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What Foods are Recommended for Cancer?
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.

Which Foods are Recommended for Low-grade Fibromyxoid Sarcoma?

Aug 23, 2022

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Home » Blogs » Which Foods are Recommended for Low-grade Fibromyxoid Sarcoma?

Highlights

No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Low-grade Fibromyxoid Sarcoma when undergoing chemotherapy or when you determine you have a genetic risk for developing Low-grade Fibromyxoid Sarcoma because of CDKN2A and KMT2B gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.

There is no one answer to this question for cancers such as Low-grade Fibromyxoid Sarcoma which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.

In short – the process to answer questions like “Should I Avoid eating fruit Cherry” or “Include fruit Bilberry in my diet” or “Should I reduce consumption of vegetable Radish” or “Can I take Myricetin and Sumac supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.

RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO LOW-GRADE FIBROMYXOID SARCOMA, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.

The overall objective of personalized nutrition for Low-grade Fibromyxoid Sarcoma is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.

RECOMMENDATION: UPDATE YOUR NUTRITION FOR LOW-GRADE FIBROMYXOID SARCOMA, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.



About Low-grade Fibromyxoid Sarcoma

cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.

Following key highlights are derived from clinical data for Low-grade Fibromyxoid Sarcoma from cBioPortal. 64.3% of males and 35.7% of females were the distribution of gender in these clinical studies. From a patient sample size of 18; the top genes with mutations and other abnormalities for Low-grade Fibromyxoid Sarcoma include genes CDKN2A, KMT2B, PIK3CG, IRS2 and LRP2. The occurrence frequency distribution for these genes respectively is 12.5%, 12.5%, 12.5%, 12.5% and 12.5%. These tumor genetic details of Low-grade Fibromyxoid Sarcoma are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Low-grade Fibromyxoid Sarcoma.

Significance of Nutrition for Low-grade Fibromyxoid Sarcoma

All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Low-grade Fibromyxoid Sarcoma. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.

For example Cherry includes active ingredients Quercetin, Beta-sitosterol, Oleic Acid, Genistein, Glucaric Acid and others. And Bilberry contains active ingredients Myricetin, Resveratrol, Quercetin, Chlorogenic Acid, Asperuloside and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.

For cancers like Low-grade Fibromyxoid Sarcoma, activation or inhibition of selected biochemical pathways like PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints, Cell Cycle, Mismatch Repair plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Low-grade Fibromyxoid Sarcoma, while eating some other foods and supplements may not be recommended.

One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

For cancers like Low-grade Fibromyxoid Sarcoma, activation or inhibition of selected biochemical pathways like PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints, Cell Cycle, Mismatch Repair plays an important role in driving cancer growth.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR LOW-GRADE FIBROMYXOID SARCOMA – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.

Foods for Low-grade Fibromyxoid Sarcoma undergoing chemotherapy treatment

In Low-grade Fibromyxoid Sarcoma – the genes CDKN2A, KMT2B, PIK3CG, IRS2 and LRP2 have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Low-grade Fibromyxoid Sarcoma are PI3K-AKT-MTOR Signaling and others. Bevacizumab is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers PI3K-AKT-MTOR Signaling so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.

RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.

Eat more pulses, Common Pea or Common Bean?

Pulses are an important part of many diets. The active ingredients contained in Common Pea are Daidzein, Lupeol, Beta-sitosterol, Oleic Acid, Genistein among others. While the active ingredients contained in Common Bean are Apigenin, Oleic Acid, Genistein, Gamma-linolenic Acid, Kaempferol and others.

Beta-sitosterol can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Vitamin C has biological action on biochemical pathways PI3K-AKT-MTOR Signaling.

Pelargonidin can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Folic Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.

When treating Low-grade Fibromyxoid Sarcoma with chemotherapy Bevacizumab – Foods like Common Pea are recommended compared to Common Bean. This is because the active ingredients Pelargonidin and Folic Acid in Common Bean interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Beta-sitosterol and Vitamin C contained in Common Pea support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: COMMON PEA IS RECOMMENDED OVER COMMON BEAN FOR LOW-GRADE FIBROMYXOID SARCOMA ON TREATMENT WITH CHEMOTHERAPY BEVACIZUMAB FOR SOME CONDITIONS.

Eat more vegetables, Onion or Radish?

