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What Foods are Recommended for Cancer?
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.

Which Foods are Recommended for Hemangioblastoma?

Aug 24, 2022

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Highlights

No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Hemangioblastoma when undergoing chemotherapy or when you determine you have a genetic risk for developing Hemangioblastoma because of VHL and XPC gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.

There is no one answer to this question for cancers such as Hemangioblastoma which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.

In short – the process to answer questions like “Should I Avoid eating fruit Quince” or “Include fruit Saskatoon Berry in my diet” or “Should I reduce consumption of vegetable Beetroot” or “Can I take Mulberry and Quercetin supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.

RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO HEMANGIOBLASTOMA, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.

The overall objective of personalized nutrition for Hemangioblastoma is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.

RECOMMENDATION: UPDATE YOUR NUTRITION FOR HEMANGIOBLASTOMA, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.



About Hemangioblastoma

cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.

Following key highlights are derived from clinical data for Hemangioblastoma from cBioPortal. 66.7% of males and 33.3% of females were the distribution of gender in these clinical studies. From a patient sample size of 3; the top genes with mutations and other abnormalities for Hemangioblastoma include genes VHL, XPC, FUS, KDM6B and TP53BP1. The occurrence frequency distribution for these genes respectively is 58.6%, 18.2%, 11.1%, 11.1% and 10.0%. These tumor genetic details of Hemangioblastoma are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Hemangioblastoma.

Significance of Nutrition for Hemangioblastoma

All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Hemangioblastoma. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.

For example Quince includes active ingredients Vitamin C, Oleic Acid, Chlorogenic Acid, Modified Citrus Pectin, Quercitrin and others. And Saskatoon Berry contains active ingredients Quercetin, Delphinidin and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.

For cancers like Hemangioblastoma, activation or inhibition of selected biochemical pathways like Angiogenesis, MAPK Signaling, Hypoxia, DNA Repair plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Hemangioblastoma, while eating some other foods and supplements may not be recommended.

One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

For cancers like Hemangioblastoma, activation or inhibition of selected biochemical pathways like Angiogenesis, MAPK Signaling, Hypoxia, DNA Repair plays an important role in driving cancer growth.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR HEMANGIOBLASTOMA – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.

Foods for Hemangioblastoma undergoing chemotherapy treatment

In Hemangioblastoma – the genes VHL, XPC, FUS, KDM6B and TP53BP1 have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Hemangioblastoma are Angiogenesis, MAPK Signaling, Hypoxia and others. Bevacizumab is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers Angiogenesis, MAPK Signaling, Hypoxia so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.

RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.

Eat more pulses, Mung Bean or Lentils?

Pulses are an important part of many diets. The active ingredients contained in Mung Bean are Quercetin, Vitamin C, Oleic Acid, Kaempferol, Linolenic Acid among others. While the active ingredients contained in Lentils are Ellagic Acid, Daidzein, Isoliquiritigenin, Vitamin C, Oleic Acid and others.

Quercetin can manipulate biochemical pathways Angiogenesis, MAPK Signaling and MYC Signaling. Vitamin C has biological action on biochemical pathways Hypoxia, PI3K-AKT-MTOR Signaling and MAPK Signaling.

Ellagic Acid can manipulate biochemical pathways MYC Signaling. Esculin has biological action on biochemical pathways TGFB Signaling. And so on.

When treating Hemangioblastoma with chemotherapy Bevacizumab – Foods like Mung Bean are recommended compared to Lentils. This is because the active ingredients Ellagic Acid and Esculin in Lentils interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Quercetin and Vitamin C contained in Mung Bean support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: MUNG BEAN IS RECOMMENDED OVER LENTILS FOR HEMANGIOBLASTOMA ON TREATMENT WITH CHEMOTHERAPY BEVACIZUMAB FOR SOME CONDITIONS.

Eat more vegetables, Asparagus or Beetroot?

