addonfinal2
What Foods are Recommended for Cancer?
is a very common question. Personalized Nutrition Plans are foods and supplements which are personalized to a cancer indication, genes, any treatments and lifestyle conditions.

Which Foods are Recommeded for Protoplasmic Astrocytoma?

Aug 16, 2022

4.7
(24)
Estimated reading time: 15 minutes
Home » Blogs » Which Foods are Recommeded for Protoplasmic Astrocytoma?

Highlights

No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Protoplasmic Astrocytoma when undergoing chemotherapy or when you determine you have a genetic risk for developing Protoplasmic Astrocytoma because of FOXO3 and IDH1 gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.

There is no one answer to this question for cancers such as Protoplasmic Astrocytoma which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.

In short – the process to answer questions like “Should I Avoid eating fruit Lingonberry” or “Include fruit Persimmon in my diet” or “Should I reduce consumption of vegetable Endive” or “Can I take Dim and Birch supplements” is not as simple as internet searches. The process is very complex and answers are based on knowhow of genetics, action of treatments, active ingredients in foods and their associated biological action. Finally the answer to the nutrition question needs to be personalized for you.

RECOMMENDATION: PERSONALIZE YOUR FOODS AND SUPPLEMENTS TO PROTOPLASMIC ASTROCYTOMA, TREATMENTS, GENETIC INFORMATION, AND OTHER CONDITIONS.

The overall objective of personalized nutrition for Protoplasmic Astrocytoma is to minimize foods and nutritional supplements which have adverse interactions with cancer molecular drivers and ongoing treatments. And identify those foods and supplements which have a beneficial action. Whenever there are changes in treatments or diagnosis – it is important to remember that your foods and supplements need re-evaluation. And the answers to the nutrition question could be different based on the new context.

RECOMMENDATION: UPDATE YOUR NUTRITION FOR PROTOPLASMIC ASTROCYTOMA, WHEN TREATMENTS, DISEASE STATUS AND OTHER CONDITIONS CHANGE.



About Protoplasmic Astrocytoma

cBioPortal is one source of collection of cancer patient data from clinical trials across 350 plus cancer indications. The data from each clinical trial includes the clinical trial name and study details like number of patients, ages, gender, ethnicity, treatments, tumor site, genetic aberrations found and analysis of all the data. The cBioPortal for Cancer Genomics was originally developed at Memorial Sloan Kettering Cancer Center (MSK). The public cBioPortal site is hosted by the Center for Molecular Oncology at MSK – https://www.cbioportal.org/about.

Following key highlights are derived from clinical data for Protoplasmic Astrocytoma from cBioPortal. The top genes with mutations and other abnormalities for Protoplasmic Astrocytoma include genes TP53, IDH1, ATRX, FOXO3 and TERT. The occurrence frequency distribution for these genes respectively is 46.8%, 46.8%, 40.4%, 38.7% and 19.8%. These tumor genetic details of Protoplasmic Astrocytoma are mapped to molecular biochemical pathway drivers of cancer thereby providing definition of characteristic features of Protoplasmic Astrocytoma.

Significance of Nutrition for Protoplasmic Astrocytoma

All foods and nutritional supplements consist of a collection of one or more active chemical ingredients in different proportions and quantities. The action of some active ingredients in a food can have adverse interactions while other active ingredients in the same food may be supportive from the context of Protoplasmic Astrocytoma. Hence the same food has good and not-so-good actions and analysis of combined effect will be needed to come up with a personalized nutrition plan.

For example Lingonberry includes active ingredients Quercetin, Resveratrol, Hyperoside, Caffeic Acid, Vitamin C and others. And Persimmon contains active ingredients Quercetin, Lupeol, Betulinic Acid, Lycopene, Vitamin C and others. It is likely that some of these active ingredients of the same food could have opposing effects and hence it is recommended to identify recommended foods based on analysis of all high quantity ingredients contained in foods.

For cancers like Protoplasmic Astrocytoma, activation or inhibition of selected biochemical pathways like DNA Repair, Angiogenesis, PI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics plays an important role in driving cancer growth. Similarly different treatments work via different molecular actions which should never be canceled out by your foods and supplements. The foods and nutritional supplements contain different active ingredients each of which have a specific molecular action on different biochemical pathways. Hence, eating some foods and nutritional supplements would be recommended with a specific treatment of Protoplasmic Astrocytoma, while eating some other foods and supplements may not be recommended.

One common mistake when finding foods to eat or not – is to consider only a few active ingredients contained in foods based on internet searches and ignore the rest. Because different active ingredients contained in foods may have opposing effects on relevant biochemical pathways – it is recommended to consider all the high quantity active ingredients that are present in significant and much larger than trace amounts in the food.

