Abinci don Mucinous Colorectal Adenocarcinoma!

Gabatarwa

Abinci don Mucinous Colorectal Adenocarcinoma ya kamata a keɓance shi ga kowane mutum kuma dole ne ya daidaita lokacin da maganin ciwon daji ko ƙwayar ƙwayar cuta ta canza. Keɓancewa da daidaitawa dole ne suyi la'akari da duk abubuwan da ke aiki ko abubuwan halitta waɗanda ke ƙunshe a cikin abinci daban-daban dangane da ilmin halitta na nama, kwayoyin halitta, jiyya, yanayin salon rayuwa da zaɓin abinci. Don haka yayin da abinci mai gina jiki yana ɗaya daga cikin yanke shawara mai mahimmanci ga mai ciwon daji da kuma wanda ke cikin haɗarin cutar kansa don yin - yadda za a zaɓi abincin da za a ci ba abu ne mai sauƙi ba.

Mucinous adenocarcinoma na yankin colorectal, wani nau'in nau'in ciwon daji na launin fata, yana bayyana ta hanyar samar da mucin a cikin ƙwayoyin tumor. Kwayoyin cututtuka na mucinous colorectal adenocarcinoma suna ba da mahimman bayanai game da sifofin tarihi na musamman, suna bambanta shi da sauran nau'in ciwon daji na colorectal. Wannan nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'in nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i nau'i) nau'i-nau'i-nau'i-nau'i-nau'i-nau'i na nuna canje-canje a cikin dabi'un hanji, ciwon ciki,da zub da jini na dubura,wadanda su ne mahimmin alamomi don ci gaba da gwaje-gwajen bincike. Adenocarcinoma mai launi mai launi yana buƙatar kimantawa a hankali, sau da yawa ya haɗa da haɗuwa da gwaje-gwajen hoto da gwajin adenocarcinoma na mucinous launi, kamar biopsy, don tabbatar da ganewar asali. Hanyar magani don ciwon daji na adenocarcinoma na mucinous yawanci ya haɗa da haɗin tiyata, chemotherapy, kuma a wasu lokuta, maganin radiation, ya danganta da matakin ciwon daji da kuma lafiyar lafiyar mai haƙuri. Gudanarwa da tsinkaye na adenocarcinoma mai launi na mucinous sun dogara ne akan ganowa da wuri da kuma tasiri na tsarin kulawa, yana nuna mahimmancin dubawa na yau da kullum da gaggawar kulawar likita don alamun gastrointestinal.

Ga Mucinous Colorectal Adenocarcinoma ko menene kayan lambu, 'ya'yan itatuwa, kwayoyi, iri da mutum ke ci?

Tambayar abinci mai gina jiki ta gama gari wacce masu cutar kansa da daidaikun mutane ke haɗarin kamuwa da cutar kansa ita ce - ga cututtukan daji kamar Mucinous Colorectal Adenocarcinoma shin yana da mahimmancin abincin da nake ci da wanda ba ni? Ko kuma idan na bi tsarin abinci na tushen shuka ya isa ga ciwon daji kamar Mucinous Colorectal Adenocarcinoma?

Misali shin yana da mahimmanci idan an fi cinye kayan lambu Farin kabeji idan aka kwatanta da Turnip? Shin yana da wani bambanci idan an fifita 'ya'yan itacen Pummelo akan Black Mulberry? Haka kuma idan aka yi irin wannan zabin na goro/ iri irin su Butternut akan Kirjin Turawa da kuma nau'in nau'i kamar Broad Bean akan Lima Bean. Kuma idan abin da nake ci yana da mahimmanci - to ta yaya mutum zai gano abincin da aka ba da shawarar ga Mucinous Colorectal Adenocarcinoma kuma amsar iri ɗaya ce ga kowa da kowa da ke da irin wannan ganewar asali ko haɗarin kwayoyin halitta?

Ee! Abincin da kuke ci yana da mahimmanci ga Mucinous Colorectal Adenocarcinoma!

