Wane ciwon daji ne zai amfana da hada Ruman a cikin abincin su?

labarai

Ruman an san shi sosai don amfanin lafiyar sa kuma masu ciwon daji da waɗanda ke cikin haɗarin ƙwayoyin cuta galibi suna amfani da su. Duk da haka, aminci da ingancin Ruman ga masu fama da ciwon daji ya dogara da abubuwa da yawa kamar alamar ciwon daji, chemotherapy, sauran jiyya, da kwayoyin cutar ciwon daji. Sanin cewa wasu abinci da kari, irin su 'ya'yan innabi da alayyafo, na iya yin mu'amala mara kyau tare da magungunan ciwon daji kuma suna haifar da mummunan halayen yana da mahimmanci.

Abinci yana da mahimmanci don maganin ciwon daji saboda yana iya rinjayar sakamakon jiyya. Masu ciwon daji dole ne su zaɓi a hankali kuma su haɗa abinci da abubuwan da suka dace a cikin abincinsu. Misali, Ruman zai iya amfanar waɗanda ke fama da Tumor Fibrous na Farko waɗanda ke jurewa Avastin, amma bazai yi kyau ba ga marasa lafiya waɗanda ke karɓar Cisplatin don Shugaban Primary da Neck Squamous Cell Carcinoma. Bugu da ƙari kuma, yayin da Ruman zai iya taimaka wa mutane masu haɗarin kwayoyin halitta "ERBB2", ba za a iya ba da shawarar ga waɗanda ke da haɗarin kwayar halitta daban-daban "ERCC2". Keɓance tsare-tsare na abinci bisa lafiya, jiyya, da kwayoyin halitta yana da mahimmanci.

Fahimtar cewa yin yanke shawara kan dacewa da Ruman ga mai ciwon daji yana buƙatar keɓantacce yana da mahimmanci. Mahimman abubuwa kamar nau'in ciwon daji, hanyoyin jiyya, kayan shafa kwayoyin halitta, haɗarin kwayoyin halitta, shekaru, nauyin jiki, da salon rayuwa suna da mahimmanci wajen yanke shawarar ko Ruman shine zaɓin da ya dace. Genetics da genomics, musamman, wani muhimmin la'akari ne. Tun da waɗannan abubuwan na iya haɓakawa, yana da mahimmanci a yi bita akai-akai da daidaita zaɓin abinci don dacewa da canje-canje a matsayin lafiya da magani.

A ƙarshe, cikakkiyar hanya don zaɓin abinci yana da mahimmanci, mai da hankali kan tasirin duk abubuwan da ke aiki a cikin abinci / kari kamar Ruman maimakon tantance kowane sashi mai aiki daban ko yin watsi da shi gaba ɗaya. Wannan faffadan hangen nesa yana haɓaka mafi ma'ana da tsarin kimiyya don tsara tsarin abinci don ciwon daji.

Takaitaccen Bayani

Amfani da kayan abinci da abubuwan gina jiki, irin su bitamin, ganyaye, ma'adanai, probiotics, da ƙari na musamman daban-daban, suna tashi a tsakanin masu cutar kansa. An tsara waɗannan abubuwan kari don sadar da babban taro na takamaiman kayan aiki masu aiki, waɗanda yawancin su ma suna cikin abinci daban-daban. Mahimmanci da bambancin kayan aiki masu aiki sun bambanta tsakanin abinci duka da kari. Abincin yawanci yana ba da kewayon kayan aiki masu aiki amma a ƙananan ƙima, yayin da kari ke ba da babban taro na takamaiman sinadarai.

Yin la'akari da bambance-bambancen ayyukan kimiyya da nazarin halittu na kowane sashi mai aiki a matakin ƙwayoyin cuta, yana da mahimmanci a ƙididdige tasirin haɗin gwiwar waɗannan abubuwan yayin yanke shawarar abinci da kari don ci ko a'a.

Tambaya mai mahimmanci ta taso: Shin yakamata ku haɗa Ruman a cikin abincinku azaman kayan abinci ko kari? Shin yana da kyau ku ci Ruman idan kuna da yanayin ƙwayar cuta zuwa ciwon daji mai alaƙa da kwayar ERBB2? Me zai faru idan a maimakon haka haɗarin kwayoyin ku ya fito ne daga gene ERCC2? Shin yana da fa'ida a haɗa da Ruman a cikin abincinku idan an gano ku da Ciwon Kankara na Farko da Neck Squamous Cell, ko kuma idan ganewar ku shine Tumor Fibrous na Farko? Bugu da ƙari, ta yaya ya kamata a daidaita shan Ruman ku idan kuna shan maganin Avastin ko kuma idan shirin ku ya canza daga Avastin zuwa Cisplatin? Yana da mahimmanci a gane cewa maganganun masu sauƙi kamar 'Ruman na halitta ne, don haka yana da amfani ko da yaushe' ko 'ruman yana ƙarfafa rigakafi' ba su isa ba don zaɓin abinci / ƙarin zaɓi.

