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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Bell pepper intake should be reduced for these cancer types!

Oct 26, 2021

Estimated reading time: 7 minutes
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Highlights

Bell pepper like other plant based foods have health benefits and is included in the diet of cancer patients and those with genetic risk of cancer. But, the intake of Bell pepper may need to be reduced for some cancers and cancer treatments. A belief but a myth is that everything plant based can only benefit and do no harm. That is true if the food intake is in moderation. For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made. Hence the frequently asked question related to cancer is “What Food Should I Eat and What Should I Avoid?”.

Benefits of foods like Bell pepper can be scientifically explained for cancer patients with Relapsed Refractory Diffuse Large B-Cell Lymphoma taking Vincristine treatment. But reduce intake of Bell pepper for Dermatofibrosarcoma protuberans and Imatinib treatment . 

Similarly, the benefits of eating Bell pepper can be scientifically explained for healthy individuals who are at genetic risk of cancer due to mutation of the gene XPC. But reduce intake of Bell pepper when at genetic risk of cancer due to mutation of gene WT1. 

The takeaway being – for cancer individual conditions can influence if food like Bell pepper is recommended or not. As conditions like ongoing treatments and supplements change the nutrition plan must be personalized again. Which cancer, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are decision factors for your nutrition. 



Why is the choice of foods important for cancer?

Foods typically contain more than one active ingredient at varying concentrations. Each of these active ingredients has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for cancer there is a need to personalize which foods and supplements to take and check if foods like Bell pepper are recommended. 

Bell pepper for Cancer Treatment and Genetic Risk

So some of the example questions you may have related to Bell pepper can be: Should you eat it when at genetic cancer risk due to mutation of gene WT1? Should you eat Bell pepper when a mutation of a gene XPC is identified? Should you eat Bell pepper when diagnosed with Dermatofibrosarcoma protuberans? Should you eat Bell pepper when diagnosed with Relapsed Refractory Diffuse Large B-Cell Lymphoma? Should you eat Bell pepper when on Imatinib treatment? Should you continue eating Bell pepper if your treatment changes from Imatinib to Vincristine? Are the implications of taking Bell pepper in Relapsed Refractory Diffuse Large B-Cell Lymphoma the same as Dermatofibrosarcoma protuberans? And so on.

Bell pepper and cancer

Bell pepper, also known as sweet pepper, pepper or capsicum, is a bell shaped fruit, available in different colours including red, yellow, orange and green. Bell peppers are rich in antioxidants and have many health benefits. Following are some of the potential health benefits of bell peppers:

Bell pepper contains many active ingredients like Folic Acid and Capsaicin at different concentrations. The molecular pathways which are regulated by Bell pepper include MAPK Signaling, Endoplasmic Reticulum Stress, Apoptosis, Oxidative Stress, Angiogenesis and MYC Signaling. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Bell pepper and supplements is an important decision to be made. And not necessarily the same food choices are scientifically correct across individuals.

Include Bell pepper in Your Cancer Nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is It Depends!. Just like the same treatment does not work for every cancer patient, based on individual context the Bell pepper may have scientific benefits or have adverse interactions. Along with cancer  – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question. 

1. Continue Eating Bell pepper for Dermatofibrosarcoma protuberans and Imatinib treatment?

Dermatofibrosarcoma protuberans is defined and driven by specific genetic mutations like PIK3C2B and CDKN2A leading to biochemical pathway changes in MYC Signaling, MAPK Signaling, Growth Factor Signaling, Cell Cycle and PI3K-AKT-MTOR Signaling. A cancer treatment like Imatinib has molecular action on a unique set of biochemical pathways. The treatment intent is to have a good overlap between the cancer driving pathways and those manipulated by the treatment. In such conditions foods which have an opposing effect to the treatment and reduce the overlap between the cancer driving pathways and treatment should be avoided. As an example, Bell pepper intake should be reduced by cancer patients with Dermatofibrosarcoma protuberans while on Imatinib treatment. Bell pepper impacts pathways or processes like MYC Signaling and MAPK Signaling which can negate the effects of the treatment. The factors to be considered when choosing foods and supplements are which cancer, treatments and supplements being taken currently, which age group, gender, height, weight, lifestyle habits and any genetic information.

2. Continue Eating Bell pepper for Relapsed Refractory Diffuse Large B-Cell Lymphoma and Vincristine treatment?

Relapsed Refractory Diffuse Large B-Cell Lymphoma is defined and driven by specific genetic mutations like CREBBP and KMT2D leading to biochemical pathway changes in Apoptosis, Oxidative Stress, Cell Cycle, PI3K-AKT-MTOR Signaling and MYC Signaling. A cancer treatment like Vincristine has molecular action on a unique set of biochemical pathways. Bell pepper should be considered by cancer patients with Relapsed Refractory Diffuse Large B-Cell Lymphoma while on Vincristine treatment. Bell pepper impacts pathways or processes like Apoptosis and Oxidative Stress which can either obstruct drivers of Relapsed Refractory Diffuse Large B-Cell Lymphoma and/or improve Vincristine treatment effect.

For which cancers should Bell Pepper be avoided

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Continue Eating Bell pepper for WT1 Associated Cancer Genetic Risk? 

Many companies offer gene panels testing for evaluating genetic risk to different cancers. These panels cover genes associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. Testing of these genes may confirm a diagnosis or identify risk to some cancers. WT1 is one of the genes available in panels for cancer risk testing. 

WT1 mutation causes biochemical pathways or processes like Endoplasmic Reticulum Stress, MYC Signaling, Stem Cell Signaling, Cell Cycle and Oncogenic Cancer Epigenetics to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Bell pepper should be reduced when mutation of WT1 for risk of Kidney Cancer is identified. Bell pepper impacts pathways or processes like Endoplasmic Reticulum Stress and MYC Signaling and creates adverse effects with WT1 mutation and related conditions.

4. Continue Eating Bell pepper for XPC Associated Cancer Genetic Risk? 

XPC is also one of many genes available in panels for cancer risk testing. XPC mutation causes biochemical pathways or processes like Angiogenesis, MAPK Signaling, Stem Cell Signaling and DNA Repair to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Bell pepper should be considered when mutation of XPC for risk of Skin Cancer is identified. Bell pepper impacts pathways or processes like Angiogenesis and MAPK Signaling and creates a supportive effect in those with XPC mutation and related conditions.

For Which Cancer Types Should you Avoid Bell pepper

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion 

Nutrition for cancer (including supplements and foods like Bell pepper) and treatments may not be the same for everyone. 

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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