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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

For which cancer is Burdock beneficial for?

Apr 22, 2022

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Highlights

Nutrition is the single most effective tool which cancer patients can control for managing cancers like Ameloblastoma or Monoclonal gammopathy of undetermined significance – hence it is important to identify those Foods and Supplements which are scientifically recommended for you. A frequently asked question is if foods like Burdock are beneficial for cancer and along with which treatments? There is a mis-conception that all plant-based foods are good for all cancers and all of them are equal in terms of their benefits or their lack of. The reality is that some plant-based foods will be better than others for a specific type of cancer, treatments and other conditions. So Burdock benefits will vary and the answer is contextual.

For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made.

So are there types of cancer where Burdock has more benefits? Yes! Burdock is beneficial for Monoclonal gammopathy of undetermined significance patients taking Lenalidomide treatment. But has adverse interactions for Ameloblastoma patients on Radiation treatment.

For Monoclonal gammopathy of undetermined significance along with Lenalidomide – biochemical pathways like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), NFKB Signaling, Hypoxia (HIF1 Signaling), P53 Signaling and WNT Betacatenin Signaling are potential drivers of the disease. Burdock has active ingredients which can manipulate these biochemical pathways to reduce the disease drivers and hence are scientifically beneficial. But for Ameloblastoma along with Radiation – biochemical pathways like Epithelial to Mesenchymal Transition, Cell Cycle (Proliferation), RAS-RAF Signaling (RAS Signaling), MYC Signaling and PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling) are potential drivers of the disease. Burdock has active ingredients which can increase disease drivers like Epithelial to Mesenchymal Transition, Cell Cycle (Proliferation), RAS-RAF Signaling (RAS Signaling), MYC Signaling and PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling) and hence intake should be reduced.

Similarly, eating Burdock can have scientific benefits for healthy individuals who have a gene mutation in SMAD4 which suggests potential risk of cancer. This is because of biochemical pathways Lipid Metabolism (Arachidonic Acid Metabolism), MAPK Signaling, Stem Cell Signaling, Growth Factor Signaling (EGFR Signaling) and MYC Signaling. But reduce intake of Burdock when at genetic risk of cancer due to mutation of gene CREBBP due to its manipulation of biochemical pathways Histone/Protein Acetylation causing cancer drivers to increase.

The takeaway being – for Ameloblastoma, Monoclonal gammopathy of undetermined significance and other cancers individual conditions can influence if foods like Burdock are recommended or not. As conditions like ongoing treatments, supplements, habits and other conditions change; the nutrition plan must be re-designed and personalized. Whether Ameloblastoma or Monoclonal gammopathy of undetermined significance or other cancer types -, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are also key decision factors for creating a personalized nutrition plan.



Why is the choice of foods important for cancer?

Foods like Burdock typically contain more than one active ingredient at varying concentrations. Each of these active ingredients like Oleic Acid has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for Ameloblastoma, Monoclonal gammopathy of undetermined significance and other cancers there is a need to personalize which foods and supplements to take and regularly evaluate if foods like Burdock are recommended or not.

Burdock for Monoclonal gammopathy of undetermined significance taking Lenalidomide Burdock for Ameloblastoma with Radiation treatment

So some of the example questions one may have related to Burdock can be: Is Burdock beneficial for me? Should I eat it when at genetic cancer risk due to mutation of gene CREBBP? Should I eat Burdock when a mutation of a gene SMAD4 is identified? Should I eat Burdock when diagnosed with Ameloblastoma? Should I eat Burdock when diagnosed with Monoclonal gammopathy of undetermined significance? Should I eat Burdock when on Radiation treatment? Should I continue eating Burdock if my treatment changes from Radiation to Lenalidomide? Are the implications of taking Burdock in Monoclonal gammopathy of undetermined significance the same as Ameloblastoma? And so on.

Burdock and cancer

Burdock is a plant that is found all over the world. Burdock root is sometimes used as food. The root, leaf, and seed are used as medicine. Burdock is used for skin problems, stomach problems, joint swelling, and other conditions, but there is no good evidence to support its use for any condition. Burdock contains chemicals that might have activity against bacteria and inflammation.

