Wane ciwon daji ne zai amfana daga haɗa Asafoetida a cikin abincin su?

labarai

Asafoetida an san shi sosai don fa'idodin lafiyar sa kuma masu ciwon daji da waɗanda ke cikin haɗarin ƙwayoyin cuta galibi suna amfani da su. Duk da haka, aminci da tasiri na Asafoetida ga masu ciwon daji sun dogara da abubuwa da yawa kamar alamar cutar kansa, chemotherapy, sauran jiyya, da kwayoyin cutar ciwon daji. Sanin cewa wasu abinci da kari, irin su 'ya'yan innabi da alayyafo, na iya yin mu'amala mara kyau tare da magungunan ciwon daji kuma suna haifar da mummunan halayen yana da mahimmanci.

Abinci yana da mahimmanci don maganin ciwon daji saboda yana iya rinjayar sakamakon jiyya. Masu ciwon daji dole ne su zaɓi a hankali kuma su haɗa abinci da abubuwan da suka dace a cikin abincinsu. Misali, Asafoetida zai iya amfanar waɗanda ke da Carcinoma Primary Penile Squamous Cell Carcinoma da ke jurewa Mitomycin, amma bazai yi kyau ga marasa lafiya da ke karɓar Radiation don Primary Adamantinoma ba. Bugu da ƙari kuma, yayin da Asafoetida zai iya taimaka wa mutane masu haɗarin kwayoyin halitta "KMT2D", mai yiwuwa ba za a ba da shawarar ga waɗanda ke da haɗarin kwayoyin halitta "HRAS". Keɓance tsare-tsare na abinci bisa lafiya, jiyya, da kwayoyin halitta yana da mahimmanci.

Fahimtar cewa yin yanke shawara kan dacewar Asafoetida ga mai cutar kansa yana buƙatar keɓantacce yana da mahimmanci. Mahimman abubuwa kamar nau'in ciwon daji, hanyoyin jiyya, kayan shafa kwayoyin halitta, haɗarin kwayoyin halitta, shekaru, nauyin jiki, da salon rayuwa suna da mahimmanci wajen yanke shawara idan Asafoetida shine zaɓin da ya dace. Genetics da genomics, musamman, wani muhimmin la'akari ne. Tun da waɗannan abubuwan na iya haɓakawa, yana da mahimmanci a yi bita akai-akai da daidaita zaɓin abinci don dacewa da canje-canje a matsayin lafiya da magani.

A ƙarshe, cikakkiyar tsarin zaɓin abinci yana da mahimmanci, yana mai da hankali kan tasirin duk abubuwan da ke aiki a cikin abinci / kari kamar Asafoetida maimakon tantance kowane sashi mai aiki daban ko yin watsi da shi gaba ɗaya. Wannan faffadan hangen nesa yana haɓaka mafi ma'ana da tsarin kimiyya don tsara tsarin abinci don ciwon daji.

Takaitaccen Bayani

Amfani da kayan abinci da abubuwan gina jiki, irin su bitamin, ganyaye, ma'adanai, probiotics, da ƙari na musamman daban-daban, suna tashi a tsakanin masu cutar kansa. An tsara waɗannan abubuwan kari don sadar da babban taro na takamaiman kayan aiki masu aiki, waɗanda yawancin su ma suna cikin abinci daban-daban. Mahimmanci da bambancin kayan aiki masu aiki sun bambanta tsakanin abinci duka da kari. Abincin yawanci yana ba da kewayon kayan aiki masu aiki amma a ƙananan ƙima, yayin da kari ke ba da babban taro na takamaiman sinadarai.

Yin la'akari da bambance-bambancen ayyukan kimiyya da nazarin halittu na kowane sashi mai aiki a matakin ƙwayoyin cuta, yana da mahimmanci a ƙididdige tasirin haɗin gwiwar waɗannan abubuwan yayin yanke shawarar abinci da kari don ci ko a'a.

Tambaya mai mahimmanci ta taso: Shin yakamata ku haɗa Asafoetida a cikin abincin ku azaman kayan abinci ko kari? Shin yana da kyau a ci Asafoetida idan kuna da yanayin ƙwayar cuta zuwa kansa wanda ke da alaƙa da kwayar KMT2D? Me zai faru idan a maimakon haka haɗarin kwayoyin ku ya samo asali ne daga kwayar halittar HRAS? Shin yana da fa'ida a haɗa Asafoetida a cikin abincinku idan an gano ku da Primary Adamantinoma, ko kuma idan ganewar ku shine Primary Penile Squamous Cell Carcinoma? Haka kuma, ta yaya ya kamata a daidaita shan Asafoetida idan kuna shan maganin Mitomycin ko kuma idan shirin ku ya canza daga Mitomycin zuwa Radiation? Yana da mahimmanci a gane cewa sassauƙan ikirari kamar 'Asafoetida na halitta ne, don haka koyaushe yana da fa'ida' ko 'Asafoetida yana haɓaka rigakafi' ba su isa ga zaɓin abinci / ƙarin bayani ba.