Bugu da ƙari, yana da mahimmanci a sake tantance dacewar haɗa da Ruman a cikin abincin ku idan akwai canje-canje a cikin tsarin kula da ku. A taƙaice, lokacin da za ku yanke shawara game da haɗa abinci ko kari kamar Ruman a cikin abincinku don fa'idodinsa, yakamata ku yi la'akari da tasirin sinadarai gabaɗaya na dukkan sinadaran, la'akari da abubuwa kamar nau'in ciwon daji, takamaiman jiyya da kuke sha, yanayin yanayin halitta. , da zabin salon rayuwa.

Cancer

Ciwon daji ya kasance babban ƙalubale a fannin likitanci, galibi yana haifar da damuwa. Duk da haka, ci gaba na baya-bayan nan ya inganta sakamakon jiyya, musamman ta hanyar hanyoyin kulawa na musamman, hanyoyin sa ido mara kyau ta hanyar amfani da jini da samfurori na jini, da haɓakar rigakafi. Ganowa da wuri da shiga tsakani akan lokaci sun kasance masu mahimmanci a cikin tasiri mai tasiri ga sakamakon jiyya gabaɗaya.

Gwajin kwayoyin halitta yana ba da gagarumin alƙawari a kimanta haɗarin cutar kansa da lallacewa da wuri. Koyaya, ga mutane da yawa waɗanda ke da alaƙar dangi da ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙwayar cuta zuwa ciwon daji, zaɓuɓɓukan don shiga tsakani na warkewa, ko da tare da sa ido na yau da kullun, galibi suna iyakance ko babu. Da zarar an gano cutar kansa da wani takamaiman nau'in ciwon daji, kamar Tumor na Fibrous Tumor na Farko ko Primary Head da Neck Squamous Cell Carcinoma, dabarun jiyya suna buƙatar daidaitawa bisa ga ƙwayoyin ƙwayar cuta na mutum, matakin cutar, da kuma abubuwan da suka shafi shekaru da shekaru. jinsi."

Bayan jiyya, ci gaba da sa ido yana da mahimmanci don gano duk wani alamun sake dawowa da ciwon daji da kuma sanar da yanke shawara na gaba. Yawancin masu fama da cutar kansa da waɗanda ke cikin haɗari galibi suna neman shawara kan haɗa wasu abinci da kari a cikin abincinsu, wanda ke taka muhimmiyar rawa a cikin tsarin yanke shawara gabaɗaya game da kula da lafiya.

Tambaya mai mahimmanci ita ce ko za a yi la'akari da haɗarin kwayoyin halitta da takamaiman cututtuka na ciwon daji lokacin yanke shawarar zabin abinci, irin su Ruman. Shin haɗarin kwayoyin halitta don ciwon daji da ke fitowa daga maye gurbi a cikin ERBB2 yana da tasirin hanyoyin sinadarai iri ɗaya kamar maye gurbi a cikin ERCC2? Daga mahangar abinci mai gina jiki, shin haɗarin da ke tattare da Tumor na Fibrous Tumor na Farko ya yi daidai da Ciwon Kankara na Farko da Ƙwayoyin Ƙwayoyin Ƙwayoyin Ƙwayoyin Ƙwayoyin Ƙwayoyin Ƙwaƙwalwa? Bugu da ƙari, shin la'akarin abincin ya kasance iri ɗaya ga waɗanda ke jurewa Cisplatin kamar waɗanda ke karɓar Avastin? Waɗannan la'akari suna da mahimmanci wajen yin ingantaccen zaɓin abinci ga mutanen da ke da haɗarin ƙwayoyin cuta daban-daban da magungunan kansa.

