addonfinal2
What Foods are Recommended for Cancer?
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.

Which Foods are Recommended for Mucinous Ovarian Cancer?

Sep 7, 2022

4.7
(26)
Estimated reading time: 15 minutes
Home » Blogs » Which Foods are Recommended for Mucinous Ovarian Cancer?

Highlights

No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Mucinous Ovarian Cancer when undergoing chemotherapy or when you determine you have a genetic risk for developing Mucinous Ovarian Cancer because of SMAD4 and CDKN2A gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.

There is no one answer to this question for cancers such as Mucinous Ovarian Cancer which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.

In short – the process to answer questions like “Should I Avoid eating fruit Pummelo” or “Include fruit Quince in my diet” or “Should I reduce consumption of vegetable Radish” or “Can I take Modified Citrus Pectin and Senna supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.

RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO MUCINOUS OVARIAN CANCER, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.

The overall objective of personalized nutrition for Mucinous Ovarian Cancer is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.

RECOMMENDATION: UPDATE YOUR NUTRITION FOR MUCINOUS OVARIAN CANCER, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.



About Mucinous Ovarian Cancer

cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.

Following key highlights are derived from clinical data for Mucinous Ovarian Cancer from cBioPortal. From a patient sample size of 19; the top genes with mutations and other abnormalities for Mucinous Ovarian Cancer include genes KRAS, TP53, PIK3CA, SMAD4 and CDKN2A. The occurrence frequency distribution for these genes respectively is 54.5%, 54.5%, 18.2%, 18.2% and 18.2%. These tumor genetic details of Mucinous Ovarian Cancer are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Mucinous Ovarian Cancer.

Significance of Nutrition for Mucinous Ovarian Cancer

All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Mucinous Ovarian Cancer. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.

For example Pummelo includes active ingredients Naringin, Beta-sitosterol, Vitamin C, Oleic Acid, Linolenic Acid and others. And Quince contains active ingredients Modified Citrus Pectin, Oleic Acid, Vitamin C, Quercitrin, Chlorogenic Acid and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.

For cancers like Mucinous Ovarian Cancer, activation or inhibition of selected biochemical pathways like PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints, MAPK Signaling, Cell Cycle plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Mucinous Ovarian Cancer, while eating some other foods and supplements may not be recommended.

One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

For cancers like Mucinous Ovarian Cancer, activation or inhibition of selected biochemical pathways like PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints, MAPK Signaling, Cell Cycle plays an important role in driving cancer growth.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR MUCINOUS OVARIAN CANCER – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.

Foods for Mucinous Ovarian Cancer undergoing chemotherapy treatment

In Mucinous Ovarian Cancer – the genes KRAS, TP53, PIK3CA, SMAD4 and CDKN2A have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Mucinous Ovarian Cancer are PI3K-AKT-MTOR Signaling and others. Nivolumab is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers PI3K-AKT-MTOR Signaling so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.

RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.

Eat more pulses, Mung Bean or Soy Bean?

Pulses are an important part of many diets. The active ingredients contained in Mung Bean are Glucaric Acid, Oleic Acid, Vitamin C, Linolenic Acid, Quercetin among others. While the active ingredients contained in Soy Bean are Lupeol, Daidzein, Beta-sitosterol, Vitamin E, Vitamin C and others.

Glucaric Acid can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Vitamin C has biological action on biochemical pathways WNT Beta Catenin Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling.

Lecithin can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Rutin has biological action on biochemical pathways WNT Beta Catenin Signaling. And so on.

When treating Mucinous Ovarian Cancer with chemotherapy Nivolumab – Foods like Mung Bean are recommended compared to Soy Bean. This is because the active ingredients Lecithin and Rutin in Soy Bean interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Glucaric Acid and Vitamin C contained in Mung Bean support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: MUNG BEAN IS RECOMMENDED OVER SOY BEAN FOR MUCINOUS OVARIAN CANCER ON TREATMENT WITH CHEMOTHERAPY NIVOLUMAB FOR SOME CONDITIONS.

Eat more vegetables, Arugula or Radish?

Vegetables are an important part of many diets. The active ingredients contained in Arugula are Esculin, Kaempferol, Vitamin A, Vitamin K, Erysolin among others. While the active ingredients contained in Radish are Isorhamnetin, Beta-sitosterol, Vitamin C, Oleic Acid, Linolenic Acid and others.

Kaempferol can manipulate biochemical pathways WNT Beta Catenin Signaling and PI3K-AKT-MTOR Signaling. Vitamin A has biological action on biochemical pathways MYC Signaling, WNT Beta Catenin Signaling and PI3K-AKT-MTOR Signaling.

