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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Barley intake should be reduced for these cancer types!

Oct 24, 2021

Estimated reading time: 7 minutes
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Highlights

Barley like other plant based foods have health benefits and is included in the diet of cancer patients and those with genetic risk of cancer. But, the intake of Barley may need to be reduced for some cancers and cancer treatments. A belief but a myth is that everything plant based can only benefit and do no harm. That is true if the food intake is in moderation. For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made. Hence the frequently asked question related to cancer is “What Food Should I Eat and What Should I Avoid?”.

Benefits of foods like Barley can be scientifically explained for cancer patients with Monoclonal gammopathy of undetermined significance taking Dexamethasone treatment. But reduce intake of Barley for BRAF+ Metastatic Melanoma and Binimetinib treatment . 

Similarly, the benefits of eating Barley can be scientifically explained for healthy individuals who are at genetic risk of cancer due to mutation of the gene CDC73. But reduce intake of Barley when at genetic risk of cancer due to mutation of gene ALK. 

The takeaway being – for cancer individual conditions can influence if food like Barley is recommended or not. As conditions like ongoing treatments and supplements change the nutrition plan must be personalized again. Which cancer, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are decision factors for your nutrition. 



Why is the choice of foods important for cancer?

Foods typically contain more than one active ingredient at varying concentrations. Each of these active ingredients has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for cancer there is a need to personalize which foods and supplements to take and check if foods like Barley are recommended. 

 Barley for Cancer Treatment and Genetic Risk

So some of the example questions you may have related to Barley can be: Should you eat it when at genetic cancer risk due to mutation of gene ALK? Should you eat Barley when a mutation of a gene CDC73 is identified? Should you eat Barley when diagnosed with BRAF+ Metastatic Melanoma? Should you eat Barley when diagnosed with Monoclonal gammopathy of undetermined significance? Should you eat Barley when on Binimetinib treatment? Should you continue eating Barley if your treatment changes from Binimetinib to Dexamethasone? Are the implications of taking Barley in Monoclonal gammopathy of undetermined significance the same as BRAF+ Metastatic Melanoma? And so on.

Barley and cancer

Barley is a cereal grain consumed across the globe. The whole grain barley is rich in dietary fiber and is highly nutritious. The phytochemicals present in whole grain barley have strong antioxidant and antiproliferative properties. (Emmanuel Idehen et al, J Food Drug Anal., 2017)

Following are some of the potential health benefits of barley (Susan M Tosh and Nicolas Bordenave, Nutr Rev., 2020):

  • May help reduce bad cholesterol and improve heart health
  • May help decrease blood glucose
  • May help modulate gut microbiota.

Barley contains many active ingredients like Folic Acid, Linoleic Acid and Beta-sitosterol at different concentrations. The molecular pathways which are regulated by Barley include MAPK Signaling, Cell Cycle Checkpoints, Cell Cycle, Epithelial to Mesenchymal Transition, JAK-STAT Signaling, Angiogenesis and MYC Signaling. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Barley and supplements is an important decision to be made. And not necessarily the same food choices are scientifically correct across individuals.

Include Barley in Your Cancer Nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is It Depends!. Just like the same treatment does not work for every cancer patient, based on individual context the Barley may have scientific benefits or have adverse interactions. Along with cancer  – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question. 

1. Continue Eating Barley for BRAF+ Metastatic Melanoma and Binimetinib treatment?

BRAF+ Metastatic Melanoma is defined and driven by specific genetic mutations like BRAF and TTN leading to biochemical pathway changes in MYC Signaling, MAPK Signaling, Growth Factor Signaling, Small Molecule Transport and Extracellular Matrix Remodelling. A cancer treatment like Binimetinib has molecular action on a unique set of biochemical pathways. The treatment intent is to have a good overlap between the cancer driving pathways and those manipulated by the treatment. In such conditions foods which have an opposing effect to the treatment and reduce the overlap between the cancer driving pathways and treatment should be avoided. As an example, Barley intake should be reduced by cancer patients with BRAF+ Metastatic Melanoma while on Binimetinib treatment. Barley impacts pathways or processes like MYC Signaling and MAPK Signaling which can negate the effects of the treatment. The factors to be considered when choosing foods and supplements are which cancer, treatments and supplements being taken currently, which age group, gender, height, weight, lifestyle habits and any genetic information.

2. Continue Eating Barley for Monoclonal gammopathy of undetermined significance and Dexamethasone treatment?

Monoclonal gammopathy of undetermined significance is defined and driven by specific genetic mutations like LATS2 and ZMYM2 leading to biochemical pathway changes in Cell Cycle, Epithelial to Mesenchymal Transition, MYC Signaling, PI3K-AKT-MTOR Signaling and Hypoxia. A cancer treatment like Dexamethasone has molecular action on a unique set of biochemical pathways. Barley should be considered by cancer patients with Monoclonal gammopathy of undetermined significance while on Dexamethasone treatment. Barley impacts pathways or processes like Cell Cycle and Epithelial to Mesenchymal Transition which can either obstruct drivers of Monoclonal gammopathy of undetermined significance and/or improve Dexamethasone treatment effect.

For which cancers should Barley be avoided

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Continue Eating Barley for ALK Associated Cancer Genetic Risk? 

Many companies offer gene panels testing for evaluating genetic risk to different cancers. These panels cover genes associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. Testing of these genes may confirm a diagnosis or identify risk to some cancers. ALK is one of the genes available in panels for cancer risk testing. 

ALK mutation causes biochemical pathways or processes like Angiogenesis, JAK-STAT Signaling, Stem Cell Signaling and Growth Factor Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Barley should be reduced when mutation of ALK for risk of Central Nervous System is identified. Barley impacts pathways or processes like Angiogenesis and JAK-STAT Signaling and creates adverse effects with ALK mutation and related conditions.

4. Continue Eating Barley for CDC73 Associated Cancer Genetic Risk? 

CDC73 is also one of many genes available in panels for cancer risk testing. CDC73 mutation causes biochemical pathways or processes like Cell Cycle Checkpoints, MYC Signaling, Stem Cell Signaling, WNT Betacatenin Signaling and Angiogenesis to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Barley should be considered when mutation of CDC73 for risk of Neuroendocrine Cancer is identified. Barley impacts pathways or processes like Cell Cycle Checkpoints and MYC Signaling and creates a supportive effect in those with CDC73 mutation and related conditions.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion 

Nutrition for cancer (including supplements and foods like Barley) and treatments may not be the same for everyone. 

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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