No two cancers are the same and neither should your nutrition be. The most commonly asked question to dieticians and oncologists globally is “What Should I Eat?”. The answer is “It Depends”. It depends on the type of cancer, current treatment and supplements being taken, age, gender, BMI, lifestyle and any genetic information available. In short – the answer to “What Should I Eat” for Burkitt Lymphoma needs to be personalized to minimize adverse interactions between nutrition (from foods/diet) and treatment, and to improve symptoms.
Foods like Almond and Bamboo should be eaten when undergoing Cyclophosphamide treatment for Burkitt Lymphoma. On the same lines, avoid foods like Acorn and Buttermilk with treatment of Cyclophosphamide for Burkitt Lymphoma. Similarly, Black Seed contains an active ingredient called Thymoquinone. Thymoquinone has CYP (drug metabolizing enzyme) interactions with Cyclophosphamide treatment and hence should be avoided.
You get the point – your nutrition needs to be personalized and it needs to be re-evaluated as soon as any of the conditions change. Create and follow a nutrition plan personalized to you to minimize adverse interactions of nutrition for cancers like Burkitt Lymphoma.
What is Burkitt Lymphoma?
Burkitt Lymphoma is a rare type of Non-Hodgkin’s Lymphoma that develops from the immune cells called B-cells. In the US, this cancer is commonly diagnosed in people who are about 30 years of age, however, it can occur in people of any age. In Africa, this cancer is commonly found in children between 5-10 years of age. It is more commonly found in men as compared to women.
Burkitt Lymphoma has prevalence of certain genetic changes. Some of the genes such as MYC, ID3, TP53, and CCND3 are known to have genetic abnormalities in this cancer resulting in a change of function.
The genetic abnormalities found in Burkitt Lymphoma can influence specific biochemical pathways to drive these cancer cells to aggressive growth and survive the ongoing treatment. In addition, lifestyle conditions or habits like smoking, alcohol consumption and BMI (Body Mass Index) can have a big influence on the response to your physician prescribed treatments for Burkitt Lymphoma. Numerous studies have consistently shown that your nutrition/diet – both food and nutritional supplements can adversely affect the treatment or be supportive or play no role. Hence, the triangulation of Burkitt Lymphoma genomics, planned or ongoing therapies and lifestyle need to be thoroughly considered to make decisions on what foods and supplements to consider and avoid while designing diet/nutrition plan. Also, it is important to note that when any of these conditions change, like treatment or lifestyle or cancer diagnosis – it may impact the nutrition and the nutrition/diet plan for Burkitt Lymphoma nutrition may have to be redesigned.
Why Eating Right Matters for Burkitt Lymphoma?
In Burkitt Lymphoma, activation or inhibition of some of the biochemical pathways including Myc Signaling, MAPK Signaling, Cell Cycle Checkpoints, Cancer Epigenetics, Cell Cycle, P53 Signaling, Vitamin D Signaling, PI3K-AKT-MTOR Signaling, Angiogenesis, Amino Acid Metabolism, Apoptosis and Dna Repair plays an important role in driving the disease. All foods and nutritional supplements contain active ingredients which have a specific molecular action on different biochemical pathways. Hence, while the intake of certain foods and nutritional supplements as part of the diet may support a specific treatment of Burkitt Lymphoma, eating few other foods and supplements may lead to adverse interactions with the treatment or may increase the cancer progression.
Example Foods to “Not Eat” and Eat with Cyclophosphamide treatment for Burkitt Lymphoma
The nutrition for cancer always depends on the type of cancer, treatments and supplements being taken (if any), age, gender, BMI, lifestyle and any genetic information available. Here we show an example of nutrition/diet for Burkitt Lymphoma considering only one specific treatment- Cyclophosphamide.
Foods to Avoid
Acorn : Acorn contains active ingredients such as Folic Acid, Retinol and others. Folic Acid interferes with the impact of Cyclophosphamide in Burkitt Lymphoma by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Acorn with Cyclophosphamide treatment for Burkitt Lymphoma.
