addonfinal2

What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

0
(0)

Which Foods and Supplements to Avoid for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Nov 17, 2021

Estimated reading time: 10 minutes
Home » Blogs » Which Foods and Supplements to Avoid for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Highlights

No two cancers are the same and neither should your nutrition be. When diagnosed with cancer or at risk of cancer – one immediate question is “What Should I Eat Differently Starting Now?” and “Which Supplements Should I Take and Avoid”. The answer is “It Depends”. It depends on which genetic mutations your tests identified. It depends on which cancer, which ongoing treatments and supplements. It depends on your age, weight, height, lifestyle, allergies and habits. The answer to “What Should I Eat Differently” and “Which Supplements Should I Take and Avoid” for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC) also requires understanding of how the food and supplements included in your diet manipulate the molecular pathways which are relevant for cancer and interactions with your treatment.

Internet search to find answers will never be personalized to your cancer type such as PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC) and lifestyle conditions. Cancers are driven by biochemical pathways and therefore the answers to nutrition questions have to be based on molecular science irrespective of whether one understands it or not.  

For example foods like Bamboo and Beetroot are recommended when undergoing Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC). But Rosemary and Quinoa are recommended when treatment changes to Fluorouracil. 

Similarly Diosmin supplements are recommended with Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC). But Caffeine supplements are recommended when treatment changes to Fluorouracil. So always personalize your nutrition to your cancer gene mutations and other factors.



What is PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the different subtypes of Head and Neck Squamous Cell Carcinoma (HNSCC). In this subtype of HNSCC, a gene called PIK3CA is mutated or overexpressed. The defects or aberrations or mutations in this gene can either drive cancer (tumor promoters) or remove brakes on cancer progression (tumor suppressors). PIK3CA gene mutations are prevalent in cancer Head and Neck Squamous Cell Carcinoma (HNSCC). You can visit NIH for information on the prevalence of genetic mutations across cancers. (Reference: Steven N Hart et al, Hum Mutat,. 2020

Diet for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)

Why Are Some Foods Recommended in the Diet for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Foods and Supplements contain different active ingredients which manipulate different molecular pathways relevant to cancers such as PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC). Genetic mutations and cancer conditions cause specific molecular pathways to become disrupted. Hence, those foods and supplements are recommended which do not disrupt those molecular pathways further and instead reverse the disruption. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), cancer pathways or processes like NFKB Signaling, MYC Signaling, Cell Cycle, Hypoxia, Glucocorticoid Signaling, Vitamin D Signaling, Angiogenesis, Adherens junction, DNA Repair, WNT Beta Catenin Signaling, Focal Adhesion, Replication Stress, PI3K-AKT-MTOR Signaling, Notch Signaling, Microtubule Dynamics, MAPK Signaling, P53 Signaling, Oncogenic Cancer Epigenetics, Netrin Signaling, Nucleotide metabolism, RUNX Signaling, Amino Acid Metabolism, Epithelial to Mesenchymal Transition and Oxidative Stress get disrupted. Choose those foods and supplements which contain active ingredients which cancel the molecular pathways disruption. Those supplements which interact with the treatments and disrupt the cancer molecular pathways further should be avoided.

The nutrition/diet for cancer such as PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC) depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. 

Example Foods to Eat with Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)

Foods and Supplements to take and avoid for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)

Recommended Foods

Bamboo: Bamboo contains active ingredients like Beta-sitosterol, Citric Acid and Linoleic Acid. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Beta-sitosterol manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Bamboo are recommended as part of the diet along with treatment Cisplatin for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Beetroot: Beetroot contains active ingredients like Linoleic Acid, Citric Acid and Folic Acid. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Linoleic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Beetroot are recommended as part of the diet along with treatment Cisplatin for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Reduce Intake of These Foods

