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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Alfalfa intake should be reduced for these cancer types!

Oct 18, 2021

Estimated reading time: 7 minutes
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Highlights

Alfalfa like other plant based foods have health benefits and is included in the diet of cancer patients and those with genetic risk of cancer. But, the intake of Alfalfa may need to be reduced for some cancers and cancer treatments. A belief but a myth is that everything plant based can only benefit and do no harm. That is true if the food intake is in moderation. For example, grapefruit with certain medications is not recommended. Also spinach with some blood thinning medications can cause adverse interactions and hence intake should be reduced. For cancer, nutrition which includes food and supplements are important decisions which need to be made. Hence the frequently asked question related to cancer is “What Food Should I Eat and What Should I Avoid?”.

Benefits of foods like Alfalfa can be scientifically explained for cancer patients with EGFR+ Cervical Squamous Cell Carcinoma taking Bevacizumab treatment. But reduce intake of Alfalfa for Non-Hodgkin Lymphoma and Ifosfamide treatment . 

Similarly, the benefits of eating Alfalfa can be scientifically explained for healthy individuals who are at genetic risk of cancer due to mutation of the gene AXIN2. But reduce intake of Alfalfa when at genetic risk of cancer due to mutation of gene RAD50. 

The takeaway being – for cancer individual conditions can influence if food like Alfalfa is recommended or not. As conditions like ongoing treatments and supplements change the nutrition plan must be personalized again. Which cancer, current treatments and supplements, age, gender, weight, height, lifestyle and genetic conditions are decision factors for your nutrition. 



Why is the choice of foods important for cancer?

Foods typically contain more than one active ingredient at varying concentrations. Each of these active ingredients has a unique molecular biological mechanism of action. Cancer like most diseases is driven by specific biochemical pathways and molecular interventions of the pathway can be beneficial or create adverse interactions. Hence for cancer there is a need to personalize which foods and supplements to take and check if foods like Alfalfa are recommended. 

So some of the example questions you may have related to Alfalfa can be: Should you eat it when at genetic cancer risk due to mutation of gene RAD50? Should you eat Alfalfa when a mutation of a gene AXIN2 is identified? Should you eat Alfalfa when diagnosed with Non-Hodgkin Lymphoma? Should you eat Alfalfa when diagnosed with EGFR+ Cervical Squamous Cell Carcinoma? Should you eat Alfalfa when on Ifosfamide treatment? Should you continue eating Alfalfa if your treatment changes from Ifosfamide to Bevacizumab? Are the implications of taking Alfalfa in EGFR+ Cervical Squamous Cell Carcinoma the same as Non-Hodgkin Lymphoma? And so on.

Alfalfa and cancer

Alfalfa (Medicago sativa), also known as lucerne or purple medic, is a perennial herb belonging to the pea family. It has strong antioxidant properties. The seeds and dried leaves of Alfalfa are also available in the form of dietary supplements. Following are some of the potential health benefits of Alfalfa:

Alfalfa contains many active ingredients like 7-4′-dihydroxyflavone and Genistein at different concentrations. The molecular pathways which are regulated by Alfalfa include Stem Cell Signaling, PI3K-AKT-MTOR Signaling, Chemokine Signaling, Estrogen Signaling, Growth Factor Signaling, Lipid Metabolism and DNA Repair. These cellular pathways directly or indirectly influence cancer molecular endpoints like growth, spread and death. Because of this biological relationship – for cancer, choosing foods like Alfalfa and supplements is an important decision to be made. And not necessarily the same food choices are scientifically correct across individuals.

Include Alfalfa in Your Cancer Nutrition?

The answer to the question “Which Foods to Eat” and “Which Foods to Reduce Intake of” is It Depends!. Just like the same treatment does not work for every cancer patient, based on individual context the Alfalfa may have scientific benefits or have adverse interactions. Along with cancer  – the ongoing treatments, supplements, lifestyle habits, height, weight, allergies and food preferences are all factors influencing answers to the question. 

1. Continue Eating Alfalfa for Non-Hodgkin Lymphoma and Ifosfamide treatment?

Non-Hodgkin Lymphoma is defined and driven by specific genetic mutations like KMT2D and CREBBP leading to biochemical pathway changes in DNA Repair, PI3K-AKT-MTOR Signaling, P53 Signaling and Oncogenic Histone Methylation. A cancer treatment like Ifosfamide has molecular action on a unique set of biochemical pathways. The treatment intent is to have a good overlap between the cancer driving pathways and those manipulated by the treatment. In such conditions foods which have an opposing effect to the treatment and reduce the overlap between the cancer driving pathways and treatment should be avoided. As an example, Alfalfa intake should be reduced by cancer patients with Non-Hodgkin Lymphoma while on Ifosfamide treatment. Alfalfa impacts pathways or processes like DNA Repair which can negate the effects of the treatment. The factors to be considered when choosing foods and supplements are which cancer, treatments and supplements being taken currently, which age group, gender, height, weight, lifestyle habits and any genetic information.

2. Continue Eating Alfalfa for EGFR+ Cervical Squamous Cell Carcinoma and Bevacizumab treatment?

EGFR+ Cervical Squamous Cell Carcinoma is defined and driven by specific genetic mutations like EGFR and PIK3CA leading to biochemical pathway changes in PI3K-AKT-MTOR Signaling, Chemokine Signaling, Small Molecule Transport and MAPK Signaling. A cancer treatment like Bevacizumab has molecular action on a unique set of biochemical pathways. Alfalfa should be considered by cancer patients with EGFR+ Cervical Squamous Cell Carcinoma while on Bevacizumab treatment. Alfalfa impacts pathways or processes like PI3K-AKT-MTOR Signaling and Chemokine Signaling which can either obstruct drivers of EGFR+ Cervical Squamous Cell Carcinoma and/or improve Bevacizumab treatment effect.

For which cancers should Alfalfa be avoided

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

3. Continue Eating Alfalfa for RAD50 Associated Cancer Genetic Risk? 

Many companies offer gene panels testing for evaluating genetic risk to different cancers. These panels cover genes associated with high prevalence cancers of breast, ovary, uterus, prostate and gastrointestinal system and others. Testing of these genes may confirm a diagnosis or identify risk to some cancers. RAD50 is one of the genes available in panels for cancer risk testing. 

RAD50 mutation causes biochemical pathways or processes like Estrogen Signaling, Stem Cell Signaling, Growth Factor Signaling, DNA Repair and Angiogenesis to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Alfalfa should be reduced when mutation of RAD50 for risk of Breast Cancer is identified. Alfalfa impacts pathways or processes like Estrogen Signaling and Stem Cell Signaling and creates adverse effects with RAD50 mutation and related conditions.

4. Continue Eating Alfalfa for AXIN2 Associated Cancer Genetic Risk? 

AXIN2 is also one of many genes available in panels for cancer risk testing. AXIN2 mutation causes biochemical pathways or processes like Growth Factor Signaling, Lipid Metabolism, Stem Cell Signaling, MYC Signaling and WNT Betacatenin Signaling to get impacted. These pathways are direct or indirect drivers of cancer molecular endpoints. Intake of foods like Alfalfa should be considered when mutation of AXIN2 for risk of Colon Cancer is identified. Alfalfa impacts pathways or processes like Growth Factor Signaling and Lipid Metabolism and creates a supportive effect in those with AXIN2 mutation and related conditions.

* Other Factors Included Like BMI, Lifestyle Habits, Treatments

In Conclusion 

Nutrition for cancer (including supplements and foods like Alfalfa) and treatments may not be the same for everyone. 

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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