Buttermilk : Buttermilk contains active ingredients such as Lauric Acid, Myristic Acid, Vitamin D3 and others. Lauric Acid interferes with the impact of Cyclophosphamide in Burkitt Lymphoma by activating a specific biochemical pathway called PI3K-AKT-MTOR Signaling. Hence, avoid foods like Buttermilk with Cyclophosphamide treatment for Burkitt Lymphoma.
Foods to Eat
Almond : Almond contains active ingredients like Geraniin, Salicylic Acid and Quercetin. Intake of Geraniin along with Cyclophosphamide treatment for Burkitt Lymphoma causes a decrease in a specific biochemical pathway which is called PI3K-AKT-MTOR Signaling, and this is a very positive effect. Almond hence should be eaten with Cyclophosphamide treatment for Burkitt Lymphoma. (Yanmao Wang et al, Anticancer Drugs., 2017; Maria Bhatti et al, Oncotarget., 2018)
Bamboo : Bamboo contains active ingredients like Oleic Acid, Vitamin C and Citric Acid. Intake of Oleic Acid along with Cyclophosphamide treatment for Burkitt Lymphoma causes a decrease in a specific biochemical pathway which is called Cell Cycle, and this is a very positive effect. Bamboo hence should be eaten with Cyclophosphamide treatment for Burkitt Lymphoma. (Lin Jiang et al, Scientific Reports, 2017; , A Pajic et al, Int J Cancer., 2000)
Should I take this Nutritional Supplement for Burkitt Lymphoma?
Black Seed : Black Seed nutritional supplements contain active ingredients such as Thymoquinone which have CYP3A4 interactions with Cyclophosphamide treatment, and hence should not be used. Also, Black Seed supplement does not show benefit on other biochemical pathways that could improve the Cyclophosphamide treatment efficacy in Burkitt Lymphoma. (Ahmed A Albassam et al, Saudi Pharm J., 2018; Pius S Fasinu et al, Front Oncol., 2019)
What are the Symptoms of Burkitt Lymphoma?
In the initial stages, most cancers including Burkitt Lymphoma may not cause any signs or symptoms. However, as the disease progresses, Burkitt Lymphoma may start showing symptoms.
Following are some of the signs and symptoms that may be caused by Burkitt Lymphoma.
- Stomach pain
- Swelling of your tummy, neck, armpit or groin
- Unexplained weight loss
- Easy bruising and bleeding
- Night sweats
Though many of these symptoms may also be caused by various other health conditions, consult your doctor if you experience these symptoms to rule out the possible chances of Burkitt Lymphoma.
What are the Treatment Options for Burkitt Lymphoma?
The treatment for Burkitt Lymphoma may be decided based on different factors including the stage and extent of spread of the cancer, cancer characteristics, symptoms, patient’s general health and medical history, and whether the cancer was just diagnosed or had come back. The treatment options for Burkitt Lymphoma include:
- Combination Chemotherapy
- Chemotherapy with Antibody treatment ( Rituximab)
- Intrathecal chemotherapy
As part of the diet, avoid including those foods and supplements that may adversely interact with the treatments for Burkitt Lymphoma.
The two most important things to remember are that cancer treatments and nutrition are never the same for everyone. Nutrition/diet which includes food and nutritional supplements is an effective tool which is controlled by you, while facing cancer such as Burkitt Lymphoma.
What food you eat and which supplements you take is a decision you make. Your decision should include consideration of the cancer gene mutations, which cancer, ongoing treatments and supplements, any allergies, lifestyle information, weight, height and habits.
The nutrition planning for cancer from addon is not based on internet searches. It automates the decision making for you based on molecular science implemented by our scientists and software engineers. Irrespective of whether you care to understand the underlying biochemical molecular pathways or not - for nutrition planning for cancer that understanding is needed.
Get started NOW with your nutrition planning by answering questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, habits, lifestyle, age group and gender.
Foods to Eat After Cancer Diagnosis!
No two cancers are the same. Go beyond the common nutrition guidelines for everyone and make personalized decisions about food and supplements with confidence.
Cancer patients often have to deal with different chemotherapy side effects which affect their quality of life and look out for alternative therapies for cancer. Taking the right nutrition and supplements based on scientific considerations (avoiding guesswork and random selection) is the best natural remedy for cancer and treatment related side-effects.