Shawarwari na abinci bazai zama iri ɗaya ga kowa ba kuma yana iya bambanta ko da don ganewar asali iri ɗaya da haɗarin kwayoyin halitta.

Duk abinci (kayan lambu, 'ya'yan itatuwa, goro, tsaba, ƙwaya, mai da sauransu) da kuma abubuwan gina jiki sun ƙunshi fiye da ɗaya kayan aikin kwayoyin halitta ko bio-actives a cikin ma'auni da yawa. Kowane sashi mai aiki yana da tsarin aiki na musamman - wanda zai iya zama kunnawa ko hana hanyoyin sinadarai daban-daban. Abincin da aka bayyana kawai da kari waɗanda aka ba da shawarar su ne waɗanda ba sa haifar da haɓakar ƙwayoyin cutar kansa amma rage su. In ba haka ba bai kamata a ba da shawarar abincin ba. Abinci ya ƙunshi abubuwa masu aiki da yawa - don haka lokacin kimanta abinci da kari kuna buƙatar la'akari da tasirin duk abubuwan da ke aiki gabaɗaya maimakon ɗaiɗaiku.

Misali Pummelo yana dauke da sinadarin Quercetin, Curcumin, Apigenin, Lycopene, Delphinidin. Kuma Black Mulberry yana ƙunshe da sinadarai masu aiki Quercetin, Curcumin, Apigenin, Delphinidin, Myricetin da dai sauransu.

Kuskure na yau da kullun da aka yi lokacin yanke shawara da zabar abincin da za a ci don Mucinous Colorectal Adenocarcinoma - shine kimanta zaɓaɓɓun kayan aikin da ke ƙunshe a cikin abinci kawai kuma watsi da sauran. Saboda nau'ikan nau'ikan aiki daban-daban waɗanda ke ƙunshe a cikin abinci na iya yin tasiri mai adawa akan direbobin cutar kansa - ba za ku iya ceri ɗaukar kayan aiki masu aiki a cikin abinci da kari don yanke shawarar abinci mai gina jiki ga Mucinous Colorectal Adenocarcinoma.

E - ABINCIN ZABIN CUTAR CANCER. DOLE NE HUKUNCIN GINDI HUKUNCIN YI LA'akari da DUKKAN RA'AYIN KAYAN ABINCI.

Ƙwarewar da ake buƙata don Keɓancewar Gina Jiki don Mucinous Colorectal Adenocarcinoma?

Keɓaɓɓen abinci mai gina jiki don ciwon daji kamar Mucinous Colorectal Adenocarcinoma ya ƙunshi shawarwarin abinci / kari; abinci / kari ba a ba da shawarar ba tare da misalin girke-girke waɗanda ke ba da fifikon amfani da shawarar abinci. Ana iya ganin misali na keɓaɓɓen abinci mai gina jiki a wannan mahada.

Yanke shawarar waɗanne abinci ake ba da shawarar ko a'a yana da rikitarwa sosai, yana buƙatar ƙwarewa a cikin Mucinous Colorectal Adenocarcinoma biology, kimiyyar abinci, ilimin halittu, ilimin halittar jiki tare da kyakkyawar fahimtar yadda jiyya na ciwon daji ke aiki da raunin da ke tattare da su wanda jiyya na iya daina yin tasiri.

KARAMAR ƙwararrun ƙwararrun ILMI DA AKE BUKATA DOMIN CIWON GINDI DOMIN CANCER SU NE: CIWON CIWON CIWON CIWON CIWON KIMIYYAR ABINCI, MAGANIN CANCER DA HALITTU.

Halayen cututtukan daji kamar Mucinous Colorectal Adenocarcinoma

Duk cututtukan daji kamar Mucinous Colorectal Adenocarcinoma ana iya siffanta su ta hanyar keɓaɓɓen saitin hanyoyin sinadarai - hanyoyin sa hannu na Mucinous Colorectal Adenocarcinoma. Hanyoyin sinadarai kamar RAS-RAF Signaling, DNA Repair, Small Molecule Transport, PI3K-AKT-MTOR Sigina wani ɓangare ne na ma'anar sa hannu na Mucinous Colorectal Adenocarcinoma. Kwayoyin halittar kansa na kowane mutum na iya bambanta kuma saboda haka takamaiman sa hannun kansa na iya zama na musamman.

