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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Cucumber intake should be reduced for these cancer types!

Nov 25, 2021

Estimated reading time: 7 minutes
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Highlights

Cucumber like other plant based foods have health benefits and is included in the diet of cancer patients and those with genetic risk of cancer. But, the intake of Cucumber may need to be reduced for some cancers and cancer treatments. A belief but a myth is that everything plant based can only benefit and do no harm. That is true if the food intake is in moderation. For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made. Hence the frequently asked question related to cancer is “What Food Should I Eat and What Should I Avoid?”.

Benefits of foods like Cucumber can be scientifically explained for cancer patients with Anal Squamous cell carcinoma taking Fluorouracil treatment. But reduce intake of Cucumber for Anaplastic Large Cell Lymphoma and Prednisone treatment .

Similarly, the benefits of eating Cucumber can be scientifically explained for healthy individuals who are at genetic risk of cancer due to mutation of the gene LZTR1. But reduce intake of Cucumber when at genetic risk of cancer due to mutation of gene ERCC2.

The takeaway being – for cancer individual conditions can influence if food like Cucumber is recommended or not. As conditions like ongoing treatments and supplements change the nutrition plan must be personalized again. Which cancer, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are decision factors for your nutrition.



Why is the choice of foods important for cancer?

Foods typically contain more than one active ingredient at varying concentrations. Each of these active ingredients has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for cancer there is a need to personalize which foods and supplements to take and check if foods like Cucumber are recommended.

Cucumber for Cancer Treatment and Genetic Risk

So some of the example questions you may have related to Cucumber can be: Should you eat it when at genetic cancer risk due to mutation of gene ERCC2? Should you eat Cucumber when a mutation of a gene LZTR1 is identified? Should you eat Cucumber when diagnosed with Anaplastic Large Cell Lymphoma? Should you eat Cucumber when diagnosed with Anal Squamous cell carcinoma? Should you eat Cucumber when on Prednisone treatment? Should you continue eating Cucumber if your treatment changes from Prednisone to Fluorouracil? Are the implications of taking Cucumber in Anal Squamous cell carcinoma the same as Anaplastic Large Cell Lymphoma? And so on.

Cucumber and cancer

Cucumber (Cucumis sativus), is creeping vine plant in the Cucurbitaceae gourd family with cylindrical fruits, native to South Asia. Cucumbers provide various nutrients but are low in calories, fat, cholesterol, and sodium.  Following are some of the potential health benefits of cucumber:

Cucumber contains many active ingredients like Cucurbitacin I and Beta-sitosterol at different concentrations. The molecular pathways which are regulated by Cucumber include MAPK Signaling, Cancer Epigenetics, Oncogenic Cancer Epigenetics, P53 Signaling, NFKB Signaling, Adherens junction, Angiogenesis and MYC Signaling. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Cucumber and supplements is an important decision to be made. And not necessarily the same food choices are scientifically correct across individuals.

Include Cucumber in Your Cancer Nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is It Depends!. Just like the same treatment does not work for every cancer patient, based on individual context the Cucumber may have scientific benefits or have adverse interactions. Along with cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Continue Eating Cucumber for Anaplastic Large Cell Lymphoma and Prednisone treatment?

Anaplastic Large Cell Lymphoma is defined and driven by specific genetic mutations like NPM1-ALK and NOTCH1 leading to biochemical pathway changes in MYC Signaling, NFKB Signaling, MAPK Signaling, Growth Factor Signaling and PI3K-AKT-MTOR Signaling. A cancer treatment like Prednisone has molecular action on a unique set of biochemical pathways. The treatment intent is to have a good overlap between the cancer driving pathways and those manipulated by the treatment. In such conditions foods which have an opposing effect to the treatment and reduce the overlap between the cancer driving pathways and treatment should be avoided. As an example, Cucumber intake should be reduced by cancer patients with Anaplastic Large Cell Lymphoma while on Prednisone treatment. Cucumber impacts pathways or processes like MYC Signaling and NFKB Signaling which can negate the effects of the treatment. The factors to be considered when choosing foods and supplements are which cancer, treatments and supplements being taken currently, which age group, gender, height, weight, lifestyle habits and any genetic information.

2. Continue Eating Cucumber for Anal Squamous cell carcinoma and Fluorouracil treatment?

Anal Squamous cell carcinoma is defined and driven by specific genetic mutations like PIK3CA and FIP1L1 leading to biochemical pathway changes in Adherens junction, P53 Signaling, Oxidative Stress, PI3K-AKT-MTOR Signaling and Angiogenesis. A cancer treatment like Fluorouracil has molecular action on a unique set of biochemical pathways. Cucumber should be considered by cancer patients with Anal Squamous cell carcinoma while on Fluorouracil treatment. Cucumber impacts pathways or processes like Adherens junction and P53 Signaling which can either obstruct drivers of Anal Squamous cell carcinoma and/or improve Fluorouracil treatment effect.

For which cancers should Cucumber be avoided

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Continue Eating Cucumber for ERCC2 Associated Cancer Genetic Risk?

Many companies offer gene panels testing for evaluating genetic risk to different cancers. These panels cover genes associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. Testing of these genes may confirm a diagnosis or identify risk to some cancers. ERCC2 is one of the genes available in panels for cancer risk testing.

ERCC2 mutation causes biochemical pathways or processes like MAPK Signaling, Cancer Epigenetics, Stem Cell Signaling, DNA Repair and Angiogenesis to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Cucumber should be reduced when mutation of ERCC2 for risk of Skin Cancer is identified. Cucumber impacts pathways or processes like MAPK Signaling and Cancer Epigenetics and creates adverse effects with ERCC2 mutation and related conditions.

4. Continue Eating Cucumber for LZTR1 Associated Cancer Genetic Risk?

LZTR1 is also one of many genes available in panels for cancer risk testing. LZTR1 mutation causes biochemical pathways or processes like Angiogenesis, Oncogenic Cancer Epigenetics, MAPK Signaling, Stem Cell Signaling and RAS-RAF Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Cucumber should be considered when mutation of LZTR1 for risk of Central Nervous System and Hematological Cancer is identified. Cucumber impacts pathways or processes like Angiogenesis and Oncogenic Cancer Epigenetics and creates a supportive effect in those with LZTR1 mutation and related conditions.

For Which Cancer Types Should you Avoid Cucumber

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Nutrition for cancer (including supplements and foods like Cucumber) and treatments may not be the same for everyone.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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