Ruman - Ƙarin Gina Jiki

Ƙarin Ruman ya ƙunshi nau'ikan sinadarai masu aiki, ciki har da Octadecanoic Acid, Hexadecanoic Acid, Betulinic Acid, Casuarinin da Ursolic Acid, kowannensu yana samuwa a wurare daban-daban. Wadannan sinadarai suna tasiri hanyoyin kwayoyin halitta, musamman MYC Signaling, Epithelial to Mesenchymal Transition, PI3K-AKT-MTOR Signaling da Chromatin Remodeling, wanda ke tsara mahimman abubuwan ciwon daji a matakin salula, kamar haɓakar ƙwayar cuta, yadawa, da mutuwar kwayar halitta. Ganin wannan tasirin ilimin halitta, zaɓin abubuwan da suka dace kamar Ruman, shi kaɗai ko a hade, ya zama yanke shawara mai mahimmanci a cikin mahallin abinci mai gina jiki na kansa. Lokacin yin la'akari da amfani da Ruman don ciwon daji, yana da mahimmanci a yi la'akari da waɗannan abubuwa da hanyoyi daban-daban. Wannan shi ne saboda, kama da maganin ciwon daji, yin amfani da Ruman ba yanke shawara ba ne na duniya wanda ya dace da dukan ciwon daji amma yana buƙatar zama na musamman.

Zabar Kariyar Ruman

Magana da tambayar 'Yaushe zan guje wa Ruman a cikin mahallin Ciwon daji' yana da kalubale saboda amsar ita ce ta musamman - kawai 'Ya dogara!'. Kamar yadda duk wani maganin ciwon daji bazai yi tasiri ga kowane majiyyaci ba, dacewa da aminci ko amfanin Ruman ya bambanta dangane da yanayin mutum. Abubuwa irin su takamaiman nau'in ciwon daji, ƙayyadaddun kwayoyin halitta, jiyya na yanzu, sauran abubuwan da ake amfani da su, yanayin salon rayuwa, BMI, da duk wani rashin lafiyan duk suna taka rawa wajen tantance ko Ruman ya dace ko ya kamata a kauce masa, yana mai jaddada mahimmancin la'akari da keɓaɓɓen irin wannan yanke shawara.

1. Shin Kariyar Ruman za su amfana da Jikin Farko da Wuyan Ciwon Cisplatin?

Babban Head da Neck Squamous Cell Carcinoma yana da alaƙa da maye gurbi na musamman, wato FRG1BP, TP53 da PCDH11X, waɗanda ke haifar da sauye-sauye a cikin hanyoyin sinadarai, musamman Epithelial zuwa Canjin Mesenchymal, Matsalolin Zagayewar Tantanin halitta da Apoptosis. Tasirin maganin ciwon daji, kamar Cisplatin, ya dogara ne akan tsarin aikinsa akan waɗannan takamaiman hanyoyin. Kyakkyawan dabarar ta ƙunshi daidaita aikin jiyya tare da hanyoyin da ke haifar da ciwon daji, ta yadda za a tabbatar da keɓaɓɓen hanya mai inganci. A cikin irin wannan yanayin, guje wa abinci ko abubuwan gina jiki waɗanda zasu iya magance tasirin jiyya ko rage wannan jeri yana da mahimmanci. Misali, kari na Ruman, wanda ke shafar Epithelial zuwa Mesenchymal Transition, maiyuwa ba zai zama zabin da ya dace ba a yanayin cutar sankarau na Primary Head da Neck Squamous Cell Carcinoma lokacin shan Cisplatin. Wannan saboda yana iya ko dai ya tsananta ci gaban cutar ko kuma ya tsoma baki cikin ingancin maganin. Lokacin zabar tsarin abinci mai gina jiki, yana da mahimmanci a yi la'akari da abubuwa kamar nau'in ciwon daji, jiyya masu gudana, shekaru, jinsi, BMI, salon rayuwa, da duk wani sanannen maye gurbi.

2. Shin Kariyar Ruman za su amfana da Marasa lafiya na Fibrous Tumor na Farko waɗanda ke jure wa Avastin Jiyya?

Tumor na Fibrous na Farko na Farko ana gano shi ta takamaiman maye gurbi, kamar BRD4, FLI1 da KMT2C, wanda ke haifar da canje-canje a hanyoyin sinadarai, musamman siginar MYC, Gyaran Chromatin, Gyaran DNA, Oncogenic Histone Methylation da Amino Acid Metabolism. Ingancin maganin ciwon daji, kamar Avastin, an ƙaddara ta hanyar hulɗar sa tare da waɗannan hanyoyin. Manufar ita ce a tabbatar da cewa maganin ya dace daidai da hanyoyin da ke haifar da ciwon daji, yana ba da damar tsarin kulawa na musamman. A cikin wannan mahallin, abinci ko kari waɗanda suka dace da jiyya ko haɓaka wannan jeri ya kamata a yi la'akari da su. Misali, kari na Ruman wani zaɓi ne na hankali ga waɗanda ke da Tumor Fibrous na Farko na Farko da ke jurewa Avastin. Wannan saboda Ruman yana tasiri hanyoyi kamar MYC Signaling, wanda zai iya ko dai ya hana abubuwan da ke haifar da Tumor na Fibrous na Primary Solitary ko amfana da tasirin Avastin.

