Which Foods are Recommended for Goblet Cell Carcinoid Of The Appendix?

Highlights

No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Goblet Cell Carcinoid Of The Appendix when undergoing chemotherapy or when you determine you have a genetic risk for developing Goblet Cell Carcinoid Of The Appendix because of ALK and APC gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.

There is no one answer to this question for cancers such as Goblet Cell Carcinoid Of The Appendix which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.

In short – the process to answer questions like “Should I Avoid eating fruit Strawberry” or “Include fruit Gooseberry in my diet” or “Should I reduce consumption of vegetable Japanese Pumpkin” or “Can I take Modified Citrus Pectin and Ashitaba supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.

RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO GOBLET CELL CARCINOID OF THE APPENDIX, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.

The overall objective of personalized nutrition for Goblet Cell Carcinoid Of The Appendix is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.

RECOMMENDATION: UPDATE YOUR NUTRITION FOR GOBLET CELL CARCINOID OF THE APPENDIX, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.

About Goblet Cell Carcinoid Of The Appendix

cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.

Following key highlights are derived from clinical data for Goblet Cell Carcinoid Of The Appendix from cBioPortal. 42.9% of males and 57.1% of females were the distribution of gender in these clinical studies. From a patient sample size of 7; the top genes with mutations and other abnormalities for Goblet Cell Carcinoid Of The Appendix include genes ALK, APC, ARID1A, INHBA and KDM6A. The occurrence frequency distribution for these genes respectively is 33.3%, 33.3%, 33.3%, 33.3% and 33.3%. These tumor genetic details of Goblet Cell Carcinoid Of The Appendix are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Goblet Cell Carcinoid Of The Appendix.

Significance of Nutrition for Goblet Cell Carcinoid Of The Appendix

All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Goblet Cell Carcinoid Of The Appendix. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.

For example Strawberry includes active ingredients Ellagic Acid, Lupeol, Linolenic Acid, Oleic Acid, Vitamin C and others. And Gooseberry contains active ingredients Modified Citrus Pectin, Vitamin C, Oleic Acid, Linolenic Acid, Beta-sitosterol and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.

For cancers like Goblet Cell Carcinoid Of The Appendix, activation or inhibition of selected biochemical pathways like MAPK Signaling, PI3K-AKT-MTOR Signaling, Growth Factor Signaling, Chromatin Remodeling plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Goblet Cell Carcinoid Of The Appendix, while eating some other foods and supplements may not be recommended.

One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR GOBLET CELL CARCINOID OF THE APPENDIX – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.

Foods for Goblet Cell Carcinoid Of The Appendix undergoing chemotherapy treatment

In Goblet Cell Carcinoid Of The Appendix – the genes ALK, APC, ARID1A, INHBA and KDM6A have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Goblet Cell Carcinoid Of The Appendix are MAPK Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling and others. Pazopanib is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers MAPK Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.

RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.

Eat more pulses, Winged Bean or Moth Bean?

Pulses are an important part of many diets. The active ingredients contained in Winged Bean are Betulinic Acid, Vitamin C, Oleic Acid, Linolenic Acid, Linoleic Acid among others. While the active ingredients contained in Moth Bean are Linolenic Acid, Oleic Acid, Stigmasterol, Beta-sitosterol, Linoleic Acid and others.

Betulinic Acid can manipulate biochemical pathways MAPK Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling. Vitamin C has biological action on biochemical pathways RAS-RAF Signaling, MAPK Signaling and MYC Signaling.

Folic Acid can manipulate biochemical pathways MAPK Signaling, MYC Signaling and RAS-RAF Signaling. And so on.

When treating Goblet Cell Carcinoid Of The Appendix with chemotherapy Pazopanib – Foods like Winged Bean are recommended compared to Moth Bean. This is because the active ingredients Folic Acid in Moth Bean interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Betulinic Acid and Vitamin C contained in Winged Bean support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: WINGED BEAN IS RECOMMENDED OVER MOTH BEAN FOR GOBLET CELL CARCINOID OF THE APPENDIX ON TREATMENT WITH CHEMOTHERAPY PAZOPANIB FOR SOME CONDITIONS.

