o ka Naauao
ʻAʻole ʻelua maʻi maʻi maʻi like ʻole, ʻaʻole hoʻi i mālama like ʻia, ʻaʻole pono e like ka meaʻai no kēlā me kēia. ʻO ka meaʻai ka meaʻai e like me ka pulupulu, nā mea kanu, nā huaʻai, nā nati, nā aila, nā mea kanu a me nā mea ʻala. Hoʻokomo pū ʻia ka meaʻai i nā mea hoʻohui he kiʻekiʻe kiʻekiʻe o nā meaʻai a i ʻole nā kiʻekiʻe kiʻekiʻe o kēlā me kēia mea i loaʻa i nā meaʻai. No nā maʻi maʻi e like me Multiple Myeloma i ka wā e hana ana i ka chemotherapy a i ʻole i ka wā e hoʻoholo ai ʻoe he pilikia genetic no ka hoʻomohala ʻana i ka Multiple Myeloma ma muli o ka hoʻololi ʻana o nā gene NRAS a me BRAF, he nīnau koʻikoʻi "He aha nā meaʻai e pono iaʻu ke pale aku a he aha nā meaʻai i kuhikuhi ʻia noʻu?" . ʻO ka nīnau pili ʻē aʻe "He aha nā meaʻai meaʻai e pono iaʻu ke pale aku?".
ʻAʻohe pane i kēia nīnau no maʻi pū e like me Multiple Myeloma hiki ke loaʻa ma o ka ʻimi pūnaewele. ʻO ka pane i ka nīnau ʻo "Ke hilinaʻi nei ia" no ka mea pono e hoʻonohonoho pono ʻia ka hoʻolālā meaʻai no ʻoe. Pono e hilinaʻi ka meaʻai i ka hōʻailona maʻi maʻi, ʻike genetic, makua a i ʻole pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, hoʻomau ʻia nā lāʻau lapaʻau inā loaʻa, lawe ʻia nā meaʻai meaʻai, nā makahiki a me nā mea e like me ke kāne, ke kaumaha, ke kiʻekiʻe, ke ola. , allergies a me nā meaʻai.
I ka pōkole - ʻo ke kaʻina hana e pane i nā nīnau e like me "Pono au e ʻalo i ka ʻai ʻana i ka hua Passion Fruit" a i ʻole "E hoʻokomo i ka Partridgeberry hua i kaʻu meaʻai" a i ʻole "Pono wau e hoʻemi i ka ʻai ʻana i ka mea kanu Yam" a i ʻole "Hiki iaʻu ke lawe i ka Ellagic Acid a me Dim supplements" ʻaʻole ia. maʻalahi e like me ka huli pūnaewele. Paʻakikī loa ke kaʻina hana a hoʻokumu ʻia nā pane ma ka ʻike o ka genetics, ka hana o ka mālama ʻana, nā mea hana i nā meaʻai a me kā lākou hana olaola pili. ʻO ka hope, pono e hoʻopilikino ʻia ka pane i ka nīnau meaʻai.
MANAʻO: E hoʻopilikino i kāu mau meaʻai a me nā mea hoʻohui i ka MYELOMA lehulehu, nā lapaʻau, nā ʻike Genetic, a me nā kūlana ʻē aʻe.
ʻO ka pahuhopu holoʻokoʻa o ka meaʻai pilikino no Multiple Myeloma ʻo ia ka hōʻemi ʻana i nā meaʻai a me nā mea hoʻohui meaʻai i loaʻa nā pilina maikaʻi ʻole me nā mea hoʻokele mole maʻi kanesa a me nā lāʻau hoʻomau. A e ʻike i kēlā mau meaʻai a me nā mea hoʻohui i loaʻa kahi hana pono. I kēlā me kēia manawa e hoʻololi ai i nā lāʻau lapaʻau a i ʻole ka maʻi maʻi - pono e hoʻomanaʻo i kāu mau meaʻai a me nā mea hoʻohui pono e loiloi hou. A ʻokoʻa paha nā pane i ka nīnau meaʻai ma muli o ka pōʻaiapili hou.
MANAʻO: HOʻOPIʻI I KO ʻOU ʻAʻAI NO KA MYELOMA MAU, I KA WA E HOOLOLI AI KA LAAU ANA, KA MA'I A ME NA KANAWAI EA.
No Multiple Myeloma
ʻO cBioPortal kekahi kumu o ka hōʻiliʻili o Ka maʻi 'aʻai ʻikepili maʻi mai nā hoʻokolohua lapaʻau ma waena o 350 me nā hōʻailona maʻi kanesa. Aia ka ʻikepili mai kēlā me kēia hoʻokolohua lapaʻau i ka inoa hoʻokolohua lapaʻau a me nā kikoʻī noiʻi e like me ka helu o nā maʻi, nā makahiki, ke kāne, ka lāhui, ka mālama ʻana, ka pūnaewele tumora, nā genetic aberrations i loaʻa a me ka nānā ʻana i nā ʻikepili āpau. Ua hoʻokumu mua ʻia ka cBioPortal no Cancer Genomics ma Memorial Sloan Kettering Cancer Center (MSK). Hoʻokipa ʻia ka pūnaewele cBioPortal lehulehu e ka Center for Molecular Oncology ma MSK - https://www.cbioportal.org/about.