3. Shin Kariyar Ruman Aminci ne ga Mutane masu Lafiya tare da Haɗin Halittar Halitta na ERCC2?

Kamfanoni daban-daban suna ba da kwatancen kwayoyin halitta don tantance haɗarin kwayoyin cutar kansa daban-daban. Wadannan bangarori sun hada da kwayoyin halittar da ke da alaka da nono, ovarian, uterine, prostate, da ciwon daji na ciki. Gwajin waɗannan kwayoyin halitta na iya tabbatar da ganewar asali da kuma sanar da magani da dabarun gudanarwa. Gano bambance-bambancen da ke haifar da cututtuka na iya ƙara taimakawa a gwaji da gano dangin da ke cikin haɗari. Halin ERCC2 yawanci ana haɗa shi a cikin waɗannan bangarorin don kimanta haɗarin kansa.

Maye gurbi a cikin kwayar halittar ERCC2 yana shafar hanyoyin biochemical ko matakai, kamar siginar siginar PI3K-AKT-MTOR da Gyaran DNA, waɗanda ke da hannu kai tsaye ko a kaikaice wajen tuƙi ciwon daji a matakin ƙwayoyin cuta. Lokacin da rukunin kwayoyin halitta ya gano maye gurbi a cikin ERCC2 da ke da alaƙa da haɗarin Ciwon Skin Skin, dalilin kimiyya ya ba da shawarar guje wa amfani da ƙarin Ruman. Wannan saboda ƙarin Ruman yana tasiri hanyoyi kamar siginar PI3K-AKT-MTOR, wanda zai iya haifar da mummunan tasiri a cikin mahallin maye gurbi na ERCC2 da yanayin ciwon daji masu alaƙa.

4. Shin Kariyar Ruman lafiya ne ga Mutane masu lafiya tare da Mutuwar ERBB2 Haɗarin Halitta?

ERBB2 yana taka muhimmiyar rawa a kimanta haɗarin cutar kansa. Maye gurbi a cikin ERBB2 na iya tarwatsa mahimman hanyoyin sinadarai, gami da Gyaran Chromatin, Siginar Factor Factor da Siginar PI3K-AKT-MTOR, waɗanda ke tasiri ga ci gaban kansa. Idan rukunin kwayoyin halittar ku ya bayyana maye gurbi a cikin ERBB2 da ke da alaƙa da Esophageal Adenocarcinoma, la'akari da haɗa kayan kariyar Ruman a cikin shirin ku na abinci mai gina jiki. Waɗannan abubuwan kari na iya yin tasiri ga hanyoyin kamar Chromatin Remodeling, fa'ida ta samar da tallafi mai dacewa ga daidaikun mutane masu maye gurbin ERBB2 da abubuwan da suka shafi lafiya.

a Kammalawa

Abu mafi mahimmanci guda biyu da ya kamata a tuna shine cewa maganin ciwon daji da abinci mai gina jiki ba iri ɗaya bane ga kowa. Abinci mai gina jiki, gami da abinci da kari kamar Ruman, kayan aiki ne mai inganci wanda zaku iya sarrafa shi yayin fuskantar cutar kansa.

"Me zan ci?" ita ce tambayar da aka fi yi wa masu fama da cutar kansa da kuma waɗanda ke cikin haɗarin kamuwa da cutar kansa. Amsar da ta dace ita ce ta dogara da dalilai irin su nau'in ciwon daji, kwayoyin halitta na ƙari, jiyya na yanzu, allergies, salon rayuwa, da BMI.

Samun keɓancewar abincin ku don ciwon daji daga addon ta danna hanyar haɗin da ke ƙasa da amsa tambayoyi game da nau'in ciwon daji, jiyya, salon rayuwa, rashin lafiyar ku, shekaru, da jinsi.

References

• Matsakaicin yanayin cutar kansar ƙanƙara da aka bayyana daga jerin masu zuwa na asibiti na marasa lafiya 10,000.
• cBioPortal don Cancer Genomics
• Pan-cancer bincike na dukan kwayoyin halitta.
• Shigar da kama sake zagayowar tantanin halitta da apoptosis a cikin ɗan adam wanda ba ƙaramin ƙwayar cutar kansar huhu A549 ta casuarinin daga haushin Terminalia arjuna Linn.
• cBioPortal don Cancer Genomics
• Matsayin microenvironment na tumor a cikin juriya ga maganin anti-angiogenic.