Eat more vegetables, Tomato or Japanese Pumpkin?

Vegetables are an important part of many diets. The active ingredients contained in Tomato are Lycopene, Glucaric Acid, Lupeol, Vitamin C, Oleic Acid among others. While the active ingredients contained in Japanese Pumpkin are Vitamin E, Vitamin C, Beta-sitosterol, Vitamin A, Palmitic Acid and others.

Lycopene can manipulate biochemical pathways MAPK Signaling, MYC Signaling and RAS-RAF Signaling. Glucaric Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MAPK Signaling and MYC Signaling.

Palmitic Acid can manipulate biochemical pathways MAPK Signaling. Lauric Acid has biological action on biochemical pathways MYC Signaling, PI3K-AKT-MTOR Signaling and MAPK Signaling. And so on.

When treating Goblet Cell Carcinoid Of The Appendix with chemotherapy Pazopanib – Foods like Tomato are recommended compared to Japanese Pumpkin. This is because the active ingredients Palmitic Acid and Lauric Acid in Japanese Pumpkin interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Lycopene and Glucaric Acid contained in Tomato support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: TOMATO IS RECOMMENDED OVER JAPANESE PUMPKIN FOR GOBLET CELL CARCINOID OF THE APPENDIX ON TREATMENT WITH CHEMOTHERAPY PAZOPANIB FOR SOME CONDITIONS.

Eat more fruits, Gooseberry or Strawberry?

Fruits are an important part of many diets. The active ingredients contained in Gooseberry are Modified Citrus Pectin, Vitamin C, Oleic Acid, Linolenic Acid, Beta-sitosterol among others. While the active ingredients contained in Strawberry are Ellagic Acid, Lupeol, Linolenic Acid, Oleic Acid, Vitamin C and others.

Vitamin C can manipulate biochemical pathways MAPK Signaling, MYC Signaling and RAS-RAF Signaling. Gallic Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MAPK Signaling and MYC Signaling.

Fisetin can manipulate biochemical pathways MYC Signaling. Ellagic Acid has biological action on biochemical pathways MYC Signaling. And so on.

When treating Goblet Cell Carcinoid Of The Appendix with chemotherapy Pazopanib – Foods like Gooseberry are recommended compared to Strawberry. This is because the active ingredients Fisetin and Ellagic Acid in Strawberry interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Vitamin C and Gallic Acid contained in Gooseberry support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: GOOSEBERRY IS RECOMMENDED OVER STRAWBERRY FOR GOBLET CELL CARCINOID OF THE APPENDIX ON TREATMENT WITH CHEMOTHERAPY PAZOPANIB FOR SOME CONDITIONS.

Eat more nuts, Pistachio or Macadamia Nut?

Nuts are an important part of many diets. The active ingredients contained in Pistachio are Vitamin E, Resveratrol, Linolenic Acid, Oleic Acid, Stigmasterol among others. While the active ingredients contained in Macadamia Nut are Beta-sitosterol, Palmitic Acid, Lauric Acid, Myristic Acid, Folic Acid and others.

Beta-sitosterol can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Vitamin E has biological action on biochemical pathways MAPK Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling.

Palmitic Acid can manipulate biochemical pathways MAPK Signaling. Lauric Acid has biological action on biochemical pathways MYC Signaling, PI3K-AKT-MTOR Signaling and MAPK Signaling. And so on.

When treating Goblet Cell Carcinoid Of The Appendix with chemotherapy Pazopanib – Foods like Pistachio are recommended compared to Macadamia Nut. This is because the active ingredients Palmitic Acid and Lauric Acid in Macadamia Nut interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Beta-sitosterol and Vitamin E contained in Pistachio support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: PISTACHIO IS RECOMMENDED OVER MACADAMIA NUT FOR GOBLET CELL CARCINOID OF THE APPENDIX ON TREATMENT WITH CHEMOTHERAPY PAZOPANIB FOR SOME CONDITIONS.

