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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which Foods and Supplements to Avoid for BAP1+ Cholangiocarcinoma?

Aug 31, 2021

Estimated reading time: 8 minutes
Home » Blogs » Which Foods and Supplements to Avoid for BAP1+ Cholangiocarcinoma?

Highlights

No two cancers are the same and neither should your nutrition be. When diagnosed with cancer or at risk of cancer – one immediate question is “What Should I Eat Differently Starting Now?” and “Which Supplements Should I Take and Avoid”. The answer is “It Depends”. It depends on which genetic mutations your tests identified. It depends on which cancer, which ongoing treatments and supplements. It depends on your age, weight, height, lifestyle, allergies and habits. The answer to “What Should I Eat Differently” and “Which Supplements Should I Take and Avoid” for BAP1+ Cholangiocarcinoma also requires understanding of how the food and supplements included in your diet manipulate the molecular pathways which are relevant for cancer and interactions with your treatment.

Internet search to find answers will never be personalized to your cancer type such as BAP1+ Cholangiocarcinoma and lifestyle conditions. Cancers are driven by biochemical pathways and therefore the answers to nutrition questions have to be based on molecular science irrespective of whether one understands it or not.  

For example foods like Bamboo and Bottle Gourd are recommended when undergoing Cisplatin treatment for BAP1+ Cholangiocarcinoma. But Quinoa and Galangal are recommended when treatment changes to Gemcitabine. 

Similarly Tangerine supplements are recommended with Cisplatin treatment for BAP1+ Cholangiocarcinoma. But Caffeine supplements are recommended when treatment changes to Gemcitabine. So always personalize your nutrition to your cancer gene mutations and other factors.



What is BAP1+ Cholangiocarcinoma?

BAP1+ Cholangiocarcinoma is one of the different subtypes of Cholangiocarcinoma. In this subtype of Cholangiocarcinoma, mutation of a gene called BAP1 is detected. The defects or aberrations or mutations in these genes can either drive cancer (tumor promoters) or remove brakes on cancer progression (tumor suppressors).  BAP1 gene mutations are prevalent in cancer Cholangiocarcinoma. You can visit NIH for information on the prevalence of genetic mutations across cancers. (Reference: Steven N Hart et al, Hum Mutat,. 2020)

Diet for BAP1+ Cholangiocarcinoma

Why Are Some Foods Recommended in the Diet for BAP1+ Cholangiocarcinoma?

Foods and Supplements contain different active ingredients which manipulate different molecular pathways relevant to cancers such as BAP1+ Cholangiocarcinoma. Genetic mutations and cancer conditions cause specific molecular pathways to become disrupted. Hence, those foods and supplements are recommended which do not disrupt those molecular pathways further and instead reverse the disruption. For BAP1+ Cholangiocarcinoma, cancer pathways or processes like NFKB Signaling, MYC Signaling, Hypoxia, Angiogenesis, Lipid Metabolism, Adherens junction, DNA Repair, WNT Beta Catenin Signaling, Endoplasmic Reticulum Stress, Focal Adhesion, Replication Stress, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, TGFB Signaling, Notch Signaling, MAPK Signaling, Growth Factor Signaling, P53 Signaling, Netrin Signaling, Nucleotide metabolism, RUNX Signaling, Epithelial to Mesenchymal Transition, Oxidative Stress, JAK-STAT Signaling and Hedgehog Signaling get disrupted. Choose those foods and supplements which contain active ingredients which cancel the molecular pathways disruption. Those supplements which interact with the treatments and disrupt the cancer molecular pathways further should be avoided.

The nutrition/diet for cancer such as BAP1+ Cholangiocarcinoma depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. 

Example Foods to Eat with Cisplatin treatment for BAP1+ Cholangiocarcinoma

Foods and Supplements to take and avoid for BAP1+ Cholangiocarcinoma

Recommended Foods

Bamboo: Bamboo contains active ingredients like Beta-sitosterol, Citric Acid and Linoleic Acid. For BAP1+ Cholangiocarcinoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Beta-sitosterol manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Bamboo are recommended along with treatment Cisplatin for BAP1+ Cholangiocarcinoma.

Bottle Gourd: Bottle Gourd contains active ingredients like Vitamin C, Citric Acid and Linoleic Acid. For BAP1+ Cholangiocarcinoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Vitamin C manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Bottle Gourd are recommended along with treatment Cisplatin for BAP1+ Cholangiocarcinoma.

Reduce Intake of These Foods

Spinach:  Spinach contains active ingredients like Citric Acid, Linoleic Acid and Folic Acid. For BAP1+ Cholangiocarcinoma, along with other pathways, MAPK Signaling is also disrupted and drives the cancer. Citric Acid manipulates the molecular pathways like MAPK Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Spinach when undergoing Cisplatin treatment for BAP1+ Cholangiocarcinoma.

Radish:  Radish contains active ingredients like Folic Acid, Citric Acid and Vitamin B3. For BAP1+ Cholangiocarcinoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Folic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Radish when undergoing Cisplatin treatment for BAP1+ Cholangiocarcinoma.

Which Supplements To Avoid with Cisplatin treatment for BAP1+ Cholangiocarcinoma?

Unlike foods, supplements are high concentrations of active ingredients and hence important to understand the interactions with Cisplatin treatment for BAP1+ Cholangiocarcinoma.

Feverfew: Feverfew contains active ingredients Centaureidin and Parthenolide. For BAP1+ Cholangiocarcinoma, along with other pathways, Oxidative Stress and Cell Cycle are also disrupted and drive the cancer. Centaureidin manipulates the molecular pathways like Oxidative Stress and Cell Cycle so as to disrupt them further. Hence avoid Feverfew supplements in diet when undergoing Cisplatin treatment for BAP1+ Cholangiocarcinoma.

