Highlights
No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Mucinous Adenocarcinoma Of The Appendix when undergoing chemotherapy or when you determine you have a genetic risk for developing Mucinous Adenocarcinoma Of The Appendix because of GNAS and SMAD2 gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.
There is no one answer to this question for cancers such as Mucinous Adenocarcinoma Of The Appendix which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.
In short – the process to answer questions like “Should I Avoid eating fruit Sea Buckthorn” or “Include fruit Blueberry in my diet” or “Should I reduce consumption of vegetable Chinese Mustard” or “Can I take Stevia and D-limonene supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.
RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO MUCINOUS ADENOCARCINOMA OF THE APPENDIX, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.
The overall objective of personalized nutrition for Mucinous Adenocarcinoma Of The Appendix is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.
RECOMMENDATION: UPDATE YOUR NUTRITION FOR MUCINOUS ADENOCARCINOMA OF THE APPENDIX, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.
About Mucinous Adenocarcinoma Of The Appendix
cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.
Following key highlights are derived from clinical data for Mucinous Adenocarcinoma Of The Appendix from cBioPortal. The patients enrolled in the studies for Mucinous Adenocarcinoma Of The Appendix are in ages between 73 to 73 with an average age of 73. 49.7% of males and 50.3% of females were the distribution of gender in these clinical studies. From a patient sample size of 163; the top genes with mutations and other abnormalities for Mucinous Adenocarcinoma Of The Appendix include genes KRAS, GNAS, TP53, SMAD2 and AKT1. The occurrence frequency distribution for these genes respectively is 56.9%, 33.8%, 16.9%, 12.3% and 6.2%. These tumor genetic details of Mucinous Adenocarcinoma Of The Appendix are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Mucinous Adenocarcinoma Of The Appendix.
Significance of Nutrition for Mucinous Adenocarcinoma Of The Appendix
All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Mucinous Adenocarcinoma Of The Appendix. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.
For example Sea Buckthorn includes active ingredients Isorhamnetin, Beta-sitosterol, Oleic Acid, Vitamin C, Linolenic Acid and others. And Blueberry contains active ingredients Quercetin, Resveratrol, Vitamin E, Delphinidin, Hyperoside and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.
For cancers like Mucinous Adenocarcinoma Of The Appendix, activation or inhibition of selected biochemical pathways like RAS-RAF Signaling, Cell Cycle, PI3K-AKT-MTOR Signaling, MAPK Signaling plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Mucinous Adenocarcinoma Of The Appendix, while eating some other foods and supplements may not be recommended.
One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR MUCINOUS ADENOCARCINOMA OF THE APPENDIX – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.
Foods for Mucinous Adenocarcinoma Of The Appendix undergoing chemotherapy treatment
In Mucinous Adenocarcinoma Of The Appendix – the genes KRAS, GNAS, TP53, SMAD2 and AKT1 have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Mucinous Adenocarcinoma Of The Appendix are RAS-RAF Signaling, Cell Cycle, Growth Factor Signaling and others. Radiation is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers RAS-RAF Signaling, Cell Cycle, Growth Factor Signaling so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.
RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.
Eat more pulses, Scarlet Bean or Lima Bean?
Pulses are an important part of many diets. The active ingredients contained in Scarlet Bean are Beta-sitosterol, Oleic Acid, Vitamin C, Linolenic Acid, Genistein among others. While the active ingredients contained in Lima Bean are Oleic Acid, Vitamin C, Genistein, Vitamin A, Linoleic Acid and others.
Beta-sitosterol can manipulate biochemical pathways NFKB Signaling, Cell Cycle and Cell Survival. Vitamin C has biological action on biochemical pathways MYC Signaling, MAPK Signaling and PI3K-AKT-MTOR Signaling.
Genistein can manipulate biochemical pathways DNA Repair. Vitamin A has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.
When treating Mucinous Adenocarcinoma Of The Appendix with chemotherapy Radiation – Foods like Scarlet Bean are recommended compared to Lima Bean. This is because the active ingredients Genistein and Vitamin A in Lima Bean interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Beta-sitosterol and Vitamin C contained in Scarlet Bean support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.