Foods for Genetic Risk of Goblet Cell Carcinoid Of The Appendix

One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. ALK and APC are two genes whose abnormalities are risk factors for Goblet Cell Carcinoid Of The Appendix. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Goblet Cell Carcinoid Of The Appendix can be used as a guide for coming up with a recommended personalized nutrition plan. For Goblet Cell Carcinoid Of The Appendix gene ALK has causative impact on biological pathways like Growth Factor Signaling, JAK-STAT Signaling and Immune Checkpoints. And APC has a causative impact on biological pathways like Angiogenesis and Growth Factor Signaling. Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like ALK and APC should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes ALK and APC should be avoided.

Eat more pulses, Mung Bean or Hyacinth Bean?

The active ingredients contained in Mung Bean are Quercetin, Kaempferol, Oleic Acid, Linolenic Acid, Stigmasterol among others. While the active ingredients contained in Hyacinth Bean are Vitamin C, Genistein, Palmitic Acid, Myristic Acid, Folic Acid and others.

Quercetin can manipulate biochemical pathways MAPK Signaling, RAS-RAF Signaling and JAK-STAT Signaling. Kaempferol has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MAPK Signaling and JAK-STAT Signaling.

Palmitic Acid can manipulate biochemical pathways MAPK Signaling, MYC Signaling and DNA Repair. Myristic Acid has biological action on biochemical pathways P53 Signaling, RAS-RAF Signaling and MAPK Signaling. And so on.

For genetic risk of Goblet Cell Carcinoid Of The Appendix due to abnormalities in genes ALK and APC – Foods like Mung Bean are recommended compared to Hyacinth Bean. This is because the active ingredients Palmitic Acid and Myristic Acid in Hyacinth Bean further promote the effects of genes on the biochemical pathways. While the active ingredients Quercetin and Kaempferol contained in Mung Bean together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: MUNG BEAN IS RECOMMENDED OVER HYACINTH BEAN FOR REDUCING THE GENETIC RISK OF GOBLET CELL CARCINOID OF THE APPENDIX DUE TO GENES ALK AND APC

Eat more vegetables, Brussels Sprout or Radish?

The active ingredients contained in Brussels Sprout are Brassinin, Oleic Acid, Linolenic Acid, Vitamin C, Sulforaphane among others. While the active ingredients contained in Radish are Quercetin, Caffeic Acid, Kaempferol, Oleic Acid, Linolenic Acid and others.

Brassinin can manipulate biochemical pathways MAPK Signaling, JAK-STAT Signaling and P53 Signaling. Vitamin C has biological action on biochemical pathways RAS-RAF Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling.

Pelargonidin can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Vitamin B3 has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.

For genetic risk of Goblet Cell Carcinoid Of The Appendix due to abnormalities in genes ALK and APC – Foods like Brussels Sprout are recommended compared to Radish. This is because the active ingredients Pelargonidin and Vitamin B3 in Radish further promote the effects of genes on the biochemical pathways. While the active ingredients Brassinin and Vitamin C contained in Brussels Sprout together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: BRUSSELS SPROUT IS RECOMMENDED OVER RADISH FOR REDUCING THE GENETIC RISK OF GOBLET CELL CARCINOID OF THE APPENDIX DUE TO GENES ALK AND APC

Eat more fruits, Orange or Huckleberry?

The active ingredients contained in Orange are D-limonene, Modified Citrus Pectin, Linalool, Oleic Acid, Linolenic Acid among others. While the active ingredients contained in Huckleberry are Quercetin, Resveratrol, Caffeic Acid, Delphinidin, Vitamin C and others.

D-limonene can manipulate biochemical pathways MAPK Signaling, RAS-RAF Signaling and P53 Signaling. Vitamin C has biological action on biochemical pathways MYC Signaling, PI3K-AKT-MTOR Signaling and MAPK Signaling.