Ma hope o nā mea koʻikoʻi e loaʻa mai ka ʻikepili lapaʻau no Multiple Myeloma mai cBioPortal. ʻO ka poʻe maʻi i kākau inoa ʻia i nā haʻawina no Multiple Myeloma aia i nā makahiki ma waena o 24 a 82 me ka makahiki awelika o 61. ʻO 66.2% o nā kāne a me 33.8% o nā wahine ka māhele ʻana o ke kāne ma kēia mau noiʻi lapaʻau. Mai ka nui o ka ma'i o 212; ʻO nā genes kiʻekiʻe me nā hoʻololi a me nā mea ʻino ʻē aʻe no Multiple Myeloma e komo pū nā genes KRAS, NRAS, TP53, BRAF a me MUC16. ʻO ka hāʻawi pinepine pinepine ʻana no kēia mau genes he 22.0%, 18.0%, 7.3%, 6.3% a me 6.3%. Hoʻopili ʻia kēia mau kikoʻī genetic tumor o Multiple Myeloma i ka molecular biochemical pathway drivers of cancer ma laila e hāʻawi ana i ka wehewehe ʻana i nā hiʻohiʻona hiʻohiʻona o Multiple Myeloma.
ʻO ka myeloma lehulehu he maʻi maʻi koko o nā pūnaʻi plasma i loaʻa i ka iwi iwi, ka ʻiʻo spongy i loko o ko mākou mau iwi, ka mea maʻamau e hana i nā ʻāpana like ʻole o ko mākou koko. He ʻāpana koʻikoʻi o ka ʻōnaehana pale o ke kino. Hoʻopuka lākou i nā antibodies e kōkua i ke kino e hakakā i ka maʻi. Hoʻomaka ka Myeloma i ka wā e loli ai nā pūnaewele plasma olakino a ulu ʻole i ka mana. Hiki paha kēia i nā ʻeha iwi he nui e hoʻonui ai i ka haʻihaʻi ʻana o ka iwi, no laila i kapa ʻia ʻo ka myeloma lehulehu. Hiki i nā pūnaewele plasma maʻamau ke puʻunaue wikiwiki i waho a hoʻopaʻa paha i ka ulu ʻana o nā mea ʻē aʻe i loko o ka iwi iwi, e like me nā ʻulaʻula ʻulaʻula, nā keʻokeʻo keʻokeʻo a me nā platelets. ʻAʻole wale kēia e hoʻohaʻahaʻa i ke kino o ke kino, akā hiki ke hoʻoulu i ka anemia mai ka nele o nā keʻena koko ʻulaʻula, ka nui o ke koko me nā ʻoki liʻiliʻi a me nā ʻeha ma muli o ka nele o nā platelets, a me ka emi ʻana o ka hiki ke hakakā i nā maʻi, mai ka nele o nā keʻokeʻo keʻokeʻo. . ʻAʻole hiki i nā cell Myeloma ke hana i nā antibodies e hana ana akā hana i kahi protein M i hiki ke kūkulu ʻia i loko o ke koko a me ka mimi, hiki ke hōʻino i nā puʻupaʻa a me nā ʻāpana ʻē aʻe, ma waho aʻe o ka hōʻemi ʻana i ka pale. ʻO ke kanaka olakino i ʻike ʻia he liʻiliʻi ka M protein i ʻōlelo ʻia he monoclonal gammopathy of undetermined significance (MGUS), ka mua o ka myeloma lehulehu.
Ua manaʻo ʻia nā hihia hou o ka myeloma lehulehu i 2022 ma luna o 30,000, ma kahi o 1.8% o nā hihia maʻi maʻi hou a pau. ʻO ka helu ola 5 makahiki no nā poʻe maʻi me ka myeloma lehulehu ma kahi o 58% (Ref: seer.cancer.gov). ʻO ka mālama ʻana i ka myeloma lehulehu e pili ana i ka mālama ʻana i ka maʻi a me ka mālama kākoʻo e hoʻomaikaʻi i ka maikaʻi o ke ola, e like me ka hoʻomaha ʻana i nā hōʻailona a me ka mālama ʻana i ka meaʻai maikaʻi me nā meaʻai kūpono a me nā mea hoʻohui kūlohelohe. Aia ka papahana lapaʻau i ka induction therapy no ka hoʻomalu wikiwiki ʻana i ke kanesa; ʻO ka lāʻau hoʻohui me ka ʻoi aku o ka chemotherapy a i ʻole ka hoʻololi ʻana o ka iwi iwi/stem cell a me ka mālama mālama ʻana i kahi manawa lōʻihi e pale ai i ka hoʻi hou ʻana o ka maʻi kanesa. ʻO nā lāʻau lapaʻau e pili ana i ka chemotherapy, ka lāʻau lapaʻau i hoʻopaʻa ʻia, nā lāʻau immunomodulatory, steroids, nā lāʻau hoʻololi iwi, a me ka immunotherapy. ʻO nā meaʻai kūpono a me nā mea hoʻohui kūlohelohe i kūlike me ka lāʻau lapaʻau hiki ke kōkua hou i ka hoʻomaikaʻi ʻana i ka maikaʻi o ka maʻi. (Ref: https://www.cancer.net/cancer-types/multiple-myeloma/introduction; https://www.cancer.org/cancer/multiple-myeloma/about/key-statistics.html)
ʻO ke koʻikoʻi o ka meaʻai no ka myeloma lehulehu
ʻO nā meaʻai a pau a me nā mea hoʻohui meaʻai he hōʻiliʻili o hoʻokahi a ʻoi aku ka nui o nā mea kemika ikaika ma nā ʻano like ʻole a me nā nui. Hiki i ka hana o kekahi mau mea hana i loko o ka meaʻai ke loaʻa nā pilina ʻino aʻo nā mea hana ʻē aʻe i loko o ka meaʻai hoʻokahi ke kākoʻo mai ka pōʻaiapili o Multiple Myeloma. No laila he mau hana maikaʻi a maikaʻi ʻole ka meaʻai like ʻole a pono ka nānā ʻana i ka hopena i hui ʻia e hana i kahi hoʻolālā meaʻai pilikino.