Parsnip:  Parsnip contains active ingredients like Folic Acid, Ferulic Acid and Linoleic Acid. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Folic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Parsnip when undergoing Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Spinach:  Spinach contains active ingredients like Citric Acid, Linoleic Acid and Folic Acid. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, MAPK Signaling is also disrupted and drives the cancer. Citric Acid manipulates the molecular pathways like MAPK Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Spinach when undergoing Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Which Supplements To Avoid with Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Unlike foods, supplements are high concentrations of active ingredients and hence important to understand the interactions with Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Feverfew: Feverfew contains active ingredients Centaureidin and Parthenolide. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Oxidative Stress and Cell Cycle are also disrupted and drive the cancer. Centaureidin manipulates the molecular pathways like Oxidative Stress and Cell Cycle so as to disrupt them further. Hence avoid Feverfew supplements when undergoing Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Black Seed: Black Seed contains active ingredients Carvacrol, Thymol and Thymoquinone. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Cell Cycle Checkpoints and Apoptosis are also disrupted and drive the cancer. Carvacrol manipulates the molecular pathways like Cell Cycle Checkpoints and Apoptosis so as to disrupt them further. Hence avoid Black Seed supplements when undergoing Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Should I take this Nutritional Supplement with Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Diosmin:  Diosmin contains active ingredients Diosmetin and Diosmin. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Cell Cycle Checkpoints and Apoptosis are also disrupted and drive the cancer. Diosmetin manipulates the molecular pathways like Cell Cycle Checkpoints and Apoptosis so as to cancel these disruptions. Hence Diosmin supplements are recommended with Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Curcumin:  For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Cell Cycle Checkpoints and Apoptosis are also disrupted and drive the cancer. Curcumin manipulates the molecular pathways like Cell Cycle Checkpoints and Apoptosis so as to cancel these disruptions.  Hence Curcumin supplements are recommended with Cisplatin treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

For PIK3CA+ Head and Neck Squamous Cell Carcinoma avoid these foods and supplements!

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Example Foods to Eat with Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)

Recommended Foods

Rosemary: Rosemary contains active ingredients like Betulinic Acid, Eucalyptol and Naringenin. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Betulinic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Rosemary are recommended along with treatment Fluorouracil for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Quinoa: Quinoa contains active ingredients like Protocatechuic Acid, Linoleic Acid and Folic Acid. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Protocatechuic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Quinoa are recommended along with treatment Fluorouracil for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Reduce Intake of These Foods

Kumquat:  Kumquat contains active ingredients like Naringetol, Naringenin and Linoleic Acid. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Microtubule Dynamics is also disrupted and drives the cancer. Naringetol manipulates the molecular pathways like Microtubule Dynamics so as to disrupt them further. Hence avoid or reduce the intake of foods like Kumquat when undergoing Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Honey:  Honey contains active ingredients like Pinostrobin. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, MAPK Signaling is also disrupted and drives the cancer. Pinostrobin manipulates the molecular pathways like MAPK Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Honey when undergoing Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Which Supplements To Avoid with Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Unlike foods, supplements are high concentrations of active ingredients and hence important to understand the interactions with Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Nutmeg:  Nutmeg contains active ingredients Beta-caryophyllene, Beta-sitosterol and Butyric Acid. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Oxidative Stress and Angiogenesis are also disrupted and drive the cancer. Beta-caryophyllene manipulates the molecular pathways like Oxidative Stress and Angiogenesis so as to disrupt them further. Hence avoid Nutmeg supplements when undergoing Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Horseradish:  Horseradish contains active ingredients Benzyl Isothiocyanate, Folic Acid and Isorhamnetin. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Adherens junction and Oxidative Stress are also disrupted and drive the cancer. Benzyl Isothiocyanate manipulates the molecular pathways like Adherens junction and Oxidative Stress so as to disrupt them further. Hence avoid Horseradish supplements when undergoing Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Should I take this Nutritional Supplement with Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Caffeine:  For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, P53 Signaling and Adherens junction are also disrupted and drive the cancer. Caffeine manipulates the molecular pathways like P53 Signaling and Adherens junction so as to cancel these disruptions. Hence Caffeine supplements are recommended with Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Birch:  Birch contains active ingredients Betulinic Acid and Lupeol. For PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Adherens junction and Oxidative Stress are also disrupted and drive the cancer. Betulinic Acid manipulates the molecular pathways like Adherens junction and Oxidative Stress so as to cancel these disruptions.  Hence Birch supplements are recommended with Fluorouracil treatment for PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

In Conclusion

Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as PIK3CA+ Head and Neck Squamous Cell Carcinoma (HNSCC).

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


You can also read this in

How useful was this post?

Click on a star to rate it!

Average rating 0 / 5. Vote count: 0

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?