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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

For which cancer is Turmeric beneficial for?

Mar 17, 2022

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Highlights

Nutrition is the single most effective tool which cancer patients can control for managing cancers like Testicular Germ Cell Tumors or Lung Cancer in the Never Smokers – hence it is important to identify those Foods and Supplements which are scientifically recommended for you. A frequently asked question is if foods like Turmeric are beneficial for cancer and along with which treatments? There is a mis-conception that all plant-based foods are good for all cancers and all of them are equal in terms of their benefits or their lack of. The reality is that some plant-based foods will be better than others for a specific type of cancer, treatments and other conditions. So Turmeric benefits will vary and the answer is contextual.

For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made.

So are there types of cancer where Turmeric has more benefits? Yes! Turmeric is beneficial for Lung Cancer in the Never Smokers patients taking Erlotinib treatment. But has adverse interactions for Testicular Germ Cell Tumors patients on Ifosfamide treatment.

For Lung Cancer in the Never Smokers along with Erlotinib – biochemical pathways like Apoptosis (Intrinsic Apoptosis), P53 Signaling, MAPK Signaling (ERK Signaling), RAS-RAF Signaling (RAF Signaling) and Notch Signaling (NOTCH1 Signaling) are potential drivers of the disease. Turmeric has active ingredients which can manipulate these biochemical pathways to reduce the disease drivers and hence are scientifically beneficial. But for Testicular Germ Cell Tumors along with Ifosfamide – biochemical pathways like Oxidative Stress, DNA Repair (Homology Directed Repair), DNA Repair (Base Excision Repair), Cell Cycle (Proliferation) and DNA Repair (Global Genome Nucleotide Excision Repair) are potential drivers of the disease. Turmeric has active ingredients which can increase disease drivers like Oxidative Stress, DNA Repair (Homology Directed Repair), DNA Repair (Base Excision Repair), Cell Cycle (Proliferation) and DNA Repair (Global Genome Nucleotide Excision Repair) and hence intake should be reduced.

Similarly, eating Turmeric can have scientific benefits for healthy individuals who have a gene mutation in SMAD4 which suggests potential risk of cancer. This is because of biochemical pathways Lipid Metabolism (Arachidonic Acid Metabolism), MYC Signaling, Stem Cell Signaling, MAPK Signaling and Growth Factor Signaling (EGFR Signaling). But reduce intake of Turmeric when at genetic risk of cancer due to mutation of gene CREBBP due to its manipulation of biochemical pathways Histone/Protein Acetylation causing cancer drivers to increase.

The takeaway being – for Testicular Germ Cell Tumors, Lung Cancer in the Never Smokers and other cancers individual conditions can influence if foods like Turmeric are recommended or not. As conditions like ongoing treatments, supplements, habits and other conditions change; the nutrition plan must be re-designed and personalized. Whether Testicular Germ Cell Tumors or Lung Cancer in the Never Smokers or other cancer types -, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are also key decision factors for creating a personalized nutrition plan.



Why is the choice of foods important for cancer?

Foods like Turmeric typically contain more than one active ingredient at varying concentrations. Each of these active ingredients like D-limonene has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for Testicular Germ Cell Tumors, Lung Cancer in the Never Smokers and other cancers there is a need to personalize which foods and supplements to take and regularly evaluate if foods like Turmeric are recommended or not.

Turmeric for Lung Cancer in the Never Smokers taking Erlotinib treatment and turmeric for Testicular Germ Cell Tumors along with Ifosfamide treatment

So some of the example questions one may have related to Turmeric can be: Is Turmeric beneficial for me? Should I eat it when at genetic cancer risk due to mutation of gene CREBBP? Should I eat Turmeric when a mutation of a gene SMAD4 is identified? Should I eat Turmeric when diagnosed with Testicular Germ Cell Tumors? Should I eat Turmeric when diagnosed with Lung Cancer in the Never Smokers? Should I eat Turmeric when on Ifosfamide treatment? Should I continue eating Turmeric if my treatment changes from Ifosfamide to Erlotinib? Are the implications of taking Turmeric in Lung Cancer in the Never Smokers the same as Testicular Germ Cell Tumors? And so on.

Turmeric and cancer

Turmeric (Curcuma longa), a commonly used spice throughout the world, has been shown to exhibit antiinflammatory, antimicrobial, antioxidant, and antineoplastic properties.

Turmeric contains many active ingredients like D-limonene, Curcumin, Beta-sitosterol, Bisdemethoxycurcumin, Eucalyptol and many other Bioactives at different concentrations. The molecular pathways which are regulated by Turmeric include Oxidative Stress, Apoptosis (Intrinsic Apoptosis), P53 Signaling, Histone/Protein Acetylation, Lipid Metabolism (Arachidonic Acid Metabolism) and many others. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Turmeric and supplements is an important decision to be made. And not necessarily the same food choices are scientifically best for all individuals.

