o ka Naauao
Hiki i nā hua ʻeleʻele a me ka ʻaila ʻeleʻele ke hōʻemi i nā hopena ʻaoʻao o ka mālama ʻana i ka chemotherapy no nā ʻano maʻi kanesa. Loaʻa i nā hua ʻeleʻele nā meaʻai meaʻai like ʻole e like me Thymoquinone. Ua hoʻāʻo ʻia nā pono anticancer o ka hua ʻeleʻele a me Thymoquinone i nā maʻi a me nā haʻawina lab. ʻO kekahi mau hiʻohiʻona o ka pōmaikaʻi o ka thymoquinone, e like me ka mea i hōʻike ʻia e kēia mau haʻawina, ʻo ia ka emi ʻana o ke kuni a me nā maʻi mai ka helu neutrophil haʻahaʻa i nā maʻi maʻi lolo pediatric, hoʻemi ʻia ka methotrexate (chemotherapy) pili i ka ʻaoʻao pili o ka maʻi leukemia a me ka pane maikaʻi ʻana i nā maʻi maʻi maʻi umauma i mālama ʻia me tamoxifen lāʻau lapaʻau. No ka mea he ʻawaʻawa ka ʻaila ʻeleʻele - lawe pinepine ʻia me ka meli. Ma muli o ka mea Ka maʻi 'aʻai a me ka mālama ʻana, ʻaʻole palekana paha kekahi mau meaʻai a me nā meaʻai. No laila, inā mālama ʻia ka mea maʻi maʻi maʻi umauma me ka tamoxifen a ʻai i ka aila hua ʻeleʻele - a laila he mea nui e pale aku i ka Parsley, Spinach a me Green Tea, a me nā mea hoʻohui meaʻai e like me Quercetin. No laila, he mea nui ia e hoʻopilikino i ka meaʻai i ka maʻi maʻi kūikawā a me ka mālama ʻana no ka loaʻa ʻana o nā pono mai ka meaʻai a me ka palekana.
ʻO ka poʻe wale nō i loaʻa i ka maʻi i manaʻo ʻole ʻia o ka maʻi kanesa a me kā lākou poʻe aloha e ʻike pono i ka wikiwiki o ka hoʻāʻo ʻana e noʻonoʻo i ke ala i mua, i ka ʻike ʻana i nā kauka maikaʻi loa, nā koho lapaʻau maikaʻi loa, a me nā ʻano nohona ʻē aʻe, nā meaʻai a me nā koho ʻē aʻe. hiki iā lākou ke loaʻa, no ka manawa hakakā e lilo i ka maʻi kanesa ʻole. Eia nō hoʻi, nui ka poʻe e hopohopo nei i nā lāʻau lapaʻau e pono ai lākou e hana ʻoiai nā hopena koʻikoʻi loa a ʻimi i nā ala e hoʻomaikaʻi ai i kā lākou chemotherapy me nā koho hoʻohui kūlohelohe e hōʻoluʻolu i nā hopena ʻaoʻao a hoʻomaikaʻi i ko lākou ola olakino. ʻO kekahi o nā mea hoʻohui kūlohelohe i loaʻa ka ʻikepili preclinical i loko Ka maʻi 'aʻai ʻO nā laina kelepona a me nā ʻano holoholona he ʻaila hua ʻeleʻele.
ʻO kaʻaila lūlū ʻeleʻele a me thymoquinone
Loaʻa ʻia ka aila hua ʻeleʻele mai nā ʻano ʻeleʻele, nā ʻanoʻano o kahi mea kanu i kapa ʻia ʻo Nigella sativa me ka poni ʻulaʻula, nā polū a i ʻole nā pua keʻokeʻo, ʻike ʻia he pua fennel. Hoʻohana pinepine ʻia nā ʻanoʻano ʻeleʻele i ka ʻaina ʻĀkia a me ke Kaiwaina. ʻO nā hua ʻeleʻele kekahi i ʻike ʻia me ke kumino ʻeleʻele, kalonji, kaʻa ʻeleʻele a me nā ʻano ʻaka ʻeleʻele.