Magungunan da ke da tasiri ga Mucinous Colorectal Adenocarcinoma suna buƙatar sanin hanyoyin sa hannun sinadarai masu alaƙa ga kowane mai cutar kansa da mutum cikin haɗarin ƙwayoyin cuta. Don haka jiyya daban-daban tare da hanyoyin ayyuka daban-daban suna da tasiri ga marasa lafiya daban-daban. Hakazalika kuma saboda dalilai guda abinci da kari suna buƙatar keɓancewa ga kowane mutum. Don haka ana ba da shawarar wasu abinci da kari ga Mucinous Colorectal Adenocarcinoma lokacin shan maganin cutar kansa Cetuximab, kuma ba a ba da shawarar wasu abinci da kari ba.

Sources kamar cBioPortal da wasu da yawa suna ba da wakilin majiyyaci bayanan da ba a san su ba daga gwajin asibiti don duk alamun cutar kansa. Wannan bayanan ya ƙunshi cikakkun bayanai na binciken gwaji na asibiti kamar girman samfurin / adadin marasa lafiya, ƙungiyoyin shekaru, jinsi, ƙabila, jiyya, wurin ƙari da kowane maye gurbi.

APC, KRAS, GNAS, KMT2D da KDR sune manyan kwayoyin halittar da aka ruwaito na Mucinous Colorectal Adenocarcinoma. An ba da rahoton APC a cikin kashi 15.2% na wakilan marasa lafiya a duk gwajin asibiti. Kuma an ba da rahoton KRAS a cikin 13.0%. Haɗin bayanan majiyyatan yawan jama'a sun rufe shekaru daga 34 zuwa 81. 50.0% na bayanan haƙuri an gano su a matsayin maza. Mucinous Colorectal Adenocarcinoma ilmin halitta tare da rahotannin kwayoyin halitta tare da bayyana yawan sa hannu kan hanyoyin biochemical don wannan ciwon daji. Idan kwayoyin cutar kansar kansa guda ɗaya ko kuma kwayoyin halittar da ke ba da gudummawar haɗarin kuma an san su to hakan kuma yakamata a yi amfani da shi don keɓanta abinci mai gina jiki.

ZABEN CIWON GINDI YA KAMATA YA YI DAIDAI DA SAHANIN CANCER KOWANNE MUTUM.

Abinci da kari don Mucinous Colorectal Adenocarcinoma

Ga masu ciwon daji

Masu fama da ciwon daji a kan jiyya ko a kan kula da jin dadi suna buƙatar yanke shawara game da abinci da kari - don abubuwan da ake buƙata na adadin kuzari na abinci, don sarrafa duk wani tasiri na jiyya da kuma inganta lafiyar ciwon daji. Duk abinci na tushen tsire-tsire ba daidai ba ne kuma zaɓi da ba da fifikon abinci waɗanda ke keɓantacce kuma aka keɓance su don maganin ciwon daji mai gudana yana da mahimmanci da rikitarwa. Anan akwai wasu misalan da ke ba da ƙa'idodi don yanke shawarar abinci mai gina jiki.

Zabi CAULIFLOWER ko TURNIP?

Farin kabeji na kayan lambu yana ƙunshe da abubuwa masu aiki da yawa ko abubuwan halitta kamar Curcumin, Delphinidin, Isoliquiritigenin, Formononetin, Phloretin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar MAPK Signaling, Metastasis, Carbohydrate Metabolism da Amino Acid Metabolism da sauransu. Farin kabeji ana ba da shawarar ga Mucinous Colorectal Adenocarcinoma lokacin da ci gaba da maganin ciwon daji shine Cetuximab. Wannan saboda Farin kabeji yana canza waɗancan hanyoyin sinadarai waɗanda aka ruwaito a kimiyance don faɗakar da tasirin Cetuximab.

