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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

For which cancer is Sparkleberry beneficial for?

May 1, 2022

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Highlights

Nutrition is the single most effective tool which cancer patients can control for managing cancers like Metastatic Squamous Neck Cancer with Occult Primary or Basal Cell Carcinoma – hence it is important to identify those Foods and Supplements which are scientifically recommended for you. A frequently asked question is if foods like Sparkleberry are beneficial for cancer and along with which treatments? There is a mis-conception that all plant-based foods are good for all cancers and all of them are equal in terms of their benefits or their lack of. The reality is that some plant-based foods will be better than others for a specific type of cancer, treatments and other conditions. So Sparkleberry benefits will vary and the answer is contextual.

For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made.

So are there types of cancer where Sparkleberry has more benefits? Yes! Sparkleberry is beneficial for Basal Cell Carcinoma patients taking Vismodegib treatment. But has adverse interactions for Metastatic Squamous Neck Cancer with Occult Primary patients on Ifosfamide treatment.

For Basal Cell Carcinoma along with Vismodegib – biochemical pathways like Nutrient sensing (AMPK Signaling), Vitamin D Signaling, Cell Cycle (Proliferation), Oncogenic Cancer Epigenetics (HDAC Class 1 Signaling) and G-protein-coupled Receptor Signaling (cAMP Signaling) are potential drivers of the disease. Sparkleberry has active ingredients which can manipulate these biochemical pathways to reduce the disease drivers and hence are scientifically beneficial. But for Metastatic Squamous Neck Cancer with Occult Primary along with Ifosfamide – biochemical pathways like DNA Repair (Homology Directed Repair), Hippo Signaling, Cell Cycle (Proliferation), DNA Repair (Global Genome Nucleotide Excision Repair) and P53 Signaling are potential drivers of the disease. Sparkleberry has active ingredients which can increase disease drivers like DNA Repair (Homology Directed Repair), Hippo Signaling, Cell Cycle (Proliferation), DNA Repair (Global Genome Nucleotide Excision Repair) and P53 Signaling and hence intake should be reduced.

Similarly, eating Sparkleberry can have scientific benefits for healthy individuals who have a gene mutation in KRAS which suggests potential risk of cancer. This is because of biochemical pathways PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), Angiogenesis, Stem Cell Signaling, Insulin Signaling and MYC Signaling. But reduce intake of Sparkleberry when at genetic risk of cancer due to mutation of gene CDH1 due to its manipulation of biochemical pathways Estrogen Signaling, Adherens junction (CDH1 Signaling), Stem Cell Signaling, WNT Betacatenin Signaling and Epithelial to Mesenchymal Transition causing cancer drivers to increase.

The takeaway being – for Metastatic Squamous Neck Cancer with Occult Primary, Basal Cell Carcinoma and other cancers individual conditions can influence if foods like Sparkleberry are recommended or not. As conditions like ongoing treatments, supplements, habits and other conditions change; the nutrition plan must be re-designed and personalized. Whether Metastatic Squamous Neck Cancer with Occult Primary or Basal Cell Carcinoma or other cancer types -, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are also key decision factors for creating a personalized nutrition plan.



Why is the choice of foods important for cancer?

Foods like Sparkleberry typically contain more than one active ingredient at varying concentrations. Each of these active ingredients like Resveratrol has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for Metastatic Squamous Neck Cancer with Occult Primary, Basal Cell Carcinoma and other cancers there is a need to personalize which foods and supplements to take and regularly evaluate if foods like Sparkleberry are recommended or not.

Sparkleberry for Basal Cell Carcinoma taking Vismodegib Sparkleberry for Metastatic Squamous Neck Cancer with Occult Primary with Ifosfamide treatment

So some of the example questions one may have related to Sparkleberry can be: Is Sparkleberry beneficial for me? Should I eat it when at genetic cancer risk due to mutation of gene CDH1? Should I eat Sparkleberry when a mutation of a gene KRAS is identified? Should I eat Sparkleberry when diagnosed with Metastatic Squamous Neck Cancer with Occult Primary? Should I eat Sparkleberry when diagnosed with Basal Cell Carcinoma? Should I eat Sparkleberry when on Ifosfamide treatment? Should I continue eating Sparkleberry if my treatment changes from Ifosfamide to Vismodegib? Are the implications of taking Sparkleberry in Basal Cell Carcinoma the same as Metastatic Squamous Neck Cancer with Occult Primary? And so on.

Sparkleberry and cancer

Vaccinium arboreum (sparkleberry or farkleberry) is a species of Vaccinium native to the southeastern and south-central United States, from southern Virginia west to southeastern Nebraska, south to Florida and eastern Texas, and north to Illinois.

