addonfinal2

What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

For which cancer is Angelica beneficial for?

Apr 13, 2022

0
(0)
Estimated reading time: 8 minutes
Home » Blogs » For which cancer is Angelica beneficial for?

Highlights

Nutrition is the single most effective tool which cancer patients can control for managing cancers like Myeloproliferative Neoplasms or ALK+ Non-Small Cell Lung Cancer – hence it is important to identify those Foods and Supplements which are scientifically recommended for you. A frequently asked question is if foods like Angelica are beneficial for cancer and along with which treatments? There is a mis-conception that all plant-based foods are good for all cancers and all of them are equal in terms of their benefits or their lack of. The reality is that some plant-based foods will be better than others for a specific type of cancer, treatments and other conditions. So Angelica benefits will vary and the answer is contextual.

For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made.

So are there types of cancer where Angelica has more benefits? Yes! Angelica is beneficial for ALK+ Non-Small Cell Lung Cancer patients taking Brigatinib treatment. But has adverse interactions for Myeloproliferative Neoplasms patients on Decitabine treatment.

For ALK+ Non-Small Cell Lung Cancer along with Brigatinib – biochemical pathways like MAPK Signaling, PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), Extracellular Matrix Remodelling (Syndecan Signaling), Growth Factor Signaling (KIT Signaling) and RAS-RAF Signaling (RAS Signaling) are potential drivers of the disease. Angelica has active ingredients which can manipulate these biochemical pathways to reduce the disease drivers and hence are scientifically beneficial. But for Myeloproliferative Neoplasms along with Decitabine – biochemical pathways like Adherens junction, Hypoxia (HIF1 Signaling), Apoptosis (Intrinsic Apoptosis), Oncogenic Histone Methylation (Histone 3 Lysine 36 Methylation) and MYC Signaling are potential drivers of the disease. Angelica has active ingredients which can increase disease drivers like Adherens junction, Hypoxia (HIF1 Signaling), Apoptosis (Intrinsic Apoptosis), Oncogenic Histone Methylation (Histone 3 Lysine 36 Methylation) and MYC Signaling and hence intake should be reduced.

Similarly, eating Angelica can have scientific benefits for healthy individuals who have a gene mutation in MLH1 which suggests potential risk of cancer. This is because of biochemical pathways P53 Signaling, Angiogenesis, Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (EGFR Signaling). But reduce intake of Angelica when at genetic risk of cancer due to mutation of gene NPM1 due to its manipulation of biochemical pathways MYC Signaling and Stem Cell Signaling causing cancer drivers to increase.

The takeaway being – for Myeloproliferative Neoplasms, ALK+ Non-Small Cell Lung Cancer and other cancers individual conditions can influence if foods like Angelica are recommended or not. As conditions like ongoing treatments, supplements, habits and other conditions change; the nutrition plan must be re-designed and personalized. Whether Myeloproliferative Neoplasms or ALK+ Non-Small Cell Lung Cancer or other cancer types -, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are also key decision factors for creating a personalized nutrition plan.



Why is the choice of foods important for cancer?

Foods like Angelica typically contain more than one active ingredient at varying concentrations. Each of these active ingredients like Angelicin has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for Myeloproliferative Neoplasms, ALK+ Non-Small Cell Lung Cancer and other cancers there is a need to personalize which foods and supplements to take and regularly evaluate if foods like Angelica are recommended or not.

Angelica for ALK+ Non-Small Cell Lung Cancer taking Brigatinib Angelica for Myeloproliferative Neoplasms with Decitabine treatment

So some of the example questions one may have related to Angelica can be: Is Angelica beneficial for me? Should I eat it when at genetic cancer risk due to mutation of gene NPM1? Should I eat Angelica when a mutation of a gene MLH1 is identified? Should I eat Angelica when diagnosed with Myeloproliferative Neoplasms? Should I eat Angelica when diagnosed with ALK+ Non-Small Cell Lung Cancer? Should I eat Angelica when on Decitabine treatment? Should I continue eating Angelica if my treatment changes from Decitabine to Brigatinib? Are the implications of taking Angelica in ALK+ Non-Small Cell Lung Cancer the same as Myeloproliferative Neoplasms? And so on.

Angelica and cancer

Angelica is a genus of plants and herbs that’s often used in traditional medicine, particularly in Asian countries. The roots of many species of Angelica are used to make herbal medicines.