Bugu da ƙari, yana da mahimmanci a sake tantance cancantar haɗawa da Asafoetida a cikin abincin ku idan akwai canje-canje a cikin tsarin kula da ku. A taƙaice, lokacin da za ku yanke shawara game da haɗa abinci ko kari kamar Asafoetida a cikin abincinku don fa'idodinsa, yakamata ku yi la'akari da tasirin sinadarai gabaɗaya na duk abubuwan sinadaran, la'akari da abubuwa kamar nau'in ciwon daji, takamaiman jiyya da kuke sha, tsinkayen kwayoyin halitta. , da zabin salon rayuwa.

Cancer

Ciwon daji ya kasance babban ƙalubale a fannin likitanci, galibi yana haifar da damuwa. Duk da haka, ci gaba na baya-bayan nan ya inganta sakamakon jiyya, musamman ta hanyar hanyoyin kulawa na musamman, hanyoyin sa ido mara kyau ta hanyar amfani da jini da samfurori na jini, da haɓakar rigakafi. Ganowa da wuri da shiga tsakani akan lokaci sun kasance masu mahimmanci a cikin tasiri mai tasiri ga sakamakon jiyya gabaɗaya.

Gwajin kwayoyin halitta yana ba da gagarumin alƙawari a kimanta haɗarin cutar kansa da lallacewa da wuri. Koyaya, ga mutane da yawa waɗanda ke da alaƙar dangi da ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙwayar cuta zuwa ciwon daji, zaɓuɓɓukan don shiga tsakani na warkewa, ko da tare da sa ido na yau da kullun, galibi suna iyakance ko babu. Da zarar an gano shi da wani nau'in ciwon daji, irin su Primary Penile Squamous Cell Carcinoma ko Primary Adamantinoma, ana buƙatar gyare-gyaren dabarun jiyya bisa la'akari da nau'in ciwon daji na mutum, matakin cutar, da kuma abubuwa kamar shekaru da jinsi."

Bayan jiyya, ci gaba da sa ido yana da mahimmanci don gano duk wani alamun sake dawowa da ciwon daji da kuma sanar da yanke shawara na gaba. Yawancin masu fama da cutar kansa da waɗanda ke cikin haɗari galibi suna neman shawara kan haɗa wasu abinci da kari a cikin abincinsu, wanda ke taka muhimmiyar rawa a cikin tsarin yanke shawara gabaɗaya game da kula da lafiya.

Tambaya mai mahimmanci ita ce ko za a haifar da haɗarin kwayoyin halitta da takamaiman cututtukan daji lokacin yanke shawarar zaɓin abinci, kamar Asafoetida. Shin haɗarin kwayoyin halitta don ciwon daji da ke fitowa daga maye gurbi a cikin KMT2D yana da tasirin hanyoyin sinadarai iri ɗaya kamar maye gurbi a cikin HRAS? Daga mahangar abinci mai gina jiki, shin haɗarin dake tattare da Primary Penile Squamous Cell Carcinoma yayi daidai da Primary Adamantinoma? Bugu da ƙari, shin la'akarin abincin ya kasance iri ɗaya ga waɗanda ke fuskantar Radiation kamar na waɗanda ke karɓar Mitomycin? Waɗannan la'akari suna da mahimmanci wajen yin ingantaccen zaɓin abinci ga mutanen da ke da haɗarin ƙwayoyin cuta daban-daban da magungunan kansa.

Asafoetida - Ƙarin Gina Jiki

Ƙarin Asafoetida ya ƙunshi kewayon sinadarai masu aiki, gami da Umbelliprenin da Linoleic Acid, kowannensu yana samuwa a wurare daban-daban. Wadannan sinadarai suna tasiri hanyoyin kwayoyin halitta, musamman Gyaran DNA, Epithelial zuwa Mesenchymal Transition, Growth Factor Signaling da PI3K-AKT-MTOR Signaling, wanda ke tsara muhimman al'amurran ciwon daji a matakin salula, irin su ci gaban tumo, yadawa, da mutuwar kwayar halitta. Ganin wannan tasirin ilimin halitta, zaɓin abubuwan da suka dace kamar Asafoetida, shi kaɗai ko a hade, ya zama yanke shawara mai mahimmanci a cikin mahallin abinci mai gina jiki na kansa. Lokacin yin la'akari da amfani da Asafoetida don ciwon daji, yana da mahimmanci a yi la'akari da waɗannan abubuwa da hanyoyi daban-daban. Wannan saboda, kama da magungunan ciwon daji, amfani da Asafoetida ba yanke shawara ba ne na duniya wanda ya dace da duk ciwon daji amma yana buƙatar keɓancewa.

