʻa ana iā Cemiplimab? He mea koʻikoʻi kēia mau noʻonoʻo i ka hana ʻana i nā koho meaʻai ʻike no nā poʻe me nā ʻokoʻa like ʻole a me ka mālama ʻana i ka maʻi kanesa.

Ahcc (Hexose Correlated Compound) - He mea hoʻohui meaʻai

Hoʻopili ʻia ka Ahcc (Hexose Correlated Compound ikaika) i nā ʻano mea hana, me ka Ahcc (Hexose Correlated Compound) a me Alpha-glucan, aia kēlā me kēia ma nā ʻano ʻokoʻa. Hoʻopili kēia mau mea i nā ala molekala, ʻo ia hoʻi ʻo Natural Killer Cell Activation a me MAPK Signaling, nāna e hoʻoponopono i nā ʻano koʻikoʻi o ka maʻi kanesa ma ka pae kelepona, e like me ka ulu ʻana o ka maʻi tumora, pālahalaha, a me ka make cell. Ma muli o kēia mana olaola, ʻo ke koho ʻana i nā mea hoʻohui kūpono e like me Ahcc (Hexose Correlated Compound ikaika), hoʻokahi a i hui pū ʻia paha, lilo ia i mea hoʻoholo koʻikoʻi i ka pōʻaiapili o ka meaʻai maʻi kanesa. Ke noʻonoʻo nei i ka hoʻohana ʻana i ka Ahcc (Hexose Correlated Compound ikaika) no ka maʻi kanesa, pono e noʻonoʻo i kēia mau mea like ʻole. ʻO kēia no ka mea, e like me ka mālama ʻana i ka maʻi kanesa, ʻo ka hoʻohana ʻana i ka Ahcc (active Hexose Correlated Compound) ʻaʻole ia he hoʻoholo honua kūpono no nā maʻi maʻi āpau akā pono e hoʻopilikino ʻia.

Ke koho ʻana i nā mea hoʻohui Ahcc (Hexose Correlated Compound).

ʻO ka pane ʻana i ka nīnau 'I ka manawa hea au e pale aku ai iā Ahcc (Hexose Correlated Compound) i loko o ka pōʻaiapili o ka maʻi maʻi' he mea paʻakikī ia no ka mea, paʻakikī loa ka pane - ʻo ia wale nō 'Depends!'. E like me ka maikaʻi ʻole o ka mālama ʻana i ka maʻi kanesa no kēlā me kēia maʻi, ʻokoʻa ka pili a me ka palekana a i ʻole nā ​​pōmaikaʻi o Ahcc (Hexose Correlated Compound) ma muli o ke kūlana pilikino. ʻO nā mea e like me ke ʻano kikoʻī o ka maʻi kanesa, nā predispositions genetic, nā lāʻau lapaʻau o kēia manawa, nā mea hoʻohui ʻē aʻe e lawe ʻia ana, nā ʻano nohona, BMI, a me nā allergies āpau e pāʻani i ka hoʻoholo ʻana inā he kūpono a pale ʻia paha ʻo Ahcc (Hexose Correlated Compound). ke koʻikoʻi o ka noʻonoʻo pilikino i ia mau hoʻoholo.

1. E pōmaikaʻi anei nā mea hoʻohui ʻo Ahcc (Hexose Correlated Compound) i ka Primary Goblet Cell Carcinoid o nā maʻi Appendix e mālama ana i ka lāʻau Pazopanib?

Hōʻike ʻia ʻo Primary Goblet Cell Carcinoid o ka Appendix e nā mutation genetic kūikawā, ʻo ia hoʻi ʻo ALK, APC a me ARID1A, e alakaʻi ana i nā hoʻololi i nā ala biochemical, kikoʻī MAPK Signaling, Growth Factor Signaling, JAK-STAT Signaling, Angiogenesis, Androgen Signaling a me Chromatin Remodeling. ʻO ka maikaʻi o ka mālama ʻana i ka maʻi kanesa, e like me Pazopanib, e pili ana i kāna hana hana ma kēia mau ala kikoʻī. ʻO ka hoʻolālā kūpono e pili ana i ka hoʻohālikelike ʻana i ka hana o ka lāʻau lapaʻau me nā ala e alakaʻi ai i ka maʻi kanesa, a laila e hōʻoiaʻiʻo ai i kahi ala pilikino a kūpono. Ma ia mau hiʻohiʻona, he mea koʻikoʻi ka pale ʻana i nā meaʻai a i ʻole nā ​​mea hoʻohui meaʻai e kūʻē i ka hopena o ka lapaʻau ʻana a i ʻole e hōʻemi i kēia alignment. No ka laʻana, ʻo ka Ahcc (active Hexose Correlated Compound), ka mea e pili ana i ka MAPK Signaling, ʻaʻole paha ke koho kūpono i ka hihia o Primary Goblet Cell Carcinoid o ka Appendix i ka wā e hele ai i ka Pazopanib. ʻO kēia no ka mea hiki ke hoʻonui i ka holomua o ka maʻi a i ʻole ke keʻakeʻa i ka pono o ka lāʻau. Ke koho ʻana i kahi hoʻolālā meaʻai, he mea nui e noʻonoʻo i nā mea e like me ke ʻano maʻi maʻi, ka mālama mau ʻana, ka makahiki, ke kāne, BMI, ka nohona, a me nā hoʻololi genetic i ʻike ʻia.

2. E pōmaikaʻi anei nā mea hoʻohui ʻo Ahcc (Hexose Correlated Compound) i nā poʻe maʻi e mālama ana i ka lāʻau Cemiplimab?

