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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which Foods and Supplements to Avoid for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Oct 12, 2021

Estimated reading time: 9 minutes
Home » Blogs » Which Foods and Supplements to Avoid for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Highlights

No two cancers are the same and neither should your nutrition be. When diagnosed with cancer or at risk of cancer – one immediate question is “What Should I Eat Differently Starting Now?” and “Which Supplements Should I Take and Avoid”. The answer is “It Depends”. It depends on which genetic mutations your tests identified. It depends on which cancer, which ongoing treatments and supplements. It depends on your age, weight, height, lifestyle, allergies and habits. The answer to “What Should I Eat Differently” and “Which Supplements Should I Take and Avoid” for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC) also requires understanding of how the food and supplements included in your diet manipulate the molecular pathways which are relevant for cancer and interactions with your treatment.

Internet search to find answers will never be personalized to your cancer type such as NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC) and lifestyle conditions. Cancers are driven by biochemical pathways and therefore the answers to nutrition questions have to be based on molecular science irrespective of whether one understands it or not.  

For example foods like Tomato and Bamboo are recommended when undergoing Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC). But Black Chokeberry and Blueberry are recommended when treatment changes to Docetaxel. 

Similarly Alpha Lipoic Acid supplements are recommended with Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC). But Vitamin E supplements are recommended when treatment changes to Docetaxel. So always personalize your nutrition to your cancer gene mutations and other factors.



What is NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the different subtypes of Head and Neck Squamous Cell Carcinoma (HNSCC). In this subtype of HNSCC, a gene called NOTCH1 is either overexpressed or downregulated or mutated in the indication. The defects or aberrations or mutations in this gene can either drive cancer (tumor promoters) or remove brakes on cancer progression (tumor suppressors).  NOTCH gene mutations are prevalent in cancer Head and Neck Squamous Cell Carcinoma (HNSCC). You can visit NIH for information on the prevalence of genetic mutations across cancers. (Reference: Steven N Hart et al, Hum Mutat,. 2020

Diet for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)

Why Are Some Foods Recommended in the Diet for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Foods and Supplements contain different active ingredients which manipulate different molecular pathways relevant to cancers such as NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC). Genetic mutations and cancer conditions cause specific molecular pathways to become disrupted. Hence, those foods and supplements are recommended which do not disrupt those molecular pathways further and instead reverse the disruption. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), cancer pathways NFKB Signaling, Cell Cycle, MYC Signaling, Heat Stress Response, Apoptosis, Hypoxia, Glucocorticoid Signaling, Angiogenesis, Inflammation, Adherens junction, Chemokine Signaling, RAS-RAF Signaling, WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling, TGFB Signaling, Microtubule Dynamics, MAPK Signaling, Growth Factor Signaling, P53 Signaling, Cell Survival, Carbohydrate Metabolism, Nutrient sensing, Extracellular Matrix Remodelling, Epithelial to Mesenchymal Transition, JAK-STAT Signaling and Cytokine Signaling get disrupted. Choose those foods and supplements which contain active ingredients which cancel the molecular pathways disruption. Those supplements which interact with the treatments and disrupt the cancer molecular pathways further should be avoided.

The nutrition/diet for cancer such as NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC) depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. 

Example Foods to Eat with Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)

Foods and Supplements to take and avoid for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)

Recommended Foods

Tomato: Tomato contains active ingredients like Glucaric Acid, Citric Acid and Lupeol. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Glucaric Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Tomato are recommended as part of the diet along with treatment Paclitaxel for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Bamboo: Bamboo contains active ingredients like Beta-sitosterol, Citric Acid and Linoleic Acid. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Beta-sitosterol manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Bamboo are recommended as part of the diet along with treatment Paclitaxel for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Reduce Intake of These Foods

