Wane ciwon daji ne zai amfana daga haɗa Artemisinine a cikin abincin su?

labarai

Artemisinine an san shi sosai don fa'idodin lafiyar sa kuma masu ciwon daji da waɗanda ke cikin haɗarin ƙwayoyin cuta galibi suna amfani da su. Amma duk da haka, aminci da ingancin Artemisinine ga masu ciwon daji sun dogara da abubuwa da yawa kamar alamar cutar kansa, chemotherapy, sauran jiyya, da ƙwayoyin ƙwayoyin cuta. Sanin cewa wasu abinci da kari, irin su 'ya'yan innabi da alayyafo, na iya yin mu'amala mara kyau tare da magungunan ciwon daji kuma suna haifar da mummunan halayen yana da mahimmanci.

Abinci yana da mahimmanci don maganin ciwon daji saboda yana iya rinjayar sakamakon jiyya. Masu ciwon daji dole ne su zaɓi a hankali kuma su haɗa abinci da abubuwan da suka dace a cikin abincinsu. Misali, Artemisinine zai iya amfanar waɗanda ke da Primary Glioblastoma da ke jurewa Temozolomide, amma ba zai yi kyau ba ga marasa lafiya da ke karɓar Ifosfamide don Ciwon Ciwon Ciki na Farko na Squamous Cell. Bugu da ƙari kuma, yayin da Artemisinine zai iya taimaka wa mutane tare da haɗarin kwayoyin halitta "CDKN2A", ba za a iya ba da shawara ga waɗanda ke da haɗarin kwayoyin daban ba. Keɓance tsare-tsare na abinci bisa lafiya, jiyya, da kwayoyin halitta yana da mahimmanci.

Fahimtar cewa yanke shawara kan dacewa da Artemisinine ga mai ciwon daji yana buƙatar keɓantacce yana da mahimmanci. Mahimman abubuwa kamar nau'in ciwon daji, hanyoyin jiyya, kayan shafa kwayoyin halitta, haɗarin kwayoyin halitta, shekaru, nauyin jiki, da salon rayuwa suna da mahimmanci wajen yanke shawarar ko Artemisinine shine zaɓin da ya dace. Genetics da genomics, musamman, wani muhimmin la'akari ne. Tun da waɗannan abubuwan na iya haɓakawa, yana da mahimmanci a yi bita akai-akai da daidaita zaɓin abinci don dacewa da canje-canje a matsayin lafiya da magani.

A ƙarshe, cikakkiyar tsarin zaɓin abinci yana da mahimmanci, yana mai da hankali kan tasirin duk abubuwan da ke aiki a cikin abinci / kari kamar Artemisinine maimakon tantance kowane sashi mai aiki daban ko yin watsi da shi gaba ɗaya. Wannan faffadan hangen nesa yana haɓaka mafi ma'ana da tsarin kimiyya don tsara tsarin abinci don ciwon daji.

Takaitaccen Bayani

Amfani da kayan abinci da abubuwan gina jiki, irin su bitamin, ganyaye, ma'adanai, probiotics, da ƙari na musamman daban-daban, suna tashi a tsakanin masu cutar kansa. An tsara waɗannan abubuwan kari don sadar da babban taro na takamaiman kayan aiki masu aiki, waɗanda yawancin su ma suna cikin abinci daban-daban. Mahimmanci da bambancin kayan aiki masu aiki sun bambanta tsakanin abinci duka da kari. Abincin yawanci yana ba da kewayon kayan aiki masu aiki amma a ƙananan ƙima, yayin da kari ke ba da babban taro na takamaiman sinadarai.

Yin la'akari da bambance-bambancen ayyukan kimiyya da nazarin halittu na kowane sashi mai aiki a matakin ƙwayoyin cuta, yana da mahimmanci a ƙididdige tasirin haɗin gwiwar waɗannan abubuwan yayin yanke shawarar abinci da kari don ci ko a'a.