Vegetables are an important part of many diets. The active ingredients contained in Onion are Myricetin, Vanillic Acid, Quercetin, Beta-sitosterol, Kaempferol among others. While the active ingredients contained in Radish are Quercetin, Beta-sitosterol, Oleic Acid, Kaempferol, Salicylic Acid and others.

Quercetin can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Myricetin has biological action on biochemical pathways PI3K-AKT-MTOR Signaling.

Pelargonidin can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Folic Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.

When treating Low-grade Fibromyxoid Sarcoma with chemotherapy Bevacizumab – Foods like Onion are recommended compared to Radish. This is because the active ingredients Pelargonidin and Folic Acid in Radish interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Quercetin and Myricetin contained in Onion support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: ONION IS RECOMMENDED OVER RADISH FOR LOW-GRADE FIBROMYXOID SARCOMA ON TREATMENT WITH CHEMOTHERAPY BEVACIZUMAB FOR SOME CONDITIONS.

Which Foods are Recommended for Low grade Fibromyxoid Sarcoma?

Eat more fruits, Bilberry or Cherry?

Fruits are an important part of many diets. The active ingredients contained in Bilberry are Myricetin, Resveratrol, Quercetin, Chlorogenic Acid, Asperuloside among others. While the active ingredients contained in Cherry are Quercetin, Beta-sitosterol, Oleic Acid, Genistein, Glucaric Acid and others.

Chlorogenic Acid can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Delphinidin has biological action on biochemical pathways PI3K-AKT-MTOR Signaling.

Shikimic Acid can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Pelargonidin has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.

When treating Low-grade Fibromyxoid Sarcoma with chemotherapy Bevacizumab – Foods like Bilberry are recommended compared to Cherry. This is because the active ingredients Shikimic Acid and Pelargonidin in Cherry interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Chlorogenic Acid and Delphinidin contained in Bilberry support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: BILBERRY IS RECOMMENDED OVER CHERRY FOR LOW-GRADE FIBROMYXOID SARCOMA ON TREATMENT WITH CHEMOTHERAPY BEVACIZUMAB FOR SOME CONDITIONS.

Eat more nuts, Walnut or Peanut?

Nuts are an important part of many diets. The active ingredients contained in Walnut are Myricetin, Ellagic Acid, Juglone, Quercetin, Beta-sitosterol among others. While the active ingredients contained in Peanut are Vanillic Acid, Quercetin, Beta-sitosterol, Oleic Acid, Vitamin E and others.

Myricetin can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Ellagic Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling.

Lecithin can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Folic Acid has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.

When treating Low-grade Fibromyxoid Sarcoma with chemotherapy Bevacizumab – Foods like Walnut are recommended compared to Peanut. This is because the active ingredients Lecithin and Folic Acid in Peanut interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Myricetin and Ellagic Acid contained in Walnut support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: WALNUT IS RECOMMENDED OVER PEANUT FOR LOW-GRADE FIBROMYXOID SARCOMA ON TREATMENT WITH CHEMOTHERAPY BEVACIZUMAB FOR SOME CONDITIONS.

Foods for Genetic Risk of Low-grade Fibromyxoid Sarcoma

One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. CDKN2A and KMT2B are two genes whose abnormalities are risk factors for Low-grade Fibromyxoid Sarcoma. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Low-grade Fibromyxoid Sarcoma can be used as a guide for coming up with a recommended personalized nutrition plan. For Low-grade Fibromyxoid Sarcoma gene CDKN2A has causative impact on biological pathways like Cell Cycle Checkpoints and Cell Cycle. And KMT2B has a causative impact on biological pathways like Amino Acid Metabolism and Oncogenic Histone Methylation. Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like CDKN2A and KMT2B should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes CDKN2A and KMT2B should be avoided.

Eat more pulses, Scarlet Bean or Soy Bean?

The active ingredients contained in Scarlet Bean are Beta-sitosterol, Vitamin C, Linolenic Acid, Oleic Acid, Stigmasterol among others. While the active ingredients contained in Soy Bean are Lupeol, Vitamin E, Daidzein, Beta-sitosterol, Quercetin and others.

Beta-sitosterol can manipulate biochemical pathways Apoptosis, Cell Cycle and MYC Signaling. Vitamin C has biological action on biochemical pathways P53 Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling.

Aescin can manipulate biochemical pathways Cell Cycle Checkpoints and Cell Cycle. Lecithin has biological action on biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. And so on.

