Which Foods are Recommended for Mucosal Melanoma Of The Esophagus?

Highlights

No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Mucosal Melanoma Of The Esophagus when undergoing chemotherapy or when you determine you have a genetic risk for developing Mucosal Melanoma Of The Esophagus because of AXL and BRCA2 gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.

There is no one answer to this question for cancers such as Mucosal Melanoma Of The Esophagus which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.

In short – the process to answer questions like “Should I Avoid eating fruit Strawberry” or “Include fruit Partridgeberry in my diet” or “Should I reduce consumption of vegetable Radish” or “Can I take Stevia and Lavender supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.

RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO MUCOSAL MELANOMA OF THE ESOPHAGUS, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.

The overall objective of personalized nutrition for Mucosal Melanoma Of The Esophagus is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.

RECOMMENDATION: UPDATE YOUR NUTRITION FOR MUCOSAL MELANOMA OF THE ESOPHAGUS, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.

About Mucosal Melanoma Of The Esophagus

cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.

Following key highlights are derived from clinical data for Mucosal Melanoma Of The Esophagus from cBioPortal. 55.6% of males and 44.4% of females were the distribution of gender in these clinical studies. From a patient sample size of 10; the top genes with mutations and other abnormalities for Mucosal Melanoma Of The Esophagus include genes PIK3CA, AXL, BRCA2, DNMT3A and EPHA3. The occurrence frequency distribution for these genes respectively is 20.0%, 10.0%, 10.0%, 10.0% and 10.0%. These tumor genetic details of Mucosal Melanoma Of The Esophagus are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Mucosal Melanoma Of The Esophagus.

Significance of Nutrition for Mucosal Melanoma Of The Esophagus

All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Mucosal Melanoma Of The Esophagus. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.

For example Strawberry includes active ingredients Ellagic Acid, Lupeol, Vitamin C, Oleic Acid, Salicylic Acid and others. And Partridgeberry contains active ingredients Resveratrol, Beta-sitosterol, Stigmasterol and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.

For cancers like Mucosal Melanoma Of The Esophagus, activation or inhibition of selected biochemical pathways like RAS-RAF Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling, Growth Factor Signaling plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Mucosal Melanoma Of The Esophagus, while eating some other foods and supplements may not be recommended.

One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR MUCOSAL MELANOMA OF THE ESOPHAGUS – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.

Foods for Mucosal Melanoma Of The Esophagus undergoing chemotherapy treatment

In Mucosal Melanoma Of The Esophagus – the genes PIK3CA, AXL, BRCA2, DNMT3A and EPHA3 have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Mucosal Melanoma Of The Esophagus are RAS-RAF Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling and others. Cytarabine is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers RAS-RAF Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.

RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.

Eat more pulses, Mung Bean or Soy Bean?

Pulses are an important part of many diets. The active ingredients contained in Mung Bean are Glucaric Acid, Quercetin, Vitamin C, Oleic Acid, Vitexin among others. While the active ingredients contained in Soy Bean are Lupeol, Quercetin, Daidzein, Vitamin C, Vitamin E and others.

Glucaric Acid can manipulate biochemical pathways MYC Signaling, RAS-RAF Signaling and MAPK Signaling. Quercetin has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MYC Signaling and RAS-RAF Signaling.

Lecithin can manipulate biochemical pathways MYC Signaling, MAPK Signaling and PI3K-AKT-MTOR Signaling. Fisetin has biological action on biochemical pathways MYC Signaling. And so on.

When treating Mucosal Melanoma Of The Esophagus with chemotherapy Cytarabine – Foods like Mung Bean are recommended compared to Soy Bean. This is because the active ingredients Lecithin and Fisetin in Soy Bean interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Glucaric Acid and Quercetin contained in Mung Bean support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: MUNG BEAN IS RECOMMENDED OVER SOY BEAN FOR MUCOSAL MELANOMA OF THE ESOPHAGUS ON TREATMENT WITH CHEMOTHERAPY CYTARABINE FOR SOME CONDITIONS.

Eat more vegetables, Tomato or Radish?

Vegetables are an important part of many diets. The active ingredients contained in Tomato are Lycopene, Glucaric Acid, Lupeol, Vitamin C, Isoquercitrin among others. While the active ingredients contained in Radish are Isorhamnetin, Quercetin, Vitamin C, Oleic Acid, Salicylic Acid and others.

