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What should I eat after Cancer Diagnosis?

is a very common question asked.​
Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

is a very common question asked. Choose food and supplements personalized to your cancer, genes, ongoing treatments and lifestyle.

Personalized cancer Nutrition Planning for only .

Personalized cancer Nutrition Planning for only​ .

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Which 3 Foods to Avoid for Diffuse Large B-Cell Lymphoma (DLBCL)?

Aug 26, 2021

Estimated reading time: 7 minutes
Home » Blogs » Which 3 Foods to Avoid for Diffuse Large B-Cell Lymphoma (DLBCL)?

Highlights

No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Diffuse Large B-Cell Lymphoma (DLBCL) needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.

Foods like Ajwain and Aloe Vera should be eaten when undergoing Cyclophosphamide treatment for Diffuse Large B-Cell Lymphoma (DLBCL). On the same lines, avoid foods like Acorn and Black-eyed Pea with treatment of Cyclophosphamide for Diffuse Large B-Cell Lymphoma (DLBCL). Also, Black Seed supplements contain an active ingredient called Thymoquinone. Thymoquinone has CYP (drug metabolizing enzyme) interactions with Cyclophosphamide treatment and hence should be avoided.

You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Diffuse Large B-Cell Lymphoma (DLBCL).



What is Diffuse Large B-Cell Lymphoma (DLBCL)?

Diffuse Large B-Cell Lymphoma (DLBCL) is the most common type of Non-Hodgkin lymphoma cancer that starts in white blood cells called lymphocytes. The incidence rate of this cancer is only 5.6 per 1 lakh people per year. This cancer is commonly diagnosed in people who are above 65 years of age, however, it can occur in people of any age. It is slightly more commonly found in males as compared to females.

Symptoms, Treatment and Diet for Diffuse Large B-Cell Lymphoma (DLBCL)

Diffuse Large B-Cell Lymphoma (DLBCL) has prevalence of certain genetic changes. Some of the genes such as KMT2D, B2M, CARD11, and PIM1 are known to have genetic abnormalities in this cancer resulting in a change of function. 

The genetic abnormalities found in Diffuse Large B-Cell Lymphoma (DLBCL) can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment.  In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Diffuse Large B-Cell Lymphoma (DLBCL). Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Diffuse Large B-Cell Lymphoma (DLBCL) genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing a diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Diffuse Large B-Cell Lymphoma (DLBCL) nutrition may have to be redesigned.

Why Eating Right Matters for Diffuse Large B-Cell Lymphoma (DLBCL)?

In Diffuse Large B-Cell Lymphoma (DLBCL), activation or inhibition of some of the biochemical pathways including WNT Beta Catenin Signaling, MYC Signaling, MAPK Signaling, Hypoxia, Cell Cycle Checkpoints, Cancer Epigenetics, Hippo Signaling, Small Molecule Transport, P53 Signaling, NFKB Signaling, Vitamin D Signaling, PI3K-AKT-MTOR Signaling, Oxidative Stress, Amino Acid Metabolism, Apoptosis, Heat Stress Response, DNA Repair and Epithelial To Mesenchymal Transition plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Diffuse Large B-Cell Lymphoma (DLBCL), eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.

Example Foods to “Not Eat” and Eat with Cyclophosphamide treatment for Diffuse Large B-Cell Lymphoma (DLBCL)

The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Diffuse Large B-Cell Lymphoma (DLBCL) considering only one specific treatment – Cyclophosphamide.

Foods to eat and avoid for Diffuse Large B-Cell Lymphoma (DLBCL).

Foods to Avoid

Acorn : Acorn contains active ingredients such as Folic Acid, Retinol and others. Folic Acid interferes with the impact of Cyclophosphamide in Diffuse Large B-Cell Lymphoma (DLBCL) by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Acorn with Cyclophosphamide treatment for Diffuse Large B-Cell Lymphoma (DLBCL). 

Black-eyed Pea : Black-eyed Pea contains active ingredients such as Genistein, Folic Acid, Retinol and others. Genistein interferes with the impact of Cyclophosphamide in Diffuse Large B-Cell Lymphoma (DLBCL) by activating a specific biochemical pathway called Hippo Signaling. Hence, avoid foods like Black-eyed Pea with Cyclophosphamide treatment for Diffuse Large B-Cell Lymphoma (DLBCL).

Foods to Eat

Ajwain :  Ajwain contains active ingredients like Chlorogenic Acid, Stigmasterol and Oleic Acid. Intake of Chlorogenic Acid along with Cyclophosphamide treatment for Diffuse Large B-Cell Lymphoma (DLBCL) causes a decrease in a specific biochemical pathway which is called  PI3K-AKT-MTOR Signaling, and this is a very positive effect. Ajwain hence should be eaten with Cyclophosphamide treatment for Diffuse Large B-Cell Lymphoma (DLBCL). (Xiaokang Wang et al, J Pharm Pharmacol., 2019; Zi-Zhen Xu et al, Ann Hematol., 2013)

Aloe Vera :  Aloe Vera contains active ingredients like Lupeol, Acemannan and Barbaloin. Intake of Lupeol along with Cyclophosphamide treatment for Diffuse Large B-Cell Lymphoma (DLBCL) causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Aloe Vera hence should be eaten with Cyclophosphamide treatment for Diffuse Large B-Cell Lymphoma (DLBCL). (Lingli Zhang et al, Eur J Pharmacol., 2015; Zi-Zhen Xu et al, Ann Hematol., 2013)

Should I take this Nutritional Supplement for Diffuse Large B-Cell Lymphoma (DLBCL)?

Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 interactions with Cyclophosphamide treatment, and hence should not be used. Also, Black Seed supplement interferes with the impact of Cyclophosphamide in Diffuse Large B-Cell Lymphoma (DLBCL) by increasing pathways like Vitamin Metabolism. 

Nutrition while on Chemotherapy | Personalized to Individual's Cancer type, Lifestyle & Genetics

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.

What are the Symptoms of Diffuse Large B-Cell Lymphoma (DLBCL)?

In the initial stages, most cancers including Diffuse Large B-Cell Lymphoma (DLBCL) may not cause any signs or symptoms. However, as the disease progresses, Diffuse Large B-Cell Lymphoma (DLBCL) may start showing symptoms. 

Following are some of the signs and symptoms that may be caused by Diffuse Large B-Cell Lymphoma (DLBCL).

  • Breathlessness
  • Bone pain
  • Pain in the chest or abdomen
  • Lumps on the skin
  • Cough

Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Diffuse Large B-Cell Lymphoma (DLBCL).

What are the Treatment Options for Diffuse Large B-Cell Lymphoma (DLBCL)?

The treatment for Diffuse Large B-Cell Lymphoma (DLBCL) may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, and whether the cancer was just diagnosed or had come back. The treatment options for Diffuse Large B-Cell Lymphoma (DLBCL) include:

  • Chemotherapy
  • Chemoimmunotherapy
  • Radiotherapy
  • Autologous stem cell transplant

As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Diffuse Large B-Cell Lymphoma (DLBCL).

In Conclusion

The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Diffuse Large B-Cell Lymphoma (DLBCL).

What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.

The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.

Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.

Foods to Eat After Cancer Diagnosis!

No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.


Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.


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