Tambaya mai mahimmanci ta taso: Shin yakamata ku haɗa Artemisinine a cikin abincin ku azaman kayan abinci ko kari? Shin yana da kyau a cinye Artemisinine idan kuna da yanayin ƙwayar cuta zuwa ciwon daji da ke hade da kwayar CDKN2A? Me zai faru idan a maimakon haka haɗarin kwayoyin ku ya samo asali ne daga kwayar halitta? Shin yana da fa'ida don haɗa Artemisinine a cikin abincinku idan an gano ku da ciwon daji na farko na mafitsara Squamous Cell, ko kuma idan ganewar asali shine Glioblastoma na farko? Bugu da ƙari, ta yaya ya kamata a daidaita shan Artemisinine idan kuna shan maganin Temozolomide ko kuma idan shirin ku ya canza daga Temozolomide zuwa Ifosfamide? Yana da mahimmanci a gane cewa maganganun masu sauƙi kamar 'Artemisinine na halitta ne, don haka yana da fa'ida koyaushe' ko 'Artemisinine yana haɓaka rigakafi' ba su isa ga zaɓin abinci / ƙarin bayani ba.

Bugu da ƙari, yana da mahimmanci don sake kimanta dacewa da haɗawa da Artemisinine a cikin abincin ku idan akwai canje-canje a cikin tsarin kula da ku. A taƙaice, lokacin da za ku yanke shawara game da haɗa abinci ko kari kamar Artemisinine a cikin abincinku don fa'idodinsa, yakamata ku yi la'akari da tasirin sinadarai gabaɗaya na dukkan sinadaran, la'akari da abubuwa kamar nau'in ciwon daji, takamaiman jiyya da kuke sha, tsinkayen kwayoyin halitta. , da zabin salon rayuwa.

Cancer

Ciwon daji ya kasance babban ƙalubale a fannin likitanci, galibi yana haifar da damuwa. Duk da haka, ci gaba na baya-bayan nan ya inganta sakamakon jiyya, musamman ta hanyar hanyoyin kulawa na musamman, hanyoyin sa ido mara kyau ta hanyar amfani da jini da samfurori na jini, da haɓakar rigakafi. Ganowa da wuri da shiga tsakani akan lokaci sun kasance masu mahimmanci a cikin tasiri mai tasiri ga sakamakon jiyya gabaɗaya.

Gwajin kwayoyin halitta yana ba da gagarumin alƙawari a kimanta haɗarin cutar kansa da lallacewa da wuri. Koyaya, ga mutane da yawa waɗanda ke da alaƙar dangi da ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙwayar cuta zuwa ciwon daji, zaɓuɓɓukan don shiga tsakani na warkewa, ko da tare da sa ido na yau da kullun, galibi suna iyakance ko babu. Da zarar an gano shi da wani takamaiman nau'in ciwon daji, irin su Primary Glioblastoma ko Primary Bladder Squamous Cell Carcinoma, dabarun jiyya na buƙatar a keɓance su bisa la'akari da nau'in ƙwayar cuta na mutum, matakin cutar, da abubuwa kamar shekaru da jinsi."

Bayan jiyya, ci gaba da sa ido yana da mahimmanci don gano duk wani alamun sake dawowa da ciwon daji da kuma sanar da yanke shawara na gaba. Yawancin masu fama da cutar kansa da waɗanda ke cikin haɗari galibi suna neman shawara kan haɗa wasu abinci da kari a cikin abincinsu, wanda ke taka muhimmiyar rawa a cikin tsarin yanke shawara gabaɗaya game da kula da lafiya.

Tambaya mai mahimmanci ita ce ko za a haifar da haɗarin kwayoyin halitta da takamaiman cututtukan daji lokacin yanke shawarar zaɓin abinci, kamar Artemisinine. Shin haɗarin kwayoyin halitta don ciwon daji da ke fitowa daga maye gurbi a cikin CDKN2A yana da tasirin hanyoyin sinadarai iri ɗaya? Daga mahangar abinci mai gina jiki, shin haɗarin da ke da alaƙa da Primary Glioblastoma ya yi daidai da Carcinoma na Mafitsara na Farko? Bugu da ƙari, shin la'akarin abincin ya kasance iri ɗaya ga waɗanda ke fuskantar Ifosfamide kamar waɗanda ke karɓar Temozolomide? Waɗannan la'akari suna da mahimmanci wajen yin ingantaccen zaɓin abinci ga mutanen da ke da haɗarin ƙwayoyin cuta daban-daban da magungunan kansa.