Ua hoʻohana ʻia nā ʻanoʻano ʻeleʻele e hana i nā lāʻau no nā makahiki he mau kaukani. ʻO kekahi o nā meaola bioactive nui o ka aila hua ʻeleʻele me ka antioxidant, anti-inflammatory a me anti-cancer waiwai ʻo Tymoquinone.
Nā pono ke olakino laulā o ka ʻAno ʻEleʻele / Tymoquinone
Ma muli o kāna mau antioxidant a me nā anti-inflammatory waiwai, manaʻo ʻia ka aila hua ʻeleʻele / Thymoquinone he nui nā pono olakino. ʻO kekahi o nā kūlana e kūpono ai paha ka aila hua ʻeleʻele:
- Asthma: Hiki i ka hua ʻeleʻele ke hoʻēmi i ka puʻe, ka hū ʻana, a me ka hana o ka hanu i kekahi poʻe me ka hānō.
- Diabetes: Hiki i ka hua ʻeleʻele ke hoʻomaikaʻi i ke kiʻekiʻe o ke kō a me nā pae kolesterol i ka poʻe me ka maʻi kō.
- High ke koko; Lawe i ka hua ʻeleʻele e hōʻemi i ke kahe o ke koko e kahi liʻiliʻi.
- Infertility kāne: ʻO ka lawe ʻana i ka aila hua ʻeleʻele e hoʻonui ai i ka nui o ka sperm a pehea e neʻe wikiwiki ai i nā kāne me ka infertility.
- ʻEha umauma (mastalgia): Ke noi nei i kahi gel i loaʻa i ka aila hua ʻeleʻele i nā umauma i ka wā o ka menstrual cycle e hoʻemi ai i ka ʻeha i nā wahine me ka ʻeha o ka umauma.
Nā ʻaoʻao-hopena o ka aila hua ʻeleʻele / Thymoquinone
Ke hoʻopau ʻia i nā mea liʻiliʻi me he mea ʻala lā i ka papaʻai, e palekana paha nā ʻanoano ʻeleʻele a me nā aila hua ʻeleʻele no ka hapa nui o ka poʻe. Eia nō naʻe, palekana ʻole ka hoʻohana ʻana i ka aila hua ʻeleʻele a i ʻole nā mea hoʻopili i nā kūlana aʻe.
- Hāpai keiki: Hōʻalo i ka lawe kiʻekiʻe ʻana o ka aila hua ʻeleʻele a i ʻole nā mea unuhi i ka wā o ka hāpai ʻana no ka mea hiki ke hoʻolohi i ka uterus mai ka hana kuʻikahi.
- Nā maʻi hōʻeha: Hiki paha i ka ʻaila ʻeleʻele hua ke hoʻopili i ke kāpili ʻana o ke koko a hoʻonui i ka makaʻu o ke kahe ʻana. No laila, aia kahi hiki i ka ʻai ʻana o ka hua ʻeleʻele ke hana i nā maʻi kahe o ke koko.
- Hypoglycemia: Ma muli o ka hoʻohaʻahaʻa ʻana o ka aila hua ʻeleʻele i ke kiʻekiʻe o ke kō, e nānā pono nā mea maʻi diabetic e lawe nei i nā lāʻau no nā hōʻailona o ke kō kō.
- Ke koko haʻahaʻa: Hōʻalo i ka aila hua ʻeleʻele inā he haʻahaʻa kou kaomi ʻana ma muli o ka hoʻoliʻiliʻi ʻana o ka hua ʻeleʻele i ke kaomi koko.
Ma muli o kēia mau pilikia a me nā hopena ʻaoʻao, pono i kekahi e hōʻole i ka hoʻohana ʻana i ka aila hua ʻeleʻele inā hoʻonohonoho ʻia no kahi ʻoki.
Nā Mea ʻai e ʻAi ai Ma hope o ka ʻike maʻi ʻaʻai!
