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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which Foods and Supplements to Avoid for NF1+ Melanoma?

Oct 4, 2021

Estimated reading time: 6 minutes
Home » Blogs » Which Foods and Supplements to Avoid for NF1+ Melanoma?

Highlights

No two cancers are the same and neither should your nutrition be. When diagnosed with cancer or at risk of cancer – one immediate question is “What Should I Eat Differently Starting Now?” and “Which Supplements Should I Take and Avoid”. The answer is “It Depends”. It depends on which genetic mutations your tests identified. It depends on which cancer, which ongoing treatments and supplements. It depends on your age, weight, height, lifestyle, allergies and habits. The answer to “What Should I Eat Differently” and “Which Supplements Should I Take and Avoid” for NF1+ Melanoma also requires understanding of how the food and supplements included in your diet manipulate the molecular pathways which are relevant for cancer and interactions with your treatment.

Internet search to find answers will never be personalized to your cancer type such as NF1+ Melanoma and lifestyle conditions. Cancers are driven by biochemical pathways and therefore the answers to nutrition questions have to be based on molecular science irrespective of whether one understands it or not.  

For example foods like Tomato and Squash are recommended when undergoing Cobimetinib treatment for NF1+ Melanoma. Similarly Alpha Lipoic Acid supplements are recommended with Cobimetinib treatment for NF1+ Melanoma. So always personalize your nutrition to your cancer gene mutations and other factors.



What is NF1+ Melanoma?

NF1+ Melanoma is one of the different subtypes of Melanoma. In this subtype, a gene called NF1 is either mutated or overexpressed. The defects or aberrations or mutations in these genes can either drive cancer (tumor promoters) or remove brakes on cancer progression (tumor suppressors).  NF1 gene mutations are prevalent in cancer- Melanoma. You can visit NIH for information on the prevalence of genetic mutations across cancers. (Reference: Steven N Hart et al, Hum Mutat,. 2020

Diet for NF1+ Melanoma

Why Are Some Foods Recommended in the Diet for NF1+ Melanoma?

Foods and Supplements contain different active ingredients which manipulate different molecular pathways relevant to cancers such as NF1+ Melanoma. Genetic mutations and cancer conditions cause specific molecular pathways to become disrupted. Hence, those foods and supplements are recommended which do not disrupt those molecular pathways further and instead reverse the disruption. For NF1+ Melanoma, cancer pathways Amino Acid Metabolism, MYC Signaling, Adherens junction, DNA Repair, Epithelial to Mesenchymal Transition, WNT Beta Catenin Signaling, RAS-RAF Signaling, Extracellular Matrix Remodelling, Focal Adhesion, PI3K-AKT-MTOR Signaling, TGFB Signaling, JAK-STAT Signaling, MAPK Signaling, Vitamin D Signaling, Growth Factor Signaling, Angiogenesis and Small Molecule Transport get disrupted. Choose those foods and supplements which contain active ingredients which cancel the molecular pathways disruption. Those supplements which interact with the treatments and disrupt the cancer molecular pathways further should be avoided.

The nutrition/diet for cancer such as NF1+ Melanoma depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. 

Example Foods to Eat with Cobimetinib treatment for NF1+ Melanoma

Foods and Supplements to take and avoid for NF1+ Melanoma

Recommended Foods

Tomato: Tomato contains active ingredients like Glucaric Acid, Citric Acid and Lupeol. For NF1+ Melanoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Glucaric Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Tomato are recommended along with treatment Cobimetinib for NF1+ Melanoma.

Squash: Squash contains active ingredients like Beta-sitosterol, Citric Acid and Ellagic Acid. For NF1+ Melanoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Beta-sitosterol manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Squash are recommended along with treatment Cobimetinib for NF1+ Melanoma.

Reduce Intake of These Foods

Arugula:  Arugula contains active ingredients like Kaempferol, Esculin and Erysolin. For NF1+ Melanoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Kaempferol manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Arugula when undergoing Cobimetinib treatment for NF1+ Melanoma.

Yardlong Bean:  Yardlong Bean contains active ingredients like Folic Acid, Linoleic Acid and Oleic Acid. For NF1+ Melanoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Folic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Yardlong Bean when undergoing Cobimetinib treatment for NF1+ Melanoma.

For NF1+ Melanoma avoid these foods and supplements!

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Which Supplements To Avoid with Cobimetinib treatment for NF1+ Melanoma?

Unlike foods, supplements are high concentrations of active ingredients and hence important to understand the interactions with Cobimetinib treatment for NF1+ Melanoma.

Silymarin: Silymarin contains active ingredients Silibinin. For NF1+ Melanoma, along with other pathways, Adherens junction and DNA Repair are also disrupted and drive the cancer. Silibinin manipulates the molecular pathways like Adherens junction and DNA Repair so as to disrupt them further. Hence avoid Silymarin supplements when undergoing Cobimetinib treatment for NF1+ Melanoma.

Caffeine: For NF1+ Melanoma, along with other pathways, Adherens junction and Vitamin D Signaling are also disrupted and drive the cancer. Caffeine manipulates the molecular pathways like Adherens junction and Vitamin D Signaling so as to disrupt them further. Hence avoid Caffeine supplements when undergoing Cobimetinib treatment for NF1+ Melanoma.

Should I take this Nutritional Supplement with Cobimetinib treatment for NF1+ Melanoma?

Alpha Lipoic Acid:  For NF1+ Melanoma, along with other pathways, Adherens junction and WNT Beta Catenin Signaling are also disrupted and drive the cancer. Alpha Lipoic Acid manipulates the molecular pathways like Adherens junction and WNT Beta Catenin Signaling so as to cancel these disruptions. Hence Alpha Lipoic Acid supplements are recommended with Cobimetinib treatment for NF1+ Melanoma.

Vitamin C:  For NF1+ Melanoma, along with other pathways, Adherens junction and Vitamin D Signaling are also disrupted and drive the cancer. Vitamin C manipulates the molecular pathways like Adherens junction and Vitamin D Signaling so as to cancel these disruptions.  Hence Vitamin C supplements are recommended with Cobimetinib treatment for NF1+ Melanoma.

In Conclusion

Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as NF1+ Melanoma.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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