Lycopene can manipulate biochemical pathways MYC Signaling, RAS-RAF Signaling and MAPK Signaling. Glucaric Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MYC Signaling and RAS-RAF Signaling.

Pelargonidin can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Folic Acid has biological action on biochemical pathways RAS-RAF Signaling, MAPK Signaling and MYC Signaling. And so on.

When treating Mucosal Melanoma Of The Esophagus with chemotherapy Cytarabine – Foods like Tomato are recommended compared to Radish. This is because the active ingredients Pelargonidin and Folic Acid in Radish interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Lycopene and Glucaric Acid contained in Tomato support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: TOMATO IS RECOMMENDED OVER RADISH FOR MUCOSAL MELANOMA OF THE ESOPHAGUS ON TREATMENT WITH CHEMOTHERAPY CYTARABINE FOR SOME CONDITIONS.

Eat more fruits, Partridgeberry or Strawberry?

Fruits are an important part of many diets. The active ingredients contained in Partridgeberry are Resveratrol, Beta-sitosterol, Stigmasterol among others. While the active ingredients contained in Strawberry are Ellagic Acid, Lupeol, Vitamin C, Oleic Acid, Salicylic Acid and others.

Resveratrol can manipulate biochemical pathways MYC Signaling, RAS-RAF Signaling and PI3K-AKT-MTOR Signaling. Beta-sitosterol has biological action on biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling.

Fisetin can manipulate biochemical pathways MYC Signaling. Ellagic Acid has biological action on biochemical pathways MYC Signaling. And so on.

When treating Mucosal Melanoma Of The Esophagus with chemotherapy Cytarabine – Foods like Partridgeberry are recommended compared to Strawberry. This is because the active ingredients Fisetin and Ellagic Acid in Strawberry interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Resveratrol and Beta-sitosterol contained in Partridgeberry support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: PARTRIDGEBERRY IS RECOMMENDED OVER STRAWBERRY FOR MUCOSAL MELANOMA OF THE ESOPHAGUS ON TREATMENT WITH CHEMOTHERAPY CYTARABINE FOR SOME CONDITIONS.

Eat more nuts, Pine Nut or Peanut?

Nuts are an important part of many diets. The active ingredients contained in Pine Nut are Vitamin E, Oleic Acid, Beta-sitosterol, Linolenic Acid, Linoleic Acid among others. While the active ingredients contained in Peanut are Quercetin, Vitamin E, Vitamin C, Oleic Acid, Beta-sitosterol and others.

Beta-sitosterol can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Vitamin K has biological action on biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling.

Lecithin can manipulate biochemical pathways MYC Signaling, MAPK Signaling and PI3K-AKT-MTOR Signaling. Folic Acid has biological action on biochemical pathways RAS-RAF Signaling, MYC Signaling and MAPK Signaling. And so on.

When treating Mucosal Melanoma Of The Esophagus with chemotherapy Cytarabine – Foods like Pine Nut are recommended compared to Peanut. This is because the active ingredients Lecithin and Folic Acid in Peanut interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Beta-sitosterol and Vitamin K contained in Pine Nut support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: PINE NUT IS RECOMMENDED OVER PEANUT FOR MUCOSAL MELANOMA OF THE ESOPHAGUS ON TREATMENT WITH CHEMOTHERAPY CYTARABINE FOR SOME CONDITIONS.

Foods for Genetic Risk of Mucosal Melanoma Of The Esophagus

One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. AXL and BRCA2 are two genes whose abnormalities are risk factors for Mucosal Melanoma Of The Esophagus. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Mucosal Melanoma Of The Esophagus can be used as a guide for coming up with a recommended personalized nutrition plan. For Mucosal Melanoma Of The Esophagus gene AXL has causative impact on biological pathways like . And BRCA2 has a causative impact on biological pathways like DNA Repair and DNA Repair. Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like AXL and BRCA2 should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes AXL and BRCA2 should be avoided.

Eat more pulses, Scarlet Bean or Moth Bean?

The active ingredients contained in Scarlet Bean are Oleic Acid, Linolenic Acid, Vitamin C, Beta-sitosterol, Stigmasterol among others. While the active ingredients contained in Moth Bean are Oleic Acid, Linolenic Acid, Beta-sitosterol, Stigmasterol, Linoleic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, Growth Factor Signaling and MYC Signaling. Beta-sitosterol has biological action on biochemical pathways P53 Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling.

