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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

For which cancer is Black Chokeberry beneficial for?

Apr 4, 2022

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Highlights

Nutrition is the single most effective tool which cancer patients can control for managing cancers like Oligoastrocytoma or Cervical Squamous Cell Carcinoma – hence it is important to identify those Foods and Supplements which are scientifically recommended for you. A frequently asked question is if foods like Black Chokeberry are beneficial for cancer and along with which treatments? There is a mis-conception that all plant-based foods are good for all cancers and all of them are equal in terms of their benefits or their lack of. The reality is that some plant-based foods will be better than others for a specific type of cancer, treatments and other conditions. So Black Chokeberry benefits will vary and the answer is contextual.

For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made.

So are there types of cancer where Black Chokeberry has more benefits? Yes! Black Chokeberry is beneficial for Cervical Squamous Cell Carcinoma patients taking Bevacizumab treatment. But has adverse interactions for Oligoastrocytoma patients on Procarbazine treatment.

For Cervical Squamous Cell Carcinoma along with Bevacizumab – biochemical pathways like Angiogenesis, Extracellular Matrix Remodelling (Collagen Degradation), Cytoskeletal Dynamics (CDC42 Signaling), Chemokine Signaling (IL8 Signaling) and Oncogenic Cancer Epigenetics (HDAC Class 1 Signaling) are potential drivers of the disease. Black Chokeberry has active ingredients which can manipulate these biochemical pathways to reduce the disease drivers and hence are scientifically beneficial. But for Oligoastrocytoma along with Procarbazine – biochemical pathways like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), DNA Repair (Homology Directed Repair), Notch Signaling (NOTCH1 Signaling), DNA Repair (DNA Damage Response Signaling) and MAPK Signaling (ERK Signaling) are potential drivers of the disease. Black Chokeberry has active ingredients which can increase disease drivers like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), DNA Repair (Homology Directed Repair), Notch Signaling (NOTCH1 Signaling), DNA Repair (DNA Damage Response Signaling) and MAPK Signaling (ERK Signaling) and hence intake should be reduced.

Similarly, eating Black Chokeberry can have scientific benefits for healthy individuals who have a gene mutation in MLH1 which suggests potential risk of cancer. This is because of biochemical pathways P53 Signaling, Lipid Metabolism (Arachidonic Acid Metabolism), Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (EGFR Signaling).

The takeaway being – for Oligoastrocytoma, Cervical Squamous Cell Carcinoma and other cancers individual conditions can influence if foods like Black Chokeberry are recommended or not. As conditions like ongoing treatments, supplements, habits and other conditions change; the nutrition plan must be re-designed and personalized. Whether Oligoastrocytoma or Cervical Squamous Cell Carcinoma or other cancer types -, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are also key decision factors for creating a personalized nutrition plan.



Why is the choice of foods important for cancer?

Foods like Black Chokeberry typically contain more than one active ingredient at varying concentrations. Each of these active ingredients like Caffeic Acid has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for Oligoastrocytoma, Cervical Squamous Cell Carcinoma and other cancers there is a need to personalize which foods and supplements to take and regularly evaluate if foods like Black Chokeberry are recommended or not.

Black chokeberry for Cervical Squamous Cell Carcinoma taking Bevacizumab treatment and black chokeberry for  Oligoastrocytoma along with Procarbazine treatment

So some of the example questions one may have related to Black Chokeberry can be: Is Black Chokeberry beneficial for me?Should I eat Black Chokeberry when a mutation of a gene MLH1 is identified? Should I eat Black Chokeberry when diagnosed with Oligoastrocytoma? Should I eat Black Chokeberry when diagnosed with Cervical Squamous Cell Carcinoma? Should I eat Black Chokeberry when on Procarbazine treatment? Should I continue eating Black Chokeberry if my treatment changes from Procarbazine to Bevacizumab? Are the implications of taking Black Chokeberry in Cervical Squamous Cell Carcinoma the same as Oligoastrocytoma? And so on.