Wasu daga cikin sinadirai masu aiki ko ƙwayoyin cuta a cikin kayan lambu na Turnip sune Quercetin, Ellagic Acid, Curcumin, Delphinidin, Caffeic Acid. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na biochemical kamar WNT Beta Catenin Signaling, Extracellular Matrix Remodeling da Epithelial zuwa Mesenchymal Transition da sauransu. Ba a ba da shawarar turnip don Mucinous Colorectal Adenocarcinoma lokacin da ake ci gaba da maganin cutar kansa Cetuximab saboda yana canza waɗancan hanyoyin sinadarai waɗanda ke sa maganin kansa ya jure ko rashin jin daɗi.

ANA SHAWARAR BONON GONUWA KAN JUYA DOMIN MAGANIN CETUREXIMAB.

Zabi 'Ya'yan itace BLACK MULBERRY ko PUMMELO?

Black Mulberry 'ya'yan itace yana ƙunshe da abubuwa masu aiki da yawa ko abubuwan da suka shafi rayuwa kamar Quercetin, Curcumin, Apigenin, Delphinidin, Myricetin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar MAPK Signaling, Metastasis, Lipid Metabolism and Growth Factor Signaling da sauransu. Ana ba da shawarar Black Mulberry don Mucinous Colorectal Adenocarcinoma lokacin da ci gaba da maganin ciwon daji shine Cetuximab. Wannan saboda Black Mulberry yana canza waɗancan hanyoyin sinadarai waɗanda aka ruwaito a kimiyance don faɗakar da tasirin Cetuximab.

Wasu daga cikin sinadirai masu aiki ko bioactives a cikin 'ya'yan itace Pummelo sune Quercetin, Curcumin, Apigenin, Lycopene, Delphinidin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar WNT Beta Catenin Signaling, Epithelial to Mesenchymal Transition da PI3K-AKT-MTOR Signaling da sauransu. Ba a ba da shawarar Pummelo don Mucinous Colorectal Adenocarcinoma lokacin da ake ci gaba da jinyar cutar kansa Cetuximab saboda yana canza waɗancan hanyoyin sinadarai waɗanda ke sa maganin kansa ya jure ko ƙasa da martani.

ANA SHAWARAR YAR UWA BLACK MULBERRY AKAN PUMMELO DOMIN MAGANIN CETIXIMAB.

Zabi Gyada BUTTERNUT ko TURAWA KIRJI?

Butternut yana ƙunshe da sinadarai masu aiki da yawa ko abubuwan da suka shafi rayuwa kamar Curcumin, Apigenin, Lycopene, Delphinidin, Myricetin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar siginar MAPK, Gyaran DNA, Junction Adherens da Amino Acid Metabolism da sauransu. Ana ba da shawarar Butternut don Mucinous Colorectal Adenocarcinoma lokacin da ci gaba da maganin ciwon daji shine Cetuximab. Wannan saboda Butternut yana canza waɗannan hanyoyin sinadarai waɗanda aka ruwaito a kimiyance don fahimtar tasirin Cetuximab.

Wasu daga cikin sinadirai masu aiki ko abubuwan da ke cikin ƙirjin ƙirjin na Turai sune Quercetin, Ellagic Acid, Curcumin, Apigenin, Delphinidin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar WNT Beta Catenin Signaling, Epithelial to Mesenchymal Transition da PI3K-AKT-MTOR Signaling da sauransu. Ba a ba da shawarar ƙirjin ƙirji na Turai don Mucinous Colorectal Adenocarcinoma lokacin da ake ci gaba da jinyar cutar kansa Cetuximab saboda yana canza waɗancan hanyoyin sinadarai waɗanda ke sa maganin kansa ya jure ko kuma ba ya da ƙarfi.

ANA SHAWARAR GASKIYA A KAN KIRJIN TURAI DOMIN MAGANIN CETUCIMAB.