Vitamin A can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Linoleic Acid has biological action on biochemical pathways Growth Factor Signaling. And so on.

For genetic risk of Mucosal Melanoma Of The Esophagus due to abnormalities in genes AXL and BRCA2 – Foods like Scarlet Bean are recommended compared to Moth Bean. This is because the active ingredients Vitamin A and Linoleic Acid in Moth Bean further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Scarlet Bean together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: SCARLET BEAN IS RECOMMENDED OVER MOTH BEAN FOR REDUCING THE GENETIC RISK OF MUCOSAL MELANOMA OF THE ESOPHAGUS DUE TO GENES AXL AND BRCA2

Eat more vegetables, Cassava or Chicory?

The active ingredients contained in Cassava are Oleic Acid, Linolenic Acid, Vitamin C, Beta-sitosterol, Linoleic Acid among others. While the active ingredients contained in Chicory are Apigenin, Esculin, Quercetin, Lupeol, Betulinic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, Growth Factor Signaling and MYC Signaling. Beta-sitosterol has biological action on biochemical pathways P53 Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling.

Vitamin A can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Gallic Acid has biological action on biochemical pathways DNA Repair. And so on.

For genetic risk of Mucosal Melanoma Of The Esophagus due to abnormalities in genes AXL and BRCA2 – Foods like Cassava are recommended compared to Chicory. This is because the active ingredients Vitamin A and Gallic Acid in Chicory further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Cassava together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: CASSAVA IS RECOMMENDED OVER CHICORY FOR REDUCING THE GENETIC RISK OF MUCOSAL MELANOMA OF THE ESOPHAGUS DUE TO GENES AXL AND BRCA2

Eat more fruits, Feijoa or Date?

The active ingredients contained in Feijoa are Lycopene, Vitamin C, Casuarinin, Folic Acid among others. While the active ingredients contained in Date are Apigenin, Quercetin, Lupeol, Oleic Acid, Linolenic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, Growth Factor Signaling and MYC Signaling. Lycopene has biological action on biochemical pathways P53 Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling.

Ferulic Acid can manipulate biochemical pathways DNA Repair and Growth Factor Signaling. Gallic Acid has biological action on biochemical pathways DNA Repair. And so on.

For genetic risk of Mucosal Melanoma Of The Esophagus due to abnormalities in genes AXL and BRCA2 – Foods like Feijoa are recommended compared to Date. This is because the active ingredients Ferulic Acid and Gallic Acid in Date further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Lycopene contained in Feijoa together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: FEIJOA IS RECOMMENDED OVER DATE FOR REDUCING THE GENETIC RISK OF MUCOSAL MELANOMA OF THE ESOPHAGUS DUE TO GENES AXL AND BRCA2

Eat more nuts, Hazelnut or Acorn?

The active ingredients contained in Hazelnut are Quercetin, Vitamin E, Oleic Acid, Linolenic Acid, Linoleic Acid among others. While the active ingredients contained in Acorn are Quercetin, Vitamin C, Beta-sitosterol, Vitamin B3, Quercitrin and others.

Quercetin can manipulate biochemical pathways Apoptosis, Growth Factor Signaling and EPHRIN Signaling. Vitamin E has biological action on biochemical pathways MYC Signaling, P53 Signaling and Cell Cycle Checkpoints.

Beta-carotene can manipulate biochemical pathways DNA Repair and PI3K-AKT-MTOR Signaling. Gallic Acid has biological action on biochemical pathways DNA Repair. And so on.

For genetic risk of Mucosal Melanoma Of The Esophagus due to abnormalities in genes AXL and BRCA2 – Foods like Hazelnut are recommended compared to Acorn. This is because the active ingredients Beta-carotene and Gallic Acid in Acorn further promote the effects of genes on the biochemical pathways. While the active ingredients Quercetin and Vitamin E contained in Hazelnut together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: HAZELNUT IS RECOMMENDED OVER ACORN FOR REDUCING THE GENETIC RISK OF MUCOSAL MELANOMA OF THE ESOPHAGUS DUE TO GENES AXL AND BRCA2

In Summary

An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.

“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.

You can get started NOW and design a personalized nutrition plan for Mucosal Melanoma Of The Esophagus by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

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