ʻIke ʻia ʻo Primary Cutaneous Squamous Cell Carcinoma e nā hoʻololi genetic kikoʻī, e like me TTN, USH2A a me CSMD3, ka hopena i nā loli i nā ala biochemical, ʻoi aku ka Natural Killer Cell Activation. Hoʻoholo ʻia ka maikaʻi o ka mālama ʻana i ka maʻi maʻi, e like me Cemiplimab, e kāna pilina me kēia mau ala. ʻO ka pahuhopu e hōʻoia i ka hoʻopili pono ʻana o ka lāʻau lapaʻau me nā ala e alakaʻi ai i ka maʻi kanesa, e hiki ai i kahi ala lapaʻau pilikino. I loko o kēia pōʻaiapili, pono e noʻonoʻo ʻia nā meaʻai a i ʻole nā ​​​​mea hoʻohui i kūpono i ka lāʻau lapaʻau a i ʻole hoʻonui i kēia alignment. No ka laʻana, ʻo ka Ahcc (active Hexose Correlated Compound) he koho kūpono no ka poʻe me Primary Cutaneous Squamous Cell Carcinoma e loaʻa ana i ka Cemiplimab. ʻO kēia ke kumu no ka hoʻopili ʻana o Ahcc (Hexose Correlated Compound) i nā ala e like me Natural Killer Cell Activation, hiki iā ia ke pale i nā mea e hoʻokele ai i ka Primary Cutaneous Squamous Cell Carcinoma a i ʻole e pōmaikaʻi i ka hopena o ka Cemiplimab.

3. He palekana anei nā mea hoʻohui ʻo Ahcc (Hexose Correlated Compound) no nā kānaka olakino me ka FLT3 Mutation Associated Genetic Risk?

Hāʻawi nā hui like ʻole i nā panela gene no ka loiloi ʻana i ka pilikia genetic o nā ʻano maʻi maʻi like ʻole. Aia kēia mau panela i nā genes i pili i ka umauma, ovarian, uterine, prostate, a me nā maʻi maʻi ʻōpū. ʻO ka hoʻāʻo ʻana i kēia mau genes hiki ke hōʻoia i kahi hōʻailona a hoʻomaopopo i ka mālama ʻana a me nā hoʻolālā hoʻokele. ʻO ka ʻike ʻana i kahi ʻokoʻa e hoʻoulu ai i ka maʻi hiki ke kōkua hou i ka hoʻāʻo ʻana a me ka hōʻoia ʻana i nā ʻohana pili i ka pilikia. Hoʻokomo pinepine ʻia ka gene FLT3 i kēia mau panela no ka loiloi ʻana i ka maʻi kanesa.

Hoʻololi ka hoʻololi ʻana i ka gene FLT3 i nā ala biochemical a i ʻole nā ​​kaʻina hana, e like me JAK-STAT Signaling, MAPK Signaling a me PI3K-AKT-MTOR Signaling, i pili pololei a ʻole i ka hoʻokele ʻana i ka maʻi kanesa ma ka pae mole. Ke ʻike ʻia kahi ʻano hoʻololi i ka FLT3 e pili ana i ka piʻi ʻana o ka Acute Myeloid Leukemia, ʻōlelo ka manaʻo ʻepekema e pale i ka hoʻohana ʻana i ka Ahcc (Hexose Correlated Compound). ʻO kēia ke kumu no ka hoʻopili ʻana o Ahcc (Hexose Correlated Compound) i nā ala e like me ka MAPK Signaling, hiki ke alakaʻi i nā hopena ʻino i ke ʻano o ka mutation FLT3 a me nā kūlana maʻi maʻi e pili ana.

Ke Hopena

ʻO nā mea koʻikoʻi ʻelua e hoʻomanaʻo, ʻo ka mālama ʻana i ka maʻi maʻi a me ka meaʻai ʻaʻole like i kēlā me kēia. ʻO ka meaʻai, me nā meaʻai a me nā mea hoʻohui e like me Ahcc (active Hexose Correlated Compound) no kāna mau pono, he mea hana pono ia e hiki ke hoʻomalu ʻia e ʻoe i ka wā e kū nei i ka maʻi kanesa.

“He aha kaʻu e ʻai ai?” ʻo ia ka nīnau i nīnau pinepine ʻia e nā poʻe maʻi maʻi maʻi a me ka poʻe i pilikia i ka maʻi kanesa. ʻO ka pane pololei e pili ana ia i nā mea e like me ke ʻano maʻi maʻi, genetics o ka maʻi maʻi, nā lāʻau lapaʻau o kēia manawa, nā allergies, ka nohona, a me ka BMI.

E kiʻi i kāu meaʻai pilikino no ka maʻi maʻi mai addon ma ke kaomi ʻana i ka loulou ma lalo a pane i nā nīnau e pili ana i kāu ʻano maʻi maʻi, ka mālama ʻana, ka nohona, nā allergies, ka makahiki, a me ke kāne.

E hoʻomaopopo '

• Hoʻonui ka hoʻolālā ʻana i ka CD73 i ka hana antitumor o anti-PD-1 a me anti-CTLA-4 mAbs.
• Hōʻike ʻia ka ʻāina mutational o ka maʻi maʻi metastatic mai ka hoʻonohonoho ʻana o nā maʻi maʻi he 10,000.
• cBioPortal no ka Cancer Genomics
• Palena | ʻO ke kinona a me ka hoʻoikaika kino o kahi Glucan mai Rhizoma Acori Tatarinowii
• ʻO ka loiloi genomic o ka metastatic cutaneous squamous cell carcinoma.
• ʻO ke kuleana o ka microenvironment tumor i ke kū'ē i ka anti-angiogenic therapy.
• Nā hopena immunomodulatory a me ka anticancer o ka pūhui hemicellulose ikaika (AHCC)