ʻAʻohe ʻelua maʻi ʻaʻai. E hele i waho o nā kulekele meaʻai maʻamau no kēlā me kēia kanaka a hoʻoholo i nā koho pilikino e pili ana i ka meaʻai a me nā mea hoʻopihapiha me ka hilinaʻi.
ʻO kaʻaila thymoquinone / ʻeleʻele hua no ka hoʻomaikaʻi ʻana i ka Chemotherapy Efficacy a i ʻole ka hōʻemi ʻana i nā hopena ʻaoʻao i nā Cancers
ʻO nā loiloi hou o nā puke pai ʻepekema i nānā ʻia i hōʻuluʻulu ʻia i kahi nui o nā hoʻokolohua hoʻokolohua e pili ana i nā hunaola a i ʻole nā hiʻohiʻona holoholona no nā ʻano maʻi ʻaʻai like ʻole i hōʻike i nā ʻano anticancer he nui o Thymoquinone mai ka aila hua ʻeleʻele, e like me ka mea e hoʻomaopopo ai i nā tumors i kekahi o nā chemotherapy maʻamau a me nā hana radiation (Mostafa AGM et al, Front Pharmacol, 2017; Khan MA et al, Oncotarget 2017).
Eia nō naʻe, he palena wale nō ka noiʻi a me nā noiʻi ʻana i nā kānaka i loiloi i nā hopena o ka thymoquinone a i ʻole ka aila hua ʻeleʻele ma nā ʻano like ʻole. maʻi pū ke mālama ʻia me nā chemotherapies kikoʻī a ʻole ʻole. Me nā maʻi maʻi he nui, hāʻawi ʻia ka chemotherapy a i ʻole radiation therapy ma hope o ka ʻoki ʻana no ka hoʻopau ʻana i nā keʻena maʻi maʻi i koe. Akā ʻaʻole kūleʻa kēia mau ʻōlelo kōkua a hiki ke hōʻemi i ka maikaʻi o ke ola o ka mea maʻi. Ma kēia blog, e nānā mākou i nā haʻawina lapaʻau like ʻole o ka aila hua ʻeleʻele a i ʻole thymoquinone i ka maʻi maʻi a ʻike inā pono ka ʻai ʻana i nā maʻi maʻi maʻi a hiki ke hoʻohana ʻia e hoʻonui i ka maʻiʻai o nā maʻi ʻaʻai.
ʻO nā hua ʻeleʻele / Thymoquinone me Chemotherapy hiki ke hoʻoliʻiliʻi i ka ʻaoʻao-hopena o ʻOiile Neutropenia i nā keiki me nā tumo o ka lolo.
He aha ʻo Fetile Neutropenia?
ʻO kekahi o nā ʻaoʻao ʻaoʻao o ka chemotherapy ka hoʻopau ʻana i ka momona o ka iwi a me nā hunaola pale. ʻO ka neile neferropenia ʻo Chrile kahi kumu ma muli o kahi neutrophil haʻahaʻa loa, kahi ʻano o nā keʻokeʻo koko keʻokeʻo i loko o ke kino, hiki i ka mea maʻi ke hoʻomohala i nā maʻi a me ke kuni. ʻO kēia kahi hopena hopena maʻamau i ʻike ʻia i nā keiki me nā tumors lolo e hana nei i ka chemotherapy.
Ke aʻo a me nā ʻike nui
I loko o kahi noiʻi olakino kaulike ʻole ʻia, i hana ʻia ma ke Kulanui ʻo Alexandria ma ʻAigupita, ua loiloi ka poʻe noiʻi i ka hopena o ka lawe ʻana i nā ʻano hua ʻeleʻele me ka chemotherapy, ma ka ʻaoʻao o ka neutropenia febrile i nā keiki me nā tumors lolo. 80 mau keiki ma waena o nā makahiki o 2-18 makahiki me nā tumors lolo, e hana ana i ka chemotherapy, i hāʻawi ʻia i nā hui ʻelua. Ua loaʻa i kekahi hui o 40 mau keiki he 5 g mau hua ʻeleʻele i kēlā me kēia lā ma loko o kā lākou hoʻomaʻamaʻa chemotherapy aʻo kahi hui o 40 keiki i loaʻa wale iā chemotherapy. (Mousa HFM et al, Keiki hopohopo a ke keiki., 2017).