Ga Mutanen da ke da Hatsarin Halitta na Ciwon daji

Tambayar da mutanen da ke da haɗarin ƙwayoyin cuta na Mucinous Colorectal Adenocarcinoma ko tarihin iyali suka yi ita ce "Me zan ci dabam da da?" da kuma yadda yakamata su zaɓi abinci da kari don sarrafa haɗarin cutar. Tun da haɗarin ciwon daji babu wani abu da za a iya aiwatar da shi dangane da jiyya - yanke shawara na abinci da kari sun zama mahimmanci kuma ɗayan kaɗan ne kawai abubuwan da za a iya yi. Duk kayan abinci na tushen tsire-tsire ba daidai ba ne kuma sun dogara ne akan gano kwayoyin halitta da sa hannun hanya - zaɓin abinci da kari ya kamata a keɓance na keɓaɓɓu.

Zabi GIANT BUTTERBUR ko ARROWROOT?

Giant Butterbur na kayan lambu yana ƙunshe da abubuwa masu aiki da yawa ko abubuwan da suka shafi rayuwa kamar Curcumin, Apigenin, Delphinidin, Lupeol, Myricetin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar MAPK Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling da Oxidative Stress da sauransu. Ana ba da shawarar Giant Butterbur don haɗarin Mucinous Colorectal Adenocarcinoma lokacin da haɗarin ƙwayoyin cuta ke da alaƙa shine APC. Wannan saboda Giant Butterbur yana haɓaka waɗancan hanyoyin sinadarai waɗanda ke fuskantar sa hannun direbobin sa.

Wasu daga cikin sinadirai masu aiki ko bioactives a cikin kayan lambu Arrowroot sune Quercetin, Curcumin, Apigenin, Delphinidin, Lupeol. Waɗannan sinadirai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar Siginar Kwayoyin Halitta da Damuwar Oxidative da sauransu. Arrowroot ba a ba da shawarar lokacin da haɗarin Mucinous Colorectal Adenocarcinoma lokacin da haɗarin ƙwayoyin cuta ke da alaƙa shine APC saboda yana haɓaka hanyoyin sa hannu.

ANA SHAWARAR GANGAR GIRMAN BUTTERBUR A KAN KIBA GA JAM'IYYAR APC NA KASAR CANCER.

Zabi Fruit NANCE ko Lime?

Fruit Nance yana ƙunshe da abubuwa da yawa masu aiki ko abubuwan halitta kamar Curcumin, Apigenin, Delphinidin, Lupeol, Myricetin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar MAPK Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling da Oxidative Stress da sauransu. Ana ba da shawarar Nance don haɗarin Mucinous Colorectal Adenocarcinoma lokacin da haɗarin ƙwayoyin cuta ke da alaƙa shine APC. Wannan saboda Nance yana haɓaka waɗancan hanyoyin sinadarai waɗanda ke fuskantar sa hannun direbobin sa.

Wasu daga cikin sinadirai masu aiki ko bioactives a cikin 'ya'yan itace Lemun tsami sune Curcumin, Delphinidin, Lupeol, Caffeine, Formononetin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar Oxidative Stress da sauransu. Ba a ba da shawarar lemun tsami ba lokacin da haɗarin Mucinous Colorectal Adenocarcinoma lokacin da haɗarin ƙwayoyin cuta ke da alaƙa shine APC saboda yana haɓaka hanyoyin sa hannu.

ANA SHAWARAR FRUIT NANCE AKAN RUWAN RUWAN RUWA GA JAM'IYYAR APC NA KASAR CANCER.

Zabi Gyada COMMON HAZELNUT ko KIRJI?

Hazelnut na gama gari ya ƙunshi abubuwa masu aiki da yawa ko abubuwan da ke amfani da su kamar Quercetin, Curcumin, Delphinidin, Lupeol, Myricetin. Waɗannan sinadarai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar MAPK Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling da Oxidative Stress da sauransu. Ana ba da shawarar Hazelnut na gama-gari don haɗarin Mucinous Colorectal Adenocarcinoma lokacin da haɗarin ƙwayoyin cuta ke da alaƙa shine APC. Wannan saboda Common Hazelnut yana ƙara waɗancan hanyoyin sinadarai waɗanda ke fuskantar sa hannun direbobin sa.

