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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

Apple intake should be reduced for these cancer types!

Dec 27, 2021

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Highlights

Apple like other plant based foods have health benefits and is included in the diet of cancer patients and those with genetic risk of cancer. But, the intake of Apple may need to be reduced for some cancers and cancer treatments. A belief but a myth is that everything plant based can only benefit and do no harm. That is true if the food intake is in moderation. For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made. Hence the frequently asked question related to cancer is “What Food Should I Eat and What Should I Avoid?”.

Benefits of foods like Apple can be scientifically explained for cancer patients with EGFR+ Lip and Oral Cavity Cancer taking Afatinib treatment. But reduce intake of Apple for Hemangioblastoma and Bevacizumab treatment . 

Similarly, the benefits of eating Apple can be scientifically explained for healthy individuals who are at genetic risk of cancer due to mutation of the gene BRCA2. But reduce intake of Apple when at genetic risk of cancer due to mutation of gene ALK. 

The takeaway being – for cancer individual conditions can influence if food like Apple is recommended or not. As conditions like ongoing treatments and supplements change the nutrition plan must be personalized again. Which cancer, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are decision factors for your nutrition. 



Why is the choice of foods important for cancer?

Foods typically contain more than one active ingredient at varying concentrations. Each of these active ingredients has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for cancer there is a need to personalize which foods and supplements to take and check if foods like Apple are recommended. 

Apple for Cancer Treatment and Genetic Risk

So some of the example questions you may have related to Apple can be: Should you eat it when at genetic cancer risk due to mutation of gene ALK? Should you eat Apple when a mutation of a gene BRCA2 is identified? Should you eat Apple when diagnosed with Hemangioblastoma? Should you eat Apple when diagnosed with EGFR+ Lip and Oral Cavity Cancer? Should you eat Apple when on Bevacizumab treatment? Should you continue eating Apple if your treatment changes from Bevacizumab to Afatinib? Are the implications of taking Apple in EGFR+ Lip and Oral Cavity Cancer the same as Hemangioblastoma? And so on.

Apple and cancer

Apples are one of the most popular fruits. Apples are a good source of fiber and vitamin C.These substances help neutralize free radicals. Free radicals are reactive molecules that can build up as a result of natural processes and environmental pressures.

They also contain polyphenols, which may have numerous health benefits.

Apple contains many active ingredients like Epicatechin and Caffeic Acid at different concentrations. The molecular pathways which are regulated by Apple include Extracellular Matrix Remodelling, P53 Signaling, JAK-STAT Signaling, TGFB Signaling and Angiogenesis. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Apple and supplements is an important decision to be made. And not necessarily the same food choices are scientifically correct across individuals.

Include Apple in Your Cancer Nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is It Depends!. Just like the same treatment does not work for every cancer patient, based on individual context the Apple may have scientific benefits or have adverse interactions. Along with cancer  – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question. 

1. Continue Eating Apple for Hemangioblastoma and Bevacizumab treatment?

Hemangioblastoma is defined and driven by specific genetic mutations like VHL and FANCA leading to biochemical pathway changes in TGFB Signaling, Hypoxia, Angiogenesis and DNA Repair. A cancer treatment like Bevacizumab has molecular action on a unique set of biochemical pathways. The treatment intent is to have a good overlap between the cancer driving pathways and those manipulated by the treatment. In such conditions foods which have an opposing effect to the treatment and reduce the overlap between the cancer driving pathways and treatment should be avoided. As an example, Apple intake should be reduced by cancer patients with Hemangioblastoma while on Bevacizumab treatment. Apple impacts pathways or processes like TGFB Signaling which can negate the effects of the treatment. The factors to be considered when choosing foods and supplements are which cancer, treatments and supplements being taken currently, which age group, gender, height, weight, lifestyle habits and any genetic information.

2. Continue Eating Apple for EGFR+ Lip and Oral Cavity Cancer and Afatinib treatment?

EGFR+ Lip and Oral Cavity Cancer is defined and driven by specific genetic mutations like EGFR and TP53 leading to biochemical pathway changes in P53 Signaling, Extracellular Matrix Remodelling, Epithelial to Mesenchymal Transition, PI3K-AKT-MTOR Signaling and Growth Factor Signaling. A cancer treatment like Afatinib has molecular action on a unique set of biochemical pathways. Apple should be considered by cancer patients with EGFR+ Lip and Oral Cavity Cancer while on Afatinib treatment. Apple impacts pathways or processes like P53 Signaling and Extracellular Matrix Remodelling which can either obstruct drivers of EGFR+ Lip and Oral Cavity Cancer and/or improve Afatinib treatment effect.

For which cancers should Apple be avoided

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Continue Eating Apple for ALK Associated Cancer Genetic Risk? 

Many companies offer gene panels testing for evaluating genetic risk to different cancers. These panels cover genes associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. Testing of these genes may confirm a diagnosis or identify risk to some cancers. ALK is one of the genes available in panels for cancer risk testing. 

ALK mutation causes biochemical pathways or processes like Angiogenesis, JAK-STAT Signaling, Stem Cell Signaling and Growth Factor Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Apple should be reduced when mutation of ALK for risk of Central Nervous System is identified. Apple impacts pathways or processes like Angiogenesis and JAK-STAT Signaling and creates adverse effects with ALK mutation and related conditions.

4. Continue Eating Apple for BRCA2 Associated Cancer Genetic Risk? 

BRCA2 is also one of many genes available in panels for cancer risk testing. BRCA2 mutation causes biochemical pathways or processes like P53 Signaling, Angiogenesis, Androgen Signaling, Stem Cell Signaling and PI3K-AKT-MTOR Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Apple should be considered when mutation of BRCA2 for risk of Breast Cancer and Ovarian Cancer is identified. Apple impacts pathways or processes like P53 Signaling and Angiogenesis and creates a supportive effect in those with BRCA2 mutation and related conditions.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion 

Nutrition for cancer (including supplements and foods like Apple) and treatments may not be the same for everyone. 

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

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Personalized Nutrition for Cancer!

Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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