No ka laʻana, loaʻa i ka Passion Fruit nā mea ikaika Vitamin C, Oleic Acid, Linolenic Acid, Linoleic Acid, Vitamin A a me nā mea ʻē aʻe. A loaʻa iā Partridgeberry nā mea ikaika Resveratrol, Beta-sitosterol, Stigmasterol a me nā mea ʻē aʻe. Loaʻa paha i kekahi o kēia mau mea ikaika o ka meaʻai hoʻokahi nā hopena kū'ē a no laila e ʻōlelo ʻia e ʻike i nā meaʻai i ʻōlelo ʻia ma muli o ka nānā ʻana o nā mea nui kiʻekiʻe i loko o nā meaʻai.
No nā maʻi maʻi e like me Multiple Myeloma, hoʻāla a hoʻopaʻa ʻia paha i nā ala biochemical i koho ʻia e like me Growth Factor Signaling, Extracellular Matrix Remodelling, RAS-RAF Signaling, MAPK Signaling he mea nui i ka hoʻoulu ʻana i ka ulu maʻi kanesa. Hoʻohana like nā lāʻau lapaʻau like ʻole ma o nā hana molekala ʻē aʻe ʻaʻole pono e hoʻopau ʻia e kāu mau meaʻai a me nā mea hoʻohui. Loaʻa i nā meaʻai a me nā mea hoʻohui meaʻai i nā mea hana like ʻole i loaʻa i kēlā me kēia me kahi hana molekala ma nā ala biochemical like ʻole. No laila, ʻo ka ʻai ʻana i kekahi mau meaʻai a me nā mea hoʻohui meaʻai e ʻōlelo ʻia me kahi lapaʻau kūikawā o Multiple Myeloma, ʻoiai ʻaʻole ʻōlelo ʻia ka ʻai ʻana i kekahi mau meaʻai a me nā mea hoʻohui.
Hoʻokahi hewa maʻamau i ka loaʻa ʻana o nā meaʻai e ʻai ai a ʻaʻole ʻole - ʻo ia ka noʻonoʻo ʻana i kekahi mau mea ikaika i loko o nā meaʻai e pili ana i ka ʻimi pūnaewele a nānā ʻole i ke koena. No ka mea, he mau hopena kū'ē paha nā mea hana like ʻole i loko o nā meaʻai i nā ala biochemical kūpono - pono e noʻonoʻo i nā mea hoʻoikaika kiʻekiʻe a pau i loaʻa i ka nui a ʻoi aku ka nui ma mua o ka nui o nā mea i loko o ka meaʻai.
MANAʻO: E ʻimi i nā meaʻai i manaʻo ʻia a ʻaʻole i manaʻo ʻia no ka MYELOMA lehulehu - e noʻonoʻo i nā mea hana kiʻekiʻe i loko o nā meaʻai.
Nā meaʻai no Multiple Myeloma e mālama ana i ka chemotherapy
Ma Multiple Myeloma - nā genes KRAS, NRAS, TP53, BRAF a me MUC16 he nui nā hanana o ka genomic abnormalities. ʻAʻole pili kēia mau genes a pau Ka maʻi 'aʻai - ʻoiai ua hōʻike ʻia lākou. Hoʻopau pololei kekahi o kēia mau genes i ka hoʻopunipuni ʻana i nā ala biochemical biochemical e pili ana i ka maʻi kanesa. ʻO kekahi o nā ala e pili ana i ka Multiple Myeloma ʻo Growth Factor Signaling, Extracellular Matrix Remodelling, Angiogenesis a me nā mea ʻē aʻe. ʻO Bortezomib kekahi o nā chemotherapies i hoʻohana ʻia no ka mālama ʻana i ka maʻi kanesa. ʻO ka manaʻo o ka lapaʻau e hōʻole a hoʻopau paha i nā hopena o nā mea hoʻokele ala biochemical Growth Factor Signaling, Extracellular Matrix Remodelling, Angiogenesis i mea e hōʻemi ai i ka piʻi ʻana o ka maʻi a keʻakeʻa i ka ulu ʻana. ʻO kēlā mau meaʻai i hui pū ʻia me nā mea ikaika e kākoʻo i ka hana lapaʻau a ʻaʻole hoʻonui i nā mea hoʻokele maʻi, ʻo ia nā meaʻai a me nā mea hoʻohui e hoʻokomo ʻia i loko o ka meaʻai pilikino. A like nō hoʻi - ʻaʻole kākoʻo ʻia kēlā mau meaʻai i hui pū ʻia me nā mea hoʻoikaika kino i ka hana lapaʻau akā hoʻopau i ka hoʻolaha ʻana i nā maʻi maʻi, ʻaʻole ia e ʻōlelo ʻia i kāu hoʻolālā meaʻai pilikino.