Wasu daga cikin sinadirai masu aiki ko ƙwayoyin cuta a cikin Chestnut sune Ellagic Acid, Curcumin, Apigenin, Delphinidin, Lupeol. Waɗannan sinadirai masu aiki suna sarrafa hanyoyi daban-daban na sinadarai kamar Siginar Kwayoyin Halitta da Damuwar Oxidative da sauransu. Ba a ba da shawarar Chestnut ba lokacin da haɗarin Mucinous Colorectal Adenocarcinoma lokacin da haɗarin ƙwayoyin cuta ke da alaƙa shine APC saboda yana haɓaka hanyoyin sa hannu.

ANA SHAWARAR HANYAR GASKIYA A KAN KIRJI GA JAM'IYYAR APC NA KASAR CANCER.

a Kammalawa

Abinci da Kari da aka zaɓa sune mahimman yanke shawara don ciwon daji kamar Mucinous Colorectal Adenocarcinoma. Mucinous Colorectal Adenocarcinoma marasa lafiya da kuma daidaikun mutanen da ke da haɗarin kwayoyin halitta koyaushe suna da wannan tambayar: "Waɗanne abinci ne da abubuwan gina jiki da aka ba ni shawarar kuma waɗanda ba su da kyau?" Akwai imani gama gari wanda shine kuskuren cewa duk abincin da ake amfani da shi na shuka zai iya zama mai fa'ida ko a'a amma ba zai zama cutarwa ba. Wasu abinci da kari na iya tsoma baki tare da jiyya na ciwon daji ko haɓaka hanyoyin kwayoyin cutar kansa.

Akwai nau'ikan alamun ciwon daji daban-daban kamar Mucinous Colorectal Adenocarcinoma, kowannensu yana da nau'ikan ƙwayoyin cuta daban-daban tare da ƙarin bambancin genomic a kowane mutum. Bugu da ari kowane maganin ciwon daji da chemotherapy yana da tsarin aiki na musamman. Kowane abinci kamar Farin kabeji ya ƙunshi nau'o'in bioactives daban-daban a cikin adadi daban-daban, waɗanda ke da tasiri akan nau'ikan hanyoyin sinadarai daban-daban. Ma'anar abinci mai gina jiki na keɓaɓɓen shawarwarin abinci ne na keɓantacce don alamun cutar kansa, jiyya, kwayoyin halitta, salon rayuwa da sauran dalilai. Hukunce-hukuncen keɓancewar abinci mai gina jiki don ciwon daji na buƙatar sanin ilimin halittar kansa, kimiyyar abinci da fahimtar nau'ikan jiyya na chemotherapy. A ƙarshe lokacin da aka sami canje-canjen jiyya ko kuma an gano sabbin kwayoyin halitta - keɓancewar abinci mai gina jiki yana buƙatar sake kimantawa.

Maganin keɓancewar abinci mai gina jiki na addon ya sa yanke shawara cikin sauƙi kuma yana cire duk zato a cikin amsa tambayar, "Waɗanne abinci ne zan zaɓa ko ban zaɓa don Mucinous Colorectal Adenocarcinoma?". Ƙungiyoyin horo da yawa na addon sun haɗa da likitocin ciwon daji, masana kimiyya na asibiti, injiniyoyin software da masana kimiyyar bayanai.

References

• CrcD 2022
• Pan-cancer bincike na dukan kwayoyin halitta.
• Brassinin yana hana hanyar siginar STAT3 ta hanyar daidaitawa na PIAS-3 da SOCS-3 magana kuma yana wayar da kan ɗan adam ciwon huhu xenograft a cikin tsirara mice zuwa paclitaxel.
• α-Terpineol yana rage ciwon ciwon daji ta hanyar daidaitawa na damuwa na oxidative da hanawa na iNOS.