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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

For which cancer is Rowal beneficial for?

Mar 19, 2022

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Highlights

Nutrition is the single most effective tool which cancer patients can control for managing cancers like ATRX+ Diffuse Glioma or Basal Cell Carcinoma – hence it is important to identify those Foods and Supplements which are scientifically recommended for you. A frequently asked question is if foods like Rowal are beneficial for cancer and along with which treatments? There is a mis-conception that all plant-based foods are good for all cancers and all of them are equal in terms of their benefits or their lack of. The reality is that some plant-based foods will be better than others for a specific type of cancer, treatments and other conditions. So Rowal benefits will vary and the answer is contextual.

For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made.

So are there types of cancer where Rowal has more benefits? Yes! Rowal is beneficial for Basal Cell Carcinoma patients taking Vismodegib treatment. But has adverse interactions for ATRX+ Diffuse Glioma patients on Procarbazine treatment.

For Basal Cell Carcinoma along with Vismodegib – biochemical pathways like Vitamin D Signaling, Cell Cycle (Mitotic Cell Cycle), Nutrient sensing (AMPK Signaling), Cell Cycle (Proliferation) and Oncogenic Cancer Epigenetics (HDAC Class 1 Signaling) are potential drivers of the disease. Rowal has active ingredients which can manipulate these biochemical pathways to reduce the disease drivers and hence are scientifically beneficial. But for ATRX+ Diffuse Glioma along with Procarbazine – biochemical pathways like Oxidative Stress, DNA Repair (Homology Directed Repair), DNA Repair (Base Excision Repair), Notch Signaling (NOTCH1 Signaling) and Direct Repair are potential drivers of the disease. Rowal has active ingredients which can increase disease drivers like Oxidative Stress, DNA Repair (Homology Directed Repair), DNA Repair (Base Excision Repair), Notch Signaling (NOTCH1 Signaling) and Direct Repair and hence intake should be reduced.

Similarly, eating Rowal can have scientific benefits for healthy individuals who have a gene mutation in MLH1 which suggests potential risk of cancer. This is because of biochemical pathways Estrogen Signaling, MYC Signaling, Stem Cell Signaling, P53 Signaling and Growth Factor Signaling (EGFR Signaling). But reduce intake of Rowal when at genetic risk of cancer due to mutation of gene ASXL1 due to its manipulation of biochemical pathways Oncogenic Cancer Epigenetics (CpG Methylation) and Suppressive Histone Methylation (Histone 3 Lysine 27 Methylation) causing cancer drivers to increase.

The takeaway being – for ATRX+ Diffuse Glioma, Basal Cell Carcinoma and other cancers individual conditions can influence if foods like Rowal are recommended or not. As conditions like ongoing treatments, supplements, habits and other conditions change; the nutrition plan must be re-designed and personalized. Whether ATRX+ Diffuse Glioma or Basal Cell Carcinoma or other cancer types -, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are also key decision factors for creating a personalized nutrition plan.



Why is the choice of foods important for cancer?

Foods like Rowal typically contain more than one active ingredient at varying concentrations. Each of these active ingredients like Liquiritigenin has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for ATRX+ Diffuse Glioma, Basal Cell Carcinoma and other cancers there is a need to personalize which foods and supplements to take and regularly evaluate if foods like Rowal are recommended or not.

Rowal for Basal Cell Carcinoma taking Vismodegib treatment and rowal for  ATRX+ Diffuse Glioma along with Procarbazine treatment

So some of the example questions one may have related to Rowal can be: Is Rowal beneficial for me? Should I eat it when at genetic cancer risk due to mutation of gene ASXL1? Should I eat Rowal when a mutation of a gene MLH1 is identified? Should I eat Rowal when diagnosed with ATRX+ Diffuse Glioma? Should I eat Rowal when diagnosed with Basal Cell Carcinoma? Should I eat Rowal when on Procarbazine treatment? Should I continue eating Rowal if my treatment changes from Procarbazine to Vismodegib? Are the implications of taking Rowal in Basal Cell Carcinoma the same as ATRX+ Diffuse Glioma? And so on.

Rowal and cancer

Pangium edule also known as Rowal fruit is a tall tree in the Flacourtiaceae family and is native to Malesia, Melanesia and Micronesia. Apart from Rowal fruit it is also known as pangi, pakem, sis, rimmel, kepayang football fruit and Sis Nut.

Rowal contains many active ingredients like Liquiritigenin, Vitamin A, Vitamin C and many other Bioactives at different concentrations. The molecular pathways which are regulated by Rowal include Oxidative Stress, Vitamin D Signaling, Cell Cycle (Mitotic Cell Cycle), Oncogenic Cancer Epigenetics (CpG Methylation), Suppressive Histone Methylation (Histone 3 Lysine 27 Methylation) and many others. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Rowal and supplements is an important decision to be made. And not necessarily the same food choices are scientifically best for all individuals.