Yardlong Bean:  Yardlong Bean contains active ingredients like Folic Acid, Linoleic Acid and Oleic Acid. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Folic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Yardlong Bean when undergoing Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Jicama:  Jicama contains active ingredients like Retinol, Vitamin C and Folic Acid. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, TGFB Signaling is also disrupted and drives the cancer. Retinol manipulates the molecular pathways like TGFB Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Jicama when undergoing Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Which Supplements To Avoid with Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Unlike foods, supplements are high concentrations of active ingredients and hence important to understand the interactions with Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Silymarin: Silymarin contains active ingredients Silibinin. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Adherens junction and Apoptosis are also disrupted and drive the cancer. Silibinin manipulates the molecular pathways like Adherens junction and Apoptosis so as to disrupt them further. Hence avoid Silymarin supplements when undergoing Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Caffeine: For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Apoptosis and Adherens junction are also disrupted and drive the cancer. Caffeine manipulates the molecular pathways like Apoptosis and Adherens junction so as to disrupt them further. Hence avoid Caffeine supplements when undergoing Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Should I take this Nutritional Supplement with Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Alpha Lipoic Acid:  For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Adherens junction and Nutrient sensing are also disrupted and drive the cancer. Alpha Lipoic Acid manipulates the molecular pathways like Adherens junction and Nutrient sensing so as to cancel these disruptions. Hence Alpha Lipoic Acid supplements are recommended with Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Vitamin C:  For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Adherens junction and Nutrient sensing are also disrupted and drive the cancer. Vitamin C manipulates the molecular pathways like Adherens junction and Nutrient sensing so as to cancel these disruptions.  Hence Vitamin C supplements are recommended with Paclitaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

For NOTCH+ Head and Neck Squamous Cell Carcinoma avoid these foods and supplements!

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Example Foods to Eat with Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)

Recommended Foods

Black Chokeberry: Black Chokeberry contains active ingredients like Hyperoside, Caffeic Acid and Quercetin. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Hyperoside manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Black Chokeberry are recommended along with treatment Docetaxel for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Blueberry: Blueberry contains active ingredients like Caffeic Acid, Myricetin and Gallic Acid. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Caffeic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Blueberry are recommended along with treatment Docetaxel for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Reduce Intake of These Foods

Kumquat:  Kumquat contains active ingredients like Apigenin, Naringenin and Linoleic Acid. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, TGFB Signaling is also disrupted and drives the cancer. Apigenin manipulates the molecular pathways like TGFB Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Kumquat when undergoing Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Acorn:  Acorn contains active ingredients like Folic Acid and Retinol. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Folic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Acorn when undergoing Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Which Supplements To Avoid with Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Unlike foods, supplements are high concentrations of active ingredients and hence important to understand the interactions with Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Fennel:  Fennel contains active ingredients Anethole, Apiole and Caffeic Acid. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Adherens junction and Apoptosis are also disrupted and drive the cancer. Anethole manipulates the molecular pathways like Adherens junction and Apoptosis so as to disrupt them further. Hence avoid Fennel supplements when undergoing Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Pineapple:  Pineapple contains active ingredients Beta-sitosterol, Ergosterol Peroxide and Ferulic Acid. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Adherens junction and Nutrient sensing are also disrupted and drive the cancer. Beta-sitosterol manipulates the molecular pathways like Adherens junction and Nutrient sensing so as to disrupt them further. Hence avoid Pineapple supplements when undergoing Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Should I take this Nutritional Supplement with Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC)?

Vitamin E:  For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Apoptosis and Angiogenesis are also disrupted and drive the cancer. Vitamin E manipulates the molecular pathways like Apoptosis and Angiogenesis so as to cancel these disruptions. Hence Vitamin E supplements are recommended with Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

Ashwagandha:  Ashwagandha contains active ingredients Withaferin A. For NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC), along with other pathways, Nutrient sensing and Apoptosis are also disrupted and drive the cancer. Withaferin A manipulates the molecular pathways like Nutrient sensing and Apoptosis so as to cancel these disruptions.  Hence Ashwagandha supplements are recommended with Docetaxel treatment for NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

In Conclusion

Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as NOTCH+ Head and Neck Squamous Cell Carcinoma (HNSCC).

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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