Black Seed: Black Seed contains active ingredients Carvacrol, Thymol and Thymoquinone. For BAP1+ Cholangiocarcinoma, along with other pathways, Cell Cycle Checkpoints and Oxidative Stress are also disrupted and drive the cancer. Carvacrol manipulates the molecular pathways like Cell Cycle Checkpoints and Oxidative Stress so as to disrupt them further. Hence avoid Black Seed supplements in diet when undergoing Cisplatin treatment for BAP1+ Cholangiocarcinoma.

Should I take this Nutritional Supplement with Cisplatin treatment for BAP1+ Cholangiocarcinoma?

Tangerine:  Tangerine contains active ingredients Nobiletin and Tangeretin. For BAP1+ Cholangiocarcinoma, along with other pathways, Cell Cycle Checkpoints and P53 Signaling  are also disrupted and drive the cancer. Nobiletin manipulates the molecular pathways like Cell Cycle Checkpoints and P53 Signaling so as to cancel these disruptions. Hence Tangerine supplements are recommended with Cisplatin treatment for BAP1+ Cholangiocarcinoma.

Curcumin:  For BAP1+ Cholangiocarcinoma, along with other pathways, Cell Cycle Checkpoints and Oxidative Stress are also disrupted and drive the cancer. Curcumin manipulates the molecular pathways like Cell Cycle Checkpoints and Oxidative Stress so as to cancel these disruptions.  Hence Curcumin supplements are recommended with Cisplatin treatment for BAP1+ Cholangiocarcinoma.

Example Foods to Eat with Gemcitabine treatment for BAP1+ Cholangiocarcinoma

Recommended Foods

Quinoa: Quinoa contains active ingredients like Protocatechuic Acid, Linoleic Acid and Folic Acid. For BAP1+ Cholangiocarcinoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Protocatechuic Acid manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Quinoa are recommended along with treatment Gemcitabine for BAP1+ Cholangiocarcinoma.

Galangal: Galangal contains active ingredients like Galangin, Myricetin and Kaempferide. For BAP1+ Cholangiocarcinoma, along with other pathways, PI3K-AKT-MTOR Signaling is also disrupted and drives the cancer. Galangin manipulates the molecular pathways like PI3K-AKT-MTOR Signaling so as to cancel the disruption. Hence, foods like Galangal are recommended along with treatment Gemcitabine for BAP1+ Cholangiocarcinoma.

Reduce Intake of These Foods

Kumquat:  Kumquat contains active ingredients like Naringetol, Naringenin and Linoleic Acid. For BAP1+ Cholangiocarcinoma, along with other pathways, WNT Betacatenin Signaling is also disrupted and drives the cancer. Naringetol manipulates the molecular pathways like WNT Betacatenin Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Kumquat when undergoing Gemcitabine treatment for BAP1+ Cholangiocarcinoma.

Tarragon:  Tarragon contains active ingredients like Kaempferol, Eucalyptol and Rutin. For BAP1+ Cholangiocarcinoma, along with other pathways, MAPK Signaling is also disrupted and drives the cancer. Kaempferol manipulates the molecular pathways like MAPK Signaling so as to disrupt them further. Hence avoid or reduce the intake of foods like Tarragon when undergoing Gemcitabine treatment for BAP1+ Cholangiocarcinoma.

Nutrition while on Chemotherapy | Personalized to Individual's Cancer type, Lifestyle & Genetics

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

Which Supplements To Avoid with Gemcitabine treatment for BAP1+ Cholangiocarcinoma?

Unlike foods, supplements are high concentrations of active ingredients and hence important to understand the interactions with Gemcitabine treatment for BAP1+ Cholangiocarcinoma.

Fava Bean:  Fava Bean contains active ingredients Astragalin, Beta-sitosterol and Betulin. For BAP1+ Cholangiocarcinoma, along with other pathways, Oxidative Stress and MAPK Signaling are also disrupted and drive the cancer. Astragalin manipulates the molecular pathways like Oxidative Stress and MAPK Signaling so as to disrupt them further. Hence avoid Fava Bean supplements when undergoing Gemcitabine treatment for BAP1+ Cholangiocarcinoma.

Fennel:  Fennel contains active ingredients Anethole, Apiole and Caffeic Acid. For BAP1+ Cholangiocarcinoma, along with other pathways, Adherens junction and P53 Signaling are also disrupted and drive the cancer. Anethole manipulates the molecular pathways like Adherens junction and P53 Signaling so as to disrupt them further. Hence avoid Fennel supplements when undergoing Gemcitabine treatment for BAP1+ Cholangiocarcinoma.

Should I take this Nutritional Supplement with Gemcitabine treatment for BAP1+ Cholangiocarcinoma?

Caffeine:  For BAP1+ Cholangiocarcinoma, along with other pathways, Endoplasmic Reticulum Stress and P53 Signaling are also disrupted and drive the cancer. Caffeine manipulates the molecular pathways like Endoplasmic Reticulum Stress and P53 Signaling so as to cancel these disruptions. Hence Caffeine supplements are recommended with Gemcitabine treatment for BAP1+ Cholangiocarcinoma.

Skullcap:  Skullcap contains active ingredients Baicalein, Oroxylin A and Scutellarein. For BAP1+ Cholangiocarcinoma, along with other pathways, Oxidative Stress and NFKB Signaling are also disrupted and drive the cancer. Baicalein manipulates the molecular pathways like Oxidative Stress and NFKB Signaling so as to cancel these disruptions.  Hence Skullcap supplements are recommended with Gemcitabine treatment for BAP1+ Cholangiocarcinoma.

In Conclusion

Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as BAP1+ Cholangiocarcinoma.

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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