Zabar Asafoetida Kari

Yin jawabi ga tambayar 'Yaushe zan guje wa Asafoetida a cikin mahallin Ciwon daji' yana da ƙalubale saboda amsar ta bambanta sosai - kawai 'Ya dogara!'. Kamar yadda duk wani maganin ciwon daji bazai yi tasiri ga kowane majiyyaci ba, dacewa da aminci ko fa'idodin Asafoetida ya bambanta dangane da yanayin mutum. Dalilai irin su takamaiman nau'in ciwon daji, ƙayyadaddun kwayoyin halitta, jiyya na yanzu, sauran abubuwan da ake amfani da su, yanayin salon rayuwa, BMI, da duk wani rashin lafiyan duk suna taka rawa wajen tantance ko Asafoetida ya dace ko yakamata a kauce masa, yana mai jaddada mahimmancin la'akari da keɓaɓɓen irin wannan yanke shawara.

1. Shin Kariyar Asafoetida za ta amfana da Majinyatan Adamantinoma na Farko waɗanda ke jurewa maganin Radiation?

Adamantinoma na farko yana da alamun maye gurbi na musamman, wato ARHGAP45, PI4KB da SDSL, waɗanda ke haifar da sauye-sauye a hanyoyin sinadarai, musamman Epithelial zuwa Mesenchymal Transition da Inositol Phosphate Signaling. Tasirin maganin ciwon daji, kamar Radiation, ya dogara ne akan tsarin aikinsa akan waɗannan takamaiman hanyoyin. Kyakkyawan dabarar ta ƙunshi daidaita aikin jiyya tare da hanyoyin da ke haifar da ciwon daji, ta yadda za a tabbatar da keɓaɓɓen hanya mai inganci. A cikin irin wannan yanayin, guje wa abinci ko abubuwan gina jiki waɗanda zasu iya magance tasirin jiyya ko rage wannan jeri yana da mahimmanci. Misali, kari na Asafoetida, wanda ke shafar Epithelial zuwa Mesenchymal Transition, maiyuwa ba zai zama zabin da ya dace ba a yanayin Primary Adamantinoma lokacin da ake fuskantar Radiation. Wannan saboda yana iya ko dai ya tsananta ci gaban cutar ko kuma ya tsoma baki cikin ingancin maganin. Lokacin zabar tsarin abinci mai gina jiki, yana da mahimmanci a yi la'akari da abubuwa kamar nau'in ciwon daji, jiyya masu gudana, shekaru, jinsi, BMI, salon rayuwa, da duk wani sanannen maye gurbi.

2. Shin Kariyar Asafoetida za ta amfana da Majinyatan Carcinoma na Farko na Squamous Cell Marasa lafiyar Mitomycin?

An gano Carcinoma na Farko na Squamous Cell Carcinoma ta takamaiman maye gurbi, irin su ABRAXAS1, PIK3CB da NUP93, wanda ke haifar da canje-canje a cikin hanyoyin biochemical, musamman Gyaran DNA, Hematopoiesis da Inositol Phosphate Signaling. Amfanin maganin ciwon daji, kamar Mitomycin, an ƙaddara ta hanyar hulɗar ta da waɗannan hanyoyin. Manufar ita ce a tabbatar da cewa maganin ya dace daidai da hanyoyin da ke haifar da ciwon daji, yana ba da damar tsarin kulawa na musamman. A cikin wannan mahallin, abinci ko kari waɗanda suka dace da jiyya ko haɓaka wannan jeri ya kamata a yi la'akari da su. Misali, ƙarin Asafoetida zaɓi ne na hankali ga waɗanda ke da Carcinoma na Farko na Penile Squamous Cell wanda ke jurewa Mitomycin. Wannan saboda Asafoetida yana rinjayar hanyoyi irin su Gyaran DNA, wanda zai iya ko dai ya hana abubuwan da ke motsa Carcinoma Primary Penile Squamous Cell Carcinoma ko amfana da tasirin Mitomycin.