Include Rowal in my nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is dependent on multiple factors. Just like the same treatment does not work for every cancer patient, based on individual context the Rowal may have scientific benefits or have adverse interactions. Along with which cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Any benefits of Rowal for ATRX+ Diffuse Glioma with Procarbazine treatment?

ATRX+ Diffuse Glioma is known to have mutations in gene like ATRX, IDH1 and MGMT and others which together cause biochemical pathway changes in Oxidative Stress, DNA Repair (Homology Directed Repair), DNA Repair (Base Excision Repair), Notch Signaling (NOTCH1 Signaling) and Direct Repair. A cancer treatment like Procarbazine has molecular action on a unique set of biochemical pathways . The treatment intent is to have a good overlap with the cancer driving pathways and reduce the disease drivers. In such conditions foods which can scientifically cancel out the treatment effect by reducing the overlap between the cancer driving pathways and treatment are candidates for reducing intake of or completely avoid. For example – in the case of ATRX+ Diffuse Glioma and treatment Procarbazine – Rowal is not recommended. Rowal impacts pathways or processes like Oxidative Stress which can negate the effects of the treatment.

2. Any benefits of Rowal for Basal Cell Carcinoma with Vismodegib treatment?

Basal Cell Carcinoma is defined and driven by specific genetic mutations like PTCH1, CSMD3 and CSMD1 leading to biochemical pathway changes in Vitamin D Signaling, Cell Cycle (Mitotic Cell Cycle), Nutrient sensing (AMPK Signaling), Cell Cycle (Proliferation) and Oncogenic Cancer Epigenetics (HDAC Class 1 Signaling). Also treatments like Vismodegib have molecular action on a unique set of biochemical pathways. Rowal should be considered for Basal Cell Carcinoma while on Vismodegib treatment. Rowal impacts pathways or processes like Vitamin D Signaling and Cell Cycle (Mitotic Cell Cycle) which can either reduce drivers of Basal Cell Carcinoma and/or improve Vismodegib treatment effect.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Any benefits of Rowal for gene ASXL1 associated cancer genetic risk?

Many companies offer gene panel tests for evaluating genetic risk to different cancers. These panels cover genes like ASXL1 and many others associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. The intent of the genetic testing of ASXL1 is for diagnosis and/or to find out any potential risk factors for cancer. ASXL1 mutation causes biochemical pathways or processes like Oncogenic Cancer Epigenetics (CpG Methylation) and Suppressive Histone Methylation (Histone 3 Lysine 27 Methylation) to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like Oncogenic Cancer Epigenetics (CpG Methylation) and Suppressive Histone Methylation (Histone 3 Lysine 27 Methylation). Intake of foods like Rowal should be reduced when there is a mutation of ASXL1 for risk of Chronic myelomonocytic leukemia and Myelodysplastic Syndrome. Rowal impacts pathways or processes like Oncogenic Cancer Epigenetics (CpG Methylation) and Suppressive Histone Methylation (Histone 3 Lysine 27 Methylation) and creates adverse effects with ASXL1 mutation.

4. Any benefits of Rowal for gene MLH1 associated cancer genetic risk?

MLH1 is also one of many genes available in panels for cancer risk testing. MLH1 mutation causes biochemical pathways or processes like Estrogen Signaling, MYC Signaling, Stem Cell Signaling, P53 Signaling and Growth Factor Signaling (EGFR Signaling) to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like Estrogen Signaling, MYC Signaling, Stem Cell Signaling, P53 Signaling and Growth Factor Signaling (EGFR Signaling). Intake of foods like Rowal should be considered when Colon cancer risk is identified due to gene MLH1 mutation. Rowal impacts biochemical pathways or processes like Estrogen Signaling and MYC Signaling associated with genetic risk to MLH1 mutation.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Personalized nutrition planning for cancer can inform if foods like Rowal are recommended or not. Nutrition is the single most effective tool which cancer patients can control and nutrition decisions are dependent on questions like “Is Rowal beneficial for me?”

The addon personalized nutrition planning for cancer is a software approach based on molecular science. The addon approach supports cancers like ATRX+ Diffuse Glioma, Basal Cell Carcinoma and others along with commonly reported genomic group clusters.

To get your personalized nutrition plan – enter details like cancer indication (example ATRX+ Diffuse Glioma, name of current cancer and non-cancer treatments; habits and lifestyle conditions.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

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Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


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