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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

For which cancer is Mustard beneficial for?

Mar 30, 2022

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Highlights

Nutrition is the single most effective tool which cancer patients can control for managing cancers like Myeloproliferative Neoplasms or Monoclonal gammopathy of undetermined significance – hence it is important to identify those Foods and Supplements which are scientifically recommended for you. A frequently asked question is if foods like Mustard are beneficial for cancer and along with which treatments? There is a mis-conception that all plant-based foods are good for all cancers and all of them are equal in terms of their benefits or their lack of. The reality is that some plant-based foods will be better than others for a specific type of cancer, treatments and other conditions. So Mustard benefits will vary and the answer is contextual.

For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made.

So are there types of cancer where Mustard has more benefits? Yes! Mustard is beneficial for Monoclonal gammopathy of undetermined significance patients taking Lenalidomide treatment. But has adverse interactions for Myeloproliferative Neoplasms patients on Decitabine treatment.

For Monoclonal gammopathy of undetermined significance along with Lenalidomide – biochemical pathways like P53 Signaling, PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), NFKB Signaling, Hypoxia (HIF1 Signaling) and WNT Betacatenin Signaling are potential drivers of the disease. Mustard has active ingredients which can manipulate these biochemical pathways to reduce the disease drivers and hence are scientifically beneficial. But for Myeloproliferative Neoplasms along with Decitabine – biochemical pathways like Oncogenic Cancer Epigenetics (CpG Methylation), Oncogenic Histone Methylation (Histone 3 Lysine 36 Methylation), Hypoxia (HIF1 Signaling), Apoptosis (Intrinsic Apoptosis) and MYC Signaling are potential drivers of the disease. Mustard has active ingredients which can increase disease drivers like Oncogenic Cancer Epigenetics (CpG Methylation), Oncogenic Histone Methylation (Histone 3 Lysine 36 Methylation), Hypoxia (HIF1 Signaling), Apoptosis (Intrinsic Apoptosis) and MYC Signaling and hence intake should be reduced.

Similarly, eating Mustard can have scientific benefits for healthy individuals who have a gene mutation in FLT3 which suggests potential risk of cancer. This is because of biochemical pathways PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), RAS-RAF Signaling (RAS Signaling), MAPK Signaling and JAK-STAT Signaling. But reduce intake of Mustard when at genetic risk of cancer due to mutation of gene ATM due to its manipulation of biochemical pathways DNA Repair (ATM Signaling), DNA Repair (Homology Directed Repair), Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (ERBB2 Signaling) causing cancer drivers to increase.

The takeaway being – for Myeloproliferative Neoplasms, Monoclonal gammopathy of undetermined significance and other cancers individual conditions can influence if foods like Mustard are recommended or not. As conditions like ongoing treatments, supplements, habits and other conditions change; the nutrition plan must be re-designed and personalized. Whether Myeloproliferative Neoplasms or Monoclonal gammopathy of undetermined significance or other cancer types -, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are also key decision factors for creating a personalized nutrition plan.



Why is the choice of foods important for cancer?

Foods like Mustard typically contain more than one active ingredient at varying concentrations. Each of these active ingredients like Myricetin has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for Myeloproliferative Neoplasms, Monoclonal gammopathy of undetermined significance and other cancers there is a need to personalize which foods and supplements to take and regularly evaluate if foods like Mustard are recommended or not.

Mustard for Monoclonal gammopathy of undetermined significance taking Lenalidomide treatment and mustard for  Myeloproliferative Neoplasms along with Decitabine treatment

So some of the example questions one may have related to Mustard can be: Is Mustard beneficial for me? Should I eat it when at genetic cancer risk due to mutation of gene ATM? Should I eat Mustard when a mutation of a gene FLT3 is identified? Should I eat Mustard when diagnosed with Myeloproliferative Neoplasms? Should I eat Mustard when diagnosed with Monoclonal gammopathy of undetermined significance? Should I eat Mustard when on Decitabine treatment? Should I continue eating Mustard if my treatment changes from Decitabine to Lenalidomide? Are the implications of taking Mustard in Monoclonal gammopathy of undetermined significance the same as Myeloproliferative Neoplasms? And so on.

Mustard and cancer

Mustard contains numerous functional compounds that have various health benefits.It improves the anti-inflammatory activities of mustard leaf and mustard leaf fermented with this microorganism may serve as a proper diet for the treatment of inflammation.