Pelargonidin can manipulate biochemical pathways WNT Beta Catenin Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling. Folic Acid has biological action on biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. And so on.

When treating Mucinous Ovarian Cancer with chemotherapy Nivolumab – Foods like Arugula are recommended compared to Radish. This is because the active ingredients Pelargonidin and Folic Acid in Radish interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Kaempferol and Vitamin A contained in Arugula support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: ARUGULA IS RECOMMENDED OVER RADISH FOR MUCINOUS OVARIAN CANCER ON TREATMENT WITH CHEMOTHERAPY NIVOLUMAB FOR SOME CONDITIONS.

Which Foods are Recommended for Mucinous Ovarian Cancer?

Eat more fruits, Quince or Pummelo?

Fruits are an important part of many diets. The active ingredients contained in Quince are Modified Citrus Pectin, Oleic Acid, Vitamin C, Quercitrin, Chlorogenic Acid among others. While the active ingredients contained in Pummelo are Naringin, Beta-sitosterol, Vitamin C, Oleic Acid, Linolenic Acid and others.

Quercitrin can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Modified Citrus Pectin has biological action on biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling.

Naringetol can manipulate biochemical pathways WNT Beta Catenin Signaling. Hesperetin has biological action on biochemical pathways WNT Beta Catenin Signaling. And so on.

When treating Mucinous Ovarian Cancer with chemotherapy Nivolumab – Foods like Quince are recommended compared to Pummelo. This is because the active ingredients Naringetol and Hesperetin in Pummelo interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Quercitrin and Modified Citrus Pectin contained in Quince support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: QUINCE IS RECOMMENDED OVER PUMMELO FOR MUCINOUS OVARIAN CANCER ON TREATMENT WITH CHEMOTHERAPY NIVOLUMAB FOR SOME CONDITIONS.

Eat more nuts, Hazelnut or Cashew Nut?

Nuts are an important part of many diets. The active ingredients contained in Hazelnut are Vitamin E, Oleic Acid, Linolenic Acid, Quercetin, Linoleic Acid among others. While the active ingredients contained in Cashew Nut are Beta-sitosterol, Vitamin C, Butyric Acid, Gallic Acid, Palmitic Acid and others.

Vitamin E can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Quercetin has biological action on biochemical pathways WNT Beta Catenin Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling.

Palmitic Acid can manipulate biochemical pathways WNT Beta Catenin Signaling. Lauric Acid has biological action on biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. And so on.

When treating Mucinous Ovarian Cancer with chemotherapy Nivolumab – Foods like Hazelnut are recommended compared to Cashew Nut. This is because the active ingredients Palmitic Acid and Lauric Acid in Cashew Nut interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Vitamin E and Quercetin contained in Hazelnut support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: HAZELNUT IS RECOMMENDED OVER CASHEW NUT FOR MUCINOUS OVARIAN CANCER ON TREATMENT WITH CHEMOTHERAPY NIVOLUMAB FOR SOME CONDITIONS.

Foods for Genetic Risk of Mucinous Ovarian Cancer

One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. SMAD4 and CDKN2A are two genes whose abnormalities are risk factors for Mucinous Ovarian Cancer. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Mucinous Ovarian Cancer can be used as a guide for coming up with a recommended personalized nutrition plan. For Mucinous Ovarian Cancer gene SMAD4 has causative impact on biological pathways like TGFB Signaling, Inflammation and Cell Cycle. And CDKN2A has a causative impact on biological pathways like Cell Cycle Checkpoints and Cell Cycle. Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like SMAD4 and CDKN2A should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes SMAD4 and CDKN2A should be avoided.

Eat more pulses, Lentils or Fava Bean?

The active ingredients contained in Lentils are Esculin, Ellagic Acid, Daidzein, Beta-sitosterol, Linolenic Acid among others. While the active ingredients contained in Fava Bean are Daidzein, Quercetin, Beta-sitosterol, Cianidanol, Ferulic Acid and others.

Esculin can manipulate biochemical pathways MAPK Signaling, Cell Cycle Checkpoints and P53 Signaling. Ellagic Acid has biological action on biochemical pathways RAS-RAF Signaling, PI3K-AKT-MTOR Signaling and Apoptosis.

Folic Acid can manipulate biochemical pathways MAPK Signaling, Cell Cycle Checkpoints and RAS-RAF Signaling. And so on.