RECOMMENDATION: TO FIND RECOMMENDED AND NON-RECOMMENDED FOODS FOR PROTOPLASMIC ASTROCYTOMA – CONSIDER HIGH QUANTITY ACTIVE INGREDIENTS CONTAINED IN FOODS.

Foods for Protoplasmic Astrocytoma undergoing chemotherapy treatment

In Protoplasmic Astrocytoma – the genes TP53, IDH1, ATRX, FOXO3 and TERT have high occurrences of genomic abnormalities. Not all of these genes necessarily are relevant for cancer – though they have been reported. Some of these genes directly or indirectly end up manipulating different cancer related biochemical biological pathways. Some of the pathways which are relevant drivers for Protoplasmic Astrocytoma are DNA Repair, Angiogenesis, Hypoxia and others. Temozolomide is one of the chemotherapies used for cancer treatment. The intent of treatment is to negate or cancel out effects of biochemical pathway drivers DNA Repair, Angiogenesis, Hypoxia so as to reduce disease progression and inhibit growth. Those foods whose combined action of active ingredients support treatment action and do not enhance disease drivers are recommended foods and supplements which will be included in personalized nutrition. And similarly – those foods whose combined action of active ingredients is not supportive of treatment action but end up promoting disease drives will not be recommended in your personalized nutrition plan.

RECOMMENDATION: AVOID SUPPLEMENTS AND FOODS WHICH ARE NOT SUPPORTIVE OF CANCER TREATMENT ACTION AND RATHER ENHANCE DISEASE DRIVERS.

Eat more pulses, Common Pea or Lima Bean?

Pulses are an important part of many diets. The active ingredients contained in Common Pea are Lupeol, Delphinidin, Daidzein, Vitamin C, Beta-sitosterol among others. While the active ingredients contained in Lima Bean are Vitamin C, Genistein, Oleic Acid, Linoleic Acid, Vitamin A and others.

Vitamin C can manipulate biochemical pathways Growth Factor Signaling, Cell Cycle and MYC Signaling. Beta-sitosterol has biological action on biochemical pathways NFKB Signaling, Microtubule Dynamics and Cell Survival.

Genistein can manipulate biochemical pathways DNA Repair and Oxidative Stress. Vitamin A has biological action on biochemical pathways TGFB Signaling, PI3K-AKT-MTOR Signaling and Extracellular Matrix Remodelling. And so on.

When treating Protoplasmic Astrocytoma with chemotherapy Temozolomide – Foods like Common Pea are recommended compared to Lima Bean. This is because the active ingredients Genistein and Vitamin A in Lima Bean interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Vitamin C and Beta-sitosterol contained in Common Pea support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: COMMON PEA IS RECOMMENDED OVER LIMA BEAN FOR PROTOPLASMIC ASTROCYTOMA ON TREATMENT WITH CHEMOTHERAPY TEMOZOLOMIDE FOR SOME CONDITIONS.

Eat more vegetables, Jicama or Endive?

Vegetables are an important part of many diets. The active ingredients contained in Jicama are Vitamin C, Beta-carotene, Vitamin B3, Vitamin A, Folic Acid among others. While the active ingredients contained in Endive are Quercetin, Vitamin C, Kaempferol, Oleic Acid, Linolenic Acid and others.

Vitamin C can manipulate biochemical pathways Growth Factor Signaling, Cell Cycle and MYC Signaling. Beta-carotene has biological action on biochemical pathways NFKB Signaling, Stem Cell Signaling and Microtubule Dynamics.

Vitamin A can manipulate biochemical pathways TGFB Signaling, PI3K-AKT-MTOR Signaling and Extracellular Matrix Remodelling. Quercetin has biological action on biochemical pathways Oxidative Stress. And so on.

When treating Protoplasmic Astrocytoma with chemotherapy Temozolomide – Foods like Jicama are recommended compared to Endive. This is because the active ingredients Vitamin A and Quercetin in Endive interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Vitamin C and Beta-carotene contained in Jicama support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: JICAMA IS RECOMMENDED OVER ENDIVE FOR PROTOPLASMIC ASTROCYTOMA ON TREATMENT WITH CHEMOTHERAPY TEMOZOLOMIDE FOR SOME CONDITIONS.

Which Foods are Recommended for Protoplasmic Astrocytoma?

Eat more fruits, Persimmon or Lingonberry?

Fruits are an important part of many diets. The active ingredients contained in Persimmon are Quercetin, Lupeol, Betulinic Acid, Lycopene, Vitamin C among others. While the active ingredients contained in Lingonberry are Quercetin, Resveratrol, Hyperoside, Caffeic Acid, Vitamin C and others.

Lycopene can manipulate biochemical pathways NFKB Signaling, Microtubule Dynamics and Growth Factor Signaling. Vitamin C has biological action on biochemical pathways Cell Cycle, MYC Signaling and WNT Beta Catenin Signaling.