RECOMMENDATION: SCARLET BEAN IS RECOMMENDED OVER LIMA BEAN FOR MUCINOUS ADENOCARCINOMA OF THE APPENDIX ON TREATMENT WITH CHEMOTHERAPY RADIATION FOR SOME CONDITIONS.
Eat more vegetables, Asparagus or Chinese Mustard?
Vegetables are an important part of many diets. The active ingredients contained in Asparagus are Quercetin, Isorhamnetin, Oleic Acid, Vitamin C, Linolenic Acid among others. While the active ingredients contained in Chinese Mustard are Quercetin, Isorhamnetin, Indole-3-carbinol, Kaempferol, Vitamin A and others.
Quercetin can manipulate biochemical pathways NFKB Signaling, DNA Repair and Growth Factor Signaling. Isorhamnetin has biological action on biochemical pathways Cell Cycle, Cell Survival and MYC Signaling.
Vitamin A can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Indole-3-carbinol has biological action on biochemical pathways DNA Repair. And so on.
When treating Mucinous Adenocarcinoma Of The Appendix with chemotherapy Radiation – Foods like Asparagus are recommended compared to Chinese Mustard. This is because the active ingredients Vitamin A and Indole-3-carbinol in Chinese Mustard interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Quercetin and Isorhamnetin contained in Asparagus support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.
RECOMMENDATION: ASPARAGUS IS RECOMMENDED OVER CHINESE MUSTARD FOR MUCINOUS ADENOCARCINOMA OF THE APPENDIX ON TREATMENT WITH CHEMOTHERAPY RADIATION FOR SOME CONDITIONS.
Eat more fruits, Blueberry or Sea Buckthorn?
Fruits are an important part of many diets. The active ingredients contained in Blueberry are Quercetin, Resveratrol, Vitamin E, Delphinidin, Hyperoside among others. While the active ingredients contained in Sea Buckthorn are Isorhamnetin, Beta-sitosterol, Oleic Acid, Vitamin C, Linolenic Acid and others.
Gallic Acid can manipulate biochemical pathways NFKB Signaling, DNA Repair and Cell Cycle. Vitamin C has biological action on biochemical pathways MYC Signaling, MAPK Signaling and PI3K-AKT-MTOR Signaling.
Vitamin A can manipulate biochemical pathways PI3K-AKT-MTOR Signaling. Linoleic Acid has biological action on biochemical pathways TGFB Signaling and Angiogenesis. And so on.
When treating Mucinous Adenocarcinoma Of The Appendix with chemotherapy Radiation – Foods like Blueberry are recommended compared to Sea Buckthorn. This is because the active ingredients Vitamin A and Linoleic Acid in Sea Buckthorn interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Gallic Acid and Vitamin C contained in Blueberry support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.
RECOMMENDATION: BLUEBERRY IS RECOMMENDED OVER SEA BUCKTHORN FOR MUCINOUS ADENOCARCINOMA OF THE APPENDIX ON TREATMENT WITH CHEMOTHERAPY RADIATION FOR SOME CONDITIONS.
Eat more nuts, Almond or Acorn?
Nuts are an important part of many diets. The active ingredients contained in Almond are Quercetin, Vitamin E, Beta-sitosterol, Oleic Acid, Salicylic Acid among others. While the active ingredients contained in Acorn are Quercetin, Gallic Acid, Beta-sitosterol, Vitamin C, Beta-carotene and others.
Beta-sitosterol can manipulate biochemical pathways NFKB Signaling, Cell Cycle and Cell Survival. Quercetin has biological action on biochemical pathways DNA Repair, Growth Factor Signaling and TGFB Signaling.
Beta-carotene can manipulate biochemical pathways MAPK Signaling and PI3K-AKT-MTOR Signaling. Vitamin A has biological action on biochemical pathways PI3K-AKT-MTOR Signaling. And so on.
When treating Mucinous Adenocarcinoma Of The Appendix with chemotherapy Radiation – Foods like Almond are recommended compared to Acorn. This is because the active ingredients Beta-carotene and Vitamin A in Acorn interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Beta-sitosterol and Quercetin contained in Almond support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.