3. Shin Kariyar Asafoetida Amintacciya ce ga Mutane Masu Lafiya tare da Matsalolin Halittar Halitta na HRAS?

Kamfanoni daban-daban suna ba da kwatancen kwayoyin halitta don tantance haɗarin kwayoyin cutar kansa daban-daban. Wadannan bangarori sun hada da kwayoyin halittar da ke da alaka da nono, ovarian, uterine, prostate, da ciwon daji na ciki. Gwajin waɗannan kwayoyin halitta na iya tabbatar da ganewar asali da kuma sanar da magani da dabarun gudanarwa. Gano bambance-bambancen da ke haifar da cututtuka na iya ƙara taimakawa a gwaji da gano dangin da ke cikin haɗari. Halin HRAS an haɗa shi da yawa a cikin waɗannan bangarorin don kimanta haɗarin kansa.

Maye gurbi a cikin kwayar halittar HRAS yana shafar hanyoyin ko matakai na sinadarai, kamar Siginar Factor Factor da RAS-RAF Signaling, waɗanda ke da hannu kai tsaye ko a kaikaice wajen tuƙi ciwon daji a matakin ƙwayoyin cuta. Lokacin da ƙungiyar kwayoyin halitta ta gano maye gurbi a cikin HRAS mai alaƙa da haɓakar haɗarin Pheochromocytoma Da Paraganglioma, dalilin kimiyya yana ba da shawarar guje wa amfani da ƙarin Asafoetida. Wannan saboda ƙarin Asafoetida yana tasiri hanyoyi kamar Siginar Factor Factor Growth, wanda zai iya haifar da mummunan tasiri a cikin mahallin maye gurbi na HRAS da yanayin ciwon daji masu alaƙa.

4. Shin Kariyar Asafoetida Amintacciya ce ga Mutane Masu Lafiya da KMT2D Mutation Associated Haɗin Halitta?

KMT2D yana taka muhimmiyar rawa a kimanta haɗarin kansa. Maye gurbi a cikin KMT2D na iya tarwatsa mahimman hanyoyin biochemical, gami da siginar siginar PI3K-AKT-MTOR da Oncogenic Histone Methylation, waɗanda ke shafar haɓakar ciwon daji. Idan rukunin kwayoyin halittar ku ya bayyana maye gurbi a cikin KMT2D da ke da alaƙa da Ciwon ciki Urothelial Carcinoma, la'akari da haɗa abubuwan da ake ci na Asafoetida a cikin shirin ku na abinci mai gina jiki. Waɗannan abubuwan kari na iya yin tasiri mai kyau ta hanyoyi kamar PI3K-AKT-MTOR Signaling, fa'ida ta samar da tallafi mai dacewa ga daidaikun mutane masu maye gurbin KMT2D da abubuwan da suka shafi lafiya.

a Kammalawa

Abu mafi mahimmanci guda biyu da ya kamata a tuna shine cewa maganin ciwon daji da abinci mai gina jiki ba iri ɗaya bane ga kowa. Abinci mai gina jiki, gami da abinci da kari kamar Asafoetida, kayan aiki ne mai inganci wanda zaku iya sarrafa shi yayin fuskantar cutar kansa.

"Me zan ci?" ita ce tambayar da aka fi yi wa masu fama da cutar kansa da kuma waɗanda ke cikin haɗarin kamuwa da cutar kansa. Amsar da ta dace ita ce ta dogara da dalilai irin su nau'in ciwon daji, kwayoyin halitta na ƙari, jiyya na yanzu, allergies, salon rayuwa, da BMI.

Samun keɓancewar abincin ku don ciwon daji daga addon ta danna hanyar haɗin da ke ƙasa da amsa tambayoyi game da nau'in ciwon daji, jiyya, salon rayuwa, rashin lafiyar ku, shekaru, da jinsi.

References

• cBioPortal don Cancer Genomics
• Kunna PPAR gamma da delta ta hanyar haɗin linoleic acid yana daidaita kariya daga cutar kumburin hanji na gwaji.
• cBioPortal don Cancer Genomics
• Pan-cancer bincike na dukan kwayoyin halitta.
• Maganin ciwon daji yana tsara yanayin dacewa na clonal hematopoiesis.
• Rediyon juriya a cikin ƙwayoyin kansar nono ana yin sulhu ta hanyar siginar TGF-β, nau'in nau'in epithelial-mesenchymal phenotype da ƙwayoyin cutar kansa.
• Matsayin phospholipase D a cikin ƙaura da mamayewa ta hanyar linoleic acid a cikin ƙwayoyin kansar nono.