Artemisinine - Ƙarin Gina Jiki

Ƙarin Artemisinine ya ƙunshi kewayon sinadarai masu aiki, gami da Artemisinine, kowannensu yana samuwa a wurare daban-daban. Wadannan sinadaran suna tasiri hanyoyin kwayoyin halitta, musamman Rayuwar Kwayoyin Halitta, Tsarin Halitta, Gyaran DNA da Siginar Kwayoyin Halitta, wanda ke tsara mahimman abubuwan ciwon daji a matakin salula, kamar haɓakar ƙwayar cuta, yadawa, da mutuwar kwayar halitta. Ganin wannan tasirin ilimin halitta, zaɓin abubuwan da suka dace kamar Artemisinine, kadai ko a hade, ya zama yanke shawara mai mahimmanci a cikin mahallin abinci mai gina jiki na kansa. Lokacin yin la'akari da amfani da Artemisinine don ciwon daji, yana da mahimmanci a yi la'akari da waɗannan abubuwa da hanyoyi daban-daban. Wannan shi ne saboda, kama da maganin ciwon daji, amfani da Artemisinine ba yanke shawara ba ne na duniya wanda ya dace da dukan ciwon daji amma yana buƙatar zama na musamman.

Zabar Artemisinine Kari

Magance tambayar 'Yaushe zan guje wa Artemisinine a cikin mahallin Ciwon daji' yana da ƙalubale saboda amsar ta bambanta sosai - kawai 'Ya dogara!'. Kamar yadda duk wani maganin ciwon daji bazai yi tasiri ga kowane majiyyaci ba, dacewa da aminci ko amfanin Artemisinine ya bambanta dangane da yanayin mutum. Dalilai irin su takamaiman nau'in ciwon daji, ƙayyadaddun kwayoyin halitta, jiyya na yanzu, sauran abubuwan da ake amfani da su, yanayin salon rayuwa, BMI, da duk wani rashin lafiyan duk suna taka rawa wajen tantance ko Artemisinine ya dace ko yakamata a kauce masa, yana mai jaddada mahimmancin yin la'akari da keɓaɓɓen. irin wannan yanke shawara.

1. Shin Kariyar Artemisinine za ta amfana da Mafitsara na Farko Squamous Cell Carcinoma Marasa lafiyar Ifosfamide?

Ciwon ƙwayar ƙwayar cuta ta farko ta Squamous Cell Carcinoma tana da takamaiman maye gurbi, wato TTN, TP53 da KDM6A, waɗanda ke haifar da sauye-sauye a hanyoyin sinadarai, musamman Sel Cycle, Cell Cycle Checkpoints, Apoptosis and Suppressive Hisstone Methylation. Tasirin maganin ciwon daji, kamar Ifosfamide, ya dogara ne akan tsarin aikinsa akan waɗannan takamaiman hanyoyin. Kyakkyawan dabarar ta ƙunshi daidaita aikin jiyya tare da hanyoyin da ke haifar da ciwon daji, ta yadda za a tabbatar da keɓaɓɓen hanya mai inganci. A cikin irin wannan yanayin, guje wa abinci ko abubuwan gina jiki waɗanda zasu iya magance tasirin jiyya ko rage wannan jeri yana da mahimmanci. Misali, kari na Artemisinine, wanda ke shafar Tsarin Tantanin halitta, maiyuwa ba zai zama zabin da ya dace ba game da cutar sankarau ta farko ta mafitsara squamous lokacin da ake fuskantar Ifosfamide. Wannan saboda yana iya ko dai ya tsananta ci gaban cutar ko kuma ya tsoma baki cikin ingancin maganin. Lokacin zabar tsarin abinci mai gina jiki, yana da mahimmanci a yi la'akari da abubuwa kamar nau'in ciwon daji, jiyya masu gudana, shekaru, jinsi, BMI, salon rayuwa, da duk wani sanannen maye gurbi.