OLELO HOOLAHA: E HAALELE i na mea ai a me na mea ai i kokua ole i ka ma'i ma'i.
ʻAi hou aku i nā pulu, ʻeleʻele Pea a i ʻole Pigeon Pea?
He ʻāpana koʻikoʻi nā pulu i nā meaʻai he nui. ʻO nā mea hana i loko o ka Pea ʻEleʻele he Vitamin C, Daidzein, Oleic Acid, Linolenic Acid, Beta-carotene a me nā mea ʻē aʻe. ʻOiai nā mea ikaika i loko o ka Pigeon Pea he Vitamin C, Oleic Acid, Linolenic Acid, Genistein, Linoleic Acid a me nā mea ʻē aʻe.
Hiki i ka Vitamin C ke hana i nā ala biochemical WNT Beta Catenin Signaling, Angiogenesis a me Hypoxia. Loaʻa iā Daidzein ka hana olaola ma nā ala biochemical PI3K-AKT-MTOR Signaling, Oxidative Stress a me Endoplasmic Reticulum Stress.
Hiki iā Genistein ke hoʻoponopono i nā ala biochemical o ka Oxidative Stress. He hana olaola ka Vitamin A ma nā ala biochemical Extracellular Matrix Remodelling. A laila.
I ka mālama ʻana i ka Myeloma Nui me ka chemotherapy Bortezomib - Manaʻo ʻia nā meaʻai e like me Black-eyed Pea e hoʻohālikelike ʻia me Pigeon Pea. ʻO kēia no ka mea ke hoʻopilikia nei nā mea hana Genistein a me ka Vitamin A i ka Pigeon Pea i ka hana lapaʻau ma ke kāpae ʻana i nā ala biochemical e hana ai ka chemotherapy. ʻOiai ke kākoʻo nei nā mea ikaika ʻo Vitamin C a me Daidzein i loko o ka Black-eyed Pea i ka hana lapaʻau ma o ka hoʻonui ʻana i ka hopena biochemical ala e hana ai ka chemotherapy.
OLELO HOOLAHA: KA PAI ELELE MA KA PAI PIGEON NO KA MYELOMA MAU MA KA LAPAIA ME CHEMOTHERAPY BORTEZOMIB NO KEKAHI MAU KUAI.
E ʻai hou aku i nā mea kanu, Giant Butterbur a i ʻole Yam?
He ʻāpana koʻikoʻi nā huaʻai i nā meaʻai he nui. ʻO nā mea hana i loko o Giant Butterbur he Vitamin C, Melatonin, Beta-sitosterol, Kaempferol, Vitamin A me nā mea ʻē aʻe. ʻOiai nā mea hana i loko o ka Yam he Vitamin C, Beta-sitosterol, Oleic Acid, Linolenic Acid, Dioscin a me nā mea ʻē aʻe.
Hiki i ka Vitamin C ke hana i nā ala biochemical WNT Beta Catenin Signaling, Angiogenesis a me Hypoxia. Loaʻa iā Melatonin ka hana olaola ma nā ala biochemical PI3K-AKT-MTOR Signaling, Growth Factor Signaling a me Oxidative Stress.
Hiki i ka Citric Acid ke hoʻopololei i nā ala biochemical o ka Oxidative Stress. He hana olaola ko Dioscin ma nā ala biochemical Notch Signaling. A laila.
I ka mālama ʻana i ka Myeloma Nui me ka chemotherapy Bortezomib - Manaʻo ʻia nā meaʻai e like me Giant Butterbur e hoʻohālikelike ʻia me Yam. ʻO kēia no ka mea ke hoʻopilikia nei nā mea hana ʻo Citric Acid a me Dioscin i ka Yam i ka hana lapaʻau ma ke kāpae ʻana i nā ala biochemical e hana ai ka chemotherapy. ʻOiai ke kākoʻo nei nā mea hana ʻo Vitamin C a me Melatonin i loko o Giant Butterbur i ka hana lapaʻau ma o ka hoʻonui ʻana i ka hopena biochemical ala e hana ai ka chemotherapy.
OLELO HOOLAHA: KAUOHA ANA O GIANT BUTTERBUR NO KEKAHI MYELOMA MA KA LAPAIA ME CHEMOTHERAPY BORTEZOMIB NO KEKAHI MAU KUAI.
ʻAʻole hiki ke hoʻopili iā MySQL: ʻAʻohe ala e hoʻokipa ai
E ʻai hou i nā huaʻai, Partridgeberry a i ʻole Passion Fruit?