Resveratrol can manipulate biochemical pathways P53 Signaling. Ferulic Acid has biological action on biochemical pathways DNA Repair. And so on.

For genetic risk of Goblet Cell Carcinoid Of The Appendix due to abnormalities in genes ALK and APC – Foods like Orange are recommended compared to Huckleberry. This is because the active ingredients Resveratrol and Ferulic Acid in Huckleberry further promote the effects of genes on the biochemical pathways. While the active ingredients D-limonene and Vitamin C contained in Orange together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: ORANGE IS RECOMMENDED OVER HUCKLEBERRY FOR REDUCING THE GENETIC RISK OF GOBLET CELL CARCINOID OF THE APPENDIX DUE TO GENES ALK AND APC

Eat more nuts, Almond or Brazil Nut?

The active ingredients contained in Almond are Quercetin, Oleic Acid, Linolenic Acid, Vitamin E, Stigmasterol among others. While the active ingredients contained in Brazil Nut are Oleic Acid, Linolenic Acid, Vitamin E, Lecithin, Folic Acid and others.

Beta-sitosterol can manipulate biochemical pathways P53 Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling. Quercetin has biological action on biochemical pathways MAPK Signaling, RAS-RAF Signaling and JAK-STAT Signaling.

Lecithin can manipulate biochemical pathways MAPK Signaling, MYC Signaling and JAK-STAT Signaling. Folic Acid has biological action on biochemical pathways RAS-RAF Signaling, P53 Signaling and PI3K-AKT-MTOR Signaling. And so on.

For genetic risk of Goblet Cell Carcinoid Of The Appendix due to abnormalities in genes ALK and APC – Foods like Almond are recommended compared to Brazil Nut. This is because the active ingredients Lecithin and Folic Acid in Brazil Nut further promote the effects of genes on the biochemical pathways. While the active ingredients Beta-sitosterol and Quercetin contained in Almond together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: ALMOND IS RECOMMENDED OVER BRAZIL NUT FOR REDUCING THE GENETIC RISK OF GOBLET CELL CARCINOID OF THE APPENDIX DUE TO GENES ALK AND APC

In Summary

An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.

“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.

You can get started NOW and design a personalized nutrition plan for Goblet Cell Carcinoid Of The Appendix by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

References

• Msk Impact 2017
• Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.
• Cryptorchidism: a pediatrician’s view.
• Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
• Sequential protooncogene expression in regenerating kidney following acute renal injury.
• Gallic acid indanone and mangiferin xanthone are strong determinants of immunosuppressive anti-tumour effects of Mangifera indica L. bark in MDA-MB231 breast cancer cells.
• Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin.
• Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application.
• Lycopene differentially induces quiescence and apoptosis in androgen-responsive and -independent prostate cancer cell lines.
• Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs.
• Functional lipidomics: Palmitic acid impairs hepatocellular carcinoma development by modulating membrane fluidity and glucose metabolism.
• Clinical pharmacodynamics of antihistamines.
• Paederia foetida induces anticancer activity by modulating chromatin modification enzymes and altering pro-inflammatory cytokine gene expression in human prostate cancer cells.
• Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling.
• Protein kinase and HDAC inhibitors from the endophytic fungus Epicoccum nigrum.
• Flavonoids as receptor tyrosine kinase FLT3 inhibitors.
• Sequence homology of surface membrane proteins of Babesia rodhaini.
• D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis.
• Resveratrol, a remarkable inhibitor of ribonucleotide reductase.
• Legionella pneumophila serogroup 12 pneumonia in a renal transplant recipient: case report and environmental observations.
• Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel.
• Pelargonidin reduces the TPA induced transformation of mouse epidermal cells -potential involvement of Nrf2 promoter demethylation.
• Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes.
• The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras.
• HyperFoods: Machine intelligent mapping of cancer-beating molecules in foods.
• Fisetin: a dietary antioxidant for health promotion.