No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Diffuse Glioma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Ajwain and Avocado should be eaten when undergoing Procarbazine treatment for Diffuse Glioma. On the same lines, foods like Anise and Arrowroot should be avoided with treatment of Procarbazine for Diffuse Glioma.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Diffuse Glioma.
What is Diffuse Glioma?
Diffuse Glioma refers to different types of tumors of the central nervous system with histological similarity to glial cells, especially astrocytoma, oligodendroglioma and oligoastrocytoma, ranging from WHO grade II to grade IV tumors. The incidence rate of this cancer is only 6 per 1 lakh people per year. It is slightly more commonly found in males as compared to females.
Diffuse Glioma has prevalence of certain genetic changes. Some of the genes such as IDH1, MGMT, TP53, and ATRX are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Diffuse Glioma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Diffuse Glioma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Diffuse Glioma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Diffuse Glioma nutrition may have to be redesigned.
Why Eating Right Matters for Diffuse Glioma?
In Diffuse Glioma, activation or inhibition of some of the biochemical pathways including Wnt Beta Catenin Signaling, MYC Signaling, Inflammation, MAPK Signaling, Hypoxia, Cell Cycle Checkpoints, Cell Cycle, Cancer Epigenetics, Notch Signaling, PI3K-AKT-MTOR Signaling, Carbohydrate Metabolism, NFKB Signaling, Apoptosis, Endoplasmic Reticulum Stress, DNA Repair and Epithelial To Mesenchymal Transition plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Diffuse Glioma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Procarbazine treatment for Diffuse Glioma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Diffuse Glioma considering only one specific treatment – Procarbazine.
Foods to Avoid with Procarbazine treatment
Anise : Anise contains active ingredients such as Apigenin, Vitamin C, D-limonene and others. Apigenin interferes with the impact of Procarbazine in Diffuse Glioma by activating a specific biochemical pathway called DNA Repair. Hence, do not eat Anise with Procarbazine treatment for Diffuse Glioma.
Arrowroot : Arrowroot contains active ingredients such as Beta-carotene, Vitamin C, Quercetin and others. Beta-carotene interferes with the impact of Procarbazine in Diffuse Glioma by activating a specific biochemical pathway called Notch Signaling. Hence, do not eat Arrowroot with Procarbazine treatment for Diffuse Glioma.
Foods to Eat with Procarbazine treatment
Ajwain : Ajwain contains active ingredients like Stigmasterol, Oleic Acid and Methoxsalen. Intake of Stigmasterol along with Procarbazine treatment for Diffuse Glioma causes a decrease in a specific biochemical pathway which is called DNA Repair, and this is a very positive effect. Ajwain hence should be eaten with Procarbazine treatment for Diffuse Glioma. (V S Prakash Chaturvedula et al, J Nat Prod., 2003; K Cornetta et al, Cancer Gene Ther., 2006)
Avocado : Avocado contains active ingredients like Quercetin, Vitamin C and Oleic Acid. Intake of Quercetin along with Procarbazine treatment for Diffuse Glioma causes a decrease in a specific biochemical pathway which is called Hypoxia, and this is a very positive effect. Avocado hence should be eaten with Procarbazine treatment for Diffuse Glioma. (Hak-Su Kim et al, Apoptosis., 2012; K Cornetta et al, Cancer Gene Ther., 2006)
Should I take this Nutritional Supplement with Procarbazine treatment?
Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Procarbazine treatment. Black Seed supports the Procarbazine treatment for Diffuse Glioma by decreasing the biochemical pathways such as MAPK Signaling, NFKB Signaling, Notch Signaling and PI3K-AKT-MTOR Signaling, and increasing pathways/processes like Oxidative Stress.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of Diffuse Glioma?
In the initial stages, most cancers including Diffuse Glioma may not cause any signs or symptoms. However, as the disease progresses, Diffuse Glioma may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Diffuse Glioma.
- Abnormal eye movement
- Weakness on one side of the face
- Numbness of the extremities
- Difficulty balancing
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Diffuse Glioma.
What are the Treatment Options for Diffuse Glioma?
The treatment for Diffuse Glioma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Diffuse Glioma include:
Surgery or surgery followed by radiation is the most common treatment regimen for Diffuse Glioma. As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Diffuse Glioma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Diffuse Glioma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.