Include Turmeric in my nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is dependent on multiple factors. Just like the same treatment does not work for every cancer patient, based on individual context the Turmeric may have scientific benefits or have adverse interactions. Along with which cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Any benefits of Turmeric for Testicular Germ Cell Tumors with Ifosfamide treatment?

Testicular Germ Cell Tumors is known to have mutations in gene like KIT, KRAS and PTMA and others which together cause biochemical pathway changes in Oxidative Stress, DNA Repair (Homology Directed Repair), DNA Repair (Base Excision Repair), Cell Cycle (Proliferation) and DNA Repair (Global Genome Nucleotide Excision Repair). A cancer treatment like Ifosfamide has molecular action on a unique set of biochemical pathways . The treatment intent is to have a good overlap with the cancer driving pathways and reduce the disease drivers. In such conditions foods which can scientifically cancel out the treatment effect by reducing the overlap between the cancer driving pathways and treatment are candidates for reducing intake of or completely avoid. For example – in the case of Testicular Germ Cell Tumors and treatment Ifosfamide – Turmeric is not recommended. Turmeric impacts pathways or processes like Oxidative Stress which can negate the effects of the treatment.

2. Any benefits of Turmeric for Lung Cancer in the Never Smokers with Erlotinib treatment?

Lung Cancer in the Never Smokers is defined and driven by specific genetic mutations like TP53, EGFR and TTN leading to biochemical pathway changes in Apoptosis (Intrinsic Apoptosis), P53 Signaling, MAPK Signaling (ERK Signaling), RAS-RAF Signaling (RAF Signaling) and Notch Signaling (NOTCH1 Signaling). Also treatments like Erlotinib have molecular action on a unique set of biochemical pathways. Turmeric should be considered for Lung Cancer in the Never Smokers while on Erlotinib treatment. Turmeric impacts pathways or processes like Apoptosis (Intrinsic Apoptosis) and P53 Signaling which can either reduce drivers of Lung Cancer in the Never Smokers and/or improve Erlotinib treatment effect.

For Which Cancer Is Turmeric Beneficial For?

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Any benefits of Turmeric for gene CREBBP associated cancer genetic risk?

Many companies offer gene panel tests for evaluating genetic risk to different cancers. These panels cover genes like CREBBP and many others associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. The intent of the genetic testing of CREBBP is for diagnosis and/or to find out any potential risk factors for cancer. CREBBP mutation causes biochemical pathways or processes like Histone/Protein Acetylation to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like Histone/Protein Acetylation. Intake of foods like Turmeric should be reduced when there is a mutation of CREBBP for risk of Follicular Lymphoma and Non-Hodgkin Lymphoma. Turmeric impacts pathways or processes like Histone/Protein Acetylation and creates adverse effects with CREBBP mutation.

4. Any benefits of Turmeric for gene SMAD4 associated cancer genetic risk?

SMAD4 is also one of many genes available in panels for cancer risk testing. SMAD4 mutation causes biochemical pathways or processes like Lipid Metabolism (Arachidonic Acid Metabolism), MYC Signaling, Stem Cell Signaling, MAPK Signaling and Growth Factor Signaling (EGFR Signaling) to get impacted. Cancer molecular endpoints like apoptosis, proliferation and spread are impacted by pathways like Lipid Metabolism (Arachidonic Acid Metabolism), MYC Signaling, Stem Cell Signaling, MAPK Signaling and Growth Factor Signaling (EGFR Signaling). Intake of foods like Turmeric should be considered when Colon cancer and Gallbladder Cancer risk is identified due to gene SMAD4 mutation. Turmeric impacts biochemical pathways or processes like Lipid Metabolism (Arachidonic Acid Metabolism) and MYC Signaling associated with genetic risk to SMAD4 mutation.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Personalized nutrition planning for cancer can inform if foods like Turmeric are recommended or not. Nutrition is the single most effective tool which cancer patients can control and nutrition decisions are dependent on questions like “Is Turmeric beneficial for me?”

The addon personalized nutrition planning for cancer is a software approach based on molecular science. The addon approach supports cancers like Testicular Germ Cell Tumors, Lung Cancer in the Never Smokers and others along with commonly reported genomic group clusters.

To get your personalized nutrition plan – enter details like cancer indication (example Testicular Germ Cell Tumors, name of current cancer and non-cancer treatments; habits and lifestyle conditions.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

sample-report

Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


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