RECOMMENDATION: ALMOND IS RECOMMENDED OVER ACORN FOR MUCINOUS ADENOCARCINOMA OF THE APPENDIX ON TREATMENT WITH CHEMOTHERAPY RADIATION FOR SOME CONDITIONS.

Foods for Genetic Risk of Mucinous Adenocarcinoma Of The Appendix
One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. GNAS and SMAD2 are two genes whose abnormalities are risk factors for Mucinous Adenocarcinoma Of The Appendix. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Mucinous Adenocarcinoma Of The Appendix can be used as a guide for coming up with a recommended personalized nutrition plan. For Mucinous Adenocarcinoma Of The Appendix gene GNAS has causative impact on biological pathways like G-protein-coupled Receptor Signaling, Reproductive Hormone Signaling and Gonadotropin-releasing hormone. And SMAD2 has a causative impact on biological pathways like TGFB Signaling, Cell Cycle Checkpoints and Inflammation. Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like GNAS and SMAD2 should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes GNAS and SMAD2 should be avoided.
Eat more pulses, Winged Bean or Moth Bean?
The active ingredients contained in Winged Bean are Betulinic Acid, Oleic Acid, Linolenic Acid, Vitamin C, Vitamin A among others. While the active ingredients contained in Moth Bean are Oleic Acid, Beta-sitosterol, Linolenic Acid, Stigmasterol, Vitamin A and others.
Betulinic Acid can manipulate biochemical pathways MYC Signaling, Cell Cycle Checkpoints and MAPK Signaling. Vitamin C has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, RAS-RAF Signaling and MYC Signaling.
Linoleic Acid can manipulate biochemical pathways Extracellular Matrix Remodelling. Folic Acid has biological action on biochemical pathways MYC Signaling, Cell Cycle Checkpoints and MAPK Signaling. And so on.
For genetic risk of Mucinous Adenocarcinoma Of The Appendix due to abnormalities in genes GNAS and SMAD2 – Foods like Winged Bean are recommended compared to Moth Bean. This is because the active ingredients Linoleic Acid and Folic Acid in Moth Bean further promote the effects of genes on the biochemical pathways. While the active ingredients Betulinic Acid and Vitamin C contained in Winged Bean together have a canceling effect of genes on the biochemical pathways.
RECOMMENDATION: WINGED BEAN IS RECOMMENDED OVER MOTH BEAN FOR REDUCING THE GENETIC RISK OF MUCINOUS ADENOCARCINOMA OF THE APPENDIX DUE TO GENES GNAS AND SMAD2
Eat more vegetables, Jicama or Lotus?
The active ingredients contained in Jicama are Vitamin C, Vitamin B3, Beta-carotene, Vitamin A, Folic Acid among others. While the active ingredients contained in Lotus are Oleic Acid, Beta-sitosterol, Quercetin, Linolenic Acid, Vitamin C and others.
Vitamin C can manipulate biochemical pathways MYC Signaling, Cell Cycle Checkpoints and MAPK Signaling. Vitamin B3 has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, MYC Signaling and Cell Cycle Checkpoints.
Fisetin can manipulate biochemical pathways MYC Signaling. Linoleic Acid has biological action on biochemical pathways Extracellular Matrix Remodelling. And so on.
For genetic risk of Mucinous Adenocarcinoma Of The Appendix due to abnormalities in genes GNAS and SMAD2 – Foods like Jicama are recommended compared to Lotus. This is because the active ingredients Fisetin and Linoleic Acid in Lotus further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Vitamin B3 contained in Jicama together have a canceling effect of genes on the biochemical pathways.
RECOMMENDATION: JICAMA IS RECOMMENDED OVER LOTUS FOR REDUCING THE GENETIC RISK OF MUCINOUS ADENOCARCINOMA OF THE APPENDIX DUE TO GENES GNAS AND SMAD2
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
Eat more fruits, Orange or Huckleberry?
The active ingredients contained in Orange are D-limonene, Modified Citrus Pectin, Linalool, Glucaric Acid, Hesperidin among others. While the active ingredients contained in Huckleberry are Resveratrol, Quercetin, Vitamin C, Delphinidin, P-coumaric Acid and others.