Burdock contains many active ingredients like Oleic Acid, Chlorogenic Acid, Linolenic Acid, Arctigenin, Caffeic Acid and many other Bioactives at different concentrations. The molecular pathways which are regulated by Burdock include Epithelial to Mesenchymal Transition, PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), NFKB Signaling, Histone/Protein Acetylation, Lipid Metabolism (Arachidonic Acid Metabolism) and many others. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Burdock and supplements is an important decision to be made. And not necessarily the same food choices are scientifically best for all individuals.

Include Burdock in my nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is dependent on multiple factors. Just like the same treatment does not work for every cancer patient, based on individual context the Burdock may have scientific benefits or have adverse interactions. Along with which cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Any benefits of Burdock for Ameloblastoma with Radiation treatment?

Ameloblastoma is known to have mutations in gene like BRAF, SMO and PIK3CA and others which together cause biochemical pathway changes in Epithelial to Mesenchymal Transition, Cell Cycle (Proliferation), RAS-RAF Signaling (RAS Signaling), MYC Signaling and PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling). A cancer treatment like Radiation has molecular action on a unique set of biochemical pathways . The treatment intent is to have a good overlap with the cancer driving pathways and reduce the disease drivers. In such conditions foods which can scientifically cancel out the treatment effect by reducing the overlap between the cancer driving pathways and treatment are candidates for reducing intake of or completely avoid. For example – in the case of Ameloblastoma and treatment Radiation – Burdock is not recommended. Burdock impacts pathways or processes like Epithelial to Mesenchymal Transition which can negate the effects of the treatment.

2. Any benefits of Burdock for Monoclonal gammopathy of undetermined significance with Lenalidomide treatment?

Monoclonal gammopathy of undetermined significance is defined and driven by specific genetic mutations like LATS2, ZMYM2 and CDK8 leading to biochemical pathway changes in PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), NFKB Signaling, Hypoxia (HIF1 Signaling), P53 Signaling and WNT Betacatenin Signaling. Also treatments like Lenalidomide have molecular action on a unique set of biochemical pathways. Burdock should be considered for Monoclonal gammopathy of undetermined significance while on Lenalidomide treatment. Burdock impacts pathways or processes like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling) and NFKB Signaling which can either reduce drivers of Monoclonal gammopathy of undetermined significance and/or improve Lenalidomide treatment effect.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Any benefits of Burdock for gene CREBBP associated cancer genetic risk?

Many companies offer gene panel tests for evaluating genetic risk to different cancers. These panels cover genes like CREBBP and many others associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. The intent of the genetic testing of CREBBP is for diagnosis and/or to find out any potential risk factors for cancer. CREBBP mutation causes biochemical pathways or processes like Histone/Protein Acetylation to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like Histone/Protein Acetylation. Intake of foods like Burdock should be reduced when there is a mutation of CREBBP for risk of Follicular Lymphoma and Non-Hodgkin Lymphoma. Burdock impacts pathways or processes like Histone/Protein Acetylation and creates adverse effects with CREBBP mutation.

4. Any benefits of Burdock for gene SMAD4 associated cancer genetic risk?

SMAD4 is also one of many genes available in panels for cancer risk testing. SMAD4 mutation causes biochemical pathways or processes like Lipid Metabolism (Arachidonic Acid Metabolism), MAPK Signaling, Stem Cell Signaling, Growth Factor Signaling (EGFR Signaling) and MYC Signaling to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like Lipid Metabolism (Arachidonic Acid Metabolism), MAPK Signaling, Stem Cell Signaling, Growth Factor Signaling (EGFR Signaling) and MYC Signaling. Intake of foods like Burdock should be considered when Colon cancer and Gallbladder Cancer risk is identified due to gene SMAD4 mutation. Burdock impacts biochemical pathways or processes like Lipid Metabolism (Arachidonic Acid Metabolism) and MAPK Signaling associated with genetic risk to SMAD4 mutation.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Personalized nutrition planning for cancer can inform if foods like Burdock are recommended or not. Nutrition is the single most effective tool which cancer patients can control and nutrition decisions are dependent on questions like “Is Burdock beneficial for me?”

The addon personalized nutrition planning for cancer is a software approach based on molecular science. The addon approach supports cancers like Ameloblastoma, Monoclonal gammopathy of undetermined significance and others along with commonly reported genomic group clusters.

To get your personalized nutrition plan – enter details like cancer indication (example Ameloblastoma, name of current cancer and non-cancer treatments; habits and lifestyle conditions.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

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Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


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