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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Anise intake should be reduced for these cancer types!

Oct 21, 2021

Estimated reading time: 7 minutes
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Highlights

Anise like other plant based foods have health benefits and is included in the diet of cancer patients and those with genetic risk of cancer. But, the intake of Anise may need to be reduced for some cancers and cancer treatments. A belief but a myth is that everything plant based can only benefit and do no harm. That is true if the food intake is in moderation. For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made. Hence the frequently asked question related to cancer is “What Food Should I Eat and What Should I Avoid?”.

Benefits of foods like Anise can be scientifically explained for cancer patients with Waldenstrom macroglobulinemia taking Ibrutinib treatment. But reduce intake of Anise for Malignant fibrous histiocytoma and Everolimus treatment . 

Similarly, the benefits of eating Anise can be scientifically explained for healthy individuals who are at genetic risk of cancer due to mutation of the gene DICER1. But reduce intake of Anise when at genetic risk of cancer due to mutation of gene ALK. 

The takeaway being – for cancer individual conditions can influence if food like Anise is recommended or not. As conditions like ongoing treatments and supplements change the nutrition plan must be personalized again. Which cancer, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are decision factors for your nutrition. 



Why is the choice of foods important for cancer?

Foods typically contain more than one active ingredient at varying concentrations. Each of these active ingredients has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for cancer there is a need to personalize which foods and supplements to take and check if foods like Anise are recommended. 

Anise for Cancer Treatment and Genetic Risk

So some of the example questions you may have related to Anise can be: Should you eat it when at genetic cancer risk due to mutation of gene ALK? Should you eat Anise when a mutation of a gene DICER1 is identified? Should you eat Anise when diagnosed with Malignant fibrous histiocytoma? Should you eat Anise when diagnosed with Waldenstrom macroglobulinemia? Should you eat Anise when on Everolimus treatment? Should you continue eating Anise if your treatment changes from Everolimus to Ibrutinib? Are the implications of taking Anise in Waldenstrom macroglobulinemia the same as Malignant fibrous histiocytoma? And so on.

Anise and cancer

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Anise (Pimpinella anisum), also known as aniseed, is an annual herb native to the eastern Mediterranean region and Southwest Asia. It tastes like licorice and is generally used as a flavoring agent. Following are some of the potential health benefits of Anise:

Anise contains many active ingredients like Folic Acid, Anethole and Apigenin at different concentrations. The molecular pathways which are regulated by Anise include Stem Cell Signaling, Chemokine Signaling, P53 Signaling, JAK-STAT Signaling, NFKB Signaling, Microtubule Dynamics, WNT Betacatenin Signaling and MYC Signaling. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Anise and supplements is an important decision to be made. And not necessarily the same food choices are scientifically correct across individuals.

Include Anise in Your Cancer Nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is It Depends!. Just like the same treatment does not work for every cancer patient, based on individual context the Anise may have scientific benefits or have adverse interactions. Along with cancer  – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question. 

1. Continue Eating Anise for Malignant fibrous histiocytoma and Everolimus treatment?

Malignant fibrous histiocytoma is defined and driven by specific genetic mutations like TP53 and CHD1 leading to biochemical pathway changes in WNT Betacatenin Signaling, Microtubule Dynamics, Epithelial to Mesenchymal Transition, MAPK Signaling and PI3K-AKT-MTOR Signaling. A cancer treatment like Everolimus has molecular action on a unique set of biochemical pathways. The treatment intent is to have a good overlap between the cancer driving pathways and those manipulated by the treatment. In such conditions foods which have an opposing effect to the treatment and reduce the overlap between the cancer driving pathways and treatment should be avoided. As an example, Anise intake should be reduced by cancer patients with Malignant fibrous histiocytoma while on Everolimus treatment. Anise impacts pathways or processes like WNT Betacatenin Signaling and Microtubule Dynamics which can negate the effects of the treatment. The factors to be considered when choosing foods and supplements are which cancer, treatments and supplements being taken currently, which age group, gender, height, weight, lifestyle habits and any genetic information.

2. Continue Eating Anise for Waldenstrom macroglobulinemia and Ibrutinib treatment?

Waldenstrom macroglobulinemia is defined and driven by specific genetic mutations like MYD88 and CXCR4 leading to biochemical pathway changes in MYC Signaling, NFKB Signaling, Chemokine Signaling and Cancer Epigenetics. A cancer treatment like Ibrutinib has molecular action on a unique set of biochemical pathways. Anise should be considered by cancer patients with Waldenstrom macroglobulinemia while on Ibrutinib treatment. Anise impacts pathways or processes like MYC Signaling and NFKB Signaling which can either obstruct drivers of Waldenstrom macroglobulinemia and/or improve Ibrutinib treatment effect.

For which cancers should Anise be avoided

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Continue Eating Anise for ALK Associated Cancer Genetic Risk? 

Many companies offer gene panels testing for evaluating genetic risk to different cancers. These panels cover genes associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. Testing of these genes may confirm a diagnosis or identify risk to some cancers. ALK is one of the genes available in panels for cancer risk testing. 

ALK mutation causes biochemical pathways or processes like JAK-STAT Signaling, Stem Cell Signaling, Growth Factor Signaling and Angiogenesis to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Anise should be reduced when mutation of ALK for risk of Central Nervous System is identified. Anise impacts pathways or processes like JAK-STAT Signaling and Stem Cell Signaling and creates adverse effects with ALK mutation and related conditions.

4. Continue Eating Anise for DICER1 Associated Cancer Genetic Risk? 

DICER1 is also one of many genes available in panels for cancer risk testing. DICER1 mutation causes biochemical pathways or processes like P53 Signaling, Chemokine Signaling, Stem Cell Signaling, Estrogen Signaling and EPHRIN Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Anise should be considered when mutation of DICER1 for risk of Ovarian Cancer and Neuroendocrine Cancer is identified. Anise impacts pathways or processes like P53 Signaling and Chemokine Signaling and creates a supportive effect in those with DICER1 mutation and related conditions.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion 

Nutrition for cancer (including supplements and foods like Anise) and treatments may not be the same for everyone. 

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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