ʻO nā huaʻai kekahi mea nui o nā meaʻai he nui. ʻO nā mea hana i loko o Partridgeberry ʻo Resveratrol, Beta-sitosterol, Stigmasterol a me nā mea ʻē aʻe. ʻOiai nā mea ikaika i loko o ka Passion Fruit he Vitamin C, Oleic Acid, Linolenic Acid, Linoleic Acid, Vitamin A a me nā mea ʻē aʻe.
Hiki iā Resveratrol ke hoʻoponopono i nā ala biochemical Hypoxia, Angiogenesis a me Endoplasmic Reticulum Stress. Loaʻa i ka Beta-sitosterol ka hana olaola ma nā ala biochemical WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling a me Oxidative Stress.
Hiki i ka Vitamin A ke hoʻoponopono i nā ala biochemical Extracellular Matrix Remodelling. Loaʻa i ka Citric Acid ka hana olaola ma nā ala biochemical Oxidative Stress. A laila.
I ka mālama ʻana i ka Myeloma Nui me ka chemotherapy Bortezomib - Hoʻohālikelike ʻia nā meaʻai e like me Partridgeberry i ka Passion Fruit. ʻO kēia no ka mea, ke hoʻopilikia nei nā mea hana ʻo Vitamin A a me Citric Acid i loko o ka Passion Fruit i ka hana lapaʻau ma ke kāpae ʻana i nā ala biochemical e hana ai ka chemotherapy. ʻOiai ke kākoʻo nei nā mea hana ʻo Resveratrol a me Beta-sitosterol i loko o Partridgeberry i ka hana lapaʻau ma o ka hoʻonui ʻana i ka hopena biochemical ala e hana ai ka chemotherapy.
KA MANAʻO: PARTRIDGEBERRY ALOHA NO KA HUA MAKEMAKE NO KA MYELOMA MAU MA KA LAAU ANA ME CHEMOTHERAPY BORTEZOMIB NO KEKAHI MAU KUAI.
E ʻai hou aku i nā nati, Chestnut a i ʻole Macadamia Nut?
He ʻāpana koʻikoʻi ka nati i nā meaʻai he nui. ʻO nā mea hana i loko o Chestnut ʻo Quercetin, Ellagic Acid, Vitamin C, Oleic Acid, Betulin a me nā mea ʻē aʻe. ʻOiai nā mea hana i loko o ka Macadamia Nut he Beta-sitosterol, Lauric Acid, Palmitic Acid, Myristic Acid, Folic Acid a me nā mea ʻē aʻe.
Hiki i ka Ellagic Acid ke hana i nā ala biochemical WNT Beta Catenin Signaling, Angiogenesis a me Extracellular Matrix Remodelling. He hana olaola ko Betulin ma nā ala biochemical Hypoxia, Oxidative Stress a me PI3K-AKT-MTOR Signaling.
Hiki i ka Lauric Acid ke hoʻohana i nā ala biochemical PI3K-AKT-MTOR Signaling. ʻO ka Palmitic Acid ka hana olaola ma nā ala biochemical WNT Beta Catenin Signaling, Angiogenesis a me Extracellular Matrix Remodelling. A laila.
I ka mālama ʻana i ka Myeloma Nui me ka chemotherapy Bortezomib - Hoʻohālikelike ʻia nā meaʻai e like me Chestnut i ka Macadamia Nut. ʻO kēia no ka mea, ʻo ka lauric Acid a me ka Palmitic Acid i Macadamia Nut e hoʻopilikia i ka hana lapaʻau ma ke kāpae ʻana i nā ala biochemical e hana ai ka chemotherapy. ʻOiai ke kākoʻo nei nā mea ikaika ʻo Ellagic Acid a me Betulin i loko o Chestnut i ka hana lapaʻau ma o ka hoʻonui ʻana i ka hopena biochemical ala e hana ai ka chemotherapy.
MANAʻO: KAUOHA ʻia ʻo Chestnut ma luna o ka nati MACADAMIA no ka MYELOMA lehulehu ma ka mālama ʻana me ka chemotherapie BORTEZOMIB no kekahi mau kūlana.
ʻO nā meaʻai no ka pilikia Genetic o Multiple Myeloma
ʻO kekahi o nā ala e loiloi i ka pilikia o Ka maʻi 'aʻai ʻo ia ma ka nānā ʻana no ka loaʻa ʻana o nā mea ʻino i loko o kahi pūʻulu o nā genes. Aia ka ʻike mua ma ka papa inoa o nā genes nona nā hoʻololi ʻana a me nā aberrations ʻē aʻe e hiki ke hoʻokō i ka pilikia i nā maʻi maʻi like ʻole. ʻO NRAS a me BRAF nā genes ʻelua nona nā mea ʻino i nā kumu pilikia no Multiple Myeloma. I loko o ia ʻano pilikia o ka maʻi kanesa - ʻoiai ʻaʻohe lāʻau lapaʻau i hiki i ke kauka ke kuhikuhi - hiki ke hoʻohana ʻia nā ala biochemical like ʻole i hiki ke hoʻokele molecular o Multiple Myeloma i alakaʻi no ka loaʻa ʻana o kahi hoʻolālā meaʻai pilikino i manaʻo ʻia. No Multiple Myeloma gene NRAS he hopena kumu ma nā ala olaola e like me G-protein-coupled Receptor Signaling, Growth Factor Signaling a me RAS-RAF Signaling. A he hopena koʻikoʻi ko BRAF ma nā ala olaola e like me RAS-RAF Signaling, MAPK Signaling a me Antigen Presentation. Pono e hoʻokomo ʻia nā meaʻai a me nā meaʻai meaʻai i loaʻa ka hana molekala e kāpae i nā ala biochemical nā hopena o nā genes e like me NRAS a me BRAF i loko o kahi hoʻolālā meaʻai pilikino. A ʻo kēlā mau meaʻai a me nā mea hoʻohui e hāpai i nā hopena o nā genes NRAS a me BRAF pono e pale ʻia.
