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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which Foods and Supplements to Avoid for IDH+ Cholangiocarcinoma?

Oct 29, 2021

Estimated reading time: 6 minutes
Home » Blogs » Which Foods and Supplements to Avoid for IDH+ Cholangiocarcinoma?

Highlights

No two cancers are the same and neither should your nutrition be. When diagnosed with cancer or at risk of cancer – one immediate question is “What Should I Eat Differently Starting Now?” and “Which Supplements Should I Take and Avoid”. The answer is “It Depends”. It depends on which genetic mutations your tests identified. It depends on which cancer, which ongoing treatments and supplements. It depends on your age, weight, height, lifestyle, allergies and habits. The answer to “What Should I Eat Differently” and “Which Supplements Should I Take and Avoid” for IDH+ Cholangiocarcinoma also requires understanding of how the food and supplements included in your diet manipulate the molecular pathways which are relevant for cancer and interactions with your treatment.

Internet search to find answers will never be personalized to your cancer type such as IDH+ Cholangiocarcinoma and lifestyle conditions. Cancers are driven by biochemical pathways and therefore the answers to nutrition questions have to be based on molecular science irrespective of whether one understands it or not.  

For example foods like Eggplant and Sweet Potato are recommended when undergoing Ivosidenib treatment for IDH+ Cholangiocarcinoma. Similarly Neem Extract supplements are recommended with Ivosidenib treatment for IDH+ Cholangiocarcinoma. So always personalize your nutrition to your cancer gene mutations and other factors.



What is IDH+ Cholangiocarcinoma?

IDH+ Cholangiocarcinoma is one of the different subtypes of Cholangiocarcinoma. In this subtype of Cholangiocarcinoma, mutation of a gene called IDH1 is detected. The defects or aberrations or mutations in this gene can either drive cancer (tumor promoters) or remove brakes on cancer progression (tumor suppressors).  IDH1 gene mutations are prevalent in Cholangiocarcinoma. You can visit NIH for information on the prevalence of genetic mutations across cancers. (Reference: Steven N Hart et al, Hum Mutat,. 2020)

Diet for IDH+ Cholangiocarcinoma

Why Are Some Foods Recommended in the Diet for IDH+ Cholangiocarcinoma?

Foods and Supplements contain different active ingredients which manipulate different molecular pathways relevant to cancers such as IDH+ Cholangiocarcinoma. Genetic mutations and cancer conditions cause specific molecular pathways to become disrupted. Hence, those foods and supplements are recommended which do not disrupt those molecular pathways further and instead reverse the disruption. For IDH+ Cholangiocarcinoma, cancer pathways or processes like Inflammation, NFKB Signaling, Oncogenic Cancer Epigenetics, MYC Signaling, WNT Beta Catenin Signaling, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, Hypoxia, JAK-STAT Signaling and MAPK Signaling get disrupted. Choose those foods and supplements which contain active ingredients which cancel the molecular pathways disruption. Those supplements which interact with the treatments and disrupt the cancer molecular pathways further should be avoided.

The nutrition/diet for cancer such as IDH+ Cholangiocarcinoma depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. 

Example Foods to Eat with Ivosidenib treatment for IDH+ Cholangiocarcinoma

Foods and Supplements to take and avoid for IDH+ Cholangiocarcinoma

Recommended Foods

Eggplant: Eggplant contains active ingredients like Delphinidin, Citric Acid and Linoleic Acid. For IDH+ Cholangiocarcinoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Delphinidin manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Eggplant are recommended along with treatment Ivosidenib for IDH+ Cholangiocarcinoma.

Sweet Potato: Sweet Potato contains active ingredients like Linoleic Acid, Citric Acid and Oleic Acid. For IDH+ Cholangiocarcinoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Linoleic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Sweet Potato are recommended along with treatment Ivosidenib for IDH+ Cholangiocarcinoma.

Reduce Intake of These Foods

Swiss Chard:  Swiss Chard contains active ingredients like Folic Acid, Ferulic Acid and P-coumaric Acid. For IDH+ Cholangiocarcinoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Folic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Swiss Chard when undergoing Ivosidenib treatment for IDH+ Cholangiocarcinoma.

Spinach:  Spinach contains active ingredients like Kaempferol, Citric Acid and Linoleic Acid. For IDH+ Cholangiocarcinoma, along with other pathways, Oncogenic Cancer Epigenetics is also disrupted and drives the cancer. Kaempferol manipulates the molecular pathways like Oncogenic Cancer Epigenetics so as to disrupt them further. Hence avoid or reduce the intake of foods like Spinach when undergoing Ivosidenib treatment for IDH+ Cholangiocarcinoma.

Science of Right Personalized Nutrition for Cancer

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Which Supplements To Avoid with Ivosidenib treatment for IDH+ Cholangiocarcinoma?

Unlike foods, supplements are high concentrations of active ingredients and hence important to understand the interactions with Ivosidenib treatment for IDH+ Cholangiocarcinoma.

Silymarin: Silymarin contains active ingredients Silibinin. For IDH+ Cholangiocarcinoma, along with other pathways, WNT Beta Catenin Signaling and MAPK Signaling are also disrupted and drive the cancer. Silibinin manipulates the molecular pathways like WNT Beta Catenin Signaling and MAPK Signaling so as to disrupt them further. Hence avoid Silymarin supplements when undergoing Ivosidenib treatment for IDH+ Cholangiocarcinoma.

Caffeine: For IDH+ Cholangiocarcinoma, along with other pathways, Oncogenic Cancer Epigenetics and MAPK Signaling are also disrupted and drive the cancer. Caffeine manipulates the molecular pathways like Oncogenic Cancer Epigenetics and MAPK Signaling so as to disrupt them further. Hence avoid Caffeine supplements when undergoing Ivosidenib treatment for IDH+ Cholangiocarcinoma.

Should I take this Nutritional Supplement with Ivosidenib treatment for IDH+ Cholangiocarcinoma?

Neem Extract:  Neem Extract contains active ingredients Azadirachtin, Gedunin and Nimbolide. For IDH+ Cholangiocarcinoma, along with other pathways, WNT Beta Catenin Signaling and MAPK Signaling are also disrupted and drive the cancer. Azadirachtin manipulates the molecular pathways like WNT Beta Catenin Signaling and MAPK Signaling so as to cancel these disruptions. Hence Neem Extract supplements are recommended with Ivosidenib treatment for IDH+ Cholangiocarcinoma.

Vitamin B2:  For IDH+ Cholangiocarcinoma, along with other pathways, Oncogenic Cancer Epigenetics are also disrupted and drive the cancer. Vitamin B2 manipulates the molecular pathways like Oncogenic Cancer Epigenetics so as to cancel these disruptions.  Hence Vitamin B2 supplements are recommended with Ivosidenib treatment for IDH+ Cholangiocarcinoma.

In Conclusion

Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as IDH+ Cholangiocarcinoma.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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