For genetic risk of Low-grade Fibromyxoid Sarcoma due to abnormalities in genes CDKN2A and KMT2B – Foods like Scarlet Bean are recommended compared to Soy Bean. This is because the active ingredients Aescin and Lecithin in Soy Bean further promote the effects of genes on the biochemical pathways. While the active ingredients Beta-sitosterol and Vitamin C contained in Scarlet Bean together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: SCARLET BEAN IS RECOMMENDED OVER SOY BEAN FOR REDUCING THE GENETIC RISK OF LOW-GRADE FIBROMYXOID SARCOMA DUE TO GENES CDKN2A AND KMT2B

Eat more vegetables, Cassava or Celery?

The active ingredients contained in Cassava are Beta-sitosterol, Vitamin C, Linolenic Acid, Oleic Acid, Linoleic Acid among others. While the active ingredients contained in Celery are Apigenin, Quercetin, Vitamin C, Linolenic Acid, Oleic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, Cell Cycle and MYC Signaling. Beta-sitosterol has biological action on biochemical pathways P53 Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling.

Luteolin can manipulate biochemical pathways MYC Signaling. Cynaroside has biological action on biochemical pathways Oncogenic Cancer Epigenetics. And so on.

For genetic risk of Low-grade Fibromyxoid Sarcoma due to abnormalities in genes CDKN2A and KMT2B – Foods like Cassava are recommended compared to Celery. This is because the active ingredients Luteolin and Cynaroside in Celery further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Cassava together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: CASSAVA IS RECOMMENDED OVER CELERY FOR REDUCING THE GENETIC RISK OF LOW-GRADE FIBROMYXOID SARCOMA DUE TO GENES CDKN2A AND KMT2B

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Eat more fruits, Feijoa or Grape?

The active ingredients contained in Feijoa are Lycopene, Vitamin C, Casuarinin, Folic Acid among others. While the active ingredients contained in Grape are Lupeol, Vitamin E, Beta-sitosterol, Pterostilbene, Vitamin C and others.

Vitamin C can manipulate biochemical pathways Apoptosis, Cell Cycle and MYC Signaling. Lycopene has biological action on biochemical pathways P53 Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling.

Resveratrol can manipulate biochemical pathways P53 Signaling. Pelargonidin has biological action on biochemical pathways MYC Signaling, Cell Cycle Checkpoints and Cell Cycle. And so on.

For genetic risk of Low-grade Fibromyxoid Sarcoma due to abnormalities in genes CDKN2A and KMT2B – Foods like Feijoa are recommended compared to Grape. This is because the active ingredients Resveratrol and Pelargonidin in Grape further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Lycopene contained in Feijoa together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: FEIJOA IS RECOMMENDED OVER GRAPE FOR REDUCING THE GENETIC RISK OF LOW-GRADE FIBROMYXOID SARCOMA DUE TO GENES CDKN2A AND KMT2B

Eat more nuts, Pecan Nut or Acorn?

The active ingredients contained in Pecan Nut are Vitamin E, Linolenic Acid, Oleic Acid, Cianidanol, Linoleic Acid among others. While the active ingredients contained in Acorn are Beta-sitosterol, Quercetin, Vitamin C, Beta-carotene, Quercitrin and others.

Vitamin E can manipulate biochemical pathways Apoptosis, Cell Cycle and MYC Signaling. Cianidanol has biological action on biochemical pathways P53 Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling.

Vitamin B2 can manipulate biochemical pathways Oncogenic Cancer Epigenetics. Folic Acid has biological action on biochemical pathways Apoptosis, MYC Signaling and P53 Signaling. And so on.

For genetic risk of Low-grade Fibromyxoid Sarcoma due to abnormalities in genes CDKN2A and KMT2B – Foods like Pecan Nut are recommended compared to Acorn. This is because the active ingredients Vitamin B2 and Folic Acid in Acorn further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin E and Cianidanol contained in Pecan Nut together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: PECAN NUT IS RECOMMENDED OVER ACORN FOR REDUCING THE GENETIC RISK OF LOW-GRADE FIBROMYXOID SARCOMA DUE TO GENES CDKN2A AND KMT2B


In Summary

An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.

“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.

You can get started NOW and design a personalized nutrition plan for Low-grade Fibromyxoid Sarcoma by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

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References

Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

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