Quercetin can manipulate biochemical pathways Oxidative Stress. Resveratrol has biological action on biochemical pathways P53 Signaling, DNA Repair and Oxidative Stress. And so on.

When treating Protoplasmic Astrocytoma with chemotherapy Temozolomide – Foods like Persimmon are recommended compared to Lingonberry. This is because the active ingredients Quercetin and Resveratrol in Lingonberry interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Lycopene and Vitamin C contained in Persimmon support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: PERSIMMON IS RECOMMENDED OVER LINGONBERRY FOR PROTOPLASMIC ASTROCYTOMA ON TREATMENT WITH CHEMOTHERAPY TEMOZOLOMIDE FOR SOME CONDITIONS.

Eat more nuts, Pine Nut or Acorn?

Nuts are an important part of many diets. The active ingredients contained in Pine Nut are Vitamin E, Beta-sitosterol, Oleic Acid, Linolenic Acid, Linoleic Acid among others. While the active ingredients contained in Acorn are Quercetin, Vitamin C, Beta-sitosterol, Gallic Acid, Beta-carotene and others.

Beta-sitosterol can manipulate biochemical pathways NFKB Signaling, Microtubule Dynamics and Cell Cycle. Vitamin K has biological action on biochemical pathways MYC Signaling, PI3K-AKT-MTOR Signaling and NFKB Signaling.

Quercetin can manipulate biochemical pathways Oxidative Stress. Gallic Acid has biological action on biochemical pathways Oxidative Stress. And so on.

When treating Protoplasmic Astrocytoma with chemotherapy Temozolomide – Foods like Pine Nut are recommended compared to Acorn. This is because the active ingredients Quercetin and Gallic Acid in Acorn interferes with treatment action by canceling out the biochemical pathways through which the chemotherapy works. While the active ingredients Beta-sitosterol and Vitamin K contained in Pine Nut support the treatment action by enhancing the biochemical pathway effect through which the chemotherapy works.

RECOMMENDATION: PINE NUT IS RECOMMENDED OVER ACORN FOR PROTOPLASMIC ASTROCYTOMA ON TREATMENT WITH CHEMOTHERAPY TEMOZOLOMIDE FOR SOME CONDITIONS.

Foods for Genetic Risk of Protoplasmic Astrocytoma

One of the ways to assess risk of cancer is by checking for presence of genetic abnormalities in a set of genes. There is prior information on a list of genes whose mutations and other aberrations can play a role in risk to different cancers. FOXO3 and IDH1 are two genes whose abnormalities are risk factors for Protoplasmic Astrocytoma. In such a cancer risk situation – while there are typically no treatments which a physician can prescribe – the various biochemical pathways which are potentially molecular drivers of Protoplasmic Astrocytoma can be used as a guide for coming up with a recommended personalized nutrition plan. For Protoplasmic Astrocytoma gene FOXO3 has causative impact on biological pathways like MAPK Signaling and Autophagy. And IDH1 has a causative impact on biological pathways like Oncogenic Cancer Epigenetics, Glutathione Metabolism and Hypoxia. Foods and nutritional supplements which have molecular action to cancel out biochemical pathways effects of genes like FOXO3 and IDH1 should be included in a personalized nutrition plan. And those foods and supplements which promote the effects of genes FOXO3 and IDH1 should be avoided.

Eat more pulses, Scarlet Bean or Common Bean?

The active ingredients contained in Scarlet Bean are Vitamin C, Beta-sitosterol, Oleic Acid, Linolenic Acid, Stigmasterol among others. While the active ingredients contained in Common Bean are Apigenin, Esculin, Vitamin C, Oleic Acid, Linolenic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, MYC Signaling and Cell Cycle Checkpoints. Beta-sitosterol has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics and Hypoxia.

Pelargonidin can manipulate biochemical pathways MYC Signaling, Cell Cycle Checkpoints and PI3K-AKT-MTOR Signaling. Linoleic Acid has biological action on biochemical pathways FOXO Signaling. And so on.

For genetic risk of Protoplasmic Astrocytoma due to abnormalities in genes FOXO3 and IDH1 – Foods like Scarlet Bean are recommended compared to Common Bean. This is because the active ingredients Pelargonidin and Linoleic Acid in Common Bean further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Scarlet Bean together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: SCARLET BEAN IS RECOMMENDED OVER COMMON BEAN FOR REDUCING THE GENETIC RISK OF PROTOPLASMIC ASTROCYTOMA DUE TO GENES FOXO3 AND IDH1

Eat more vegetables, Cassava or Chayote?

The active ingredients contained in Cassava are Vitamin C, Beta-sitosterol, Oleic Acid, Linolenic Acid, Linoleic Acid among others. While the active ingredients contained in Chayote are Vitamin C, Oleic Acid, Linolenic Acid, Linoleic Acid, Folic Acid and others.