Vegetables are an important part of many diets. The active ingredients contained in Asparagus are Quercetin, Vitamin C, Oleic Acid, Isorhamnetin, Kaempferol among others. While the active ingredients contained in Beetroot are Vitamin C, Oleic Acid, Beta-sitosterol, Vitamin E, Linolenic Acid and others.

Quercetin can manipulate biochemical pathways Angiogenesis, MAPK Signaling and MYC Signaling. Vitamin C has biological action on biochemical pathways Hypoxia, PI3K-AKT-MTOR Signaling and MAPK Signaling.

Linoleic Acid can manipulate biochemical pathways Angiogenesis and TGFB Signaling. Folic Acid has biological action on biochemical pathways MAPK Signaling, MYC Signaling and PI3K-AKT-MTOR Signaling. And so on.

When treating Hemangioblastoma with chemotherapy Bevacizumab – Foods like Asparagus are recommended compared to Beetroot. This is because the active ingredients Linoleic Acid and Folic Acid in Beetroot interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Quercetin and Vitamin C contained in Asparagus support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: ASPARAGUS IS RECOMMENDED OVER BEETROOT FOR HEMANGIOBLASTOMA ON TREATMENT WITH CHEMOTHERAPY BEVACIZUMAB FOR SOME CONDITIONS.

Which Foods are Recommended for Hemangioblastoma?

Eat more fruits, Saskatoon Berry or Quince?

Fruits are an important part of many diets. The active ingredients contained in Saskatoon Berry are Quercetin, Delphinidin among others. While the active ingredients contained in Quince are Vitamin C, Oleic Acid, Chlorogenic Acid, Modified Citrus Pectin, Quercitrin and others.

Delphinidin can manipulate biochemical pathways MAPK Signaling, Angiogenesis and MYC Signaling. Quercetin has biological action on biochemical pathways Hypoxia, TGFB Signaling and PI3K-AKT-MTOR Signaling.

Quercitrin can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Linoleic Acid has biological action on biochemical pathways Angiogenesis and TGFB Signaling. And so on.

When treating Hemangioblastoma with chemotherapy Bevacizumab – Foods like Saskatoon Berry are recommended compared to Quince. This is because the active ingredients Quercitrin and Linoleic Acid in Quince interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Delphinidin and Quercetin contained in Saskatoon Berry support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: SASKATOON BERRY IS RECOMMENDED OVER QUINCE FOR HEMANGIOBLASTOMA ON TREATMENT WITH CHEMOTHERAPY BEVACIZUMAB FOR SOME CONDITIONS.

Eat more nuts, Chestnut or Brazil Nut?

Nuts are an important part of many diets. The active ingredients contained in Chestnut are Ellagic Acid, Quercetin, Vitamin C, Oleic Acid, Betulin among others. While the active ingredients contained in Brazil Nut are Oleic Acid, Vitamin E, Linolenic Acid, Folic Acid, Lecithin and others.

Betulin can manipulate biochemical pathways MAPK Signaling, Angiogenesis and MYC Signaling. Gallic Acid has biological action on biochemical pathways Hypoxia, TGFB Signaling and PI3K-AKT-MTOR Signaling.

Lecithin can manipulate biochemical pathways MAPK Signaling, Angiogenesis and MYC Signaling. Folic Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MAPK Signaling and MYC Signaling. And so on.

When treating Hemangioblastoma with chemotherapy Bevacizumab – Foods like Chestnut are recommended compared to Brazil Nut. This is because the active ingredients Lecithin and Folic Acid in Brazil Nut interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Betulin and Gallic Acid contained in Chestnut support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: CHESTNUT IS RECOMMENDED OVER BRAZIL NUT FOR HEMANGIOBLASTOMA ON TREATMENT WITH CHEMOTHERAPY BEVACIZUMAB FOR SOME CONDITIONS.

Foods for Genetic Risk of Hemangioblastoma

One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. VHL and XPC are two genes whose abnormalities are risk factors for Hemangioblastoma. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Hemangioblastoma can be used as a guide for coming up with a recommended personalized nutrition plan. For Hemangioblastoma gene VHL has causative impact on biological pathways like Angiogenesis, Carbohydrate Metabolism and Hypoxia. And XPC has a causative impact on biological pathways like DNA Repair and Post Translation Modification. Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like VHL and XPC should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes VHL and XPC should be avoided.