For genetic risk of Mucinous Ovarian Cancer due to abnormalities in genes SMAD4 and CDKN2A – Foods like Lentils are recommended compared to Fava Bean. This is because the active ingredients Folic Acid in Fava Bean further promote the effects of genes on the biochemical pathways. While the active ingredients Esculin and Ellagic Acid contained in Lentils together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: LENTILS IS RECOMMENDED OVER FAVA BEAN FOR REDUCING THE GENETIC RISK OF MUCINOUS OVARIAN CANCER DUE TO GENES SMAD4 AND CDKN2A

Eat more vegetables, Cassava or Carob?

The active ingredients contained in Cassava are Beta-sitosterol, Linolenic Acid, Vitamin C, Oleic Acid, Linoleic Acid among others. While the active ingredients contained in Carob are Quercetin, Palmitic Acid, Myricetin, Gallic Acid, Phloroglucinol and others.

Vitamin C can manipulate biochemical pathways MAPK Signaling, Cell Cycle Checkpoints and RAS-RAF Signaling. Beta-sitosterol has biological action on biochemical pathways P53 Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling.

Palmitic Acid can manipulate biochemical pathways MAPK Signaling. Folic Acid has biological action on biochemical pathways Cell Cycle Checkpoints, RAS-RAF Signaling and P53 Signaling. And so on.

For genetic risk of Mucinous Ovarian Cancer due to abnormalities in genes SMAD4 and CDKN2A – Foods like Cassava are recommended compared to Carob. This is because the active ingredients Palmitic Acid and Folic Acid in Carob further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Cassava together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: CASSAVA IS RECOMMENDED OVER CAROB FOR REDUCING THE GENETIC RISK OF MUCINOUS OVARIAN CANCER DUE TO GENES SMAD4 AND CDKN2A

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Eat more fruits, Graviola or Raspberry?

The active ingredients contained in Graviola are Emodin, Vitamin E, Lycopene, Daidzein, Quercetin among others. While the active ingredients contained in Raspberry are Ellagic Acid, Quercetin, Resveratrol, Vitamin C, Salicylic Acid and others.

Emodin can manipulate biochemical pathways Cell Cycle Checkpoints, P53 Signaling and MYC Signaling. Fisetin has biological action on biochemical pathways MAPK Signaling, Cell Cycle and PI3K-AKT-MTOR Signaling.

Resveratrol can manipulate biochemical pathways P53 Signaling. And so on.

For genetic risk of Mucinous Ovarian Cancer due to abnormalities in genes SMAD4 and CDKN2A – Foods like Graviola are recommended compared to Raspberry. This is because the active ingredients Resveratrol in Raspberry further promote the effects of genes on the biochemical pathways. While the active ingredients Emodin and Fisetin contained in Graviola together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: GRAVIOLA IS RECOMMENDED OVER RASPBERRY FOR REDUCING THE GENETIC RISK OF MUCINOUS OVARIAN CANCER DUE TO GENES SMAD4 AND CDKN2A

Eat more nuts, Almond or Chestnut?

The active ingredients contained in Almond are Vitamin E, Quercetin, Beta-sitosterol, Linolenic Acid, Oleic Acid among others. While the active ingredients contained in Chestnut are Ellagic Acid, Quercetin, Linolenic Acid, Vitamin C, Oleic Acid and others.

Beta-sitosterol can manipulate biochemical pathways Cell Cycle Checkpoints, P53 Signaling and MYC Signaling. Vitamin E has biological action on biochemical pathways MAPK Signaling, PI3K-AKT-MTOR Signaling and Apoptosis.

Folic Acid can manipulate biochemical pathways MAPK Signaling, Cell Cycle Checkpoints and RAS-RAF Signaling. And so on.

For genetic risk of Mucinous Ovarian Cancer due to abnormalities in genes SMAD4 and CDKN2A – Foods like Almond are recommended compared to Chestnut. This is because the active ingredients Folic Acid in Chestnut further promote the effects of genes on the biochemical pathways. While the active ingredients Beta-sitosterol and Vitamin E contained in Almond together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: ALMOND IS RECOMMENDED OVER CHESTNUT FOR REDUCING THE GENETIC RISK OF MUCINOUS OVARIAN CANCER DUE TO GENES SMAD4 AND CDKN2A


In Summary

An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.

“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.

You can get started NOW and design a personalized nutrition plan for Mucinous Ovarian Cancer by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

sample-report


References

Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

You can also read this in

How useful was this post?

Click on a star to rate it!

Average rating 4.7 / 5. Vote count: 26

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?