Ua hōʻike ʻia nā hopena o kēia noi ʻana he 2.2% wale nō o nā keiki i ka hui e lawe ana i nā ʻanoʻano ʻeleʻele i loaʻa i nā neutropenia febrile ʻoiai i loko o ka pūʻulu hoʻomalu, 19.2% keiki i loaʻa nā hopena neutropenia febrile. ʻO kēia ke kumu o ka lawe ʻana o ka hua ʻeleʻele me ka chemotherapy e hoʻemi i ka hanana o nā neutropenia febrile e 88% ke hoʻohālikelike ʻia i ka pūʻulu kaohi.
ʻO ka aila hua ʻeleʻele / hiki i koumoquinone ke hōʻemi i ka Methotrexate Chemotherapy-i hoʻokomo ʻia i ka ʻaoʻao-hopena o ke ake / Hepato-ʻino i nā keiki me Leukemia
ʻO ka leukemia lymphoblastic huikau kekahi o nā maʻi ʻōpio ʻoi loa. ʻO Methotrexate kahi chemotherapy maʻamau i hoʻohana ʻia e hoʻonui i ke ola i nā keiki me ka leukemia. Eia nō naʻe, hiki i ka mālama ʻana i ka methotrexate ke hopena i nā hopena chemotherapy koʻikoʻi o ka hepatotoxicity a i ʻole ka ʻino o ke ake, no laila ke kaupalena nei i kona hopena.
Ke aʻo a me nā ʻike nui
A ua hoʻokolohua ʻia e ka poʻe noiʻi mai ke Kulanui ʻo Tanta ma ʻAigupita i ka hopena therapeutic hopena o ka aila hua ʻeleʻele ma ka hepatotoxicity i hoʻokomo ʻia i ka methotrexate i 40 mau keiki ʻAigupita i ʻike ʻia me ka leukemia lymphoblastic koʻikoʻi. Ua mālama ʻia ka hapalua o nā mea maʻi me ka methotrexate therapy a me ka aila hua ʻeleʻele a me ka hapalua hoʻomaha i mālama ʻia me ka methotrexate therapy a me placebo (ka mea i loaʻa ʻole ka waiwai therapeutic). Ua komo pū kēia hoʻopaʻa ʻana me 20 mau keiki olakino i kūlike ʻia no ka makahiki a me ka moekolohe a hoʻohana ʻia ma ke ʻano kaohi. (Adel A Hagag et al, Infect Disord Drug Target., 2015)
Ua ʻike ʻia ua hoʻopaʻa ʻia ka aila hua / ʻeleoquinone ʻeleʻele methotrexate chemotherapy i ka hopena o ka hepatotoxicity a hoʻonui i ka pākēneka o nā mea maʻi i loaʻa ke kala piha ʻana ma kahi o 30%, hoʻemi ʻia ka hoʻi hou ʻana ma kahi o 33%, a hoʻomaikaʻi i ke ola me ka maʻi ʻole ma kahi o 60%. hoʻohālikelike ʻia i ka placebo i nā keiki me ka leukemia lymphoblastic koʻikoʻi; akā naʻe, ʻaʻohe mea nui i hoʻomaikaʻi ʻia i ke ola holoʻokoʻa. Ua hoʻoholo nā kānaka noiʻi e koi ʻia ka aila hua ʻeleʻele / thymoquinone e like me kahi lāʻau adjuvant i nā keiki me Leukemia e mālama nei i ka methotrexate therapy.