2. Shin Kariyar Artemisinine za su amfana na Farko na Glioblastoma Marasa lafiya da ke Jumu'a na Temozolomide?

Glioblastoma na farko ana gano shi ta takamaiman maye gurbi, kamar TRBV7-7, TAS2R46 da TP53, wanda ke haifar da canje-canje a cikin hanyoyin sinadarai, musamman Rayuwar Kwayoyin Halitta, Matsalolin Zagayewar Halitta da Apoptosis. Ingancin maganin ciwon daji, kamar Temozolomide, an ƙaddara ta hanyar hulɗar sa tare da waɗannan hanyoyin. Manufar ita ce a tabbatar da cewa maganin ya dace daidai da hanyoyin da ke haifar da ciwon daji, yana ba da damar tsarin kulawa na musamman. A cikin wannan mahallin, abinci ko kari waɗanda suka dace da jiyya ko haɓaka wannan jeri ya kamata a yi la'akari da su. Misali, kari na Artemisinine zabi ne na hankali ga wadanda ke da Glioblastoma na Farko da ke jurewa Temozolomide. Wannan saboda Artemisinine yana rinjayar hanyoyi kamar Rayuwar Kwayoyin Halitta, wanda zai iya ko dai ya hana abubuwan da ke motsa Glioblastoma na farko ko kuma amfana da tasirin Temozolomide.

3. Shin Kariyar Artemisinine Amintacce ne ga Mutane Masu Lafiya tare da Matsalolin Halitta na CDKN2A?

CDKN2A yana taka muhimmiyar rawa a kimanta haɗarin kansa. Maye gurbi a cikin CDKN2A na iya tarwatsa mahimman hanyoyin sinadarai, gami da Siginar Siginar Kwayoyin Halitta, Matsalolin Zagayewar Halitta da Tantanin halitta, waɗanda ke yin tasiri ga ci gaban kansa. Idan rukunin kwayoyin halittar ku ya bayyana maye gurbi a cikin CDKN2A da ke da alaƙa da Skin Cancer, la'akari da haɗa abubuwan da ake amfani da su na Artemisinine a cikin shirin ku na abinci mai gina jiki. Waɗannan abubuwan kari na iya yin tasiri mai kyau ta hanyoyi kamar Siginar Kwayoyin Halitta, fa'ida ta samar da tallafi mai dacewa ga daidaikun mutane masu maye gurbin CDKN2A da abubuwan da suka shafi lafiya.

a Kammalawa

Abu mafi mahimmanci guda biyu da ya kamata a tuna shine cewa maganin ciwon daji da abinci mai gina jiki ba iri ɗaya bane ga kowa. Abinci mai gina jiki, gami da abinci da kari kamar Artemisinine, kayan aiki ne mai inganci wanda zaku iya sarrafa shi yayin fuskantar cutar kansa.

"Me zan ci?" ita ce tambayar da aka fi yi wa masu fama da cutar kansa da kuma waɗanda ke cikin haɗarin kamuwa da cutar kansa. Amsar da ta dace ita ce ta dogara da dalilai irin su nau'in ciwon daji, kwayoyin halitta na ƙari, jiyya na yanzu, allergies, salon rayuwa, da BMI.

Samun keɓancewar abincin ku don ciwon daji daga addon ta danna hanyar haɗin da ke ƙasa da amsa tambayoyi game da nau'in ciwon daji, jiyya, salon rayuwa, rashin lafiyar ku, shekaru, da jinsi.

References

• cBioPortal don Cancer Genomics
• Gwajin gwaji na hepatoma tare da artemisinin da abubuwan da suka samo asali: in vitro da in vivo ayyukan, chemosensitization, da hanyoyin aiwatarwa.
• cBioPortal don Cancer Genomics
• Cytotoxicity na samfuran halitta da abubuwan haɓaka zuwa ga MCF-7 cell monolayers da ciwon daji-kamar mammospheres.
• Pan-cancer bincike na dukan kwayoyin halitta.
• Hana cyclin E1 yana shawo kan juriya na temozolomide a cikin glioblastoma ta hanyar lalata Mcl-1.
• Artesunate yana haɓaka apoptosis mai haifar da TRAIL a cikin ƙwayoyin carcinoma na mahaifa ta mutum ta hanyar hana hanyoyin siginar NF-κB da PI3K/Akt.
• Yanayin yanayin yanayin glioblastoma.
• Yada manyan ƙwayoyin lymphomas na B-cell tare da sharewar CDKN2A suna da sa hannu na maganganu na musamman da rashin fahimta a ƙarƙashin maganin R-CHOP: nazarin GELA.