Sparkleberry contains many active ingredients like Resveratrol and many other Bioactives at different concentrations. The molecular pathways which are regulated by Sparkleberry include DNA Repair (Homology Directed Repair), Hippo Signaling, Nutrient sensing (AMPK Signaling), Vitamin D Signaling, Estrogen Signaling and many others. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Sparkleberry and supplements is an important decision to be made. And not necessarily the same food choices are scientifically best for all individuals.

Include Sparkleberry in my nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is dependent on multiple factors. Just like the same treatment does not work for every cancer patient, based on individual context the Sparkleberry may have scientific benefits or have adverse interactions. Along with which cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Any benefits of Sparkleberry for Metastatic Squamous Neck Cancer with Occult Primary with Ifosfamide treatment?

Metastatic Squamous Neck Cancer with Occult Primary is known to have mutations in gene like TP53, COL1A1 and COL2A1 and others which together cause biochemical pathway changes in DNA Repair (Homology Directed Repair), Hippo Signaling, Cell Cycle (Proliferation), DNA Repair (Global Genome Nucleotide Excision Repair) and P53 Signaling. A cancer treatment like Ifosfamide has molecular action on a unique set of biochemical pathways . The treatment intent is to have a good overlap with the cancer driving pathways and reduce the disease drivers. In such conditions foods which can scientifically cancel out the treatment effect by reducing the overlap between the cancer driving pathways and treatment are candidates for reducing intake of or completely avoid. For example – in the case of Metastatic Squamous Neck Cancer with Occult Primary and treatment Ifosfamide – Sparkleberry is not recommended. Sparkleberry impacts pathways or processes like DNA Repair (Homology Directed Repair) and Hippo Signaling which can negate the effects of the treatment.

2. Any benefits of Sparkleberry for Basal Cell Carcinoma with Vismodegib treatment?

Basal Cell Carcinoma is defined and driven by specific genetic mutations like PTCH1, CSMD3 and CSMD1 leading to biochemical pathway changes in Nutrient sensing (AMPK Signaling), Vitamin D Signaling, Cell Cycle (Proliferation), Oncogenic Cancer Epigenetics (HDAC Class 1 Signaling) and G-protein-coupled Receptor Signaling (cAMP Signaling). Also treatments like Vismodegib have molecular action on a unique set of biochemical pathways. Sparkleberry should be considered for Basal Cell Carcinoma while on Vismodegib treatment. Sparkleberry impacts pathways or processes like Nutrient sensing (AMPK Signaling) and Vitamin D Signaling which can either reduce drivers of Basal Cell Carcinoma and/or improve Vismodegib treatment effect.

For Which Cancer Is Sparkleberry Beneficial For?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Any benefits of Sparkleberry for gene CDH1 associated cancer genetic risk?

Many companies offer gene panel tests for evaluating genetic risk to different cancers. These panels cover genes like CDH1 and many others associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. The intent of the genetic testing of CDH1 is for diagnosis and/or to find out any potential risk factors for cancer. CDH1 mutation causes biochemical pathways or processes like Estrogen Signaling, Adherens junction (CDH1 Signaling), Stem Cell Signaling, WNT Betacatenin Signaling and Epithelial to Mesenchymal Transition to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like Estrogen Signaling, Adherens junction (CDH1 Signaling), Stem Cell Signaling, WNT Betacatenin Signaling and Epithelial to Mesenchymal Transition. Intake of foods like Sparkleberry should be reduced when there is a mutation of CDH1 for risk of Gastric cancer and Breast cancer. Sparkleberry impacts pathways or processes like Estrogen Signaling and creates adverse effects with CDH1 mutation.

4. Any benefits of Sparkleberry for gene KRAS associated cancer genetic risk?

KRAS is also one of many genes available in panels for cancer risk testing. KRAS mutation causes biochemical pathways or processes like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), Angiogenesis, Stem Cell Signaling, Insulin Signaling and MYC Signaling to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), Angiogenesis, Stem Cell Signaling, Insulin Signaling and MYC Signaling. Intake of foods like Sparkleberry should be considered when Lung Cancer, Acute Lymphoid Leukemia and Ampullary Carcinoma risk is identified due to gene KRAS mutation. Sparkleberry impacts biochemical pathways or processes like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling) and Angiogenesis associated with genetic risk to KRAS mutation.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Personalized nutrition planning for cancer can inform if foods like Sparkleberry are recommended or not. Nutrition is the single most effective tool which cancer patients can control and nutrition decisions are dependent on questions like “Is Sparkleberry beneficial for me?”

The addon personalized nutrition planning for cancer is a software approach based on molecular science. The addon approach supports cancers like Metastatic Squamous Neck Cancer with Occult Primary, Basal Cell Carcinoma and others along with commonly reported genomic group clusters.

To get your personalized nutrition plan – enter details like cancer indication (example Metastatic Squamous Neck Cancer with Occult Primary, name of current cancer and non-cancer treatments; habits and lifestyle conditions.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

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Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


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