Mustard contains many active ingredients like Myricetin, Beta-sitosterol, Astragalin, Citric Acid, Linoleic Acid and many other Bioactives at different concentrations. The molecular pathways which are regulated by Mustard include Oncogenic Cancer Epigenetics (CpG Methylation), Oncogenic Histone Methylation (Histone 3 Lysine 36 Methylation), P53 Signaling, PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), DNA Repair (ATM Signaling) and many others. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Mustard and supplements is an important decision to be made. And not necessarily the same food choices are scientifically best for all individuals.

Include Mustard in my nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is dependent on multiple factors. Just like the same treatment does not work for every cancer patient, based on individual context the Mustard may have scientific benefits or have adverse interactions. Along with which cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Any benefits of Mustard for Myeloproliferative Neoplasms with Decitabine treatment?

Myeloproliferative Neoplasms is known to have mutations in gene like JAK2, CALR and TET2 and others which together cause biochemical pathway changes in Oncogenic Cancer Epigenetics (CpG Methylation), Oncogenic Histone Methylation (Histone 3 Lysine 36 Methylation), Hypoxia (HIF1 Signaling), Apoptosis (Intrinsic Apoptosis) and MYC Signaling. A cancer treatment like Decitabine has molecular action on a unique set of biochemical pathways . The treatment intent is to have a good overlap with the cancer driving pathways and reduce the disease drivers. In such conditions foods which can scientifically cancel out the treatment effect by reducing the overlap between the cancer driving pathways and treatment are candidates for reducing intake of or completely avoid. For example – in the case of Myeloproliferative Neoplasms and treatment Decitabine – Mustard is not recommended. Mustard impacts pathways or processes like Oncogenic Cancer Epigenetics (CpG Methylation) and Oncogenic Histone Methylation (Histone 3 Lysine 36 Methylation) which can negate the effects of the treatment.

2. Any benefits of Mustard for Monoclonal gammopathy of undetermined significance with Lenalidomide treatment?

Monoclonal gammopathy of undetermined significance is defined and driven by specific genetic mutations like LATS2, ZMYM2 and CDK8 leading to biochemical pathway changes in P53 Signaling, PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), NFKB Signaling, Hypoxia (HIF1 Signaling) and WNT Betacatenin Signaling. Also treatments like Lenalidomide have molecular action on a unique set of biochemical pathways. Mustard should be considered for Monoclonal gammopathy of undetermined significance while on Lenalidomide treatment. Mustard impacts pathways or processes like P53 Signaling and PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling) which can either reduce drivers of Monoclonal gammopathy of undetermined significance and/or improve Lenalidomide treatment effect.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Any benefits of Mustard for gene ATM associated cancer genetic risk?

Many companies offer gene panel tests for evaluating genetic risk to different cancers. These panels cover genes like ATM and many others associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. The intent of the genetic testing of ATM is for diagnosis and/or to find out any potential risk factors for cancer. ATM mutation causes biochemical pathways or processes like DNA Repair (ATM Signaling), DNA Repair (Homology Directed Repair), Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (ERBB2 Signaling) to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like DNA Repair (ATM Signaling), DNA Repair (Homology Directed Repair), Stem Cell Signaling, Estrogen Signaling and Growth Factor Signaling (ERBB2 Signaling). Intake of foods like Mustard should be reduced when there is a mutation of ATM for risk of Chronic myelomonocytic leukemia and Mantle Cell Lymphoma. Mustard impacts pathways or processes like DNA Repair (ATM Signaling) and creates adverse effects with ATM mutation.

4. Any benefits of Mustard for gene FLT3 associated cancer genetic risk?

FLT3 is also one of many genes available in panels for cancer risk testing. FLT3 mutation causes biochemical pathways or processes like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), RAS-RAF Signaling (RAS Signaling), MAPK Signaling and JAK-STAT Signaling to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling), RAS-RAF Signaling (RAS Signaling), MAPK Signaling and JAK-STAT Signaling. Intake of foods like Mustard should be considered when Acute Myeloid Leukemia risk is identified due to gene FLT3 mutation. Mustard impacts biochemical pathways or processes like PI3K-AKT-MTOR Signaling (PI3K-AKT Signaling) associated with genetic risk to FLT3 mutation.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Personalized nutrition planning for cancer can inform if foods like Mustard are recommended or not. Nutrition is the single most effective tool which cancer patients can control and nutrition decisions are dependent on questions like “Is Mustard beneficial for me?”

The addon personalized nutrition planning for cancer is a software approach based on molecular science. The addon approach supports cancers like Myeloproliferative Neoplasms, Monoclonal gammopathy of undetermined significance and others along with commonly reported genomic group clusters.

To get your personalized nutrition plan – enter details like cancer indication (example Myeloproliferative Neoplasms, name of current cancer and non-cancer treatments; habits and lifestyle conditions.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

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Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


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