Vitamin C can manipulate biochemical pathways Apoptosis, MYC Signaling and Cell Cycle Checkpoints. Beta-sitosterol has biological action on biochemical pathways PI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics and Hypoxia.

Linoleic Acid can manipulate biochemical pathways FOXO Signaling. Folic Acid has biological action on biochemical pathways MYC Signaling, Cell Cycle Checkpoints and Apoptosis. And so on.

For genetic risk of Protoplasmic Astrocytoma due to abnormalities in genes FOXO3 and IDH1 – Foods like Cassava are recommended compared to Chayote. This is because the active ingredients Linoleic Acid and Folic Acid in Chayote further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Beta-sitosterol contained in Cassava together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: CASSAVA IS RECOMMENDED OVER CHAYOTE FOR REDUCING THE GENETIC RISK OF PROTOPLASMIC ASTROCYTOMA DUE TO GENES FOXO3 AND IDH1

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Eat more fruits, Feijoa or Peach?

The active ingredients contained in Feijoa are Vitamin C, Lycopene, Casuarinin, Folic Acid among others. While the active ingredients contained in Peach are Vitamin C, Beta-sitosterol, Oleic Acid, Linolenic Acid, Epicatechin and others.

Vitamin C can manipulate biochemical pathways Apoptosis, MYC Signaling and Cell Cycle Checkpoints. Lycopene has biological action on biochemical pathways FOXO Signaling, PI3K-AKT-MTOR Signaling and Hypoxia.

Fisetin can manipulate biochemical pathways MYC Signaling. Linoleic Acid has biological action on biochemical pathways FOXO Signaling. And so on.

For genetic risk of Protoplasmic Astrocytoma due to abnormalities in genes FOXO3 and IDH1 – Foods like Feijoa are recommended compared to Peach. This is because the active ingredients Fisetin and Linoleic Acid in Peach further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin C and Lycopene contained in Feijoa together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: FEIJOA IS RECOMMENDED OVER PEACH FOR REDUCING THE GENETIC RISK OF PROTOPLASMIC ASTROCYTOMA DUE TO GENES FOXO3 AND IDH1

Eat more nuts, Hazelnut or Peanut?

The active ingredients contained in Hazelnut are Vitamin E, Quercetin, Oleic Acid, Linolenic Acid, Linoleic Acid among others. While the active ingredients contained in Peanut are Vitamin C, Vitamin E, Beta-sitosterol, Quercetin, Oleic Acid and others.

Vitamin E can manipulate biochemical pathways Apoptosis, MYC Signaling and Cell Cycle Checkpoints. Myricitrin has biological action on biochemical pathways PI3K-AKT-MTOR Signaling and MYC Signaling.

Lecithin can manipulate biochemical pathways MYC Signaling and PI3K-AKT-MTOR Signaling. Linoleic Acid has biological action on biochemical pathways FOXO Signaling. And so on.

For genetic risk of Protoplasmic Astrocytoma due to abnormalities in genes FOXO3 and IDH1 – Foods like Hazelnut are recommended compared to Peanut. This is because the active ingredients Lecithin and Linoleic Acid in Peanut further promote the effects of genes on the biochemical pathways. While the active ingredients Vitamin E and Myricitrin contained in Hazelnut together have a canceling effect of genes on the biochemical pathways.

RECOMMENDATION: HAZELNUT IS RECOMMENDED OVER PEANUT FOR REDUCING THE GENETIC RISK OF PROTOPLASMIC ASTROCYTOMA DUE TO GENES FOXO3 AND IDH1


In Summary

An important thing to remember is that cancer treatments may not be the same for everyone – and neither should your nutrition be. Nutrition which includes food and nutritional supplements is a very effective tool controlled by you.

“What should I eat?” is the most frequently asked question in the context of cancer. The answer calculation is complex and depends upon cancer type, underlying genomics, current treatments, any allergies, lifestyle information, and factors like BMI.

The addon personalized nutrition plan recommends foods and supplements which minimizes adverse nutrition interactions and encourages support to treatments.

You can get started NOW and design a personalized nutrition plan for Protoplasmic Astrocytoma by answering questions on type of cancer, current treatments, supplements, allergies, age group, gender, and lifestyle information.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

sample-report


References

Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


Scientifically Reviewed by: Dr. Cogle

Christopher R. Cogle, M.D. is a tenured professor at the University of Florida, Chief Medical Officer of Florida Medicaid, and Director of the Florida Health Policy Leadership Academy at the Bob Graham Center for Public Service.

You can also read this in

How useful was this post?

Click on a star to rate it!

Average rating 4.7 / 5. Vote count: 24

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?