E ʻai hou i nā pulu, Mung Bean a i ʻole Adzuki Bean?
ʻO nā mea hana i loko o ka Mung Bean ʻo Quercetin, Oleic Acid, Linolenic Acid, Vitamin C, Vitexin a me nā mea ʻē aʻe. ʻOiai nā mea hana i loko o ka Adzuki Bean ʻo Isoliquiritigenin, Glucaric Acid, Genistein, Folic Acid a me nā mea ʻē aʻe.
Hiki iā Quercetin ke hoʻopunipuni i nā ala biochemical MAPK Signaling, Cell Cycle Checkpoints a me RAS-RAF Signaling. Loaʻa i ka Vitamin C ka hana olaola ma nā ala biochemical P53 Signaling, MYC Signaling a me PI3K-AKT-MTOR Signaling.
Hiki i ka Folic Acid ke hoʻopunipuni i nā ala biochemical MAPK Signaling, Cell Cycle Checkpoints a me RAS-RAF Signaling. A laila.
No ka pilikia genetic o Multiple Myeloma ma muli o nā mea ʻino i loko o nā genes NRAS a me BRAF - Manaʻo ʻia nā meaʻai e like me Mung Bean e hoʻohālikelike ʻia me Adzuki Bean. ʻO kēia ke kumu o ka hoʻoikaika ʻana o ka Folic Acid i Adzuki Bean e hoʻoikaika hou i nā hopena o nā genes ma nā ala biochemical. ʻOiai ʻo Quercetin a me Vitamin C i loko o ka Mung Bean e hui pū me ka hopena o nā genes ma nā ala biochemical.
MANAʻO: KAUOHA ʻia ʻo MUNG BEAN MA KA AZUKI BEAN no ka hoʻemi ʻana i ka pilikia GENETIC o ka MYELOMA lehulehu ma muli o GENES NRAS a me BRAF.
E ʻai hou aku i nā mea kanu, Cassava a i ʻole Celery?
ʻO nā mea hana i loko o ka Cassava he Beta-sitosterol, Oleic Acid, Linolenic Acid, Vitamin C, Linoleic Acid a me nā mea'ē aʻe. ʻOiai nā mea hana i loko o ka Celery ʻo Apigenin, Quercetin, Oleic Acid, Linolenic Acid, Vitamin C a me nā mea ʻē aʻe.
Hiki i ka Vitamin C ke hoʻopololei i nā ala biochemical MAPK Signaling, Cell Cycle Checkpoints a me RAS-RAF Signaling. Loaʻa i ka Beta-sitosterol ka hana olaola ma nā ala biochemical P53 Signaling, MYC Signaling a me PI3K-AKT-MTOR Signaling.
Hiki iā Luteolin ke hoʻopunipuni i nā ala biochemical MYC Signaling. He hana olaola ko Chrysin ma nā ala biochemical MYC Signaling. A laila.
No ka pilikia genetic o Multiple Myeloma ma muli o nā abnormalities i loko o nā genes NRAS a me BRAF - Hoʻohālikelike ʻia nā meaʻai e like me ka Cassava i ka Celery. ʻO kēia no ka mea ʻo nā mea hoʻoikaika ikaika ʻo Luteolin a me Chrysin i ka Celery e hoʻoikaika hou i nā hopena o nā genes ma nā ala biochemical. ʻOiai ʻo nā mea hoʻoikaika ikaika ʻo Vitamin C a me Beta-sitosterol i loko o ka Cassava i hui pū ʻia he hopena hoʻopau i nā genes ma nā ala biochemical.
KA MANAʻO: KAUKAU ʻia ka CASSAVA ma luna o ka CELERY no ka hōʻemi ʻana i ka pilikia genetic o ka nui o ka myeloma ma muli o nā genes NRAS a me BRAF.
Nā Mea ʻai e ʻAi ai Ma hope o ka ʻike maʻi ʻaʻai!
ʻAʻohe ʻelua maʻi ʻaʻai. E hele i waho o nā kulekele meaʻai maʻamau no kēlā me kēia kanaka a hoʻoholo i nā koho pilikino e pili ana i ka meaʻai a me nā mea hoʻopihapiha me ka hilinaʻi.
ʻAi hou aku i nā huaʻai, ʻAlani a Strawberry paha?
ʻO nā mea hana i loko o ka ʻAlani ʻo D-limonene, Linalool, Modified Citrus Pectin, Oleic Acid, Linolenic Acid a me nā mea ʻē aʻe. ʻOiai nā mea ikaika i loko o Strawberry he Ellagic Acid, Lupeol, Cianidanol, Beta-sitosterol, Oleic Acid a me nā mea ʻē aʻe.