They also tend to have a strong, unique smell due to the aromatic compounds they contain. The scent is often described as musky, earthy, or herbaceous. Following are some of potential health benefits:- 

Angelica contains many active ingredients like Angelicin, Luteolin, Quercetin, Umbelliferone and many other Bioactives at different concentrations. The molecular pathways which are regulated by Angelica include Adherens junction, MAPK Signaling, PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), MYC Signaling, Stem Cell Signaling and many others. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Angelica and supplements is an important decision to be made. And not necessarily the same food choices are scientifically best for all individuals.

Include Angelica in my nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is dependent on multiple factors. Just like the same treatment does not work for every cancer patient, based on individual context the Angelica may have scientific benefits or have adverse interactions. Along with which cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Any benefits of Angelica for Myeloproliferative Neoplasms with Decitabine treatment?

Myeloproliferative Neoplasms is known to have mutations in gene like JAK2, CALR and TET2 and others which together cause biochemical pathway changes in Adherens junction, Hypoxia (HIF1 Signaling), Apoptosis (Intrinsic Apoptosis), Oncogenic Histone Methylation (Histone 3 Lysine 36 Methylation) and MYC Signaling. A cancer treatment like Decitabine has molecular action on a unique set of biochemical pathways . The treatment intent is to have a good overlap with the cancer driving pathways and reduce the disease drivers. In such conditions foods which can scientifically cancel out the treatment effect by reducing the overlap between the cancer driving pathways and treatment are candidates for reducing intake of or completely avoid. For example – in the case of Myeloproliferative Neoplasms and treatment Decitabine – Angelica is not recommended. Angelica impacts pathways or processes like Adherens junction which can negate the effects of the treatment.

2. Any benefits of Angelica for ALK+ Non-Small Cell Lung Cancer with Brigatinib treatment?

ALK+ Non-Small Cell Lung Cancer is defined and driven by specific genetic mutations like ALK, TP53 and CSMD3 leading to biochemical pathway changes in MAPK Signaling, PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), Extracellular Matrix Remodelling (Syndecan Signaling), Growth Factor Signaling (KIT Signaling) and RAS-RAF Signaling (RAS Signaling). Also treatments like Brigatinib have molecular action on a unique set of biochemical pathways. Angelica should be considered for ALK+ Non-Small Cell Lung Cancer while on Brigatinib treatment. Angelica impacts pathways or processes like MAPK Signaling and PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling) which can either reduce drivers of ALK+ Non-Small Cell Lung Cancer and/or improve Brigatinib treatment effect.

For Which Cancer Is Angelica Beneficial For?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Any benefits of Angelica for gene NPM1 associated cancer genetic risk?

Many companies offer gene panel tests for evaluating genetic risk to different cancers. These panels cover genes like NPM1 and many others associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. The intent of the genetic testing of NPM1 is for diagnosis and/or to find out any potential risk factors for cancer. NPM1 mutation causes biochemical pathways or processes like MYC Signaling and Stem Cell Signaling to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like MYC Signaling and Stem Cell Signaling. Intake of foods like Angelica should be reduced when there is a mutation of NPM1 for risk of Acute Myeloid Leukemia. Angelica impacts pathways or processes like MYC Signaling and Stem Cell Signaling and creates adverse effects with NPM1 mutation.

4. Any benefits of Angelica for gene MLH1 associated cancer genetic risk?

MLH1 is also one of many genes available in panels for cancer risk testing. MLH1 mutation causes biochemical pathways or processes like P53 Signaling, Angiogenesis, Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (EGFR Signaling) to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like P53 Signaling, Angiogenesis, Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (EGFR Signaling). Intake of foods like Angelica should be considered when Colon cancer risk is identified due to gene MLH1 mutation. Angelica impacts biochemical pathways or processes like P53 Signaling and Angiogenesis associated with genetic risk to MLH1 mutation.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Personalized nutrition planning for cancer can inform if foods like Angelica are recommended or not. Nutrition is the single most effective tool which cancer patients can control and nutrition decisions are dependent on questions like “Is Angelica beneficial for me?”

The addon personalized nutrition planning for cancer is a software approach based on molecular science. The addon approach supports cancers like Myeloproliferative Neoplasms, ALK+ Non-Small Cell Lung Cancer and others along with commonly reported genomic group clusters.

To get your personalized nutrition plan – enter details like cancer indication (example Myeloproliferative Neoplasms, name of current cancer and non-cancer treatments; habits and lifestyle conditions.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

sample-report

Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


You can also read this in

How useful was this post?

Click on a star to rate it!

Average rating 0 / 5. Vote count: 0

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?