No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Basal Cell Carcinoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Aloe Vera and Bamboo should be eaten when undergoing Vismodegib treatment for Basal Cell Carcinoma. On the same lines, avoid foods like Black-eyed Pea and Carob with treatment of Vismodegib for Basal Cell Carcinoma.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Basal Cell Carcinoma.
What is Basal Cell Carcinoma?
Basal Cell Carcinoma is a type of skin cancer that develops from a type of cell within the skin which produces new skin cells and replaces the old ones that die off. The incidence rate of this cancer is 525 per 1 lakh people per year. This cancer is commonly diagnosed in people who are about 64 years of age, however, it can occur in people of any age. It is commonly found in common cancer in Caucasians, Hispanics, Chinese, and Japanese, and other Asian populations.
Basal Cell Carcinoma has prevalence of certain genetic changes. Some of the genes such as PTCH1, CSMD3, CSMD1, and LRP1B are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Basal Cell Carcinoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Basal Cell Carcinoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Basal Cell Carcinoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Basal Cell Carcinoma nutrition may have to be redesigned.
Why Eating Right Matters for Basal Cell Carcinoma?
In Basal Cell Carcinoma, activation or inhibition of some of the biochemical pathways including MYC Signaling, MAPK Signaling, Small Molecule Transport, Cell Cycle, RAS-RAF Signaling, Vitamin D Signaling, PI3K-AKT-MTOR Signaling, Nutrient Sensing and Oxidative Stress plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Basal Cell Carcinoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Vismodegib treatment for Basal Cell Carcinoma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Basal Cell Carcinoma considering only one specific treatment- Vismodegib.
Foods to Avoid
Black-eyed Pea : Black-eyed Pea contains active ingredients such as Genistein, Folic Acid, Retinol and others. Genistein interferes with the impact of Vismodegib in Basal Cell Carcinoma by blocking a specific biological process called Nutrient sensing. Hence, avoid foods like Black-eyed Pea with Vismodegib treatment for Basal Cell Carcinoma.
Carob : Carob contains active ingredients such as Palmitic Acid, Quercetin, Folic Acid and others. Palmitic Acid interferes with the impact of Vismodegib in Basal Cell Carcinoma by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Carob with Vismodegib treatment for Basal Cell Carcinoma.
Foods to Eat
Aloe Vera : Aloe Vera contains active ingredients like Barbaloin, Acemannan and Lupeol. Intake of Barbaloin along with Vismodegib treatment for Basal Cell Carcinoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Aloe Vera hence should be eaten with Vismodegib treatment for Basal Cell Carcinoma. (Ziqian Wang et al, Drug Des Devel Ther., 2020; Arianna L Kim et al, J Invest Dermatol., 2018)
Bamboo : Bamboo contains active ingredients like Tricin, Vitamin C and Oleic Acid. Intake of Tricin along with Vismodegib treatment for Basal Cell Carcinoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Bamboo hence should be eaten with Vismodegib treatment for Basal Cell Carcinoma. (Dai-Jung Chung et al, J Agric Food Chem., 2018; Arianna L Kim et al, J Invest Dermatol., 2018)
Should I take this Nutritional Supplement for Basal Cell Carcinoma?
Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Vismodegib treatment. Black Seed supports the Vismodegib treatment for Basal Cell Carcinoma by decreasing the biochemical pathways such as MAPK Signaling, Cell Cycle, MYC Signaling, PI3K-AKT-MTOR Signaling, Inositol Phosphate Signaling, Oxidative Stress, Cancer Epigenetics and RAS-RAF Signaling and increasing pathways like Nutrient sensing.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of Basal Cell Carcinoma?
As the disease progresses, Basal Cell Carcinoma may start showing symptoms. Following are some of the signs and symptoms that may be caused by Basal Cell Carcinoma.
- Scar-like flat, firm, pale or yellow areas
- Itchy raised reddish patches
- Small, pink/red, translucent, shiny, pearly bumps with possibly blue/brown/black areas
- Pink growths with raised edges with abnormal blood vessels spreading out like the spokes of a wheel
- Open sores
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Basal Cell Carcinoma.
What are the Treatment Options for Basal Cell Carcinoma?
The treatment for Basal Cell Carcinoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, whether the cancer can be removed completely by surgery and whether the cancer was just diagnosed or had come back. The treatment options for Basal Cell Carcinoma include:
- Radiation therapy
- Targeted drug therapy
- Photodynamic therapy
- Prescription creams or ointments
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Basal Cell Carcinoma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Basal Cell Carcinoma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.