D-limonene can manipulate biochemical pathways Small Molecule Transport, MYC Signaling and Cell Cycle Checkpoints. Glucaric Acid has biological action on biochemical pathways RAS-RAF Signaling, MAPK Signaling and PI3K-AKT-MTOR Signaling.
Ferulic Acid can manipulate biochemical pathways DNA Repair. Pelargonidin has biological action on biochemical pathways MYC Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling. And so on.
For genetic risk of Mucinous Adenocarcinoma Of The Appendix due to abnormalities in genes GNAS and SMAD2 – Foods like Orange are recommended compared to Huckleberry. This is because the active ingredients Ferulic Acid and Pelargonidin in Huckleberry further promote the effects of genes on the biochemical pathways. While the active ingredients D-limonene and Glucaric Acid contained in Orange together have a canceling effect of genes on the biochemical pathways.
RECOMMENDATION: ORANGE IS RECOMMENDED OVER HUCKLEBERRY FOR REDUCING THE GENETIC RISK OF MUCINOUS ADENOCARCINOMA OF THE APPENDIX DUE TO GENES GNAS AND SMAD2
Eat more nuts, Pine Nut or Peanut?
The active ingredients contained in Pine Nut are Oleic Acid, Beta-sitosterol, Vitamin E, Linolenic Acid, Vitamin A among others. While the active ingredients contained in Peanut are Oleic Acid, Beta-sitosterol, Vitamin E, Quercetin, Linolenic Acid and others.
Beta-sitosterol can manipulate biochemical pathways MYC Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling. Vitamin K has biological action on biochemical pathways MYC Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling.
Lecithin can manipulate biochemical pathways MYC Signaling, MAPK Signaling and PI3K-AKT-MTOR Signaling. Vitamin E has biological action on biochemical pathways DNA Repair. And so on.
For genetic risk of Mucinous Adenocarcinoma Of The Appendix due to abnormalities in genes GNAS and SMAD2 – Foods like Pine Nut are recommended compared to Peanut. This is because the active ingredients Lecithin and Vitamin E in Peanut further promote the effects of genes on the biochemical pathways. While the active ingredients Beta-sitosterol and Vitamin K contained in Pine Nut together have a canceling effect of genes on the biochemical pathways.
RECOMMENDATION: PINE NUT IS RECOMMENDED OVER PEANUT FOR REDUCING THE GENETIC RISK OF MUCINOUS ADENOCARCINOMA OF THE APPENDIX DUE TO GENES GNAS AND SMAD2

In Summary
An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.
“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.
The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.
You can get started NOW and design a personalized nutrition plan for Mucinous Adenocarcinoma Of The Appendix by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

References
- Ntrk Msk 2019
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- β-Sitosterol targets Trx/Trx1 reductase to induce apoptosis in A549 cells via ROS mediated mitochondrial dysregulation and p53 activation.
- Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
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- Vitamin A regulates Akt signaling through the phospholipid fatty acid composition.
- Gallic acid, a phenolic compound, exerts anti-angiogenic effects via the PTEN/AKT/HIF-1α/VEGF signaling pathway in ovarian cancer cells.
- Excess Linoleic Acid Increases Collagen I/III Ratio and Stiffens” the Heart Muscle Following High Fat Diets.”
- A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
- Isorhamnetin Induces Cell Cycle Arrest and Apoptosis Via Reactive Oxygen Species-Mediated AMP-Activated Protein Kinase Signaling Pathway Activation in Human Bladder Cancer Cells.
- Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
- Growth stimulation of human pulmonary adenocarcinoma cells and small airway epithelial cells by beta-carotene via activation of cAMP, PKA, CREB and ERK1/2.
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- Legionella pneumophila serogroup 12 pneumonia in a renal transplant recipient: case report and environmental observations.
- Pelargonidin suppresses adipogenesis in 3T3-L1 cells through inhibition of PPAR-γ signaling pathway.
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- Research progress on the anticancer effects of vitamin K2.
- The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras.
- Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis.
- HyperFoods: Machine intelligent mapping of cancer-beating molecules in foods.
- Fisetin: a dietary antioxidant for health promotion.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.