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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Grape intake should be reduced for these cancer types! 

Nov 9, 2021

Estimated reading time: 7 minutes
Home » Blogs » Grape intake should be reduced for these cancer types! 

Highlights

Grape like other plant based foods have health benefits and is included in the diet of cancer patients and those with genetic risk of cancer. But, the intake of Grape may need to be reduced for some cancers and cancer treatments. A belief but a myth is that everything plant based can only benefit and do no harm. That is true if the food intake is in moderation. For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made. Hence the frequently asked question related to cancer is “What Food Should I Eat and What Should I Avoid?”.

Benefits of foods like Grape can be scientifically explained for cancer patients with Erdheim Chester Disease taking Vemurafenib treatment. But reduce intake of Grape for Colorectal Adenocarcinoma and Fluorouracil treatment .

Similarly, the benefits of eating Grape can be scientifically explained for healthy individuals who are at genetic risk of cancer due to mutation of the gene BLM. But reduce intake of Grape when at genetic risk of cancer due to mutation of gene SMARCA4.

The takeaway being – for cancer individual conditions can influence if food like Grape is recommended or not. As conditions like ongoing treatments and supplements change the nutrition plan must be personalized again. Which cancer, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are decision factors for your nutrition.



Why is the choice of foods important for cancer?

Foods typically contain more than one active ingredient at varying concentrations. Each of these active ingredients has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for cancer there is a need to personalize which foods and supplements to take and check if foods like Grape are recommended.

Grape for Cancer Treatment and Genetic Risk

So some of the example questions you may have related to Grape can be: Should you eat it when at genetic cancer risk due to mutation of gene SMARCA4? Should you eat Grape when a mutation of a gene BLM is identified? Should you eat Grape when diagnosed with Colorectal Adenocarcinoma? Should you eat Grape when diagnosed with Erdheim Chester Disease? Should you eat Grape when on Fluorouracil treatment? Should you continue eating Grape if your treatment changes from Fluorouracil to Vemurafenib? Are the implications of taking Grape in Erdheim Chester Disease the same as Colorectal Adenocarcinoma? And so on.

Grape and cancer

Grapes are the fruits of grapevines and vary in colours and forms. They can be crimson, black, dark blue, yellow, green, orange, or pink. Two of the most common grapevines are Vitis vinifera and Vitis labrusca. They are rich in antioxidants and have many health benefits. Following are some of the potential health benefits of grapes:

Grape contains many active ingredients like Oleic Acid and Berberine at different concentrations. The molecular pathways which are regulated by Grape include Cancer Epigenetics, PI3K-AKT-MTOR Signaling, Epithelial to Mesenchymal Transition, Estrogen Signaling, Focal Adhesion, Adherens junction, Angiogenesis and Androgen Signaling. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Grape and supplements is an important decision to be made. And not necessarily the same food choices are scientifically correct across individuals.

Include Grape in Your Cancer Nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is It Depends!. Just like the same treatment does not work for every cancer patient, based on individual context the Grape may have scientific benefits or have adverse interactions. Along with cancer – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question.

1. Continue Eating Grape for Colorectal Adenocarcinoma and Fluorouracil treatment?

Colorectal Adenocarcinoma is defined and driven by specific genetic mutations like APC and TP53 leading to biochemical pathway changes in Epithelial to Mesenchymal Transition, Focal Adhesion, Oncogenic Cancer Epigenetics, PI3K-AKT-MTOR Signaling and Small Molecule Transport. A cancer treatment like Fluorouracil has molecular action on a unique set of biochemical pathways. The treatment intent is to have a good overlap between the cancer driving pathways and those manipulated by the treatment. In such conditions foods which have an opposing effect to the treatment and reduce the overlap between the cancer driving pathways and treatment should be avoided. As an example, Grape intake should be reduced by cancer patients with Colorectal Adenocarcinoma while on Fluorouracil treatment. Grape impacts pathways or processes like Epithelial to Mesenchymal Transition and Focal Adhesion which can negate the effects of the treatment. The factors to be considered when choosing foods and supplements are which cancer, treatments and supplements being taken currently, which age group, gender, height, weight, lifestyle habits and any genetic information.

2. Continue Eating Grape for Erdheim Chester Disease and Vemurafenib treatment?

Erdheim Chester Disease is defined and driven by specific genetic mutations like BRAF and MAP2K1 leading to biochemical pathway changes in Adherens junction, PI3K-AKT-MTOR Signaling, MAPK Signaling and RAS-RAF Signaling. A cancer treatment like Vemurafenib has molecular action on a unique set of biochemical pathways. Grape should be considered by cancer patients with Erdheim Chester Disease while on Vemurafenib treatment. Grape impacts pathways or processes like Adherens junction and PI3K-AKT-MTOR Signaling which can either obstruct drivers of Erdheim Chester Disease and/or improve Vemurafenib treatment effect.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Continue Eating Grape for SMARCA4 Associated Cancer Genetic Risk?

Many companies offer gene panels testing for evaluating genetic risk to different cancers. These panels cover genes associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. Testing of these genes may confirm a diagnosis or identify risk to some cancers. SMARCA4 is one of the genes available in panels for cancer risk testing.

SMARCA4 mutation causes biochemical pathways or processes like Androgen Signaling, Cancer Epigenetics, Replication Stress, Stem Cell Signaling and Cell Cycle to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Grape should be reduced when mutation of SMARCA4 for risk of Sarcoma is identified. Grape impacts pathways or processes like Androgen Signaling and Cancer Epigenetics and creates adverse effects with SMARCA4 mutation and related conditions.

4. Continue Eating Grape for BLM Associated Cancer Genetic Risk?

BLM is also one of many genes available in panels for cancer risk testing. BLM mutation causes biochemical pathways or processes like Angiogenesis, Estrogen Signaling, Stem Cell Signaling, Post Translation Modification and Growth Factor Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Grape should be considered when mutation of BLM for risk of Breast Cancer is identified. Grape impacts pathways or processes like Angiogenesis and Estrogen Signaling and creates a supportive effect in those with BLM mutation and related conditions.

For Which Cancer Types Should you Avoid Grape

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion

Nutrition for cancer (including supplements and foods like Grape) and treatments may not be the same for everyone.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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