Black Chokeberry and cancer

Black Chokeberry (Aronia Melanocarpa) is small shrub with black-coloured fruits, native to North America. They are high in anthocyanins and have strong antioxidant properties. Following are some of the potential health benefits of Black chokeberries :

Black Chokeberry contains many active ingredients like Caffeic Acid, Quercetin, Oleic Acid, Hyperoside, Isoquercitrin and many other Bioactives at different concentrations. The molecular pathways which are regulated by Black Chokeberry include PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), Angiogenesis, Extracellular Matrix Remodelling (Collagen Degradation), Oncogenic Cancer Epigenetics (CpG Methylation), P53 Signaling and many others. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Black Chokeberry and supplements is an important decision to be made. And not necessarily the same food choices are scientifically best for all individuals.

Include Black Chokeberry in my nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is dependent on multiple factors. Just like the same treatment does not work for every cancer patient, based on individual context the Black Chokeberry may have scientific benefits or have adverse interactions. Along with which cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Any benefits of Black Chokeberry for Oligoastrocytoma with Procarbazine treatment?

Oligoastrocytoma is known to have mutations in gene like IDH1, ATRX and TP53 and others which together cause biochemical pathway changes in PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), DNA Repair (Homology Directed Repair), Notch Signaling (NOTCH1 Signaling), DNA Repair (DNA Damage Response Signaling) and MAPK Signaling (ERK Signaling). A cancer treatment like Procarbazine has molecular action on a unique set of biochemical pathways . The treatment intent is to have a good overlap with the cancer driving pathways and reduce the disease drivers. In such conditions foods which can scientifically cancel out the treatment effect by reducing the overlap between the cancer driving pathways and treatment are candidates for reducing intake of or completely avoid. For example – in the case of Oligoastrocytoma and treatment Procarbazine – Black Chokeberry is not recommended. Black Chokeberry impacts pathways or processes like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling) which can negate the effects of the treatment.

2. Any benefits of Black Chokeberry for Cervical Squamous Cell Carcinoma with Bevacizumab treatment?

Cervical Squamous Cell Carcinoma is defined and driven by specific genetic mutations like PIK3CA, MUC4 and KMT2C leading to biochemical pathway changes in Angiogenesis, Extracellular Matrix Remodelling (Collagen Degradation), Cytoskeletal Dynamics (CDC42 Signaling), Chemokine Signaling (IL8 Signaling) and Oncogenic Cancer Epigenetics (HDAC Class 1 Signaling). Also treatments like Bevacizumab have molecular action on a unique set of biochemical pathways. Black Chokeberry should be considered for Cervical Squamous Cell Carcinoma while on Bevacizumab treatment. Black Chokeberry impacts pathways or processes like Angiogenesis and Extracellular Matrix Remodelling (Collagen Degradation) which can either reduce drivers of Cervical Squamous Cell Carcinoma and/or improve Bevacizumab treatment effect.

For Which Cancer Is Black Chokeberry Beneficial For

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Any benefits of Black Chokeberry for gene MLH1 associated cancer genetic risk?

MLH1 is also one of many genes available in panels for cancer risk testing. MLH1 mutation causes biochemical pathways or processes like P53 Signaling, Lipid Metabolism (Arachidonic Acid Metabolism), Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (EGFR Signaling) to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like P53 Signaling, Lipid Metabolism (Arachidonic Acid Metabolism), Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (EGFR Signaling). Intake of foods like Black Chokeberry should be considered when Colon cancer risk is identified due to gene MLH1 mutation. Black Chokeberry impacts biochemical pathways or processes like P53 Signaling and Lipid Metabolism (Arachidonic Acid Metabolism) associated with genetic risk to MLH1 mutation.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Personalized nutrition planning for cancer can inform if foods like Black Chokeberry are recommended or not. Nutrition is the single most effective tool which cancer patients can control and nutrition decisions are dependent on questions like “Is Black Chokeberry beneficial for me?”

The addon personalized nutrition planning for cancer is a software approach based on molecular science. The addon approach supports cancers like Oligoastrocytoma, Cervical Squamous Cell Carcinoma and others along with commonly reported genomic group clusters.

To get your personalized nutrition plan – enter details like cancer indication (example Oligoastrocytoma, name of current cancer and non-cancer treatments; habits and lifestyle conditions.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

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Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


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