Hiki iā D-limonene ke hoʻopololei i nā ala biochemical MAPK Signaling, Cell Cycle Checkpoints a me RAS-RAF Signaling. Loaʻa i ka Vitamin C ka hana olaola ma nā ala biochemical P53 Signaling, MYC Signaling a me PI3K-AKT-MTOR Signaling.
Hiki iā Fisetin ke hoʻohana i nā ala biochemical MYC Signaling. Loaʻa i ka Pelargonidin ka hana olaola ma nā ala biochemical Cell Cycle Checkpoints, PI3K-AKT-MTOR Signaling a me MYC Signaling. A laila.
No ka pilikia genetic o Multiple Myeloma ma muli o nā abnormalities i loko o nā genes NRAS a me BRAF - Hoʻohālikelike ʻia nā meaʻai e like me ka ʻAlani me Strawberry. ʻO kēia no ka mea ʻo nā mea hana ʻo Fisetin a me Pelargonidin i loko o Strawberry e hoʻoikaika hou i nā hopena o nā genes ma nā ala biochemical. ʻOiai ʻo D-limonene a me ka Vitamin C i loko o ka ʻAlani hui pū me ka hopena o nā genes ma nā ala biochemical.
MANAʻO: KO ORANGE MA KA STRAWBERRY NO KA HOEMI I KA GENETIC RISK O MULTIPLE MYELOMA MA muli o Genes NRAS a me BRAF.
ʻAi hou aku i nā nati, Almond a i ʻole Cashew Nut?
ʻO nā mea hana i loko o ka Almond ʻo Quercetin, Vitamin E, Beta-sitosterol, Oleic Acid, Linolenic Acid a me nā mea ʻē aʻe. ʻOiai nā mea hana i loko o ka Cashew Nut he Palmitic Acid, Beta-sitosterol, Vitamin C, Gallic Acid, Butyric Acid a me nā mea ʻē aʻe.
Hiki i ka Beta-sitosterol ke hoʻopololei i nā ala biochemical Cell Cycle Checkpoints, P53 Signaling a me MYC Signaling. He hana olaola ko Quercetin ma nā ala biochemical MAPK Signaling, RAS-RAF Signaling a me PI3K-AKT-MTOR Signaling.
Hiki i ka Palmitic Acid ke hoʻopololei i nā ala biochemical MAPK Signaling. Loaʻa i ka Lauric Acid ka hana olaola ma nā ala biochemical MYC Signaling, PI3K-AKT-MTOR Signaling a me MAPK Signaling. A laila.
No ka pilikia genetic o Multiple Myeloma ma muli o nā mea ʻino i loko o nā genes NRAS a me BRAF - Hoʻohālikelike ʻia nā meaʻai e like me Almond me ka Cashew Nut. ʻO kēia no ka mea, ʻo nā mea hoʻoikaika ikaika ʻo Palmitic Acid a me Lauric Acid i loko o ka Cashew Nut e hoʻoikaika hou i nā hopena o nā genes ma nā ala biochemical. ʻOiai ʻo nā mea hana ʻo Beta-sitosterol a me Quercetin i loko o ka Almond me kahi hopena hoʻopau o nā genes ma nā ala biochemical.
MANAʻO: ALOHA ʻia ʻo ALMOND ma luna o ka cashew nut no ka hōʻemi ʻana i ka pilikia genetic o ka myeloma lehulehu ma muli o nā genes NRAS a me BRAF.
I ka Hōʻuluʻulu
ʻO kahi mea nui e hoʻomanaʻo ʻo ia Ka maʻi 'aʻai ʻAʻole like nā lāʻau lapaʻau no kēlā me kēia kanaka - a ʻaʻole pono kāu meaʻai. ʻO ka meaʻai e pili ana i ka meaʻai a me nā mea hoʻohui meaʻai he mea hana maikaʻi loa ia e mālama ʻia e ʻoe.
“He aha kaʻu e ʻai ai?” ʻo ia ka nīnau i nīnau pinepine ʻia ma ka pōʻaiapili o ka maʻi kanesa. He paʻakikī ka helu ʻana o ka pane a pili i ke ʻano maʻi kanesa, nā genomics i lalo, nā lāʻau lapaʻau o kēia manawa, nā allergies, ʻike ola, a me nā mea like me BMI.
Manaʻo ka hoʻolālā meaʻai pilikino addon i nā meaʻai a me nā mea hoʻohui e hōʻemi ana i nā pilina meaʻai maikaʻi ʻole a paipai i ke kākoʻo i nā lāʻau lapaʻau.
Hiki iā ʻoe ke hoʻomaka i kēia manawa a hoʻolālā i kahi hoʻolālā meaʻai pilikino no Multiple Myeloma ma ka pane ʻana i nā nīnau e pili ana i ke ʻano o ka maʻi kanesa, nā lāʻau lapaʻau o kēia manawa, nā mea hoʻohui, nā allergies, nā makahiki, ke kāne, a me ka ʻike ola.