ʻO ka lawe ʻana i kāu thymoquinone me Tamoxifen e hoʻomaikaʻi ai i kona hopena i nā maʻi maʻi maʻi hānai
ʻO ka maʻi kanesa o ka umauma kekahi o nā maʻi maʻamau maʻi pū i nā wahine a puni ka honua. ʻO Tamoxifen ka maʻamau o ka mālama hormonal therapy i hoʻohana ʻia i ka estrogen receptor positive (ER+ve) maʻi maʻi umauma. Eia naʻe, ʻo ka hoʻomohala ʻana i ke kūʻē tamoxifen kekahi o nā drawbacks nui. ʻO Thymoquinone, ka mea hana nui o ka aila hua ʻeleʻele, ua ʻike ʻia he cytotoxic i kekahi mau ʻano o nā laina kelepona maʻi maʻi kanaka multidrug.
Ke aʻo a me nā ʻike nui
I kahi noiʻi i hana ʻia e nā mea noiʻi mai ke Kulanui Central o Gujarat ma India, ke Kulanui ʻo Tanta ma ʻAigupita, ke Kulanui ʻo Taif ma Saudi Arabia a me ke Kulanui ʻo Benha ma ʻAigupita, ua loiloi lākou i ka hopena o ka hoʻohana ʻana i koumoquinone (ka mea nui o ka aila hua ʻeleʻele) me tamoxifen i nā mea maʻi me ka maʻi ʻaʻai umauma. Ua komo pū ka noiʻi me 80 mau maʻi wahine me ka maʻi ʻaʻai umauma i mālama ʻole ʻia, mālama ʻia me tamoxifen wale nō, mālama ʻia me thymoquinone (mai ka hua ʻeleʻele) hoʻokahi a mālama ʻia paha me koumoquinone a me tamoxifen. (Ahmed M Kabel et al, J Can Sci Res., 2016)
Ua ʻike ʻia ka noiʻi ʻana i ka lawe ʻana i koumoquinone me Tamoxifen i kahi hopena ʻoi aku ka maikaʻi ma mua o kēlā me kēia lāʻau i hoʻokahi wale nō i nā mea maʻi me ka maʻi ʻaʻai umauma. Ua hoʻoholo nā mea noiʻi ʻo ka hoʻohui ʻana o thymoquinone (mai ka aila hua ʻeleʻele) i tamoxifen e hōʻike i kahi ʻano therapeutic modality hou no ka mālama ʻana i ka maʻi ʻaʻai umauma.
Maluhia paha ʻo thymoquinone no nā mea maʻi me nā ʻōpala hōʻoki holomua, akā ʻaʻohe paha he hopena Therapeutic
Ke aʻo a me nā ʻike nui
I kahi mahele aʻu i hoʻopaʻa ai i hana ʻia ma 2009, e nā mea noiʻi mai ka Halemai ʻo King Fahd o ke Kulanui a me ke Kulanui ʻo King Faisal ma Saudi Arabia, ua loiloi lākou i ka palekana, nā mea ʻona a me nā hopena therapeutic o thymoquinone i nā mea maʻi me ka maʻi ʻaʻai kūpale no ka mea ʻaʻohe mālama maʻamau. a i ʻole nā ana palliative. I ke aʻo ʻana, ua hāʻawi ʻia i nā poʻe maʻi he 21 me nā tumors paʻa a i ʻole nā maʻi ʻino hematological i kūleʻa a hoʻi ʻole paha mai ka haukapila maʻamau i hāʻawi ʻia iā ʻoe me ka waha i koumoquinone ma kahi pae hoʻomaka o 3, 7, a 10mg / kg / lā. Ma hope o ka manawa maʻamau o 3.71 mau wiki, ʻaʻole i hōʻike ʻia nā hopena ʻaoʻao. Eia nō naʻe, ʻaʻole i ʻike ʻia kekahi hopena anti-cancer i kēia aʻo ʻana. Ma muli o ke aʻo ʻana ua hoʻoholo nā kānaka noiʻi ua ʻae maikaʻi ʻia ka thymoquinone ma kahi mahele lāʻau mai 75mg / lā a 2600mg / lā me ka loaʻa ʻole o nā lāʻau ʻona a me nā pane therapeutic. (Ali M. Al-Amri and Abdullah O. Bamosa, Shiraz E-Med J., 2009)