Eat more pulses, Fava Bean?

The active ingredients contained in Fava Bean are Quercetin, Caffeic Acid, Folic Acid, Kaempferol, Vitamin C among others.

Quercetin can manipulate biochemical pathways Hypoxia. Caffeic Acid has biological action on biochemical pathways Oncogenic Histone Methylation.

For genetic risk of Hemangioblastoma due to abnormalities in genes VHL and XPC – Foods like Fava Bean are recommended. This is because the active ingredients Quercetin and Caffeic Acid contained in Fava Bean together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: FAVA BEAN IS RECOMMENDED FOR REDUCING THE GENETIC RISK OF HEMANGIOBLASTOMA DUE TO GENES VHL AND XPC

Eat more vegetables, Chicory or Olive?

The active ingredients contained in Chicory are Quercetin, Caffeic Acid, Folic Acid, Apigenin, Kaempferol among others. While the active ingredients contained in Olive are Quercetin, Caffeic Acid, Maslinic Acid, Oleanolic Acid, Acteoside and others.

Caffeic Acid can manipulate biochemical pathways Oncogenic Histone Methylation. Quercetin has biological action on biochemical pathways Hypoxia.

Hydroxytyrosol can manipulate biochemical pathways DNA Repair. Rutin has biological action on biochemical pathways DNA Repair. And so on.

For genetic risk of Hemangioblastoma due to abnormalities in genes VHL and XPC – Foods like Chicory are recommended compared to Olive. This is because the active ingredients Hydroxytyrosol and Rutin in Olive further promote the effects of genes on the biochemical pathways. While the active ingredients Caffeic Acid and Quercetin contained in Chicory together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: CHICORY IS RECOMMENDED OVER OLIVE FOR REDUCING THE GENETIC RISK OF HEMANGIOBLASTOMA DUE TO GENES VHL AND XPC

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Eat more fruits, Black Chokeberry or Elderberry?

The active ingredients contained in Black Chokeberry are Quercetin, Caffeic Acid, Isorhamnetin among others. While the active ingredients contained in Elderberry are Quercetin, Kaempferol, Vitamin C, Isorhamnetin, Linolenic Acid and others.

Caffeic Acid can manipulate biochemical pathways Oncogenic Histone Methylation. Quercetin has biological action on biochemical pathways Hypoxia.

Rutin can manipulate biochemical pathways DNA Repair. Oleic Acid has biological action on biochemical pathways DNA Repair. And so on.

For genetic risk of Hemangioblastoma due to abnormalities in genes VHL and XPC – Foods like Black Chokeberry are recommended compared to Elderberry. This is because the active ingredients Rutin and Oleic Acid in Elderberry further promote the effects of genes on the biochemical pathways. While the active ingredients Caffeic Acid and Quercetin contained in Black Chokeberry together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: BLACK CHOKEBERRY IS RECOMMENDED OVER ELDERBERRY FOR REDUCING THE GENETIC RISK OF HEMANGIOBLASTOMA DUE TO GENES VHL AND XPC

Eat more nuts, Cashew Nut?

The active ingredients contained in Cashew Nut are Folic Acid, Vitamin C, Gallic Acid among others.

Vitamin C can manipulate biochemical pathways Hypoxia. Gallic Acid has biological action on biochemical pathways Hypoxia.

For genetic risk of Hemangioblastoma due to abnormalities in genes VHL and XPC – Foods like Cashew Nut are recommended. This is because the active ingredients Vitamin C and Gallic Acid contained in Cashew Nut together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: CASHEW NUT IS RECOMMENDED FOR REDUCING THE GENETIC RISK OF HEMANGIOBLASTOMA DUE TO GENES VHL AND XPC


In Summary

An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.

“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.

You can get started NOW and design a personalized nutrition plan for Hemangioblastoma by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

sample-report


References

Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

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