He aha nā meaʻai āu e ʻai ai a me nā mea hoʻopihapiha āu e lawe ai i hoʻoholo. Pono e hoʻoholo i kāu hoʻoholo ʻana e pili ana i ka hoʻololi ʻana i nā ʻāpana o ka maʻi ʻaʻai, ka maʻi ʻaʻai, nā lāʻau e hoʻomau nei a me nā mea hoʻopihapiha, nā maʻi āpau, nā ʻike nohona, ke kaupaona, ke kiʻekiʻe a me nā ʻano.
ʻAʻole hoʻokumu ʻia ka hoʻolālā meaʻai no ka maʻi ʻaʻai mai addon ma ka ʻimi pūnaewele. Hoʻokele ia i ka hoʻoholo ʻana iā ʻoe ma muli o ka ʻepekema molekole i hoʻokō ʻia e ko mākou ʻepekema a me nā ʻenekini polokalamu. Nānā ʻole inā ʻoe e noʻonoʻo e hoʻomaopopo i ke ʻano o nā ʻolaola biōmika kumu a i ʻole ʻole - no ka hoʻolālā meaʻai no ka maʻi ʻaʻai e pono ai ka ʻike.
E hoʻomaka I K NOWIA manawa me kāu hoʻolālā meaʻai e ka pane ʻana i nā nīnau e pili ana i ka inoa o ka maʻi ʻaʻai, ka hoʻololi ʻana o nā kūpuna, nā mālama ʻana a me nā mea hoʻopihapiha mau, nā maʻi āpau, nā ʻano, ka nohona, nā makahiki a me nā kāne.
E hoʻomaopopo '
- Msk Impact 2017
- ʻO ka heterogeneity genetic ākea i ka myeloma lehulehu: nā hopena no ka lāʻau lapaʻau.
- ʻO ka Vitamin C ka mea i pepehi iā KRAS a me BRAF mutant colorectal cancer cells ma ka huli ʻana iā GAPDH.
- ʻO Daidzein ka hopena ma ka hormone refractory prostate cancer in vitro a in vivo i hoʻohālikelike ʻia me ka genistein a me ka soy extract: potentiation of radiotherapy.
- Hoʻoponopono maikaʻi ʻia ka hoʻopili ʻana i ka matrix extracellular e ka waika retinoic i nā cell HepG2.
- Hoʻokomo ʻo Resveratrol i ka autophagy ma ke kāohi pololei ʻana i ka mTOR ma o ka hoʻokūkū ATP.
- Hoʻokumu ka β-Sitosterol i ka Trx / Trx1 reductase e hoʻoulu i ka apoptosis ma nā pūnaewele A549 ma o ka ROS mediated mitochondrial dysregulation a me ka hoʻouluʻana o p53.
- Hoʻopau ʻo Melatonin i kāna-2, p38 MAPK, p-AKT, a me nā pae mTOR i loko o ka maʻi maʻi maʻi ovarian o nā ʻiole makemake i ka ethanol.
- Ka hopena o dioscin i ka hoʻolalelale ʻana i ka ate ma o ka hoʻāla ʻana i ke ala hōʻailona Notch1/Jagged1.
- Indeno [1,2-b] indole derivatives ma ke ʻano he papa hou o ka potent protein kinase CK2 inhibitors.
- Nā ʻano o ka maʻi puʻuwai hānau ma nā hānau hānau ʻo Dallas County. 1971-1984.
- Hoʻomaikaʻi ʻo Taurine i ka haʻahaʻa haʻahaʻa inorganic arsenic-induced insulin resistance ma ka hoʻoulu ʻana i ka hōʻailona PPARγ-mTORC2 a me ka pale ʻana i ka autophagy hepatic.
- Protein kinase a me HDAC inhibitors mai ka endophytic fungus Epicoccum nigrum.
- Hōʻike protooncogene sequential i ka hoʻoulu hou ʻana i ka ʻōpū ma hope o ka hōʻeha renal koʻikoʻi.
- Hoʻololi ʻo D-Limonene i ka mumū, ke koʻikoʻi oxidative a me ke ala Ras-ERK e kāohi ai i ka tumorigenesis ʻili murine.
- ʻO ke ʻano aniani o kahi paʻakikī kinase 6 e hilinaʻi ana i ka cyclin kanaka me ka mea hoʻopaneʻe flavonol, fisetin.
- Hoʻopau ʻo Pelargonidin i ka adipogenesis i loko o nā ʻāpana 3T3-L1 ma o ka pale ʻana i ke ala hōʻailona PPAR-γ.
- Nā lāʻau lapaʻau lapaʻau o nā antihistamines.
- Resveratrol, pterostilbene, a me piceatannol i loko o nā hua vaccinium.
- HyperFoods: Mīkini ka palapala ʻāina naʻauao o nā molekole e hahau ana i ka maʻi kanesa i nā meaʻai.
- Fisetin: he meaʻai antioxidant no ka hoʻolaha olakino.
Mea 'ai pilikino no ka ma'i 'a'ai!
Hoʻololi ka maʻi kanesa me ka manawa. Hoʻopilikino a hoʻololi i kāu meaʻai e pili ana i ka hōʻailona maʻi maʻi, ka mālama ʻana, ke ʻano o ka nohona, nā makemake meaʻai, nā allergies a me nā mea ʻē aʻe.