Panina
Nui nā haʻawina preclinical ma nā laina kelepona a me nā ʻano like ʻole Ka maʻi 'aʻai Ua ʻike mua nā ʻōnaehana hoʻohālike i nā waiwai anticancer lehulehu o Thymoquinone mai ka ʻaila hua ʻeleʻele. Ua hōʻike pū kekahi mau noiʻi lapaʻau ʻo ka lawe ʻana i ka aila hua ʻeleʻele / thymoquinone hiki ke hoʻemi i ka hopena o ka chemotherapy i hoʻokomo ʻia i ka hopena o ka febrile neutropenia i nā keiki me ka lolo lolo, Methotrexate i hoʻoulu ai i ka ate i nā keiki me ka leukemia a hiki ke hoʻomaikaʻi i ka pane ʻana i ka tamoxifen therapy i nā maʻi maʻi maʻi umauma. . Eia nō naʻe, pono e lawe ʻia nā mea hoʻohui aila hua ʻeleʻele a i ʻole thymoquinone ma ke ʻano he ʻāpana o ka meaʻai wale nō ma hope o ke kūkākūkā ʻana me kāu mea mālama ola e pale aku i nā pilina ʻino me nā hoʻomaʻamaʻa mau a me nā hopena ʻaoʻao ma muli o nā kūlana olakino ʻē aʻe.
He aha nā meaʻai āu e ʻai ai a me nā mea hoʻopihapiha āu e lawe ai i hoʻoholo. Pono e hoʻoholo i kāu hoʻoholo ʻana e pili ana i ka hoʻololi ʻana i nā ʻāpana o ka maʻi ʻaʻai, ka maʻi ʻaʻai, nā lāʻau e hoʻomau nei a me nā mea hoʻopihapiha, nā maʻi āpau, nā ʻike nohona, ke kaupaona, ke kiʻekiʻe a me nā ʻano.
ʻAʻole hoʻokumu ʻia ka hoʻolālā meaʻai no ka maʻi ʻaʻai mai addon ma ka ʻimi pūnaewele. Hoʻokele ia i ka hoʻoholo ʻana iā ʻoe ma muli o ka ʻepekema molekole i hoʻokō ʻia e ko mākou ʻepekema a me nā ʻenekini polokalamu. Nānā ʻole inā ʻoe e noʻonoʻo e hoʻomaopopo i ke ʻano o nā ʻolaola biōmika kumu a i ʻole ʻole - no ka hoʻolālā meaʻai no ka maʻi ʻaʻai e pono ai ka ʻike.
E hoʻomaka I K NOWIA manawa me kāu hoʻolālā meaʻai e ka pane ʻana i nā nīnau e pili ana i ka inoa o ka maʻi ʻaʻai, ka hoʻololi ʻana o nā kūpuna, nā mālama ʻana a me nā mea hoʻopihapiha mau, nā maʻi āpau, nā ʻano, ka nohona, nā makahiki a me nā kāne.
Mea 'ai pilikino no ka ma'i 'a'ai!
Hoʻololi ka maʻi kanesa me ka manawa. Hoʻopilikino a hoʻololi i kāu meaʻai e pili ana i ka hōʻailona maʻi maʻi, ka mālama ʻana, ke ʻano o ka nohona, nā makemake meaʻai, nā allergies a me nā mea ʻē aʻe.
ʻO nā mea maʻi maʻi maʻi e hana pinepine me nā mea ʻokoʻa nā hopena ʻaoʻao chemotherapy kahi e hoʻopili ai i ko lākou ola o ke ola a nānā i nā hoʻoponopono ʻokoʻa no ka maʻi ʻaʻai. Lawe ana i ka ka meaʻai kūpono a me nā mea hoʻopihapiha e pili ana i nā noʻonoʻo ʻepekema (ka hōʻalo ʻana i ka wānana a me ke koho wale ʻana) ʻo ia ka lāʻau kūlohelohe maikaʻi loa no ka maʻi ʻaʻai a me nā lāʻau e pili ana i nā hopena ʻaoʻao.