No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Acute Lymphoid Leukemia needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Almond and Bayberry should be eaten when undergoing Cytarabine treatment for Acute Lymphoid Leukemia. On the same lines, avoid foods like Adzuki Bean and Black-eyed Pea with treatment of Cytarabine for Acute Lymphoid Leukemia (ALL).
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Acute Lymphoid Leukemia.
What is Acute Lymphoid Leukemia?
Acute Lymphoid Leukemia is a blood cancer that develops from white blood cells called lymphocytes. The incidence rate of this cancer is only 0.4 to 2 per 1 lakh people per year in Asia-Pacific and South American countries. This cancer is commonly diagnosed in children who are under 5 years of age and in adults over 50 years of age, however, it can occur in people of any age. It is more commonly found in Hispanic children and white children as compared to Asian children and Black children.
Acute Lymphoid Leukemia has prevalence of certain genetic changes. Some of the genes such as NRAS, KRAS, CREBBP, and PTPN11 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Acute Lymphoid Leukemia can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Acute Lymphoid Leukemia. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Acute Lymphoid Leukemia (ALL) genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Acute Lymphoid Leukemia nutrition may have to be redesigned.
Why Eating Right Matters for Acute Lymphoid Leukemia?
In Acute Lymphoid Leukemia, activation or inhibition of some of the biochemical pathways including MYC Signaling, Hypoxia, MAPK Signaling, Cell Cycle, P53 Signaling, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, Angiogenesis and Growth Factor Signaling plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Acute Lymphoid Leukemia, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Cytarabine treatment for Acute Lymphoid Leukemia
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Acute Lymphoid Leukemia considering only one specific treatment- Cytarabine.
Foods to Avoid with Cytarabine treatment
Adzuki Bean : Adzuki Bean contains active ingredients such as Folic Acid, Genistein, Isoliquiritigenin and others. Folic Acid interferes with the impact of Cytarabine in Acute Lymphoid Leukemia by activating a specific biochemical pathway called MYC Signaling. Hence, avoid foods like Adzuki Bean with Cytarabine treatment for Acute Lymphoid Leukemia (ALL).
Black-eyed Pea : Black-eyed Pea contains active ingredients such as Folic Acid, Genistein, Retinol and others. Folic Acid interferes with the impact of Cytarabine in Acute Lymphoid Leukemia by activating a specific biochemical pathway called MYC Signaling. Hence, avoid foods like Black-eyed Pea with Cytarabine treatment for Acute Lymphoid Leukemia (ALL).
Foods to Eat with Cytarabine treatment
Almond : Almond contains active ingredients like Geraniin, Salicylic Acid and Quercetin. Intake of Geraniin along with Cytarabine treatment for Acute Lymphoid Leukemia causes a decrease in a specific biochemical pathway which is called Hypoxia, and this is a very positive effect. Almond hence should be eaten with Cytarabine treatment for Acute Lymphoid Leukemia. (Antonio Vassallo et al, PLoS One., 2013; Silvia Sironi et al, Sci Rep., 2015)
Bayberry : Bayberry contains active ingredients like Beta-carotene, Salicylic Acid and Caffeic Acid. Intake of Beta-carotene along with Cytarabine treatment for Acute Lymphoid Leukemia causes a decrease in a specific biochemical pathway which is called Hypoxia, and this is a very positive effect. Bayberry hence should be eaten with Cytarabine treatment for Acute Lymphoid Leukemia. (Yoo-Sun Kim et al, J Nutr Biochem., 2014; Silvia Sironi et al, Sci Rep., 2015)
Should I take this Nutritional Supplement with Cytarabine treatment?
Black Seed : Black Seed has no known reported CYP (drug metabolizing enzyme) interactions with Cytarabine treatment. Black Seed supports the Cytarabine treatment for Acute Lymphoid Leukemia by decreasing the biochemical pathways such as MAPK Signaling, MYC Signaling, and PI3K-AKT-MTOR Signaling.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
What are the Symptoms of Acute Lymphoid Leukemia?
In the initial stages, most cancers including Acute Lymphoid Leukemia may not cause any signs or symptoms. However, as the disease progresses, Acute Lymphoid Leukemia may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Acute Lymphoid Leukemia.
- Frequent infections
- Pale skin
- Fever with high temperature
- Weakness and fatigue
- Frequent bleeding from gums or nosebleeds
- Night sweats
- Bone/joint pain
- Easy bleeding and bruising of the skin
- Swollen lymph nodes in the neck, armpits, abdomen or groin
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Acute Lymphoid Leukemia.
What are the Treatment Options for Acute Lymphoid Leukemia?
The treatment for Acute Lymphoid Leukemia may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, and whether the cancer was just diagnosed or had come back. The treatment options for Acute Lymphoid Leukemia include:
- Bone marrow transplantation
- Radiation therapy
- (CAR)-T cell therapy
- Targeted therapy
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Acute Lymphoid Leukemia (ALL).
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Acute Lymphoid Leukemia.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Personalized Nutrition for Cancer!
Cancer changes with time. Customize and modify your nutrition based on cancer indication, treatments, lifestyle, food preferences, allergies and other factors.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.